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Displaying drugs 976 - 1000 of 1070 in total

Cephalexin

Cephalexin is the first of the first generation cephalosporins.[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,Label] Cephalexin was approved by the FDA on 4 January 1971.
Approved
Investigational
Vet approved
Matched Description: … [A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. …
Matched Products: … IELEXIN 500 MG FILM TABLET ... MAKSIPOR 1 GR FILM TABLET, 10 ADET ... MAKSIPOR 1 GR FILM TABLET, 20 ADET …

Rubidium Rb-82

Rubidium chloride Rb-82 injection is a sterile nonpyrogenic solutions of rubidium Rb 82 chloride. It is indicated for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic stress conditions to evaluate regional myocardial perfusion in adult patients with suspected or existing coronary artery disease.
Approved
Investigational
Matched Products: … Ruby-fill …

Sirolimus

Sirolimus, also known as rapamycin, is a macrocyclic lactone antibiotic produced by bacteria Streptomyces hygroscopicus, which was isolated from the soil of the Vai Atari region of Rapa Nui (Easter Island). It was first isolated and identified as an antifungal agent with potent anticandida activity; however, after its potent antitumor...
Approved
Investigational
Matched Description: … extensively investigated as an immunosuppressive and antitumour agent. ... [A242412] It was first isolated and identified as an antifungal agent with potent anticandida activity ... ; however, after its potent antitumor and immunosuppressive activities were later discovered, it was …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Sirolimus and Prodrugs …
Matched Products: … RAPAMUNE 1 MG 100 FILM DRAJE ... RAPAMUNE 1 MG FILM DRAJE, 30 ADET …

Vitex agnus-castus fruit extract

Vitex agnus-castus fruit extract is obtained from dry fruits of Vitex agnus-castus. The fruits contain mixture of iridoids, flavonoids and compounds in leaves and flowers that structurally resemble sex hormones. Clinical studies demonstrates effectiveness of vitex agnus-castus fruit extract in the management of premenstrual stress syndrome (PMS) and cyclical breast...
Experimental
Matched Description: … The fruits contain mixture of iridoids, flavonoids and compounds in leaves and flowers that structurally ... μ (mu) - and δ (delta) -opioid receptors. ... effectiveness of vitex agnus-castus fruit extract in the management of premenstrual stress syndrome (PMS) and …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … AGNUCASTON FILM TABLET, 30 ADET …

Sorafenib

Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also...
Approved
Investigational
Matched Description: … Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. ... in tumour cell proliferation and tumour angiogenesis. ... It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … NEXAVAR FILM-COATED TABLETS 200 MG ... NEXAVAR 200 MG FILM KAPLI TABLET, 112 ADET …

Nabumetone

Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Matched Description: … Nabumetone was developed by Smithkline Beecham under the trade name Relafen and first received FDA approval …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … NABUFEX 500 MG FILM TABLET, 10 ADET ... NABUFEX 500 MG FILM TABLET, 30 ADET …

{[2-Amino-4-oxo-6,7-di(sulfanyl-κS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum

Experimental
Matched Name: … {[2-Amino-4-oxo-6,7-di(sulfanyl-κS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato …

Penbutolol

Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker. Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug. Penbutolol also demonstrates high binding affinity to the...
Approved
Investigational
Matched Description: … Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker ... Penbutolol is contraindicated in patients with cardiogenic shock, sinus bradycardia, second and third ... degree atrioventricular conduction block, bronchial asthma, and those with known hypersensitivity. …
Matched Categories: … penbutolol and other diuretics …
Matched Products: … BETAPRESSİN 40 MG FİLM TABLET, 30 TABLET …

Rifapentine

Rifapentine is an antibiotic drug used in the treatment of tuberculosis. It inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme.
Approved
Investigational
Matched Products: … PRIFTIN FILM COATED TABLETS 150MG …

Ospemifene

Ospemifene is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. FDA approved on February 26, 2013.
Approved
Investigational
Matched Description: … modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …
Matched Products: … SENSHIO FILM-COATED TABLET 60MG …

Fidaxomicin

Fidaxomicin is a novel macrolide antibiotic used in the treatment of diarrhea caused by Clostridioides (formerly Clostridium) difficile in adult and pediatric patients over the age of 6 months. Fidaxomicin is a naturally-occurring 18-member macrocycle derived from fermentation. Because fidaxomicin contains an 18-membered lactone ring in its structure, it is...
Approved
Matched Description: … the treatment of diarrhea caused by _Clostridioides_ (formerly _Clostridium_) _difficile_ in adult and ... bactericidal activity is time-dependent, and not concentration-dependent. ... [A190492] The antibacterial activity of fidaxomicin is distinct from macrolides and rifamycins, as the …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … DİFİCLİR 200 MG FİLM KAPLI TABLET, 20 ADET …

Cabotegravir

Cabotegravir, or GSK1265744, is an HIV-1 integrase inhibitor that is prescribed with the non-nucleoside reverse transcriptase inhibitor, rilpivirine.[A227668,L31188,L31193] Early research into cabotegravir showed it had lower oral bioavailability than dolutegravir, which resulted in the development of long acting monthly intramuscular injection formulation for cabotegravir.[A227668,L31193] Cabotegravir was granted FDA approval on...
Approved
Investigational
Matched Description: … combination product was granted FDA approval for dosing every two months on February 01, 2022 [L40084] and …
Matched Products: … Vocabria 30 mg Film Kaplı Tablet, 30 ADET …

Oxolinic acid

Experimental
Matched Products: … OKSOLIN ENTERİK FİLM TABLET, 14 ADET …

Sotorasib

Sotorasib, also known as AMG-510, is an acrylamide-derived KRAS inhibitor developed by Amgen.[A187547,A187556] It is indicated in the treatment of adult patients with KRAS G12C mutant non-small cell lung cancer. This mutation makes up >50% of all KRAS mutations. Mutant KRAS discovered in 1982 but was not considered a druggable...
Approved
Investigational
Matched Description: … [A187547] The drug [MRTX849] is also currently being developed and has the same target. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … LUMAKRAS 120 MG FİLM KAPLI TABLET, 240 ADET …

Dasabuvir

Dasabuvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Description: … categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and ... [DB00503] for genotype 1b and with [DB00811] for genotype 1a of Hepatitis C [L852]. ... recommendation published in 2016, the American Association for the Study of Liver Diseases (AASLD) and …
Matched Categories: … dasabuvir, ombitasvir, paritaprevir and ritonavir …
Matched Products: … EXVIERA 250 MG FILM KAPLI TABLET,56 TABLET …

Horse chestnut

Horse chestnut is a flowering plant commonly referred to as Aesculus hippocastanum. Unprocessed horse chestnut seeds contain a toxin called esculin (also spelled aesculin) that increases the risk of bleeding due to anticoagulant actions. These seeds are processed to remove the toxic component, resulting in purified horse chestnut seed extract...
Experimental
Matched Description: … reduces swelling and inflammation of the legs. ... component of this pure extract is escin, or aescin, that promotes blood circulation through the veins and ... Horse chestnut is a flowering plant commonly referred to as *Aesculus hippocastanum*. …
Matched Products: … VENOTREX 50 MG DEĞİŞTİRİLMİŞ SALIMLI FİLM KAPLI TABLET, 60 ADET …

Ferrous fumarate

Used in treatment of iron deficiency anemia.
Approved
Matched Mixtures name: … Luna Vitamin and Mineral Bar for Women ... DAILY-ONE 45 FILM TABLET ... and Succinic Acid …
Matched Categories: … Blood and Blood Forming Organs ... Diet, Food, and Nutrition ... ferrous fumarate and folic acid …
Matched Products: … FEFUR TABLET (FILM-COATED) 100MG ... FERROTAB-200 TABLET (FILM COATED) …

Ritonavir

Ritonavir is an HIV protease inhibitor that interferes with the reproductive cycle of HIV. Although it was initially developed as an independent antiviral agent, it has been shown to possess advantageous properties in combination regimens with low-dose ritonavir and other protease inhibitors. It is now more commonly used as a...
Approved
Investigational
Matched Description: … formulations and as capsules. ... - and Health Canada-approved product Technivie. ... protease inhibitors such as [DB09297] and overall drug exposure. …
Matched Mixtures name: … Lopinavir and Ritonavir ... Lopinavir and ritonavir ... Lopinavir and ritonavir …
Matched Categories: … lopinavir and ritonavir ... darunavir and ritonavir ... atazanavir and ritonavir ... nirmatrelvir and ritonavir ... ombitasvir, paritaprevir and ritonavir …
Matched Products: … Ritonavir film coated ... NORVIR 100 MG FILM TABLET, 30 ADET …

Pivmecillinam

Pivmecillinam is a mecillinam prodrug, a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin. [PubChem]
Approved
Matched Description: … It is active against gram-negative organisms and used as for amdinocillin. [PubChem] …
Matched Products: … Selexid 400 mg film-coated tablets …

Imidafenacin

Imidafenacin is an antispasmodic agent with anticholinergic effects. It antagonizes muscarinic receptors in the bladder to reduce the frequency of urination in the treatment of overactive bladder. It is marketed in Japan under the tradenames Staybla by Ono Pharmaceutical and Uritos by Kyojin Pharmaceutical.
Investigational
Matched Description: … It is marketed in Japan under the tradenames Staybla by Ono Pharmaceutical and Uritos by Kyojin Pharmaceutical …
Matched Categories: … Drugs for Urinary Frequency and Incontinence ... Genito Urinary System and Sex Hormones …
Matched Products: … Uritos Film Coated Tablets 0.1mg …

Tedizolid

Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Investigational
Matched Description: … [L11232, A199086, A199050] Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist ... ) and is generally more effective and more tolerable than [linezolid]. ... such as methicillin-resistant _Staphylococcus aureus_, vancomycin-resistant _Enterococcus faecium_, and …
Matched Products: … SIVEXTRO FILM-COATED TABLET 200MG …

Agomelatine

Agomelatine is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. Agomelatine was developed in Europe by Servier Laboratories Ltd. and submitted to the European Medicines Agency (EMA) in 2005. The Committee...
Approved
Investigational
Matched Description: … Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors ... Agomelatine was developed in Europe by Servier Laboratories Ltd. and submitted to the European Medicines ... The major concern was that efficacy had not been sufficiently shown. …
Matched Products: … VALDOXAN 25MG FILM-COATED TABLETS ... VALDOXAN 25 MG FILM KAPLI TABLET, 28 ADET …

Azacitidine

Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Description: … As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and ... inhibiting protein and DNA synthesis. ... [A1407] Due to its anti-neoplastic activity and its ability to inhibit methylation in replicating DNA …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Onureg 200 mg Film Kaplı Tablet, 7 ADET ... Onureg 300 mg Film Kaplı Tablet, 7 ADET ... Onureg 200 mg Film Kaplı Tablet, 14 ADET …

Pentoxifylline

Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for its possible...
Approved
Investigational
Matched Description: … also has both anti-oxidant and anti-inflammatory properties. ... (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and ... Pharmaceuticals and APOTEX have been available since the late 1990s. …
Matched Products: … TRENTAL 400 FILM-COATED TABLET 400 mg ... TRENTAL CR 600 MG FILM KAPLI TABLET, 20 ADET ... TRENTILIN RETARD 600 MG FILM TABLET, 20 ADET …

Telbivudine

Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.
Approved
Investigational
Matched Description: … Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects …
Matched Categories: … Nucleosides and Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Matched Products: … SEBIVO 600 MG FILM KAPLI TABLET, 28 ADET …
Displaying drugs 976 - 1000 of 1070 in total