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Displaying drugs 76 - 100 of 8070 in total

Sulfoxone

Sulfoxone is a water-soluble sulfone used as an antileprosy drug. It has been used with limited success in the treatment of dermatitis herpetiformis.
Approved
Matched Description: … It has been used with limited success in the treatment of dermatitis herpetiformis. …
Matched Categories: … Drugs for Treatment of Lepra …

Naphazoline

Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807]. Naphazoline was first developed in 1942 as a nasal formulation for congestion .
Approved
Investigational
Matched Description: … Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles …
Matched Mixtures name: … FENIXIL-OF …

Valproate bismuth

Valproate bismuth is available in Canada in the over-the-counter medication Neo-Laryngobis.
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Iofetamine I-123

Approved
Matched Categories: … Diagnostic Uses of Chemicals ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Clostridium tetani toxoid antigen (formaldehyde inactivated)

Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection. It is used for active immunization of children 7 years of age or older, and adults, for prevention of tetanus. The toxoid in the Clostridium tetani culture is grown and detoxified followed by purification via ammonium sulfate filtration...
Approved
Matched Description: … It is used for active immunization of children 7 years of age or older, and adults, for prevention of …
Matched Mixtures name: … FINAL BULK OF ADSORBED TD VACCINE …

Terizidone

Terizidone has been used in trials studying the treatment of Tuberculosis, HIV Infections, Multidrug Resistant Tuberculosis, and Extensively-drug Resistant Tuberculosis.
Approved
Investigational
Matched Description: … Terizidone has been used in trials studying the treatment of Tuberculosis, HIV Infections, Multidrug …
Matched Categories: … Drugs for Treatment of Tuberculosis …

Trolamine

Trolamine, which is also referred to as triethanolamine (TEA), is a tertiary amine and a triol. It is a bifunctional compound that exhibits both properties of alcohols and amines. Trolamine contains small amounts of diethanolamine and ethanolamine and may also act as an antioxidant against the auto-oxidation of animal and...
Approved
Matched Description: … against the auto-oxidation of animal and vegetable fats [A27174]. ... It is a bifunctional compound that exhibits both properties of alcohols and amines. ... Trolamine contains small amounts of diethanolamine and ethanolamine and may also act as an antioxidant …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …

Procaine

A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Description: … A local anesthetic of the ester type that has a slow onset and a short duration of action. …
Matched Categories: … Esters of Aminobenzoic Acid ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Cyclosporine

Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus Beauveria nivea. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products...
Approved
Investigational
Vet approved
Matched Products: … Cyclosporine/Chondroitin PF ... Cyclosporine/Chondroitin Sulfate PF …

Human adenovirus b serotype 7

Human adenovirus b serotype 7 is a vaccine.
Approved

Mefloquine

Malaria is a protozoan disease that places an enormous burden on human health in endemic areas around the world. The 2020 World Health Organization malaria report indicates a 60% decrease in the global malaria fatality rate between 2000 to 2019. Despite this, malaria remains a significant cause of morbidity and...
Approved
Investigational
Matched Description: … [L30618] Despite this, malaria remains a significant cause of morbidity and mortality; 90% of deaths ... effects; product information warns of potential serious neuropsychiatric effects. ... nonimmune civilian and military travelers, pregnant women, and immigrants traveling to their place of …
Matched Mixtures name: … อาร์ทีซูเนทและเมฟลอควินไฮโดรคลอไรด์ 25/55 มก. …

Davesomeran

Davesomeran is a mRNA vaccine used in conjunction with elasomeran as part of the Moderna Bivalent COVID-19 vaccine. Similar to the previous Moderna COVID-19 vaccine, Moderna Bivalent vaccine encodes the full-length pre-fusion stabilized spike (S) protein to elicit an immune response.[L43882,L28026] However, with the addition of davesomeran, Moderna Bivalent vaccine...
Approved
Investigational
Matched Description: … against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variants. ... demonstrated that the Moderna Bivalent vaccine elicit a higher seroresponse both against the original SARS-CoV ... -2 strain and the BA.4/5 strain compared to that of the Moderna COVID-19 Vaccine. …

Pheneticillin

Pheneticillin (or phenethicillin) is a penicillin antibiotic which is approved for use internationally.
Approved
Matched Categories: … combinations of penicillins …

Adenovirus type 7 vaccine live

Approved

Omidenepag isopropyl

Omidenepag isopropyl is a topical ocular hypotensive agent used to reduce intraocular pressure (IOP) in patients with glaucoma and ocular hypertension. Omidenepag isopropyl is quickly metabolized to its active metabolite, omidenepag, a molecule with high selectivity and agonistic activity towards the prostaglandin E2 (EP2) receptor.[A253263,A253268] Prostanoid FP receptor agonists (FP...
Approved
Investigational
Matched Description: … [A253268] In September 2022, the FDA approved the use of omidenepag isopropyl.[L43503] ... The use of an EP2 receptor agonist such as omidenepag represents an alternative in these scenarios. ... [A253263,A253268] Prostanoid FP receptor agonists (FP agonists), such as [latanoprost], are part of the …
Matched Categories: … combinations of sulfonamides …

Artemisia vulgaris root

Artemisia vulgaris root allergenic extract is used in allergenic testing.
Approved
Investigational

Imelasomeran

Imelasomeran was first approved in Canada on September 1, 2022, as one-half of Moderna's Spikevax Bivalent COVID-19 mRNA vaccine. It encodes for the viral spike protein of the Omicron BA.1 variant of SARS-CoV-2, a particularly infectious variant of concern first documented in 2021.
Approved
Investigational
Matched Description: … [L45320] It encodes for the viral spike protein of the Omicron BA.1 variant of SARS-CoV-2, a particularly ... infectious variant of concern first documented in 2021. ... Imelasomeran was first approved in Canada on September 1, 2022, as one-half of Moderna's Spikevax Bivalent …

Threonine

An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.
Approved
Nutraceutical
Matched Mixtures name: … Aminosyn-PF ... Aminosyn-PF ... Aminosyn-PF …

Tryptophan

An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit...
Approved
Nutraceutical
Withdrawn
Matched Description: … It is a precursor of indole alkaloids in plants. ... It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). …
Matched Mixtures name: … Aminosyn-PF ... Aminosyn-PF ... Aminosyn-PF …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Glymidine

Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and increasing the sensitivity of peripheral tissues to insulin. The mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta...
Approved
Investigational
Matched Description: … The mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating ... the release of insulin from functioning pancreatic beta cells, and increasing sensitivity of peripheral ... and increasing the sensitivity of peripheral tissues to insulin. …
Matched Categories: … combinations of sulfonamides …

AstraZeneca COVID-19 Vaccine

The AstraZeneca COVID-19 Vaccine (previously known as ChAdOx1 nCoV-19 or AZD1222) is one of several vaccines developed in 2020 for the prevention of COVID-19 caused by SARS-CoV-2.[L12669,L32649] The ChAdOx1 viral vector was developed at the University of Oxford and has been investigated as a potential vector for vaccines against another...
Approved
Investigational
Matched Description: … 18 and 55. ... developed in 2020 for the prevention of COVID-19 caused by SARS-CoV-2. ... adenovirus capable of producing the spike (S) protein of SARS-CoV-2, allowing for the formation of endogenous …

Lysine

Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as...
Approved
Nutraceutical
Matched Description: … Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl ... O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain …
Matched Mixtures name: … Aminosyn-PF ... Aminosyn-PF ... Aminosyn-PF …

Pseudoephedrine

Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Description: … [A188823] The decongestant effect of pseudoephedrine was described in dogs in 1927.[A188823] ... [A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional …
Matched Mixtures name: … Hot Lemon Relief for Symptoms Of Cough, Cold and Flu ... Hot Lemon Relief for Symptoms Of Cough, Cold and Flu Extra Strength ... Hot Lemon Relief for Symptoms Of Cough, Cold and Flu Ultra Strength …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Tamsulosin

Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common.[Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy.[Label] Antagonism of these receptors leads to relaxation of smooth muscle in...
Approved
Investigational
Matched Description: … [Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy. ... [Label] Antagonism of these receptors leads to relaxation of smooth muscle in the prostate and detrusor ... antagonists developed in the 1980s were less selective and more likely to act on the smooth muscle of …
Matched Categories: … combinations of sulfonamides …
Matched Products: … TAMABLAN PF …

Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine

Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine is used to prevent invasive meningococcal disease, which is caused by bacteria Neisseria meningitidis entering the bloodstream and invading the blood-brain barrier to cause a variety of infections such as septicemia, meningitis, and pneumonia. Several serogroups of N....
Approved
Matched Description: … [A253277] Several serogroups of _N. meningitidis_ - A, B, C, Y, and W-135 - known to cause meningococcal ... Neisseria meningitidis_ entering the bloodstream and invading the blood-brain barrier to cause a variety of ... Corynebacterium diphtheriae_ CRM197 protein carrier, resulting in four drug substances contained in each dose of …
Displaying drugs 76 - 100 of 8070 in total