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Displaying drugs 1 - 25 of 13309 in total
Omega-3-acid ethyl esters
Omega-3-acid ethyl esters are prescription drugs that contain eicosapentaenoic acid-ethyl ester (EPA) and docosahexaenoic acid-ethyl ester (DHA) that are used in combination with changes in diet to lower triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia[FDA Label] . Omega-3-acid ethyl esters are currently marketed in the US, EU,...
Approved
Investigational
Matched Synonyms: … Omega-3-acid ethyl esters ... Omega-3 fatty acid ethyl esters …
Matched Name: … Omega-3-acid ethyl esters …
Matched Description: … Omega-3-acid ethyl esters are prescription drugs that contain eicosapentaenoic acid-ethyl ester (EPA) ... Omega-3-acid ethyl esters are currently marketed in the US, EU, and many other regions under the brand …
Matched Mixtures name: … Omega-3 Well Pack ... Omega-3 Well Pack ... Omega-3 Rx Complete …
Matched Categories: … Fatty Acids, Omega-3 …
Matched Products: … OMEGA 3 DOC ... OMEGA 3 TEVA ... OMEGA 3 MYLAN …
Matched Name: … Omega-3-acid ethyl esters …
Matched Description: … Omega-3-acid ethyl esters are prescription drugs that contain eicosapentaenoic acid-ethyl ester (EPA) ... Omega-3-acid ethyl esters are currently marketed in the US, EU, and many other regions under the brand …
Matched Mixtures name: … Omega-3 Well Pack ... Omega-3 Well Pack ... Omega-3 Rx Complete …
Matched Categories: … Fatty Acids, Omega-3 …
Matched Products: … OMEGA 3 DOC ... OMEGA 3 TEVA ... OMEGA 3 MYLAN …
Bordetella pertussis fimbriae 2/3 antigen
Bordetella pertussis fimbriae 2/3 antigen is a vaccine for the prophylaxis of the disease caused by Bordetella pertussis which is a a Gram-negative coccobacillus that expresses two serologically distinct fimbriae (Fim2 and Fim3).
Approved
Investigational
Matched Synonyms: … Bordetella pertussis fimbriae 2/3 vaccine, inactivated …
Matched Name: … Bordetella pertussis fimbriae 2/3 antigen …
Matched Description: … Bordetella pertussis fimbriae 2/3 antigen is a vaccine for the prophylaxis of the disease caused by Bordetella ... pertussis which is a a Gram-negative coccobacillus that expresses two serologically distinct fimbriae …
Matched Mixtures name: … FORMALDEHYDE INACTIVATED), BORDETELLA PERTUSSIS PERTACTIN ANTIGEN, and BORDETELLA PERTUSSIS FIMBRIAE 2/3 …
Matched Name: … Bordetella pertussis fimbriae 2/3 antigen …
Matched Description: … Bordetella pertussis fimbriae 2/3 antigen is a vaccine for the prophylaxis of the disease caused by Bordetella ... pertussis which is a a Gram-negative coccobacillus that expresses two serologically distinct fimbriae …
Matched Mixtures name: … FORMALDEHYDE INACTIVATED), BORDETELLA PERTUSSIS PERTACTIN ANTIGEN, and BORDETELLA PERTUSSIS FIMBRIAE 2/3 …
1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol))
Palmitoyloleoyl-phosphatidylglycerol was a component of Surfaxin, discontinued in 2017, which acted as a surfactant [FDA Label]. The product was meant to compensate for alveolar surfactant deficiency and reduce to likelihood of alveolar collapse leading to acute respiratory collapse.
Approved
Experimental
Matched Synonyms: … 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol ... 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol ... 1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)) …
Matched Name: … 1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)) …
Matched Iupac: … (2,3-dihydroxypropoxy)[(2R)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propoxy]phosphinic acid …
Matched Description: … a surfactant [FDA Label]. ... Palmitoyloleoyl-phosphatidylglycerol was a component of Surfaxin, discontinued in 2017, which acted as …
Matched Salts cas: … 268550-95-4 …
Matched Salts name: … 1-palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt …
Matched Name: … 1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)) …
Matched Iupac: … (2,3-dihydroxypropoxy)[(2R)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propoxy]phosphinic acid …
Matched Description: … a surfactant [FDA Label]. ... Palmitoyloleoyl-phosphatidylglycerol was a component of Surfaxin, discontinued in 2017, which acted as …
Matched Salts cas: … 268550-95-4 …
Matched Salts name: … 1-palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt …
1,2-icosapentoyl-sn-glycero-3-phosphoserine
Approved
Experimental
Matched Name: … 1,2-icosapentoyl-sn-glycero-3-phosphoserine …
Matched Iupac: … 2-amino-3-[({2-[(6Z,9Z,12Z,15Z,18Z)-henicosa-6,9,12,15,18-pentaenoyloxy]-3-[(5Z,8Z,11Z,14Z,17Z)-icosa …
Matched Salts name: … 1,2-icosapentoyl-sn-glycero-3-phosphoserine calcium …
Matched Iupac: … 2-amino-3-[({2-[(6Z,9Z,12Z,15Z,18Z)-henicosa-6,9,12,15,18-pentaenoyloxy]-3-[(5Z,8Z,11Z,14Z,17Z)-icosa …
Matched Salts name: … 1,2-icosapentoyl-sn-glycero-3-phosphoserine calcium …
Sertraline
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects.
Several weeks of therapy with sertraline may be required before...
Approved
Matched Synonyms: … (1S,4S)-sertraline ... (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine …
Matched Iupac: … (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine …
Matched Description: … Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor …
Matched Categories: … Monoamine Oxidase A Substrates …
Matched Iupac: … (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine …
Matched Description: … Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor …
Matched Categories: … Monoamine Oxidase A Substrates …
Artemether
Artemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and may be used to treat infections caused by P. falciparum and unidentified Plasmodium species, including...
Approved
Matched Synonyms: … (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13 ... 10-methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13 …
Matched Iupac: … (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13 …
Matched Iupac: … (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13 …
Vorapaxar
Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or with peripheral arterial disease (PAD). By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related platelet aggregation.
Approved
Matched Synonyms: … Ethyl N-[(3R,3aS,4S,4aR,7R,8aR,9aR)-4-[(E)-2-[5-(3-fluorophenyl)-2-pyridyl]vinyl]-3-methyl-1-oxo-3a,4,4a ... [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-Fluorophényl)-2-pyridinyl]vinyl}-1-méthyl-3-oxododécahydronaphto ... -1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester …
Matched Iupac: … ethyl N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1-methyl-3-oxo-dodecahydronaphtho …
Matched Description: … Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) ... indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history ... By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related …
Matched Iupac: … ethyl N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1-methyl-3-oxo-dodecahydronaphtho …
Matched Description: … Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) ... indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history ... By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related …
Phenprocoumon
Coumarin derivative that acts as a long-acting oral anticoagulant.
Approved
Investigational
Matched Synonyms: … 3-(1-Phenylpropyl)-4-hydroxycoumarin ... 3-(1'-Phenyl-propyl)-4-oxycoumarin ... 3-(alpha-Ethylbenzyl)-4-hydroxycoumarin …
Matched Iupac: … 4-hydroxy-3-(1-phenylpropyl)-2H-chromen-2-one …
Matched Description: … Coumarin derivative that acts as a long-acting oral anticoagulant. …
Matched Categories: … 4-Hydroxycoumarins ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … PHENPROGAMMA 3 ... MARCUPHEN ABZ 3 MG TAB ... PHENPRO RATIOPHARM 3 MG …
Matched Iupac: … 4-hydroxy-3-(1-phenylpropyl)-2H-chromen-2-one …
Matched Description: … Coumarin derivative that acts as a long-acting oral anticoagulant. …
Matched Categories: … 4-Hydroxycoumarins ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … PHENPROGAMMA 3 ... MARCUPHEN ABZ 3 MG TAB ... PHENPRO RATIOPHARM 3 MG …
Zanamivir
A guanido-neuraminic acid that is used to inhibit neuraminidase.
Approved
Investigational
Matched Synonyms: … (2R,3R,4S)-3-(acetylamino)-4-carbamimidamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran- ... 4-guanidino-Neu5Ac2en ... 4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid …
Matched Iupac: … (2R,3R,4S)-4-[(diaminomethylidene)amino]-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran …
Matched Description: … A guanido-neuraminic acid that is used to inhibit neuraminidase. …
Matched Iupac: … (2R,3R,4S)-4-[(diaminomethylidene)amino]-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran …
Matched Description: … A guanido-neuraminic acid that is used to inhibit neuraminidase. …
Bumetanide
Bumetanide is a sulfamyl diuretic.
Approved
Matched Synonyms: … 3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Iupac: … 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Description: … Bumetanide is a sulfamyl diuretic. …
Matched Iupac: … 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Description: … Bumetanide is a sulfamyl diuretic. …
Tobramycin
Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Synonyms: … O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl ... -(1-4))-2-deoxy-D-streptamine ... 3'-Deoxykanamycin B …
Matched Iupac: … (2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5 …
Matched Description: … A232299, L32739] However, tobramycin can also be administered intravenously and topically to treat a ... ., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive ... A232349, L32739, L32749] Tobramycin was approved by the FDA in 1975 and is currently available in a …
Matched Mixtures name: … DEXAVITAL TOBRAMICIDADEXAMETASONA(3 MG+1MG)/ML ... TOBRALOT 5 MG+3 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Products: … Bramitob 300 mg/4 ml Lösung für einen Vernebler ... Braun 3 mg/ml Infusionslösung ... TOBEL 20 MG/2 ML AMPUL, 3 ADET …
Matched Iupac: … (2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5 …
Matched Description: … A232299, L32739] However, tobramycin can also be administered intravenously and topically to treat a ... ., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive ... A232349, L32739, L32749] Tobramycin was approved by the FDA in 1975 and is currently available in a …
Matched Mixtures name: … DEXAVITAL TOBRAMICIDADEXAMETASONA(3 MG+1MG)/ML ... TOBRALOT 5 MG+3 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Products: … Bramitob 300 mg/4 ml Lösung für einen Vernebler ... Braun 3 mg/ml Infusionslösung ... TOBEL 20 MG/2 ML AMPUL, 3 ADET …
Sulfamethoxazole
Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. It is generally given in combination with trimethoprim, which inhibits a sequential step in bacterial folic acid synthesis - these agents work synergistically to block two consecutive steps in the biosynthesis of nucleic acids and...
Approved
Matched Synonyms: … 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide ... 3-Sulfanilamido-5-methylisoxazole ... 3-(p-Aminophenylsulfonamido)-5-methylisoxazole …
Matched Iupac: … 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzene-1-sulfonamide …
Matched Description: … Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis ... [L11830] It is generally given in combination with [trimethoprim], which inhibits a sequential step in ... [L11830] In this combination, sulfamethoxazole is useful for the treatment of a variety of bacterial …
Matched Mixtures name: … SULFAWAL - S ... CO - STAR D/S ... COMOXOLE D/S TABLETS …
Matched Iupac: … 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzene-1-sulfonamide …
Matched Description: … Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis ... [L11830] It is generally given in combination with [trimethoprim], which inhibits a sequential step in ... [L11830] In this combination, sulfamethoxazole is useful for the treatment of a variety of bacterial …
Matched Mixtures name: … SULFAWAL - S ... CO - STAR D/S ... COMOXOLE D/S TABLETS …
Brompheniramine
Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Approved
Matched Synonyms: … [3-(4-Bromo-phenyl)-3-pyridin-2-yl-propyl]-dimethyl-amine ... 3-(4-bromophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine ... 3-(p-bromophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine …
Matched Iupac: … [3-(4-bromophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Mixtures name: … Altidec A …
Matched Products: … ฟรอสซี่ พิงค์ 4 ... BOMEX TABLET 4 mg …
Matched Iupac: … [3-(4-bromophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Mixtures name: … Altidec A …
Matched Products: … ฟรอสซี่ พิงค์ 4 ... BOMEX TABLET 4 mg …
Selpercatinib
Selpercatinib is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes.[A202055, A202052, L13604] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark of many cancers. Although multikinase inhibitors, including cabozantinib, ponatinib, sorafenib, sunitinib, and vandetanib, have shown efficacy in RET-driven cancers, their...
Approved
Investigational
Matched Synonyms: … -yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile ... 6-(2-hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3 …
Matched Iupac: … -yl}pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile ... 6-(2-hydroxy-2-methylpropoxy)-4-(6-{6-[(6-methoxypyridin-3-yl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3 …
Matched Description: … Selpercatinib is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs ... [A202055, A202052, L13604] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark …
Matched Iupac: … -yl}pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile ... 6-(2-hydroxy-2-methylpropoxy)-4-(6-{6-[(6-methoxypyridin-3-yl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3 …
Matched Description: … Selpercatinib is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs ... [A202055, A202052, L13604] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark …
Gefitinib
Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.
Approved
Investigational
Matched Synonyms: … N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine ... 4-(3'-chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline …
Matched Iupac: … N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine …
Matched Description: … Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. ... Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant …
Matched Iupac: … N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine …
Matched Description: … Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. ... Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant …
Acenocoumarol
Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation. Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. Patients...
Approved
Investigational
Matched Synonyms: … 4-Hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one ... 4-Hydroxy-3-(1-(4-nitrophenyl)-3-oxobutyl)-2H-1-benzopyran-2-one ... 3-(alpha-Acetonyl-4-nitrobenzyl)-4-hydroxycoumarin …
Matched Iupac: … 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Description: … Acenocoumarol is a coumarin derivative used as an anticoagulant. …
Matched Categories: … 4-Hydroxycoumarins ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index …
Matched Products: … Sintrom 4 mg Tabletten …
Matched Iupac: … 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Description: … Acenocoumarol is a coumarin derivative used as an anticoagulant. …
Matched Categories: … 4-Hydroxycoumarins ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index …
Matched Products: … Sintrom 4 mg Tabletten …
Rutin
A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.
Approved
Experimental
Investigational
Matched Synonyms: … -4H-1-benzopyran-4-one ... 3-Rutinosyl quercetin ... Quercetin 3-rutinoside …
Matched Iupac: … 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5 ... -trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one …
Matched Description: … A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, …
Matched Salts cas: … 250249-75-3 …
Matched Mixtures name: … KORDEL`S NUTRITIME TABLET ... KORDEL`S C TIME ACID FREE C 1000MG TABLET …
Matched Iupac: … 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5 ... -trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-4H-chromen-4-one …
Matched Description: … A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, …
Matched Salts cas: … 250249-75-3 …
Matched Mixtures name: … KORDEL`S NUTRITIME TABLET ... KORDEL`S C TIME ACID FREE C 1000MG TABLET …
Vadadustat
One of the most common symptoms of advanced renal disease is anemia, caused primarily by the inability of the kidney to respond to anemic conditions with a corresponding increase in erythropoietin (EPO) production. The treatment of anemia associated with chronic kidney disease (CKD) has traditionally involved the administration of exogenous...
Approved
Investigational
Matched Synonyms: … N-(5-(3-Chlorophenyl)-3-hydroxypyridine-2-carbonyl)glycine ... Glycine, N-((5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl)carbonyl)- …
Matched Iupac: … 2-{[5-(3-chlorophenyl)-3-hydroxypyridin-2-yl]formamido}acetic acid …
Matched Description: … disease is anemia, caused primarily by the inability of the kidney to respond to anemic conditions with a ... These transcription factors serve a multitude of roles, including the stimulation of erythropoiesis. ... [A244165] A relatively new and alternative treatment option for patients with anemia associated with …
Matched Iupac: … 2-{[5-(3-chlorophenyl)-3-hydroxypyridin-2-yl]formamido}acetic acid …
Matched Description: … disease is anemia, caused primarily by the inability of the kidney to respond to anemic conditions with a ... These transcription factors serve a multitude of roles, including the stimulation of erythropoiesis. ... [A244165] A relatively new and alternative treatment option for patients with anemia associated with …
Fluphenazine
A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Approved
Matched Synonyms: … 10-(3'-(4''-(β-hydroxyethyl)-1''-piperazinyl)-propyl)-3-trifluoromethylphenothiazine ... 1-(2-hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine ... 4-(3-(-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol …
Matched Iupac: … 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol …
Matched Description: … A phenothiazine used in the treatment of psychoses. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … PROLİXİN DECANOATE 25 MG/ML I.M UZATILMIŞ SALIMLI ENJEKSİYONLUK ÇÖZELTİ, 3 ADET …
Matched Iupac: … 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol …
Matched Description: … A phenothiazine used in the treatment of psychoses. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Products: … PROLİXİN DECANOATE 25 MG/ML I.M UZATILMIŞ SALIMLI ENJEKSİYONLUK ÇÖZELTİ, 3 ADET …
Omacetaxine mepesuccinate
Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies. Omacetaxine mepesuccinate is synthesized from cephalotaxine, which is an extract from the leaves of the plant, Cephalotaxus species. In October 2005, omacetaxine mepesuccinate...
Approved
Investigational
Matched Synonyms: … 3]benzazepin-1-yl] 4-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate ... (2'R,3S,4S,5R)-(−)-homoharringtonine ... 1-[(1S,3aR,14bS)-2-Methoxy-1,5,6,8,9,14b-hexahydro-4H-cyclopenta[a][1,3]dioxolo[4,5-H]pyrrolo[2,1-b][ …
Matched Iupac: … (19)-tetraen-3-yl 1-methyl (3R)-3-hydroxy-3-(4-hydroxy-4-methylpentyl)butanedioate ... (2S,3S,6R)-4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.0^{2,6}.0^{6,10}.0^{15,19}]icosa-1(20),4,13,15 …
Matched Description: … Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and ... protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies …
Matched Salts cas: … 457895-79-3 …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Iupac: … (19)-tetraen-3-yl 1-methyl (3R)-3-hydroxy-3-(4-hydroxy-4-methylpentyl)butanedioate ... (2S,3S,6R)-4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.0^{2,6}.0^{6,10}.0^{15,19}]icosa-1(20),4,13,15 …
Matched Description: … Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and ... protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies …
Matched Salts cas: … 457895-79-3 …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Itraconazole
First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used to treat a variety of infections. It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each possessing three chiral centers. Itraconazole was first approved in the US in 1992 and...
Approved
Investigational
Matched Synonyms: … 3H-1,2,4-TRIAZOL-3-ONE, 4-(4-(4-(4-((2-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1,3-DIOXOLAN ... (±)-1-SEC-BUTYL-4-(P-(4-(P-(((2R*,4S*)-2-(2,4-DICHLOROPHENYL)-2-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1,3-DIOXOLAN ... -4-YL)METHOXY)PHENYL)-1-PIPERAZINYL)PHENYL)-.DELTA. …
Matched Iupac: … 1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan ... -4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one …
Matched Description: … to treat a variety of infections. ... First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used ... [A34257] It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each …
Matched Mixtures name: … Ciclopirox 3% / Itraconazole 5% / Urea 20% ... Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Products: … FUNİT 100 MG KAPSÜL, 4 ADET ... CANDİSTAT 100 MG SERT KAPSÜL, 4 ADET ... ITRAXYL 100 MG MIKROPELLET KAPSUL, 4 ADET …
Matched Iupac: … 1-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan ... -4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one …
Matched Description: … to treat a variety of infections. ... First synthesized in the early 1980s, itraconazole is a broad-spectrum triazole antifungal agent used ... [A34257] It is a 1:1:1:1 racemic mixture of four diastereomers, made up of two enantiomeric pairs, each …
Matched Mixtures name: … Ciclopirox 3% / Itraconazole 5% / Urea 20% ... Fluconazole 4% / Ibuprofen 2% / Itraconazole 1% / Terbinafine HCl 4% …
Matched Products: … FUNİT 100 MG KAPSÜL, 4 ADET ... CANDİSTAT 100 MG SERT KAPSÜL, 4 ADET ... ITRAXYL 100 MG MIKROPELLET KAPSUL, 4 ADET …
Ethosuximide
An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
Approved
Matched Synonyms: … 3-ethyl-3-methylsuccinimide ... 3-methyl-3-ethylsuccinimide ... 3-ethyl-3-methyl-2,5-pyrrolidinedione …
Matched Iupac: … 3-ethyl-3-methylpyrrolidine-2,5-dione …
Matched Iupac: … 3-ethyl-3-methylpyrrolidine-2,5-dione …
Ivabradine
Ivabradine is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and symptomatic chronic heart failure. Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart failure in patients with an ejection fraction of ≤35%, in sinus...
Approved
Matched Synonyms: … 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy ... -2,3,4,5-tetrahydro-1H-3-benzazepin-2-one …
Matched Iupac: … 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy ... -2,3,4,5-tetrahydro-1H-3-benzazepin-2-one …
Matched Description: … Ivabradine is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis ... Recently a new indication was added to treat symptomatic heart failure from dilated cardiomyopathy for ... dose-dependent fashion, resulting in a lower heart rate and thus more blood to flow to the myocardium …
Matched Iupac: … 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy ... -2,3,4,5-tetrahydro-1H-3-benzazepin-2-one …
Matched Description: … Ivabradine is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis ... Recently a new indication was added to treat symptomatic heart failure from dilated cardiomyopathy for ... dose-dependent fashion, resulting in a lower heart rate and thus more blood to flow to the myocardium …
Tryptophan
An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit...
Approved
Nutraceutical
Withdrawn
Matched Synonyms: … (S)-α-amino-1H-indole-3-propanoic acid ... (S)-alpha-Amino-beta-(3-indolyl)-propionic acid ... (S)-Tryptophan …
Matched Iupac: … (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid …
Matched Description: … It is a precursor of indole alkaloids in plants. ... It can be a precursor to niacin, albeit inefficiently, in mammals. ... It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). …
Matched Mixtures name: … AMINOACIDI S BIOINDUSTRIA L.I.M. ... AMINOMIX 3 SOLÜSYON, 1000 ML ... AMINOMIX 3 SOLÜSYON, 2000 ML …
Matched Iupac: … (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid …
Matched Description: … It is a precursor of indole alkaloids in plants. ... It can be a precursor to niacin, albeit inefficiently, in mammals. ... It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). …
Matched Mixtures name: … AMINOACIDI S BIOINDUSTRIA L.I.M. ... AMINOMIX 3 SOLÜSYON, 1000 ML ... AMINOMIX 3 SOLÜSYON, 2000 ML …
Adenosine
The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Synonyms: … (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Iupac: … (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Mixtures name: … Dr.Different VITALIFT A Eye and Neck ... GD11 Rx SCM S ... S ALPHA 30 Skin …
Matched Products: … JUVEHEAL A Ampoule ... JEVEHEAL A Ampoule ... Dr.Different VITALIFT A …
Matched Iupac: … (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Mixtures name: … Dr.Different VITALIFT A Eye and Neck ... GD11 Rx SCM S ... S ALPHA 30 Skin …
Matched Products: … JUVEHEAL A Ampoule ... JEVEHEAL A Ampoule ... Dr.Different VITALIFT A …
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