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Displaying drugs 76 - 100 of 10577 in total

Clobazam

Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi, Frisium, Urbanyl, and others. . Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. Unlike older 1,4-benzodiazepines, clobazam has...
Approved
Illicit
Matched Synonyms: … 7-Chloro-1-methyl-5-phenyl-1,5-dihydro-benzo[b][1,4]diazepine-2,4-dione ... 1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepine …
Matched Iupac: … 7-chloro-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-2,4-dione …
Matched Description: … 2 subunit of the GABAA receptor, which mediates anxiolytic effects, than the α1< …
Matched Products: … Clobazam Essential Pharmaceuticals 1 mg/ml Suspension zum Einnehmen …

Ceforanide

Ceforanide is administered parenterally. It has a longer elimination half-life than any currently available cephalosporin. Its activity is very similar to that of cefamandole, another second-generation cephalosporin antibiotic, except that ceforanide is less active against most gram-positive organisms. Many coliforms, including Escherichia coli, Klebsiella, Enterobacter, and Proteus, are susceptible to...
Approved
Matched Synonyms: … -8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-[[2-[2-(aminomethyl)phenyl]acetyl]amino]-3-[[1-(carboxymethyl)tetrazol-5-yl]sulfanylmethyl] ... 7-[O-(aminomethyl)phenylacetamido]-3-[[[1-(carboxymethyl)-1H-tetrazol-5-yl]thio]methyl]-3-cephem-4-carboxylic …
Matched Iupac: … }methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ... (6R,7R)-7-{2-[2-(aminomethyl)phenyl]acetamido}-3-({[1-(carboxymethyl)-1H-1,2,3,4-tetrazol-5-yl]sulfanyl …

Pentobarbital

A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA...
Approved
Investigational
Vet approved
Matched Synonyms: … 5-ethyl-5-(1-methylbutyl)barbituric acid ... 5-Ethyl-5-(1-methyl-butyl)-pyrimidine-2,4,6-trione ... 5-Ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Methylergometrine

A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)
Approved
Matched Synonyms: … D-lysergic acid 1-butanolamide ... 9,10-Didehydro-N-[1-(hydroxymethyl)-propyl]-D-lysergamide …
Matched Iupac: … (4R,7R)-N-[(2S)-1-hydroxybutan-2-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1 …

Isoprenaline

Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and cardiogenic shock.[A15638,L33160] Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising...
Approved
Investigational
Matched Synonyms: … 1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanol ... 1-(3,4-dihydroxyphenyl)-2-isopropylaminoethanol …
Matched Iupac: … 4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol …
Matched Products: … ENAXİL 1 MG/5 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... Isoproterenol HCl Inj 1:5000 ... ENAXİL 1 MG/5 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET …

Acetohexamide

A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide has been discontinued in the US market.
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-((p-Acetylphenyl)sulfonyl)-3-cyclohexylurea ... 1-[(4-acetylbenzene)sulfonyl]-3-cyclohexylurea 4-acetyl-N-(cyclohexylcarbamoyl)benzenesulfonamide …
Matched Iupac: … 1-(4-acetylbenzenesulfonyl)-3-cyclohexylurea …
Matched Description: … A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. …

Nitrofurantoin

Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts...
Approved
Vet approved
Matched Synonyms: … 1-((5-nitrofurfurylidene)amino)hydantoin ... N-(5-Nitrofurfurylidene)-1-aminohydantoin ... 1-((5-nitro-2-furanyl)methylene)amino-2,4-imidazolidenedione …
Matched Iupac: … 1-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]imidazolidine-2,4-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Chlorphenesin carbamate

Approved
Vet approved
Withdrawn
Matched Synonyms: … 1,2-propanediol-3-(p-chlorophenoxy)-1-carbamate ... 3-(4-chlorophenoxy)-1,2-propanediol-1-carbamate ... 3-(p-chlorophenoxy)-1,2-propanediol 1-carbamate …

Doxercalciferol

Doxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form 1α,25-dihydroxyvitamin D2 (1α,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. Doxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as for the treatment...
Approved
Matched Synonyms: … 1-Hydroxyvitamin D2 ... 1-Hydroxyergocalciferol …
Matched Iupac: … (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden …

Brilliant green cation

Brilliant green, or ethanaminium, is a derivative of triarylmethane dye that has been used as a dye to color silk and wool. Due to its inhibitory actions against Gram positive microorganisms, brilliant green can be found in antiseptic products such as solutions and swabs used to prevent infection.
Approved
Vet approved
Matched Synonyms: … Brilliant green(1+) …
Matched Iupac: … 4-{[4-(diethylamino)phenyl](phenyl)methylidene}-N,N-diethylcyclohexa-2,5-dien-1-iminium …

Olanzapine

Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles clozapine and only differs by...
Approved
Investigational
Matched Synonyms: … 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine …
Matched Iupac: … 5-methyl-8-(4-methylpiperazin-1-yl)-4-thia-2,9-diazatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),3(7),5,8,10,12 …
Matched Salts cas: … 783334-36-1 ... 491828-16-1 …
Matched Mixtures name: … TARGET 12 MG /50 MG KAPSUL, 30 ADET ... FLUXOPIN 12 MG/25 MG KAPSÜL ,30 KAPSÜL ... FLUXOPIN 12 MG/50 MG KAPSÜL ,30 KAPSÜL …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists …

Enmetazobactam

Enmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. Because ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in the treatment of serious infections. The combination product of enmetazobactam and cefepime was first approved by the FDA on February...
Approved
Matched Synonyms: … (2s,3s,5r)-3-methyl-3-((3-methyltriazol-3-ium-1-yl)methyl)-4,4,7-trioxo-4^6-thia-1-azabicyclo(3.2.0)heptane ... -3-yl)methyl)-1-methyl-, inner salt ... 1h-1,2,3-triazolium, 3-(((2s,3s,5r)-2-carboxy-3-methyl-4,4-dioxido-7-oxo-4-thia-1-azabicyclo(3.2.0)hept …
Matched Iupac: … 1-{[(2S,3S,5R)-2-carboxylato-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptan-3-yl]methyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Etelcalcetide

Etelcalcetide is a calcimimetic drug for the treatment of secondary hyperparathyroidism in patients undergoing hemodialysis. Etelcalcetide was approved (trade name Parsabiv) for the treatment of secondary hyperparathyroidism (HPT) in adult patients with chronic kidney disease (CKD) on hemodialysis in February, 2017.
Approved
Investigational
Matched Iupac: … (2R)-2-amino-3-{[(2S)-2-{[(1R)-1-{[(1R)-4-carbamimidamido-1-{[(1R)-4-carbamimidamido-1-{[(1R)-4-carbamimidamido ... -1-{[(1R)-1-{[(1R)-4-carbamimidamido-1-carbamoylbutyl]carbamoyl}ethyl]carbamoyl}butyl]carbamoyl}butyl …
Matched Products: … PARSABİV 5 MG/1 ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 12 ADET ... ENJEKSİYONLUK ÇÖZELTİ, 12 ADET ... ENJEKSİYONLUK ÇÖZELTİ, 12 ADET …

Azacitidine

Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Synonyms: … 4-amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one …
Matched Iupac: … 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ENJEKSİYONLUK SÜSPANSİYON HAZIRLAMAK İÇİN TOZ, 1 ADET ... ENJEKSIYONLUK SÜSPANSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADET ... AZIDA 100 MG SC ENJEKSIYONLUK SÜSPANSIYON IÇIN TOZ IÇEREN FLAKON ,1 ADET …

Alginic acid

Alginic acid, also referred to as algin or alginate, is a hydrophilic or anionic polysaccharide isolated from certain brown seaweed (Phacophycae) via alkaline extraction. It is present in cell walls of brown algae where it forms a viscous gel when binding with water. Alginic acid is a linear polymer consisted...
Approved
Investigational
Matched Synonyms: … (Alginate)n+1 …

Emtricitabine

Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults or combined with tenofovir alafenamide for the prevention of HIV-1 infection in high risk adolescents and adults. Emtricitabine is a cytidine analogue. The drug works by inhibiting HIV reverse transcriptase, preventing transcription of...
Approved
Investigational
Matched Synonyms: … (−)-(2R,5S)-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine ... 5-fluoro-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine ... (−)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one …
Matched Iupac: … 5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-4-imino-1,4-dihydropyrimidin-2-ol …
Matched Description: … of HIV infection in adults[L9019] or combined with [tenofovir alafenamide] for the prevention of HIV-1 …
Matched Categories: … MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …

Tolbutamide

Tolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin...
Approved
Investigational
Matched Synonyms: … 1-Butyl-3-tosylurea ... 1-Butyl-3-(p-tolylsulfonyl)urea ... 1-p-Toluenesulfonyl-3-butylurea …
Matched Iupac: … 3-butyl-1-(4-methylbenzenesulfonyl)urea …

Amlexanox

Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and 50% of...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-Amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3-b)pyridine-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Torasemide

Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.
Approved
Matched Synonyms: … 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea ... N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide …
Matched Iupac: … 1-({4-[(3-methylphenyl)amino]pyridin-3-yl}sulfonyl)-3-(propan-2-yl)urea …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Sodium acetate

Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions. Medically, sodium acetate is important component as an electrolyte replenisher when given intravenously. It is mainly indicated to correct...
Approved
Investigational
Matched Synonyms: … Acetic acid, sodium salt (1:1) …
Matched Mixtures name: … MULTIELECTROLITOS TIPO 1 ... Multiple Electrolyte Additive Liq Formula 1 …

Ertugliflozin

Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes mellitus. It works to block glucose reabsorption from the glomerulus. Ertugliflozin was first approved by the FDA in December 2017.[A261951, L1132] It was also approved by the European Commission in March 2018.
Approved
Investigational
Matched Synonyms: … 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-β-L-idopyranose ... (1S,2S,3S,4R,5S)-5-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane ... β-L-Idopyranose, 1,6-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)- …
Matched Iupac: … (1S,2S,3S,4R,5S)-5-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1 …

Artesunate

Artesunate is indicated for the initial treatment of severe malaria. The World Health Organization recommends artesunate as first line treatment for severe malaria. Artesunate was developed out of a need for a more hydrophilic derivative of artemisinin. Artesunate was granted FDA approval on 26 May 2020.
Approved
Investigational
Matched Synonyms: … butanedioic acid, 1-[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[ …

Piperaquine

Piperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China . Its use declined in the 1980's as piperaquine resistant strains of Plasmodium falciparum appeared and artemisinin derivatives became available. It has come back into use in combination with the artemisinin derivative DB11638 as part of...
Approved
Experimental
Investigational
Matched Synonyms: … 1,3-bis[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propane …
Matched Iupac: … 7-chloro-4-(4-{3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl}piperazin-1-yl)quinoline …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Penbutolol

Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker. Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug. Penbutolol also demonstrates high binding affinity to the...
Approved
Investigational
Matched Synonyms: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Iupac: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Description: … Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker …

Ombitasvir

Ombitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Synonyms: … -2,1-diyl[(2S)-3-methyl-1-oxobutane-1,2-diyl]})biscarbamate ... dimethyl ([(2S,5S)-1-(4-tert-butylphenyl)pyrrolidine-2,5-diyl]bis{(4,1-phenylene)carbamoyl(2S)pyrrolidine …
Matched Iupac: … methyl N-[(2S)-1-[(2S)-2-({4-[(2S,5S)-1-(4-tert-butylphenyl)-5-{4-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino ... -1-oxobutan-2-yl]carbamate ... ]-3-methylbutanoyl]pyrrolidine-2-amido]phenyl}pyrrolidin-2-yl]phenyl}carbamoyl)pyrrolidin-1-yl]-3-methyl …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... DB00503], and [DB00811] with the intent to cure, or achieve a sustained virologic response (SVR), after 12 …
Displaying drugs 76 - 100 of 10577 in total