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Displaying drugs 251 - 275 of 10498 in total
Carfilzomib
Carfilzomib is an injectable antineoplastic agent (IV only). Chemically, it is a modified tetrapeptidyl epoxide and an analog of epoxomicin. It is also a selective proteasome inhibitor. FDA approved carfilzomib in July 2012 for the treatment of adults with relapsed or refractory multiple myeloma as monotherapy or combination therapy.
Approved
Investigational
Matched Iupac: … (2S)-4-methyl-N-[(1S)-1-{[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]carbamoyl}-2-phenylethyl …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET ... Kyprolis 10 mg IV İnfüzyonluk Çözelti Hazırlamak İçin Toz, 1 ADET ... Kyprolis 30 mg IV İnfüzyonluk Çözelti Hazırlamak İçin Toz, 1 ADET …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADET ... Kyprolis 10 mg IV İnfüzyonluk Çözelti Hazırlamak İçin Toz, 1 ADET ... Kyprolis 30 mg IV İnfüzyonluk Çözelti Hazırlamak İçin Toz, 1 ADET …
Pembrolizumab
Pembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation. It contains 32 cysteine residues and the complete folded molecule includes...
Approved
Matched Description: … Pembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. ... It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody ... malignant melanoma by the FDA on September 4, 2014,[L2954] becoming the first approved therapy against PD-1. …
Matched Categories: … PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors ... PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors ... Programmed Death Receptor-1 Blocking Antibody ... Programmed Death Receptor-1-directed Antibody Interactions …
Matched Products: … KEYTRUDA 100 MG/4 ML IV INFUZYONLUK COZELTI İÇEREN FLAKON, 1 ADET …
Matched Categories: … PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors ... PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors ... Programmed Death Receptor-1 Blocking Antibody ... Programmed Death Receptor-1-directed Antibody Interactions …
Matched Products: … KEYTRUDA 100 MG/4 ML IV INFUZYONLUK COZELTI İÇEREN FLAKON, 1 ADET …
Antihemophilic factor, human recombinant
Human recombinant antihemophilic factor (AHF) or Factor VIII, 2332 residues, glycosylated, produced by CHO cells
Approved
Investigational
Matched Products: … ADVATE 3000 IU/5 ML IV ENJEKSIYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET ... ADVATE 250 IU/5 ML IV ENJEKSIYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET ... ADVATE 500 IU/5 ML IV ENJEKSIYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET …
Selumetinib
Activation of the Raf-MEK-ERK signalling pathway is known to be implemented in several types of malignancies; thus, mitogen-activated protein kinase kinase (MEK) inhibitors such as selumetinib are important tools that can target the problematic overactivity of this pathway. Results from clinical trials investigating earlier developed MEK inhibitors were underwhelming. However,...
Approved
Investigational
Matched Iupac: … 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-1,3-benzodiazole-6-carboxamide …
Matched Description: … of Neurofibromatosis type 1 (NF-1) in a limited age group. ... NF-1 is considered rare, with an estimated incidence of 1/3000 individuals. ... [A193611] Currently, the novel MEK 1 / 2 inhibitor, selumetinib, is approved solely for the treatment …
Matched Categories: … Mitogen-Activated Protein Kinase Kinase 1 Inhibitors …
Matched Description: … of Neurofibromatosis type 1 (NF-1) in a limited age group. ... NF-1 is considered rare, with an estimated incidence of 1/3000 individuals. ... [A193611] Currently, the novel MEK 1 / 2 inhibitor, selumetinib, is approved solely for the treatment …
Matched Categories: … Mitogen-Activated Protein Kinase Kinase 1 Inhibitors …
Coagulation Factor IX Human
Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes hemophilia B.
Approved
Matched Mixtures name: … COFACT 250 IU/10 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADET ... COFACT 500 IU/20 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADET …
Matched Products: … HAEMONİNE 1000 IU/10 ML IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON + 1 ÇÖZÜCÜ FLAKON ... HAEMONİNE 500 IU/5 ML IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON + 1 ÇÖZÜCÜ FLAKON ... OCTANİNE F 500 IU/5 ML IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON+1 ÇÖZÜCÜ FLAKON …
Matched Products: … HAEMONİNE 1000 IU/10 ML IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON + 1 ÇÖZÜCÜ FLAKON ... HAEMONİNE 500 IU/5 ML IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON + 1 ÇÖZÜCÜ FLAKON ... OCTANİNE F 500 IU/5 ML IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON+1 ÇÖZÜCÜ FLAKON …
Methotrexate
Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Products: … METHOTREXAT 'EBEWE' PFS 10 MG/1 ML KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... METHOTREXATE 50 MG 1 AMPUL ... DBL METHOTREXATE INJECTION BP 1 g/10 ml …
Belimumab
Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor. BLyS levels are often elevated in immunodeficient and autoimmune disorders, such as systemic lupus erythematosus (SLE).[A251495, L42705] By binding to...
Approved
Matched Products: … BENLYSTA 200 MG / 1 ML ... BENLYSTA SUBCUTÁNEO 200 MG / 1 ML ... BENLYSTA 400 MG IV INFUZYONLUK COZETI HAZIRLAMAK ICIN TOZ ICEREN FLAKON, 1 ADET …
Docetaxel
Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Description: … [A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric …
Matched Products: … DOXİTAX TEC 20 MG/1 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... TADOCEL 20 MG/1 ML IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADET ... ICEREN FLAKON, 1 ADET …
Matched Products: … DOXİTAX TEC 20 MG/1 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... TADOCEL 20 MG/1 ML IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADET ... ICEREN FLAKON, 1 ADET …
Vecuronium
Monoquaternary homolog of pancuronium. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other...
Approved
Investigational
Matched Iupac: … -1H-cyclopenta[a]phenanthren-2-yl]-1-methylpiperidin-1-ium ... 1-[(1R,2S,3aS,3bR,5aS,7S,8S,9aS,9bS,11aS)-1,7-bis(acetyloxy)-9a,11a-dimethyl-8-(piperidin-1-yl)-hexadecahydro …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 FLAKON VE 1 AMPUL ... ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON VE 1 AMPUL ... BLOK-L 4 MG IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 ADET …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 FLAKON VE 1 AMPUL ... ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 FLAKON VE 1 AMPUL ... BLOK-L 4 MG IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ VE ÇÖZÜCÜ, 1 ADET …
Dimetindene
Dimetindene (Fenistil) is an antihistamine/anticholinergic used orally and locally as an antipruritic.
Approved
Investigational
Matched Iupac: … dimethyl(2-{3-[1-(pyridin-2-yl)ethyl]-1H-inden-2-yl}ethyl)amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Dimestil 1 mg/g Gel ... Fenistil 1 mg - Dragees ... Histakut 1 mg/ml Injektionslösung …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Dimestil 1 mg/g Gel ... Fenistil 1 mg - Dragees ... Histakut 1 mg/ml Injektionslösung …
Carboplatin
Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma. Early clinical studies of carboplatin were performed in 1982. Carboplatin was developed as an analog of cisplatin with reduced nephrotoxicity and vomiting.[A230463,A230523]
Carboplatin was granted FDA approval on 3 March 1989.
Approved
Matched Products: … FLAKON, 1 ADET ... FLAKON, 1 ADET ... SOL. 50 MG/5 ML FLAKON, 1 ADET …
Turoctocog alfa
Turoctocog alfa is a recombinant factor VIII (rFVIII) with a truncated B-domain made from the sequence coding for 10 amino acids from the N-terminus and 11 amino acids from the C-terminus of the naturally occurring B-domain. Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any...
Approved
Investigational
Matched Products: … NOVOEİGHT 250 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET ... NOVOEİGHT 500 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET ... NOVOEİGHT 1000 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET …
Hepatitis A Vaccine
Hepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms that include anorexia, nausea, vomiting, and liver failure. Known by several trade names, such as Havrix and Twinrix, the Hepatitis A vaccine has been formulated for immunization against hepatitis A virus (HAV) infection and safely...
Approved
Matched Mixtures name: … TWINRIX ERİŞKİN IM 1 ML SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR …
Matched Products: … VAQTA 50 E/1 ml Injektionssuspension ... VAQTA 50 E/1 ml Injektionssuspension in einer Fertigspritze ... HAVRIX PEDİYATRİK720 EU/0,5 ML IM ENJEKSİYON İÇEREN KULLANIMA HAZIR ENJEKTOR, 1 ADET …
Matched Products: … VAQTA 50 E/1 ml Injektionssuspension ... VAQTA 50 E/1 ml Injektionssuspension in einer Fertigspritze ... HAVRIX PEDİYATRİK720 EU/0,5 ML IM ENJEKSİYON İÇEREN KULLANIMA HAZIR ENJEKTOR, 1 ADET …
Remifentanil
Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sympathetic nervous system tone, and causes respiratory depression and analgesia.
Approved
Matched Iupac: … methyl 1-(3-methoxy-3-oxopropyl)-4-(N-phenylpropanamido)piperidine-4-carboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … REMIFENTANILO 1 MG/ML ... ULTIVA FOR INJECTION 1 mg/vial ... ULTIVA 1 MG ENJEKTABL TOZ İÇEREN FLAKON, 5 ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … REMIFENTANILO 1 MG/ML ... ULTIVA FOR INJECTION 1 mg/vial ... ULTIVA 1 MG ENJEKTABL TOZ İÇEREN FLAKON, 5 ADET …
Alteplase
Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. In the absence of fibrin, the alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and fibrin.[A252330,L43125] Alteplase...
Approved
Investigational
Matched Products: … ACTILYSE 20 MG FLAKON, 1 ADET ... ACTILYSE 10 MG FLAKON, 1 ADET ... ACTILYSE 50 MG FLAKON, 1 ADET …
Baclofen
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Salts cas: … 28311-31-1 …
Matched Products: … BACLOFEN ® 0.05 MG/ 1 ML ... Lioresal intrathekal 0,05 mg/1 ml - Ampullen ... BAXEN 10 MG/20 ML İNTRATEKAL İNFÜZYONLUK ÇÖZELTİ, 1 ADET …
Matched Products: … BACLOFEN ® 0.05 MG/ 1 ML ... Lioresal intrathekal 0,05 mg/1 ml - Ampullen ... BAXEN 10 MG/20 ML İNTRATEKAL İNFÜZYONLUK ÇÖZELTİ, 1 ADET …
Rituximab
Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light and heavy-chain variable region sequences and human constant region sequences , [FDA label]. It was originally...
Approved
Matched Products: … İNFÜZYONLUK ÇÖZELTİ İÇİN KONSANTRE, 1 FLAKON ... İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET ... İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET …
Methantheline
Methantheline is a synthetic antispasmodic. Antispasmodics are used to relieve cramps or spasms of the stomach, intestines, and bladder. Methantheline is used to treat intestine or stomach ulcers (peptic ulcer disease), intestine problems (irritable bowel syndrome), pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, or urinary problems (reflex neurogenic bladder in children).
Approved
Investigational
Fluorouracil
A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Approved
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Fluoroplex Cream 1% ... ICEREN FLAKON, 1 ADET ... ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …
Matched Products: … Fluoroplex Cream 1% ... ICEREN FLAKON, 1 ADET ... ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …
Metamizole
Metamizole (dipyrone) is a pyrazolone derivative that belongs to the group of nonacid nonopioids. It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability. Metamizole was formerly marketed in the US as Dimethone tablets and injection, Protemp oral liquid, and other drug products, and was withdrawn due to...
Approved
Investigational
Withdrawn
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … SEBON 1 G AMPUL, 5 ADET ... SEBON 1 G AMPUL, 10 ADET ... NOGESIC 2 ML 1 GR 10 AMPUL …
Matched Products: … SEBON 1 G AMPUL, 5 ADET ... SEBON 1 G AMPUL, 10 ADET ... NOGESIC 2 ML 1 GR 10 AMPUL …
Pitavastatin
Pitavastatin, also known as the brand name product Livalo, is a lipid-lowering drug belonging to the statin class of medications. By inhibiting the endogenous production of cholesterol within the liver, statins lower abnormal cholesterol and lipid levels and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively...
Approved
Matched Description: … cardiovascular events (heart attack, stroke, coronary revascularization, and coronary death) for every 1 …
Matched Products: … Trolise 1 mg Filmtabletten ... PITAMIN 1 MG EFERVESAN TABLET, 30 ADET ... PITAMIN 1 MG EFERVESAN TABLET, 90 ADET …
Matched Products: … Trolise 1 mg Filmtabletten ... PITAMIN 1 MG EFERVESAN TABLET, 30 ADET ... PITAMIN 1 MG EFERVESAN TABLET, 90 ADET …
Icatibant
Icatibant is a synthetic decapeptide with 5 nonproteinogenic amino acid antagonist targeting the B2 receptors with a similar affinity to bradykinin. It is resistant to bradykinin-cleaving enzyme degradation and has a potency of 2-3 times higher than earlier B2 receptors antagonists, thus representing a new class of medication.[A4017,A263041] It was...
Approved
Investigational
Matched Description: … positive results obtained from 3 double-blind, randomized, controlled clinical trials known as FAST 1, …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... İKTU 30 MG/3 ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Matched Products: … ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... İKTU 30 MG/3 ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Methylprednisolone aceponate
Approved
Vet approved
Matched Iupac: … ,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl propanoate ... (1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1-[2-(acetyloxy)acetyl]-10-hydroxy-5,9a,11a-trimethyl-7-oxo-1H,2H,3H …
Matched Products: … EXENATE %0,1 KREM ,1 TÜP-30G ... EXENATE %0,1 LOSYON ,1 TÜP-50G ... EXENATE %0,1 MERHEM, 1 TÜP-30G …
Matched Products: … EXENATE %0,1 KREM ,1 TÜP-30G ... EXENATE %0,1 LOSYON ,1 TÜP-50G ... EXENATE %0,1 MERHEM, 1 TÜP-30G …
Hypromellose
Hypromellose, or hydroxypropyl methylcellulose (HPMC) , is a semisynthetic, inert, and viscoelastic polymer that forms a colloid solution when dissolved in water. It acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of granulation and in modified release formulations . It...
Approved
Matched Mixtures name: … TEARS NATURALE II 1 MG/ML + 3 MG/ML GÖZ DAMLASI …
Matched Products: … Alcon Tears 1% ... Sandoz Eyelube 1% ... Mc Methylcellulose Solution 1% …
Matched Products: … Alcon Tears 1% ... Sandoz Eyelube 1% ... Mc Methylcellulose Solution 1% …
Cinchocaine
A local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)
Approved
Vet approved
Matched Salts cas: … 61-12-1 …
Matched Mixtures name: … Dibucaine HCl 0.5% / Lidocaine 15% / Phenylephrine HCl 1% / Prilocaine 5% …
Matched Products: … Nupercainal Anesthetic Ointment 1% ... Dibucaine Topical Anesthetic 1% Hemorrhoidal …
Matched Mixtures name: … Dibucaine HCl 0.5% / Lidocaine 15% / Phenylephrine HCl 1% / Prilocaine 5% …
Matched Products: … Nupercainal Anesthetic Ointment 1% ... Dibucaine Topical Anesthetic 1% Hemorrhoidal …
Displaying drugs 251 - 275 of 10498 in total