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Displaying drugs 26 - 50 of 1701 in total

Finerenone

Finerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart attacks, and hospitalization due to heart failure in adults with chronic kidney disease associated with type II diabetes mellitus.[A236519,L34739] Patients with kidney...
Approved
Investigational
Matched Products: … KERENDİA 10 MG FİLM KAPLI TABLET, 28 ADET ... KERENDİA 20 MG FİLM KAPLI TABLET, 28 ADET …

Sertraline

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before...
Approved
Matched Salts cas: … 79559-97-0 …
Matched Products: … LUSTRAL 50 MG TABLET, 28 ADET ... MISOL 50 MG FILM TABLET, 28 ADET ... LUSTEC 50 MG FILM TABLET, 28 ADET …

Bosutinib

Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.[A6902,A261796,A261801] The first BCR-ABL inhibitor,...
Approved
Matched Products: … BOSULİF 500 MG FİLM KAPLI TABLET, 28 ADET ... BOSULİF 100 MG FİLM KAPLI TABLET, 28 ADET …

Daclatasvir

Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection. It is marketed under the name DAKLINZA and is contained in daily oral tablets as the hydrochloride salt form . Hepatitis C is an infectious liver disease...
Approved
Investigational
Matched Products: … DAKLINZA 30 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 28 ADET ... DAKLINZA 60 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 28 ADET …

Glatiramer

Glatiramer acetate is a mix of synthetic polypeptides that includes L-glutamic acid, L-alanine, L-tyrosine, and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. Since glatiramer acetate is a heterogeneous drug, there is limited information about its physicochemical properties. Originally, glatiramer acetate was designed as a...
Approved
Investigational
Matched Products: … GLIA 20 MG/ML ENJEKSIYONLUK ÇÖZELTI, KULLANIMA HAZIR DOLU ENJEKTÖR, 28 ADET ... ROGRESİF 20 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 28 ADET ... COPAXONE 20 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR DOLU ENJEKTÖR, 28 ENJEKTÖR …

Prucalopride

Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties. The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. Prucalopride was developed by Shire Development LLC...
Approved
Matched Products: … RESOLOR 1MG FILM KAPLI TABLET, TABLET, 28 ADET ... RESOLOR 2MG FILM KAPLI TABLET, TABLET, 28 ADET …

Tolvaptan

Tolvaptan is used to treat low blood sodium levels (hyponatremia) associated with various conditions like congestive heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormones (SIADH). FDA approved on May 19, 2009.
Approved
Matched Products: … JİNARC 15 MG TABLET, 28 ADET ... JİNARC 30 MG TABLET, 28 ADET …

Letermovir

Letermovir recieved approval from the FDA on November 8th, 2017 for use in prophylaxis of cytomegalovirus (CMV) infection in allogeneic hematopoietic stem cell transplant patients. It is the first of a new class of CMV anti-infectives called DNA terminase complex inhibitors. Letermovir has recieved both priority and orphan drug status...
Approved
Investigational
Matched Products: … PREVYMİS 240 MG FİLM KAPLI TABLET, 28 ADET ... PREVYMİS 480 MG FİLM KAPLI TABLET, 28 ADET …

Tadalafil

Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. In contrast to other PDE5 inhibitors...
Approved
Investigational
Matched Iupac: … (2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca …
Matched Products: … REKFİL 5 MG TABLET, 28 ADET ... LONGIVO 5 MG TABLET, 28 ADET ... LONGIVO 2.5 MG TABLET, 28 ADET …

Bicalutamide

Bicalutamide is an oral non-steroidal anti-androgen for prostate cancer. It is comprised of a racemic mixture that is a 50:50 composition of the (R)-bicalutamide and (S)-bicalutamide enantionmers. Bicalutamide binds to the androgen receptor.
Approved
Matched Products: … CASODEX 50 MG TABLET, 28 ADET ... CASODEX 150 MG TABLET, 28 ADET ... PROCALUT 50 MG FILM TABLET, 28 ADET …

Alendronic acid

Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Salts cas: … 129318-43-0 …
Matched Mixtures name: … OSTEOCAL 12MG/1000MG/880IU EFERVESAN TABLET, 28 ADET …
Matched Products: … LENDO 10 MG TABLET, 28 ADET ... ADROMAX 5 MG TABLET,28 ADET ... ADROMAX 10 MG TABLET,28 ADET …

Dexlansoprazole

Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated with gastroesophageal reflux disease (GERD) and erosive esophagitis. Dexlansoprazole is the R-enantiomer of DB00448, which is composed of a racemic mixture of the R- and S-enantiomers. Compared to the older generation of PPIs (which includes...
Approved
Investigational
Matched Products: … DEXAPOL 30 MG ENTERIK KAPLI MIKROTABLET ICEREN KAPSUL, 28 ADET ... DEXAPOL 60 MG ENTERIK KAPLI MIKROTABLET ICEREN KAPSUL, 28 ADET …

Fesoterodine

Fesoterodine is an antimuscarinic prodrug for the treatment of overactive bladder syndrome.
Approved
Matched Products: … FOSETAZ 4 MG UZATILMIŞ SALIMLI FİLM KAPLI TABLET, 28 ADET ... FOSETAZ 8 MG UZATILMIŞ SALIMLI FİLM KAPLI TABLET, 28 ADET …

Itraconazole

First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used to treat a variety of infections. It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each possessing three chiral centers. Itraconazole was first approved in the US in 1992 and...
Approved
Investigational
Matched Products: … CANDİSTAT 100 MG SERT KAPSÜL, 28 ADET ... SPOREX 100 MG MIKROPELLET KAPSUL, 28 ADET ... ITRAXYL 100 MG MIKROPELLET KAPSUL, 28 ADET …

Carvedilol

Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker.[L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension.[L7889,L7892] The dual action of carvedilol is advantageous in combination therapies as...
Approved
Investigational
Matched Products: … ARLEC 25 MG TABLET, 28 ADET ... ARLEC 12.5 MG TABLET, 28 ADET ... ARLEC 6,25 MG TABLET, 28 ADET …

Milnacipran

Milnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) and like many agents in this category was originally developed for and continues to be approved and indicated for the treatment of depression [F3928, F3934, A175786, A175951]. Furthermore, in 2009 the US FDA approved milnacipran for the additional indication of...
Approved
Investigational
Matched Products: … IXEL 25 MG KAPSUL, 28 ADET …

Metoprolol

Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date,...
Approved
Investigational
Matched Salts cas: … 119637-66-0 …
Matched Products: … METOPROLOL ABZ 0.K. 50MG ... METOPROLOL ABZ 0.K. 100MG ... METOPROLOL ABZ 0.K. 200MG …

Nalmefene

Nalmefene, a 6-methylene analogue of naltrexone, is an opioid receptor antagonist. It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. In Europe, nalmefene oral tablets are used to reduce alcohol consumption in adults with alcohol dependence. Nalmefene...
Approved
Investigational
Withdrawn
Matched Iupac: … (1S,5R,13S,17S)-4-(cyclopropylmethyl)-14-methylidene-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0 …
Matched Salts cas: … 58895-64-0 …
Matched Products: … SELINCRO 18MG FILM KAPLI TABLET ,TABLET, 28 ADET …

Asfotase alfa

Asfotase alfa is a first-in-class bone-targeted enzyme replacement therapy designed to address the underlying cause of hypophosphatasia (HPP)—deficient alkaline phosphatase (ALP). Hypophosphatasia is almost always fatal when severe skeletal disease is obvious at birth. By replacing deficient ALP, treatment with Asfotase Alfa aims to improve the elevated enzyme substrate levels...
Approved
Investigational
Matched Description: … Agency of Japan (PMDA) on July 3, 2015, then approved by the European Medicine Agency (EMA) on August 28 …
Matched Products: … STRENSİQ 28 MG/0.7 ML ENJEKSİYONLUK ÇÖZELTİ, 12 ADET …

Ropinirole

Ropinirole, also known as ReQuip, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], . It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. In 2005, it was the first...
Approved
Investigational
Matched Products: … PARGUIP XL 2 MG UZATILMIŞ SALIMLI TABLET, 28 ADET ... PARGUIP XL 4 MG UZATILMIŞ SALIMLI TABLET, 28 ADET ... PARGUIP XL 8 MG UZATILMIŞ SALIMLI TABLET, 28 ADET …

Rofecoxib

Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. Rofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 )...
Approved
Investigational
Withdrawn
Matched Products: … REOX 12.5 MG TABLET, 28 ADET ... REOX 25 MG FORT TABLET, 28 ADET …

Prasugrel

Prasugrel, a thienopyridine derivative, is a platelet activation and aggregation inhibitor structurally and pharmacologically related to clopidogrel and ticlopidine. Similar to clopidogrel, prasugrel is a prodrug that requires enzymatic transformation in the liver to its active metabolite, R-138727. R-138727 irreversibly binds to P2Y12 type ADP receptors on platelets thus preventing...
Approved
Matched Salts cas: … 389574-19-0 …
Matched Products: … EFFIENT 10 MG FILM KAPLI TABLET, 28 ADET ... SUGVİDA 10 MG FİLM KAPLI TABLET, 28 ADET …

Lisinopril

Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a...
Approved
Investigational
Matched Mixtures name: … RILACE PLUS 20 MG/25 MG TABLET, 28 TABLET ... RILACE PLUS 20 MG/12.5 MG TABLET, 28 TABLET …
Matched Products: … APRIL-ACE 5 MG TABLET, 28 ADET ... APRIL-ACE 20 MG TABLET, 28 ADET ... RILACE 5 MG TABLET, 28 TABLET …

Alpelisib

Alpelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potent antitumor activity. It works by selectively inhibiting class I PI3K p110α , which is the catalytic subunit of PI3K, a lipid kinase that plays a role in various biological processes, including proliferation, survival, differentiation, and metabolism. Alpelisib was designed to target...
Approved
Investigational
Matched Products: … PİMREVA 200 MG FİLM KAPLI TABLET, 28 ADET …

Sodium bicarbonate

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Mixtures name: … ESOVIP 20/1680 MG TOZ İÇEREN SAŞE, 28 ADET ... RASOFORCE 20/1680 MG TOZ İÇEREN SAŞE, 28 SAŞE ... Prismasol 0 …
Displaying drugs 26 - 50 of 1701 in total