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Displaying drugs 176 - 200 of 14501 in total
Dimercaprol is a traditional chelating agent developed by British biochemists at Oxford University during World War II. It was developed as an experimental antidote against the arsenic-based poison gas Lewisite. It has been used clinically since 1949 in arsenic, cadmium and mercury poisoning. In addition, it has in the past...
Approved
Matched Description: … It has been used clinically since 1949 in arsenic, cadmium and mercury poisoning. ... Dimercaprol has toxic potential, and its use may be followed by a variety of adverse effects. …
Platango seeds refer to the seeds collected from various species of plantago trees. It is found in some laxatives for treating occasional constipation and restoring regularity in bowel movements. Its potential benefit in maintaining remission in ulcerative colitis has been studied . Regardless, this agent is most predominantly used as...
Approved
Investigational
Matched Description: … It is found in some laxatives for treating occasional constipation and restoring regularity in bowel …
Matched Categories: … Herbs and Natural Products …
Matched Products: … Up and Up Fiber Therapy ... up and up fiber therapy Natural Fiber ... Lidl Orange Smooth Fiber Powder Naturally and Artificially Flavored …
Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Description: … Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. ... [A251395] Teriparatide is used in the treatment of osteoporosis in men and women.[L42590, L42595] ... [A251395] First approved in the United States in November 2002 and in Europe in April 2003,[A251400] …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Calcium Homeostasis ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Parathyroid Hormones and Analogues …
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Description: … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... [L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence ... used to manage severe muscle spasms of cerebral or spinal cord origins, including multiple sclerosis and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Iron deficiency anemia is a large public health concern worldwide, especially in young children, infants, and women of childbearing age. This type of anemia occurs when iron intake, iron stores, and iron loss do not adequately support the formation of erythrocytes, also known as red blood cells. Ferrous sulfate is...
Approved
Matched Description: … deficiency anemia is a large public health concern worldwide, especially in young children, infants, and ... It is the gold standard of oral iron therapy in the UK and many other countries.[L2234,L2246] ... [A190804] This type of anemia occurs when iron intake, iron stores, and iron loss do not adequately support …
Matched Mixtures name: … Phytofortis + Calcium A-D ... Tri-Vitamin with iron and fluoride ... Multi-Vit with Fluoride and Iron …
Approved
Vet approved
Matched Categories: … Hydrocortisone and derivatives ... hydrocortisone butyrate and antiseptics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Approved
Investigational
Vet approved
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Approved
Vet approved
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Approved
Vet approved
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Approved
Vet approved
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Description: … [A178192] It promotes sodium and water excretion and potassium retention. ... Spironolactone is a potassium-sparing diuretic. ... It binds to mineralocorticoid receptors and functions as aldosterone antagonists. …
Matched Mixtures name: … Spironolactone and Hydrochlorothiazide ... Spironolactone and Hydrochlorothiazide ... Spironolactone and Hydrochlorothiazide …
Matched Categories: … Potassium-Sparing Diuretics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Mineral oil, or paraffin oil, is a mixture of higher alkanes from a mineral source, such as petroleum. Petroleum mineral oil is manufactured from crude oils by vacuum distillation to produce several distillates and a residual oil that are then further refined. During the modern refining process, aromatics are reduced...
Approved
Vet approved
Matched Description: … Mineral oil is a common ingredient in baby lotions, cold creams, ointments and cosmetics to treat and ... prevent dry, rough, scaly, itchy skin and minor skin irritations. ... Petroleum mineral oil is manufactured from crude oils by vacuum distillation to produce several distillates and
Matched Mixtures name: … Hand and Skin Shield ... Nature and Health Beauty (Moisturizing Cream, Whitening Cream) (Mineral Oil and Glycerin) ... Nature and Health Beauty (Moisturizing Cream, Whitening Cream) (Mineral Oil and Glycerin) …
Matched Categories: … Alimentary Tract and Metabolism ... Basic Ointments and Protectants ... Softener and Emollient Laxatives …
Matched Products: … Pure and Gentle ... Butler Hemorrhoid and Perineal …
Approved
Nutraceutical
Matched Mixtures name: … C-1000 Plus Zinc & Potassium
Matched Categories: … Vitamin C and analogues ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Approved
Illicit
Matched Description: … A short-acting opioid anesthetic and analgesic derivative of fentanyl. ... It produces an early peak analgesic effect and fast recovery of consciousness. ... effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and
Matched Categories: … Fentanyl and fentanyl analogues …
Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic...
Approved
Investigational
Matched Description: … It is structurally and functionally related to another GABA derivative, [pregabalin]. ... other anti-epileptics, such as a relatively benign adverse effect profile, wide therapeutic index, and
Matched Categories: … Gabapentin and Prodrugs ... Amino Acids, Peptides, and Proteins …
Lercanidipine is a calcium channel blocker of the dihydropyridine class. It is sold under various commercial names including Zanidip.
Approved
Investigational
Matched Description: … Lercanidipine is a calcium channel blocker of the dihydropyridine class. …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... Calcium Channel Blockers ... valsartan and lercanidipine …
Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid that is structurally similar to opiate receptor agonists such as diphenoxylate and haloperidol. Due to...
Approved
Matched Description: … withdrawal symptoms and to induce euphoria. ... [L42785] The drug was first synthesized in 1969 and used medically in 1976. ... [A6249] Due to pharmacological properties, loperamide has been misused and abused to self-manage opioid …
Matched Mixtures name: … Anti Diarrheal and Anti Gas ... Anti Diarrheal and Anti Gas ... Up and Up Anti Diarrheal Anti Gas …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up anti diarrheal ... Berkley and Jensen Anti Diarrheal ... Foster and Thrive Anti-diarrheal …
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Approved
Investigational
Matched Description: … It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents …
Matched Mixtures name: … Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Categories: … Medications that reduce magnesium levels ... Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars ... Metabolic Side Effects of Drugs and Substances …
Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by...
Approved
Illicit
Matched Description: … and endoscopic procedures as pre-anesthetic medication, and as an adjunct to local anesthesia. ... This drug is unique from others in this class due to its rapid onset of effects and short duration of ... short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Products: … Midazolam in Sodium Chloride
Tranexamic acid is a synthetic derivative of lysine used as an antifibrinolytic in the treatment and prevention of major bleeding. It possesses a similar mechanism of action to aminocaproic acid but is approximately 10-fold more potent. It was first patented in 1957 and received its initial US approval in 1986.
Approved
Matched Description: … Tranexamic acid is a synthetic derivative of [lysine] used as an antifibrinolytic in the treatment and ... [L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986. …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Matched Products: … Tranexamic Acid In Sodium Chloride
Formestane was the first selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. Formestane suppresses estrogen production from anabolic steroids or prohormones. Formestane is also a prohormone of 4-hydroxytestosterone, an active steroid with weak androgenic activity and mild aromatase inhibitor activity....
Approved
Investigational
Withdrawn
Matched Description: … and less expensive than formestane, formestane lost popularity. ... With the discovery of newer, non-steroidal and steroidal, aromatase inhibitors which were orally active ... Formestane is also a prohormone of 4-hydroxytestosterone, an active steroid with weak androgenic activity and
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Glipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus. It was first introduced in 1984 and is available in various countries including Canada and the U.S. According to the 2018 Clinical Practice...
Approved
Investigational
Matched Description: … It was first introduced in 1984 [A179491] and is available in various countries including Canada and ... [A179485] Glipizide was first approved by the FDA in 1994 and is available in extended-release tablets ... onset of action with the shortest half-life and duration of action, reducing the risk for long-lasting …
Matched Mixtures name: … Glipizide and Metformin HCl ... Glipizide and Metformin HCl ... Glipizide and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism …
Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood pressure. This drug has been discontinued by the FDA.
Approved
Matched Description: … peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. ... Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to …
Matched Categories: … pinacidil and diuretics ... Potassium Channel Opener …
Benzoin is a white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide, and is used in organic syntheses. This should not be confused with benzoin gum from STYRAX (see DB11222). Benzoin is an FDA-approved colour additive used for marking fruits and vegetables.
Approved
Experimental
Matched Description: … , and is used in organic syntheses. ... Benzoin is a white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide ... Benzoin is an FDA-approved colour additive used for marking fruits and vegetables. …
A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
Approved
Investigational
Matched Description: … It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. ... of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Displaying drugs 176 - 200 of 14501 in total