Displaying drugs 101 - 125 of 5301 in total
Donepezil
In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some...
Approved
Matched Iupac: … 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one …
Matched Mixtures name: … DOMINGO 5/5/80 MG EFERVESAN TABLET, 30 ADET ... DOMINGO 5/5/80 MG EFERVESAN TABLET, 90 ADET ... EBICOMB 5 MG/5 MG EFERVESAN TABLET, 28 ADET …
Matched Products: … Arimac 5 (Donepezil hydrochloride Tablets 5 mg) ... เอไมซ์ 5 ... Donecept-5 (Donepezil Hydrochloride Tablets 5 mg ) …
Matched Mixtures name: … DOMINGO 5/5/80 MG EFERVESAN TABLET, 30 ADET ... DOMINGO 5/5/80 MG EFERVESAN TABLET, 90 ADET ... EBICOMB 5 MG/5 MG EFERVESAN TABLET, 28 ADET …
Matched Products: … Arimac 5 (Donepezil hydrochloride Tablets 5 mg) ... เอไมซ์ 5 ... Donecept-5 (Donepezil Hydrochloride Tablets 5 mg ) …
Carya ovata pollen
Carya ovata pollen is the pollen of the Carya ovata plant. Carya ovata pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Eastern 8 Tree Pollen Mix ... Eastern 8 Tree Pollen Mix ... Eastern 8 Tree Pollen Mix …
Cefaclor
Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.
Approved
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic …
Matched Salts cas: … 70356-03-5 …
Matched Products: … ./5มล.) ... ./5มล.) ... DISTACLOR 125 MG/5 ML …
Matched Salts cas: … 70356-03-5 …
Matched Products: … ./5มล.) ... ./5มล.) ... DISTACLOR 125 MG/5 ML …
Tipiracil
Tipiracil is a thymidine phosphorylase inhibitor. It is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. The main function of Tipiracil in TAS-102 is to increase trifluridine bioavailability by inhibiting its catabolism. TAS-102 is indicated for the treatment of metastatic colorectal cancer which has been...
Approved
Investigational
Matched Synonyms: … 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrimidinedione ... 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1H-pyrimidine-2,4-dione …
Matched Iupac: … 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Iupac: … 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Birch bark extract
Birch bark extract is rich in triterpenoids with beneficial biological and pharmacological activities. Some of the compounds identified in it include betulin, lupeol, betulinic acid, oleanolic acid, and erythrodiol. Birch bark extract is obtained from the white part of the birch tree bark, and the main species of trees used...
Approved
Experimental
Nimesulide
Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. Due to concerns about the risk of hepatotoxicity, nimesulide has...
Approved
Investigational
Withdrawn
Matched Mixtures name: … ETNA COMBO 100 MG/8 MG TABLET, 14 ADET ... NİMES COMBO 100 MG / 8 MG TABLET , 14 ADET ... EMULİD PLUS % 1 + % 5 JEL …
Etodolac
Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Approved
Investigational
Vet approved
Matched Mixtures name: … ETOTIO 400 MG/8 MG FILM TABLET, 20 ADET ... ETOLAX 500 MG/8 MG FİLM KAPLI TABLET, 14 ADET …
Conivaptan
Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). It was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH). Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2).
Approved
Investigational
Matched Synonyms: … 4'-((4,5-dihydro-2-methylimidazo(4,5-d)(1)benzazepin-6(1H)-yl)carbonyl)-2-biphenylcarboxanilide …
Matched Iupac: … N-(4-{4-methyl-3,5,9-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14),2(6),3,10,12-pentaene-9-carbonyl}phenyl …
Matched Salts cas: … 168626-94-6 …
Matched Iupac: … N-(4-{4-methyl-3,5,9-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14),2(6),3,10,12-pentaene-9-carbonyl}phenyl …
Matched Salts cas: … 168626-94-6 …
Enzalutamide
Enzalutamide is an androgen receptor (AR) inhibitor for the treatment of castration-resistant prostate cancer (CRPC), both metastatic and non-metastatic. It is a second-generation antiandrogen agent that the FDA approved on August 31, 2012.[L40639, A252667] Although androgen deprivation therapy (ADT) is the first-line treatment of prostate cancer and remission can be...
Approved
Cyclothiazide
As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter....
Approved
Matched Synonyms: … 6-chloro-3-(2-norbornen-5-yl)-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ... 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide ... 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide …
Matched Iupac: … 3-{bicyclo[2.2.1]hept-5-en-2-yl}-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Iupac: … 3-{bicyclo[2.2.1]hept-5-en-2-yl}-6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Quetiapine
Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high...
Approved
Matched Categories: … Serotonin 5-HT1 Receptor Antagonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT1A Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists …
Nizatidine
A histamine H2 receptor antagonist with low toxicity that inhibits gastric acid secretion. The drug is used for the treatment of duodenal ulcers.
Approved
Matched Synonyms: … N-(4-(6-Methylamino-7-nitro-2-thia-5-aza-6-hepten-1-yl)-2-thiazolylmethyl)-N,N-dimethylamine …
Matched Products: … AMPUL, 5 ADET …
Matched Products: … AMPUL, 5 ADET …
Tedizolid phosphate
Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Matched Synonyms: … [(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl …
Matched Iupac: … {[(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin- ... 5-yl]methoxy}phosphonic acid …
Matched Products: … SİVEXTRO 200 MG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ, 6 ADET …
Matched Iupac: … {[(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin- ... 5-yl]methoxy}phosphonic acid …
Matched Products: … SİVEXTRO 200 MG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ, 6 ADET …
Adenosine
The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Synonyms: … (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol ... 9-β-D-ribofuranosyl-9H-purin-6-amine ... 6-Amino-9-beta-D-ribofuranosyl-9H-purine …
Matched Iupac: … (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Products: … ADENOSIN-L.M. 5 MG/ML ENJ/INF. ICIN COZ. ICEREN 2 ML 10 FLAKON ... ADENOSIN-L.M. 5 MG/ML ENJ/INF. ICIN COZ. ICEREN 10 ML 10 FLAKON ... ADENOSIN-L.M. 5 MG/ML ENJ/INF. ICIN COZ. ICEREN 50 ML 10 FLAKON …
Matched Iupac: … (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Products: … ADENOSIN-L.M. 5 MG/ML ENJ/INF. ICIN COZ. ICEREN 2 ML 10 FLAKON ... ADENOSIN-L.M. 5 MG/ML ENJ/INF. ICIN COZ. ICEREN 10 ML 10 FLAKON ... ADENOSIN-L.M. 5 MG/ML ENJ/INF. ICIN COZ. ICEREN 50 ML 10 FLAKON …
Dantron
Withdrawn from the Canadian, US, and UK markets in 1998 due to genotoxicity.
Approved
Investigational
Withdrawn
Betula nigra pollen
Betula nigra pollen is the pollen of the Betula nigra plant. Betula nigra pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Eastern 8 Tree Pollen Mix ... Eastern 8 Tree Pollen Mix ... Eastern 8 Tree Pollen Mix …
Naxitamab
Naxitamab (humanized 3F8, hu3F8) is an IgG1 monoclonal antibody directed against the oncofetal differentiation antigen GD2 disialoganglioside.[L24454,A224604] Normally expressed during fetal development and in mature neurons, pain fibers, and skin cells, GD2 constitutes a highly efficient target in the treatment of neuroblastoma - it is widely expressed across and within...
Approved
Pancrelipase amylase
Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. The amylases are enzymes that help in the chemical process of digestion by hydrolizing starch into more available saccharide forms. The pancrelipase amylase is a...
Approved
Matched Mixtures name: … Creon 5 Minimicrospheres ... Creon Minimicrospheres 6 ... Creon 8 Cap …
Pancrelipase protease
Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. The pancrelipase protease is a mix of enzymes, formed by trypsin and chymotrypsin, that proteolytically cleave peptide bonds and are involved in food digestion.[A32742, L2543]...
Approved
Matched Mixtures name: … Creon 5 Minimicrospheres ... Creon Minimicrospheres 6 ... Creon 8 Cap …
Pancrelipase lipase
Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. The pancrelipase lipase is an enzyme secreted by the pancreas that is responsible for the hydrolysis of dietary fat molecules in the human digestive system....
Approved
Matched Mixtures name: … Creon 5 Minimicrospheres ... Creon Minimicrospheres 6 ... Creon 8 Cap …
Mezlocillin
Semisynthetic ampicillin-derived acylureido penicillin. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections.
Approved
Investigational
Matched Synonyms: … (2S,5R,6R)-3,3-dimethyl-6-{[(2R)-2-({[3-(methylsulfonyl)-2-oxoimidazolidin-1-yl]carbonyl}amino)-2-phenylacetyl …
Matched Iupac: … (2S,5R,6R)-6-[(2R)-2-[(3-methanesulfonyl-2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetamido]-3,3- …
Matched Iupac: … (2S,5R,6R)-6-[(2R)-2-[(3-methanesulfonyl-2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetamido]-3,3- …
Bithionol
Bithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the NDA's for bithionol drug products were withdrawn on October 24, 1967 (see the Federal Register of October 31, 1967 (32...
Approved
Withdrawn
Matched Iupac: … 2,4-dichloro-6-[(3,5-dichloro-2-hydroxyphenyl)sulfanyl]phenol …
Matched Salts cas: … 6385-58-6 …
Matched Salts cas: … 6385-58-6 …
Linzagolix
Linzagolix is a non-peptide, selective antagonist of the gonadotropin-releasing hormone (GnRH) receptor. It has been studied for the treatment of estrogen-dependent conditions such as uterine fibroids and endometriosis.[A253642,A253647] It is similar to other GnRH receptor antagonists like cetrorelix, relugolix, and elagolix.
Uterine fibroids occur in >70% of women of reproductive...
Approved
Matched Synonyms: … Thieno(3,4-d)pyrimidine-5-carboxylic acid, 3-(5-((2,3-difluoro-6-methoxyphenyl)methoxy)-2-fluoro-4-methoxyphenyl ... 3-(5-((2,3-difluoro-6-methoxyphenyl)methoxy)-2-fluoro-4-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno ... (3,4-d)pyrimidine-5-carboxylic acid …
Matched Iupac: … 3-{5-[(2,3-difluoro-6-methoxyphenyl)methoxy]-2-fluoro-4-methoxyphenyl}-2,4-dioxo-1H,2H,3H,4H-thieno[3,4 ... -d]pyrimidine-5-carboxylic acid …
Matched Iupac: … 3-{5-[(2,3-difluoro-6-methoxyphenyl)methoxy]-2-fluoro-4-methoxyphenyl}-2,4-dioxo-1H,2H,3H,4H-thieno[3,4 ... -d]pyrimidine-5-carboxylic acid …
Cobicistat
Cobicistat, marketed under the name Tybost (formerly GS-9350), indicated for treating infection with human immunodeficiency virus (HIV). Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered agents that are metabolized...
Approved
Matched Synonyms: … 1,3-thiazol-5-ylmethyl [(2R,5R)-5-{[(2S)-2-({[(2-isopropyl-1,3-thiazol-4-yl)methyl](methyl)carbamoyl} …
Matched Iupac: … (1,3-thiazol-5-yl)methyl N-[(2R,5R)-5-[(2S)-2-{[methyl({[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl})carbamoyl …
Matched Iupac: … (1,3-thiazol-5-yl)methyl N-[(2R,5R)-5-[(2S)-2-{[methyl({[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl})carbamoyl …
Enasidenib
Enasidenib is an orally available treatment for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) with specific mutations in the isocitrate dehydrogenase 2 (IDH2) gene, which is a recurrent mutation detected in 12-20% of adult patients with AML [A20344, A20345]. Patients eligible for this treatment...
Approved
Investigational
Matched Synonyms: … 2-Methyl-1-(4-(6-(trifluoromethyl)pyridin-2-yl)-6-(2-(trifluoromethyl)pyridin-4-ylamino)-1,3,5-triazin …
Matched Iupac: … 2-methyl-1-({4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin …
Matched Salts cas: … 1650550-25-6 …
Matched Iupac: … 2-methyl-1-({4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin …
Matched Salts cas: … 1650550-25-6 …
Displaying drugs 101 - 125 of 5301 in total