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Displaying drugs 126 - 150 of 850 in total

Acetylsalicylic acid

Also known as Aspirin, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction...
Approved
Vet approved
Matched International brands: … Solprin acid …
Matched Synonyms: … Salicylic acid acetate ... 2-Acetoxybenzoic acid ... o-acetoxybenzoic acid …
Matched Name: … Acetylsalicylic acid …
Matched Iupac: … 2-(acetyloxy)benzoic acid …
Matched Description: … Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. ... Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain ... Acetylsalicylic acid is a very common cause of accidental poisoning in young children. …
Matched Mixtures name: … C T Acetylsalicylic Acid Codeine and Caf Tab ... Acetylsalicylic Acid, Caffeine and 8 Mg Codeine Phosphate ... Clopidogrel/acetylsalicylic Acid Mylan …
Matched Categories: … Salicylic Acid and Derivatives ... codeine and acetylsalicylic acid ... sotalol and acetylsalicylic acid ... oxycodone and acetylsalicylic acid ... bisoprolol and acetylsalicylic acid …
Matched Products: … UNIASPIRIN (Acetyl Salicylic Acid Soluble Tablet 300 mg) ... MILLISPIRIN Acetyl Salicylic Acid Soluble Tablets 300 mg (Aspirin) ... Up and Up Aspirin …

Aminobenzoic acid

A member of the vitamin B complex. It used to be common in sunscreening agents until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.
Approved
Experimental
Matched Synonyms: … Aminobenzoic acid ... 4-aminobenzoic acid ... p-Aminobenzoic acid …
Matched Name: … Aminobenzoic acid …
Matched Iupac: … 4-aminobenzoic acid …
Matched Categories: … Emollients and Protectives ... 4-Aminobenzoic Acid ... aminobenzoic acid …

Aminohippuric acid

The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Approved
Investigational
Matched Synonyms: … Aminohippuric acid ... 4-aminohippuric acid ... p-aminohippuric acid …
Matched Name: … Aminohippuric acid …
Matched Iupac: … 2-[(4-aminophenyl)formamido]acetic acid …
Matched Description: … The glycine amide of 4-aminobenzoic acid. ... Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory …
Matched Categories: … aminohippuric acid ... Indicators and Reagents ... Benzamides and benzamide derivatives ... Tests for Renal Function and Ureteral Injuries …

Ioxitalamic acid

Ioxitalamate is an ionic iodinated contrast medium. It is a first-generation contrast media formed by an ionic monomer with a high osmolarity of 1500-1800 mOsm/kg. Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Liebel-Flarshem Canada Inc and approved by Health Canada in 1995. Until the...
Approved
Matched Synonyms: … Ioxitalamic acid …
Matched Name: … Ioxitalamic acid …
Matched Iupac: … 3-acetamido-5-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodobenzoic acid …
Matched Description: … [A33006] Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Liebel-Flarshem ... Canada Inc and approved by Health Canada in 1995. …
Matched Categories: … ioxitalamic acid …

Salsalate

Salsalate is a nonsteroidal anti-inflammatory agent for oral administration. Salsalate's mode of action as an anti-inflammatory and antirheumatic agent may be due to inhibition of synthesis and release of prostaglandins. The usefulness of salicylic acid, the active in vivo product of salsalate, in the treatment of arthritic disorders has been...
Approved
Matched Synonyms: … Salicylic acid bimolecular ester ... Disalicylic acid ... o-Salicylsalicylic acid …
Matched Iupac: … 2-(2-hydroxybenzoyloxy)benzoic acid …
Matched Description: … The usefulness of salicylic acid, the active in vivo product of salsalate, in the treatment of arthritic ... Such capacity limited biotransformation results in an increase in the half-life of salicylic acid from ... Salicylic acid (the active metabolite) biotransformation is saturated at anti-inflammatory doses of salsalate …
Matched Categories: … Salicylic Acid and Derivatives …

Pralatrexate

Pralatrexate is an antifolate for the treatment of relapsed or refractory peripheral T-cell lymphoma . Pralatrexate was developed in response due to the inferior responses of patients using the standard therapy for their B-cells counterparts. Compared to methotrexate, pralatrexate has better accumulation in cancer cells. Pralatrexate is designed to have...
Approved
Investigational
Matched Synonyms: … N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid ... (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}amino)pentanedioic acid ... (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid …
Matched Iupac: … (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid …
Matched Description: … lung cancer, breast cancer, and bladder cancer. ... higher affinity for the reduced folate carrier, a protein that is overexpressed in malignant cells and ... [L37674] It is also being studied for other types of lymphoma and solid malignancy such as non-small-cell …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists …

Bromfenac

Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Synonyms: … [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid ... 2-amino-3-(4-bromobenzoyl)benzeneacetic acid …
Matched Iupac: … 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid …
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record …

Mebendazole

A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Approved
Vet approved
Matched Synonyms: … (5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester …
Matched Iupac: … methyl N-(6-benzoyl-1H-1,3-benzodiazol-2-yl)carbamate …
Matched Description: … A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …

Methotrexate

Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Synonyms: … N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid ... 4-amino-10-methylfolic acid ... 4-amino-N(10)-methylpteroylglutamic acid …
Matched Iupac: … -[(4-{[(4-amino-2-imino-2,3-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid …
Matched Description: … Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and ... inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Folic Acid Analogues ... Folic Acid Antagonists ... Nucleic Acid Synthesis Inhibitors …

Levoleucovorin

Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin). Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the levo-isomer has been shown to be...
Approved
Investigational
Matched Synonyms: … N-[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic ... acid ... L-Folinic acid …
Matched Iupac: … -amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid …
Matched Description: … acid or leucovorin). ... Levoleucovorin is the enantiomerically active form of Folinic Acid (also known as 5-formyl tetrahydrofolic ... acid antagonists, such as methotrexate, which act by inhibiting the enzyme dihydrofolate reductase ( …
Matched Categories: … Folic Acid and Derivatives ... Folic Acid Analogues ... Enzymes and Coenzymes …

Dronedarone

Dronedarone is a Class III antiarrhythmic drug that works to restore the normal sinus rhythm in patients with paroxysmal or persistent atrial fibrillation. Atrial fibrillation is a common sustained arrhythmia where the treatment primarily focuses on stroke prevention and symptom management. It is managed by rate control, rhythm control, prevention...
Approved
Matched Synonyms: … N-(2-butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)-methanesulfonamide ... N-(2-butyl-3-(p-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)methanesulfonamide …
Matched Iupac: … N-(2-butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)methanesulfonamide …
Matched Description: … toxicities, such as thyroid and pulmonary toxicities. ... calcium ion channels and inhibiting β-adrenergic receptors. ... It is managed by rate control, rhythm control, prevention of thromboembolic events, and treatment of …

Oxybenzone

Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Approved
Investigational
Matched Synonyms: … 2-Benzoyl-5-methoxyphenol …
Matched Iupac: … 2-benzoyl-5-methoxyphenol …
Matched Description: … It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays …
Matched Mixtures name: … Silk and Shine ... Skin So Soft Firm and Restore Neck and Chest Treatment ... Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit …

Fenbufen

Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. Fenbufen acts by...
Approved
Matched Synonyms: … 3-(4-Phenylbenzoyl)propionic acid ... 4-(4-Biphenylyl)-4-oxobutyric acid ... 3-(4-Biphenylylcarbonyl)propionic acid …
Matched Iupac: … 4-{[1,1'-biphenyl]-4-yl}-4-oxobutanoic acid …
Matched Description: … It can also be used to relieve backaches, sprains, and fractures. ... anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and ... Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …

Methyl salicylate

Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. The compound was first extracted and isolated from plant species Gaultheria procumbens in 1843. It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and...
Approved
Vet approved
Matched Synonyms: … 2-Hydroxybenzoic acid methyl ester …
Matched Description: … It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and liniments. ... It forms a colorless to yellow or reddish liquid and exhibits a characteristic odor and taste of wintergreen ... It is used as a flavoring agent in chewing gums and mints in small concentrations and added as antiseptic …
Matched Mixtures name: … Walgreens Cool and Heat Muscle and Joint Relief ... Up and Up Pain ... Cold and Hot CVS …
Matched Products: … Neuro Max Pain and Muscle Relief Gel ... Dermorub Liniment Muscle and Joint ... Flexitol Foot and Knee Pain Relief …

Bumetanide

Bumetanide is a sulfamyl diuretic.
Approved
Matched Synonyms: … 3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Iupac: … 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Categories: … bumetanide and potassium ... Genito Urinary System and Sex Hormones ... bumetanide and potassium-sparing agents ... Gynecological Antiinfectives and Antiseptics ... High-Ceiling Diuretics and Potassium-Sparing Agents …

Suprofen

An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Approved
Withdrawn
Matched Synonyms: … p-2-thenoylhydratropic acid ... (±)-2-(p-(2-thenoyl)phenyl)propionic acid ... 2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid …
Matched Iupac: … 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid …
Matched Description: … An ibuprofen-type anti-inflammatory analgesic and antipyretic. ... It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …

Ethyl hydroxybenzoate

Approved
Experimental
Matched Synonyms: … 4-hydroxybenzoic acid ethyl ester ... p-hydroxybenzoic acid ethyl ester …

Bexarotene

Bexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma.
Approved
Investigational
Matched Synonyms: … 4-[1-(3,5,5,8,8-pentamethyltetralin-2-yl)ethenyl]benzoic acid ... p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid ... 4-[1-(5,6,7,8,-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphtalenyl)ethenyl]benzoic acid …
Matched Iupac: … 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid …
Matched Description: … It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Procaine

A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Synonyms: … 4-aminobenzoic acid 2-diethylaminoethyl ester ... p-Aminobenzoic acid 2-diethylaminoethyl ester …
Matched Description: … A local anesthetic of the ester type that has a slow onset and a short duration of action. ... It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. …
Matched Categories: … Esters of Aminobenzoic Acid ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Benzocaine

Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.
Approved
Investigational
Matched Synonyms: … 4-aminobenzoic acid ethyl ester …
Matched Description: … Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and …
Matched Mixtures name: … Up and up vagicaine ... Sore Throat and Cough ... BENZOCAINE and RESORCINOL …
Matched Categories: … Esters of Aminobenzoic Acid ... Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Sting and Bite ... Bite and Sting relief ... Medicaine Sting and Bite …

Fenofibrate

Fenofibrate is a fibric acid derivative like clofibrate and gemfibrozil. Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.[L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.
Approved
Matched Synonyms: … 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester …
Matched Description: … Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil]. …
Matched Categories: … Fibric Acid Derivatives ... pravastatin and fenofibrate ... simvastatin and fenofibrate ... rosuvastatin and fenofibrate ... pravastatin, ezetimibe and fenofibrate …

Thimerosal

Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent. Developed in 1927, thimerosal has been and is still being used as a preservative in some cosmetics, topical pharmaceuticals, and biological drug products, which includes...
Approved
Matched Synonyms: … ethylmercurithiosalicylic acid sodium salt ... o-(ethylmercurithio)benzoic acid sodium salt …
Matched Description: … This compound is a well-established and widely used antiseptic and antifungal agent. ... pharmaceuticals, and biological drug products, which includes vaccines. ... There has been significant concern regarding its safety and toxicity in the last several decades. …
Matched Categories: … Antiseptics and Disinfectants …

Spironolactone

Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Description: … [A178192] It promotes sodium and water excretion and potassium retention. ... It binds to mineralocorticoid receptors and functions as aldosterone antagonists. ... [L44602] Off-label uses of spironolactone include hirsutism, female pattern hair loss, and adult acne …
Matched Mixtures name: … Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% ... Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% / Tretinoin 0.05% ... Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% / Tretinoin 0.025% …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Lumacaftor

Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Synonyms: … 1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic acid …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … with CF worldwide, is known as F508del-CFTR, or delta-F508 (ΔF508), in which a deletion in the amino acid ... Approved for use by the Food and Drug Administration in July 2015 and by Health Canada in January 2016 ... and trafficking of mature protein to the cell surface. …
Matched Categories: … ivacaftor and lumacaftor …

Benzonatate

Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older than ten years of age. Currently, benzonatate is the only non-narcotic antitussive available as a prescription drug. It works to reduce the activity of cough reflex by desensitizing the tissues of the lungs...
Approved
Matched Synonyms: … p-butylaminobenzoic acid ω-O-methylnonaethyleneglycol ester ... 4-(butylamino)benzoic acid 3,6,9,12,15,18,21,24,27-nonaoxaoctacos-1-yl ester …
Matched Description: … A5790] Because its chemical structure resembles that of the anesthetic agents in the para-amino-benzoic acid ... Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older ... class (such as [procaine] and [tetracaine]), benzonatate exhibits anesthetic or numbing action. …
Matched Categories: … Cough and Cold Preparations …
Displaying drugs 126 - 150 of 850 in total