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Displaying drugs 76 - 100 of 14929 in total
Vigabatrin is an analog of gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and infantile spasms. It irreversibly inhibits the enzyme responsible for GABA metabolism, thereby increasing levels of circulating GABA. Although administered as a racemic mixture, only the...
Approved
Matched Synonyms: … 4-Amino-5-hexenoic acid ... Vinyl gamma-aminobutyric acid ... gamma-Vinyl-gamma-aminobutyric acid
Matched Iupac: … 4-aminohex-5-enoic acid
Matched Description: … Vigabatrin is an analog of gamma-aminobutyric acid ([GABA]), the main inhibitory neurotransmitter in ... the central nervous system, used in the treatment of refractory seizures and infantile spasms. ... [A202037] It was first introduced as an antiepileptic agent in the United Kingdom in 1989 and was …
Matched Categories: … Fatty Acid Derivatives …
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Synonyms: … 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid ... 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
Matched Iupac: … 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
Matched Description: … [A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration …
Matched Mixtures name: … Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone ... Ciprofloxacin and Dexamethasone …
Matched Categories: … ciprofloxacin and tinidazole ... ciprofloxacin and ornidazole ... ciprofloxacin and metronidazole ... Ophthalmological and Otological Preparations ... Drug-Related Side Effects and Adverse Reactions …
Matched Products: … Ciprofloxacin and Dextrose ... CILOXAN STERILE OPHTHALMIC AND OTIC SOLUTION 0.3% …
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Approved
Investigational
Matched Synonyms: … Phenobarbituric Acid ... Phenylethylbarbituric Acid ... 5-Ethyl-5-phenylbarbituric acid
Matched Description: … It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents ... A barbituric acid derivative that acts as a nonselective central nervous system depressant. …
Matched Mixtures name: … Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Categories: … Excitatory Amino Acid Agents ... Excitatory Amino Acid Antagonists ... Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars …
An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit...
Approved
Nutraceutical
Withdrawn
Matched Synonyms: … (S)-α-amino-1H-indole-3-propanoic acid ... (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid ... (S)-alpha-Amino-beta-(3-indolyl)-propionic acid
Matched Iupac: … (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid
Matched Description: … An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults ... It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Travasol Amino Acid Inj 8.5% …
Matched Categories: … Amino Acids, Peptides, and Proteins …
A fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)
Approved
Investigational
Matched Synonyms: … 2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester ... alpha-(p-Chlorophenoxy)isobutyric acid, ethyl ester ... 2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl ester …
Matched Description: … A fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia …
Matched Categories: … Clofibric Acid
Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.
Approved
Matched Synonyms: … Dipotassium acid phosphate ... Phosphoric acid, dipotassium salt ... Phosphoric acid, potassium salt (1:2) …
Matched Description: … as a source of phosphorus and potassium as well as a buffering agent. ... Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive …
Matched Mixtures name: … Ionosol B and Dextrose ... Travasol Amino Acid Inj 8.5% ... Travasol Amino Acid Inj 5.5% …
The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets from the market on August 5, 1982.
Approved
Withdrawn
Matched Synonyms: … (1)-2-(4-Chlorophenyl)benzoxazole-5-propionic acid ... 2-(4-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid ... 2-(p-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid
Matched Iupac: … 2-[2-(4-chlorophenyl)-1,3-benzoxazol-5-yl]propanoic acid
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Approved
Withdrawn
Matched Synonyms: … p-2-thenoylhydratropic acid ... (±)-2-(p-(2-thenoyl)phenyl)propionic acid ... 2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid
Matched Iupac: … 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid
Matched Description: … An ibuprofen-type anti-inflammatory analgesic and antipyretic. ... It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Ceftobiprole medocaril is a prodrug of ceftobiprole, a fifth-generation semisynthetic cephalosporin antibacterial. Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative bacteria, including antibiotic-resistant strains of Staphylcoccus aureus (methicillin-resistant Staphylococcus aureus; MRSA). The EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a negative opinion...
Approved
Experimental
Investigational
Matched Synonyms: … Ceftobiprole medocaril free acid
Matched Iupac: … -2-oxo-[1,3'-bipyrrolidin]-3-ylidene]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Description: … infections and bacteremia in April 2024. ... Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative ... was subsequently approved in the United States with additional indications for skin and skin structure …
Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief...
Approved
Investigational
Matched Synonyms: … Glycerol, nitric acid triester …
Matched Description: … [A180166,A180172] Its use as a treatment for angina dates back to 1879 and is still used to treat and ... [A249970] Nitroglycerin causes vasodilation in both arteries and veins. ... Nitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent …
Matched Mixtures name: … NITROGLICERINA 0.1 MG/ML EN DEXTROSA 5% SOLUCION INYECTABLE …
Matched Categories: … Nitrates and Nitrites ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … NITROGLICERINA EN DEXTROSA AL 5% 50MG/250ML …
Icosapent ethyl or ethyl eicosapentaenoic acid is a synthetic derivative of the omega-3 fatty acid eicosapentaenoic acid (EPA). It is used as an adjunct therapy for severe hypertriglyceridemia (TG levels > 500 mg/dL) and to reduce the risk of cardiovascular events in certain patients with elevated triglycerides. FDA approved on...
Approved
Investigational
Nutraceutical
Matched Synonyms: … ethyl-eicosapentaenoic acid ... Timnodonic acid ethyl ester ... Eicosapentaenoic acid ethyl ester …
Matched Description: … acid (EPA). ... It is used as an adjunct therapy for severe hypertriglyceridemia (TG levels > 500 mg/dL) and to reduce ... Icosapent ethyl or ethyl eicosapentaenoic acid is a synthetic derivative of the omega-3 fatty acid eicosapentaenoic …
Approved
Experimental
Matched Synonyms: … 4-hydroxybenzoic acid ethyl ester ... p-hydroxybenzoic acid ethyl ester …
A cephalorsporin antibiotic that is no longer commonly used.
Approved
Matched Synonyms: … Cephaoglycin acid ... 7-(2-D-alpha-Aminophenylacetamido)cephalosporanic acid ... 7-(D-alpha-Aminophenyl-acetamido)cephalosporanic acid
Matched Iupac: … acetyloxy)methyl]-7-[(2R)-2-amino-2-phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Synonyms: … 2-amino-3-(4-bromobenzoyl)benzeneacetic acid ... [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid
Matched Iupac: … 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record …
A lignan found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and...
Approved
Matched Synonyms: … Podophyllinic acid lactone …
Matched Description: … and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives. ... It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. ... It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts …
Matched Categories: … Skin and Mucous Membrane Agents …
Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … .)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM COPIES …
Matched Description: … of somatrogon and allows its once-weekly dosing. ... adolescence and regulating metabolic function in adulthood. ... by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Somatropin and Somatropin Agonists ... Anterior Pituitary Lobe Hormones and Analogues …
Bexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma.
Approved
Investigational
Matched Synonyms: … 4-[1-(3,5,5,8,8-pentamethyltetralin-2-yl)ethenyl]benzoic acid ... p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid ... 4-[1-(5,6,7,8,-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphtalenyl)ethenyl]benzoic acid
Matched Iupac: … 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid
Matched Description: … It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism.
Approved
Investigational
Matched Synonyms: … Thrombomodulin (human 498-amino acid fragment) …
Matched Description: … Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). ... It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential ... treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in the diet. Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia. It can also be taken by mouth but is not recommended by injection into a muscle. Calcium Gluconate Injection,...
Approved
Vet approved
Matched Synonyms: … D-gluconic acid, calcium salt (2:1) …
Matched Description: … Hydrochloric acid and/or sodium hydroxide may have been added for pH adjustment (6.0 to 8.2). ... Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in ... Calcium saccharate provides 6% of the total calcium and stabilizes the supersaturated solution of calcium …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … HYDROFLUORIC ACID ANTIDOTE GEL 2.5% w/w …
Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Investigational
Vet approved
Matched Description: … through aerobic or anaerobic respiration and fermentation. ... Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and ... L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. …
Matched Mixtures name: … HD-8A LIQUID CONCENTRATE (ACID) FOR BICARBONATE DIALYSIS ... HD-7A LIQUID CONCENTRATE (ACID) FOR BICARBONATE DIALYSIS ... HAEMODIALYSIS CONCENTRATE NKFS-03 (ACID) FOR BICARBONATE DIALYSIS …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … DEXTROSA 5%AD ... DEXTROSA AL 5% ... DEXTROSA AL 10% …
Mupirocin, formerly termed pseudomonic acid A, is a novel antibacterial agent with a unique chemical structure and mode of action apart from other antibiotic agents. Produced by fermentation using the organism Pseudomonas fluorescens, mupirocin is a naturally-occurring antibiotic that displays a broad-specturm activity against many gram-positive bacteria and certain gram-negative...
Approved
Investigational
Vet approved
Matched Synonyms: … Pseudomonic acid ... Pseudomonic acid A ... ,3S)-3- [(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl] oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid
Matched Iupac: … 2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl}oxan-2-yl]-3-methylbut-2-enoyl]oxy}nonanoic acid
Matched Description: … Mupirocin, formerly termed pseudomonic acid A,[A178531] is a novel antibacterial agent with a unique ... and traumatic skin lesions due to secondary skin infections caused by _S. aureus_ and _S. pyogenes_. ... chemical structure and mode of action apart from other antibiotic agents. …
Matched Mixtures name: … Pre and Post Sx Pouch …
Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic...
Approved
Investigational
Matched Synonyms: … 1-(Aminomethyl)cyclohexaneacetic acid
Matched Iupac: … 2-[1-(aminomethyl)cyclohexyl]acetic acid
Matched Description: … Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid ([GABA ... It is structurally and functionally related to another GABA derivative, [pregabalin]. ... other anti-epileptics, such as a relatively benign adverse effect profile, wide therapeutic index, and
Matched Categories: … Gabapentin and Prodrugs ... Amino Acids, Peptides, and Proteins …
A guanido-neuraminic acid that is used to inhibit neuraminidase.
Approved
Investigational
Matched Synonyms: … 4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid ... 5-acetamido-2,6-anhydro-3,4,5-trideoxy-4-guanidino-D-glycero-D-galacto-non-2-enonic acid ... acetylamino)-4-carbamimidamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
Matched Iupac: … diaminomethylidene)amino]-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
Matched Description: … A guanido-neuraminic acid that is used to inhibit neuraminidase. …
Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body. It is on the World Health Organization Model List of Essential Medicines. Edetate calcium disodium was granted FDA approval on 16 July 1953.
Approved
Matched Synonyms: … Edetic acid calcium disodium salt …
Matched Description: … Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores …
Matched Categories: … Diet, Food, and Nutrition …
Technetium Tc-99m oxidronate, also known as 99mTc-methylene diphosphonate, is a radiopharmaceutical agent. A radiopharmaceutical is defined as a medicinal formulation containing radioisotopes that are used in major clinical areas for diagnosis and/or therapy. The radiopharmaceuticals based on technetium-99m are widely used for diagnostic purposes because 99mTc has a versatile chemistry...
Approved
Matched Synonyms: … Oxidronic acid 99mtc-complex …
Matched Iupac: … [hydroxy(phosphono)methyl]phosphonic acid (⁹⁹Tc)technetium …
Matched Description: … [L1140] It was developed by Mallinkrodt nuclear and FDA approved on February 18, 1981. ... medicinal formulation containing radioisotopes that are used in major clinical areas for diagnosis and
Matched Categories: … technetium (99mTc) oxidronic acid
Displaying drugs 76 - 100 of 14929 in total