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Displaying drugs 76 - 100 of 12599 in total

Amlodipine

Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Synonyms: … (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate ... 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate …
Matched Iupac: … 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Salts cas: … 88150-47-4 ... 652969-01-2 …
Matched Mixtures name: … CARDIK®3 160/10/12.5 ... CARDIK®3 160/10/12.5 ... CARDIK ® 3 160/5/12.5 …
Matched Products: … AMLESSA TABLETS 4 mg/ 5mg ... AMLESSA TABLETS 4 mg/ 10mg …

Sulfamerazine

A sulfanilamide that is used as an antibacterial agent.
Approved
Vet approved
Matched Synonyms: … 2-(4-Aminobenzenesulfonamido)-4-methylpyrimidine ... 2-Sulfa-4-methylpyrimidine ... 4-Amino-N-(4-methyl-2-pyrimidinyl)-benzenesulfonamide …
Matched Iupac: … 4-amino-N-(4-methylpyrimidin-2-yl)benzene-1-sulfonamide …
Matched Salts cas: … 127-58-2 …

Cinchocaine

A local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)
Approved
Vet approved
Matched Synonyms: … 2-butoxy-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide ... 2-Butoxy-quinoline-4-carboxylic acid (2-diethylamino-ethyl)-amide ... 2-butoxyquinoline-4-carboxylic acid diethylaminoethylamide …
Matched Iupac: … 2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Fluphenazine

A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Approved
Matched Synonyms: … 2-(4-(3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanol ... 1-(2-hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine ... 4-(3-(2-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol …
Matched Iupac: … 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … Fluphenazine 2 Tab 2mg ... PROLİXİN DECANOATE 25 MG/ML I.M UZATILMIŞ SALIMLI ENJEKSİYONLUK ÇÖZELTİ, 3 ADET …

Octisalate

Also known as Ethylhexyl Salicylate. Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen. Salicylates are weak UVB absorbers and they are generally used in combination with other...
Approved
Investigational
Matched Synonyms: … 2-Ethylhexyl 2-hydroxybenzoate ... 2-Ethylhexyl salicylate …
Matched Iupac: … 2-ethylhexyl 2-hydroxybenzoate …
Matched Description: … It is an ester of salicylic acid and 2-ethylhexanol. …
Matched Mixtures name: … OP Dark Tanning Gel 4 ... SRB 3 Lighting White Sun ... NO-AD Dark Tanning SPF 4 …

Dexlansoprazole

Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated with gastroesophageal reflux disease (GERD) and erosive esophagitis. Dexlansoprazole is the R-enantiomer of DB00448, which is composed of a racemic mixture of the R- and S-enantiomers. Compared to the older generation of PPIs (which includes...
Approved
Investigational
Matched Synonyms: … (+)-2-((R)-((3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)PYRIDIN-2-YL)METHYL)SULFINYL)-1H-BENZIMIDAZOLE ... 1H-BENZIMIDAZOLE, 2-((R)-((3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)-2-PYRIDINYL)METHYL)SULFINYL)- ... 2-((R)-((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole …
Matched Iupac: … 2-[(R)-[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl]-1H-1,3-benzodiazole …
Matched Categories: … 2-Pyridinylmethylsulfinylbenzimidazoles ... Heterocyclic Compounds, 2-Ring …

Pralidoxime

Pralidoxime is an antidote to organophosphate pesticides and chemicals. Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible inactivation of the enzyme. If given within 24 hours,after organophosphate exposure, pralidoxime reactivates the enzyme cholinesterase by cleaving the phosphate-ester bond formed between the organophosphate and acetylcholinesterase.
Approved
Vet approved
Matched Synonyms: … 2-PAM …
Matched Iupac: … 2-[(E)-(hydroxyimino)methyl]-1-methylpyridin-1-ium …
Matched Products: … CONTRATHION® 2% ... CONTRATHION % 2 FLAKON, 10 ADET …

Procaine

A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Synonyms: … 4-aminobenzoic acid 2-diethylaminoethyl ester ... β-(diethylamino)ethyl 4-aminobenzoate ... 2-Diethylaminoethyl p-aminobenzoate …
Matched Iupac: … 2-(diethylamino)ethyl 4-aminobenzoate …
Matched Salts cas: … 6192-92-3 …
Matched Products: … Novocain Liq 2% ... PROCANOL LOTION 2% ... VERSENIKCAINA® 2% …

Lotilaner

Lotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals.[A260746, L47556] Lotilaner consists of two enantiomers: the S-enantiomer is active in vivo, while the R-enantiomer is...
Approved
Vet approved
Matched Synonyms: … )-3-methyl-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)- ... )-4,5-dihydro-1,2-oxazol-3-yl)thiophene-2-carboxamide ... 3-methyi-n-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-5-((55)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl …
Matched Iupac: … 2-({3-methyl-5-[(5S)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl]thiophen ... -2-yl}formamido)-N-(2,2,2-trifluoroethyl)acetamide …

Trolamine

Trolamine, which is also referred to as triethanolamine (TEA), is a tertiary amine and a triol. It is a bifunctional compound that exhibits both properties of alcohols and amines. Trolamine contains small amounts of diethanolamine and ethanolamine and may also act as an antioxidant against the auto-oxidation of animal and...
Approved
Matched Synonyms: … nitrilo-2,2',2''-triethanol ... tris(2-hydroxyethyl)amine ... 2,2',2''-nitrilotris(ethanol) …
Matched Iupac: … 2-[bis(2-hydroxyethyl)amino]ethan-1-ol …

Propafenone

An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.
Approved
Matched Synonyms: … 1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone ... 2-(2'-hydroxy-3'-propylaminopropoxy)-ω-phenylpropiophenone …
Matched Iupac: … 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one …

Lormetazepam

Lormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia . It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.
Approved
Matched Synonyms: … 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one ... 7-Chloro-1,3-dihydro-5-(o-chlorophenyl)-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one …
Matched Iupac: … 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … NOCTAMID 2 TABLETTEN ... Sedalor 2 mg/10 ml Injektions-/Infusionslösung …

Diclofenamide

A carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
Approved
Investigational
Matched Synonyms: … 3,4-dichloro-5-sulfamylbenzenesulfonamide …

Cefotiam

One of the cephalosporins that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
Approved
Investigational
Matched Synonyms: … (6R,7R)-7-[2-(2-Amino-thiazol-4-yl)-acetylamino]-3-[1-(2-dimethylamino-ethyl)-1H-tetrazol-5-ylsulfanylmethyl ... ]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … (6R,7R)-7-[2-(2-amino-1,3-thiazol-4-yl)acetamido]-3-[({1-[2-(dimethylamino)ethyl]-1H-1,2,3,4-tetrazol ... -5-yl}sulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Zavegepant

Zavegepant (BHV-3500) is a calcitonin gene-related peptide (CGRP) receptor antagonist. CGRP is released from sensory nerves and acts as a strong vasodilator, and thanks to these properties, it is involved in pain pathways. CGRP receptors are expressed in the central and peripheral nervous system; however, CGRP does not cross the...
Approved
Investigational
Matched Synonyms: … 1-piperidinecarboxamide, 4-(1,2-dihydro-2-oxo-3-quinolinyl)-n-((1r)-1-((7-methyl-1h-indazol-5-yl)methyl ... )-2-(4-(1-methyl-4-piperidinyl)-1-piperazinyl)-2-oxoethyl)- …
Matched Iupac: … N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4 ... -(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Experimental Unapproved Treatments for COVID-19 …

Coenzyme M

Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.
Approved
Investigational
Matched Synonyms: … 2-Mercaptoethane ... 2-Mercaptoethanesulfonate ... 2-mercaptoethylsulfonate …
Matched Iupac: … 2-sulfanylethane-1-sulfonic acid …
Matched Salts cas: … 19767-45-4 …
Matched Products: … UROPROT® 400 MG/4 ML SOLUCION INYECTABLE ... UROMITEXAN 400 MG/4 ML ENJEKSİYONLUK ÇÖZELTİ, 15 ADET ... UROMITEXAN 400 MG/4 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 15 ADET …

Pyrithione

Pyrithione zinc, or zinc pyrithione or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers. In the crystalline state, it exists as a centrosymmetric dimer. Due to its dynamic fungistatic and bacteriostatic properties, pyrithione zinc is used to treat...
Approved
Matched Synonyms: … 2-pyridinethiol 1-oxide …
Matched Iupac: … 2-sulfanylpyridin-1-ium-1-olate …
Matched Description: … or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+ …
Matched Salts cas: … 3811-73-2 …
Matched Products: … Head and Shoulders 3 In 1 Men ... Australian Gold Metro 365 Medicated Leave-In Treatment Step 3 ... Axe 2 in 1 Armor AntiDandruff 2 in 1 …

Salicylic acid

A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Approved
Investigational
Vet approved
Matched Synonyms: … 2-Carboxyphenol ... 2-Hydroxybenzoic acid …
Matched Iupac: … 2-hydroxybenzoic acid …
Matched Mixtures name: … denovo 3 H ... Ketoconazole 2% / Salicylic Acid 2% ... NW SULPHUR 2%W/W AND SALICYLIC ACID 2%W/W CREAM …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Products: … DHS SAL 4 oz. ... Killa Extra Strength 4 pack ... PUR 4-in-1 Correcting Primer …

Ganciclovir

An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Approved
Investigational
Matched Synonyms: … 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-1H-purin-6(9H)-one ... 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-9H-purin-6-ol ... 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-3H-purin-6(9H)-one …
Matched Iupac: … 2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-1H-purin-6-one …
Matched Categories: … MATE 2 Substrates ... Heterocyclic Compounds, 2-Ring …

Tofersen

Tofersen is under an intrathecally administered antisense oligonucleotide targeting the mutated SOD1 gene that causes amyotrophic lateral sclerosis (ALS). Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented.[A259028,A259033] Tofersen was granted accelerated approval from the FDA...
Approved
Investigational
Matched Synonyms: … DNA, D((2'-O-(2-METHOXYETHYL))M5RC-SP-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-SP-(2'-O-(2 ... (2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))R ... -METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))RA-SP-T-SP-A-SP-M5C-SP-A-SP-T-SP-T-SP-T-SP-M5C-SP-T-SP-A-SP- …
Matched Description: … [L46108] Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more ... Continual FDA approval is contingent on clinical benefits from ongoing trials, particularly the Phase 3 …

Rosiglitazone

Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl). Like other thiazolidinediones, the mechanism of action of rosiglitazone is by activation of the intracellular receptor...
Approved
Investigational
Matched Synonyms: … (RS)-5-{4-[2-(Methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedion ... (±)-5-[p-[2-(methyl-2-pyridylamino)ethoxy]benzyl]-2,4-thiazolidinedione …
Matched Iupac: … 5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione …

Ceritinib

Ceritinib is used for the treatment of adults with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) following failure (secondary to resistance or intolerance) of prior crizotinib therapy. About 4% of patients with NSCLC have a chromosomal rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like...
Approved
Matched Synonyms: … N-{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl} ... propane-2-sulfonamide …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … About 4% of patients with NSCLC have a chromosomal rearrangement that generates a fusion gene between ... EML4 (echinoderm microtubule-associated protein-like 4) and ALK (anaplastic lymphoma kinase), which …

Synthetic camphor

Approved
Experimental
Matched Synonyms: … 2-bornanone ... 2-camphanone ... 1,7,7-trimethylbicyclo(2.2.1)heptan-2-one …
Matched Iupac: … 1,7,7-trimethylbicyclo[2.2.1]heptan-2-one …
Matched Mixtures name: … My Omega 3 Rub ... Menthol 10 percent plus Camphor 4 percent ... Omega 3 Targeted Relief …

Tamsulosin

Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common.[Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy.[Label] Antagonism of these receptors leads to relaxation of smooth muscle in...
Approved
Investigational
Matched Synonyms: … (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide …
Matched Iupac: … 5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzene-1-sulfonamide …

Dihydrostreptomycin

Dihydrostreptomycin is an aminoglycoside antibiotic. In humans, the use of dihydrostreptomycin has been associated with ototoxicity. The FDA withdrew its approval for the use of all drug products containing dihydrostreptomycin sulfate.
Approved
Investigational
Vet approved
Withdrawn
Matched Synonyms: … N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-a-L-glucopyranosyl]-3-C-(hydroxymethyl ... N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-α-L-glucopyranosyl]-3-C-(hydroxymethyl ... N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-(hydroxymethyl …
Matched Iupac: … )-3-(methylamino)oxan-2-yl]oxy}-4-hydroxy-4-(hydroxymethyl)-5-methyloxolan-2-yl]oxy}-2,4,5-trihydroxycyclohexyl ... N-[(1S,2R,3R,4S,5R,6R)-3-carbamimidamido-6-{[(2R,3R,4R,5S)-3-{[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl …
Displaying drugs 76 - 100 of 12599 in total