Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 176 - 200 of 8072 in total

Sinecatechins

Sinecatechins is a botanical drug product for topical use. It is a partially purified fraction of the water extract of green tea leaves from Camellia sinensis, and is a mixture of catechins and other green tea components. Catechins constitute 85 to 95% (by weight) of the total drug substance which...
Approved
Investigational
Nutraceutical
Matched Description: … Catechins constitute 85 to 95% (by weight) of the total drug substance which includes more than 55% of ... It is a partially purified fraction of the water extract of green tea leaves from Camellia sinensis, ... and is a mixture of catechins and other green tea components. …

Eteplirsen

Eteplirsen is a synthetic antisense oligonucleotide and a phosphorodiamidate morpholino oligomer. It consists of a six-membered morpholino ring replacing the five-membered ribofuranosyl rings found in natural DNA and RNA. Duchenne muscular dystrophy is a rare genetic disorder characterized by progressive muscle deterioration and premature death most commonly due to respiratory...
Approved
Investigational
Matched Description: … protein involved in maintaining the structural integrity and function of muscle fibres. ... It consists of a six-membered morpholino ring replacing the five-membered ribofuranosyl rings found in ... [A244930] It is caused by loss-of-function mutations in the DMD gene coding for dystrophin, an essential …

Ganaxolone

Ganaxolone is the 3β-methylated synthetic analog of allopregnanolone, a metabolite of progesterone. Ganaxolone belongs to a class of compounds referred to as neurosteroids. Endogenous neurosteroids, which comprise certain metabolites of progesterone and deoxycorticosterone, bind potently and specifically to GABAA receptors to enhance their inhibitory effects, and are thus known to...
Approved
Investigational
Matched Description: … Ganaxolone is the 3β-methylated synthetic analog of [allopregnanolone],[L41130] a metabolite of [progesterone ... [A3197] Ganaxolone belongs to a class of compounds referred to as neurosteroids. ... [L41130] It was approved under the brand name ZTALMY by the US FDA in March 2022 for the treatment of …

Dicloxacillin

One of the penicillins which is resistant to penicillinase.
Approved
Investigational
Vet approved
Matched Description: … One of the penicillins which is resistant to penicillinase. …
Matched Salts cas: … 343-55-5 …
Matched Categories: … combinations of penicillins …

Cyclopenthiazide

Cyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients . It is a positive allosteric modulator at AMPA-A receptors .
Approved
Matched Categories: … combinations of sulfonamides …

Risdiplam

Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular atrophy (SMA). It increases systemic SMN protein concentrations by improving the efficiency of SMN2 gene transcription. This mechanism of action is similar to its predecessor nusinersen, the biggest difference being their route of administration: nusinersen...
Approved
Investigational
Matched Description: … [onasemnogene abeparvovec], whereas risdiplam offers the ease of oral bioavailability. ... Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular ... [L12615] It increases systemic SMN protein concentrations by improving the efficiency of _SMN2_ gene …
Matched Categories: … Survival of Motor Neuron 2 Splicing Modifier …

Tolevamer

Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Approved
Investigational
Matched Description: … It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …

Raltegravir

Raltegravir is an antiretroviral drug produced by Merck & Co., used to treat HIV infection. It received approval by the U.S. Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase inhibitors, to receive such approval.
Approved
Matched Description: … Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections …

Magnesium

Magnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas, apples, carrots, broccoli, and leafy...
Approved
Experimental
Investigational
Matched Description: … (RDI) of magnesium. ... as food processing and cooking vegetables (which are normally a rich source of magnesium). ... [A19349] Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas …
Matched Mixtures name: … Herbs of Gold B Complex Plus Softgel …

Rituximab

Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences , [FDA label]. It was originally...
Approved
Matched Description: … engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of ... patients with B-cell Non-Hodgkin's Lymphoma (NHL) [L4811], however, has now been approved for a variety of …
Matched Categories: … CD20 (Clusters of Differentiation 20) inhibitors …

Sparfloxacin

Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. DNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, deactivation, and transcription.
Approved
Investigational
Withdrawn
Matched Categories: … Drugs for Treatment of Tuberculosis …

Polythiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)
Approved
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Categories: … combinations of sulfonamides …

Venlafaxine

Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, desvenlafaxine, works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood regulation. Venlafaxine is officially approved to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and...
Approved
Matched Description: … for the management of neuropathic pain (although there is only minimal evidence of efficacy for this ... Its active metabolite, [desvenlafaxine], works by blocking the reuptake of serotonin and norepinephrine ... [L43030] The immediate formulation of the drug, marketed as Effexor, was first approved by the FDA in …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Sulodexide

Sulodexide is a mixture of glycosaminoglycans (GAGs) composed of dermatan sulfate (DS) and fast moving heparin (FMH).
Approved
Investigational
Matched Description: … Sulodexide is a mixture of glycosaminoglycans (GAGs) composed of dermatan sulfate (DS) and fast moving …

Doravirine

Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered in combination with other antiretroviral medicines.[L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg). Doravirine is formally indicated for the treatment of...
Approved
Investigational
Matched Description: … treatments available for the management of HIV-1 infection. ... [L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), ... [L4562] Doravirine is formally indicated for the treatment of HIV-1 infection in adult patients with …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections …

Fluorescein

A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. It has been approved by FDA for use in externally applied drugs...
Approved
Matched Categories: … Diagnostic Uses of Chemicals …

Fingolimod

Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. It was developed by Novartis and initially approved by the FDA in 2010. Fingolimod was also...
Approved
Investigational
Matched Description: … the SARS-CoV-2 virus. ... [L12651] Fingolimod was also studied for the treatment of COVID-19, the disease caused by infection with ... [A176474] Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting …

Oxiconazole

Oxiconazole is an antifungal agent that is commonly found in topical formulations. It is marketed under the brand names Oxistat and Oxistat, and is used in the treatment of various skin infections such as athlete's foot, jock itch and ringworm.
Approved
Matched Description: … It is marketed under the brand names Oxistat and Oxistat, and is used in the treatment of various skin …
Matched Categories: … combinations of imidazole derivatives …

Sulfanilamide

Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.
Approved
Matched Categories: … combinations of sulfonamides …

Remifentanil

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Dextromethorphan

Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]
Approved
Matched Description: … is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of …
Matched Mixtures name: … Hot Lemon Relief for Symptoms Of Cough and Cold ... Hot Liquid Relief for Symptoms Of Cold and Cough ... Hot Lemon Relief for Symptoms Of Cough, Cold and Flu …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Sulfamethoxazole

Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. It is generally given in combination with trimethoprim, which inhibits a sequential step in bacterial folic acid synthesis - these agents work synergistically to block two consecutive steps in the biosynthesis of nucleic acids and...
Approved
Matched Description: … [L11830] In this combination, sulfamethoxazole is useful for the treatment of a variety of bacterial ... infections, including those of the urinary, respiratory, and gastrointestinal tracts. ... acid synthesis - these agents work synergistically to block two consecutive steps in the biosynthesis of …
Matched Categories: … combinations of sulfonamides ... Drugs for Treatment of Tuberculosis …

Turoctocog alfa

Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Description: … from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of ... During secretion, some rFVIII molecules are cleaved at the C-terminal of the heavy chain (HC) at amino ... antibody binding C-terminal to this position is used in the purification process allowing isolation of …

Flibanserin

Flibanserin is the first drug to be approved for hypoactive sexual desire disorder (HSDD) in premenopausal women by the FDA in August 2015. It was originally developed as an antidepressant medication by Boehringer Ingelheim, but showed lack of efficacy in trials and was further developed as a hypoactive sexual disorder...
Approved
Investigational
Matched Description: … It was originally developed as an antidepressant medication by Boehringer Ingelheim, but showed lack of ... Flibanserin's mechanism of action is attributed to its high affinity for 5-HTA1 and 5-HTA2 receptors, ... displaying agonist activity on 5-HTA1 and antagonist on 5-HTA2, resulting in lowering of serotonin in …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Pravastatin

Pravastatin is the 6-alpha-hydroxy acid form of mevastatin. Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug. This drug was developed by Sankyo Co. Ltd.; however, the first approved...
Approved
Matched Description: … Pravastatin is the 6-alpha-hydroxy acid form of [mevastatin]. ... The manufacturing process is followed by the hydrolysis of the lactone group and the biological hydroxylation …
Displaying drugs 176 - 200 of 8072 in total