| DB00465 | Ketorolac | An NSAID used to treat moderate to severe pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders, and headaches. |
| DB00586 | Diclofenac | An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. |
| DB00712 | Flurbiprofen | An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. |
| DB00963 | Bromfenac | An NSAID used to treat postoperative pain and inflammation of the eye. |
| DB06802 | Nepafenac | An ophthalmic NSAID used for the symptomatic treatment of pain and inflammation associated with cataract surgery. |
| DB00328 | Indomethacin | A nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants. |
| DB00461 | Nabumetone | An NSAID used to treat osteoarthritis and rheumatoid arthritis. |
| DB00469 | Tenoxicam | An anti inflammatory analgesic used to treat mild to moderate pain as well as the signs and symptoms of rheumatoid arthritis and osteoarthritis. |
| DB00482 | Celecoxib | An NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis. |
| DB00500 | Tolmetin | An NSAID used to treat acute flares of various painful conditions and used for the long term management of osteoarthritis, rheumatoid arthritis, and juvenile arthritis. |
| DB00533 | Rofecoxib | A COX-2 inhibitor NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, primary dysmenorrhea, and migraine attacks. |
| DB00554 | Piroxicam | An NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis. |
| DB00573 | Fenoprofen | An anti-inflammatory analgesic used to treat mild to moderate pain in addition to the signs and symptoms of rheumatoid arthritis and osteoarthritis. |
| DB00580 | Valdecoxib | A COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea. |
| DB00605 | Sulindac | An NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis. |
| DB00749 | Etodolac | An NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain. |
| DB00784 | Mefenamic acid | An NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea. |
| DB00788 | Naproxen | An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain. |
| DB00795 | Sulfasalazine | An anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis. |
| DB00812 | Phenylbutazone | An NSAID used to treat backache and ankylosing spondylitis. |
| DB00814 | Meloxicam | An NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics. |
| DB00821 | Carprofen | For use as a pain reliever in the treatment of joint pain and post-surgical pain. |
| DB00861 | Diflunisal | An NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis. |
| DB00870 | Suprofen | An NSAID used to prevent pupil constriction in ocular surgery. |
| DB00936 | Salicylic acid | An acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. |
| DB00939 | Meclofenamic acid | An NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis. |
| DB00945 | Acetylsalicylic acid | A salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events. |
| DB00991 | Oxaprozin | An NSAID used to treat osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis. |
| DB01009 | Ketoprofen | An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain. |
| DB01014 | Balsalazide | An aminosalicylate used to treat ulcerative colitis. |
| DB01050 | Ibuprofen | An NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation. |
| DB01250 | Olsalazine | An anti-inflammatory agent used in the treatment of inflammatory bowel disease and ulcerative colitis. |
| DB01283 | Lumiracoxib | For the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults. |
| DB01397 | Magnesium salicylate | An NSAID analgesic used in the symptomatic relief of mild to moderate muscular pain. |
| DB01399 | Salsalate | A nonsteroidal anti-inflammatory agent used in the symptomatic relief of rheumatoid arthritis, osteoarthritis and related rheumatic disorders. |
| DB01401 | Choline magnesium trisalicylate | Choline magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults. |
| DB01435 | Antipyrine | An antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine. |
| DB01600 | Tiaprofenic acid | A nonsteroidal anti-inflammatory (NSAID) used to manage inflammation and analgesia associated with rheumatoid arthritis and osteoarthritis. |
| DB01628 | Etoricoxib | For the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. |
| DB03585 | Oxyphenbutazone | A nonsteroidal anti-inflammatory drug (NSAID) no longer commonly used for the symptomatic relief of musculoskeletal pain. |
| DB04552 | Niflumic acid | Used in the treatment of rheumatoid arthritis. |
| DB04743 | Nimesulide | For the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. |
| DB04812 | Benoxaprofen | The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets... |
| DB04817 | Metamizole | Used in the past as a powerful painkiller and fever reducer. |
| DB04828 | Zomepirac | Zomepirac was indicated for the management of mild to severe pain. |
| DB06725 | Lornoxicam | For the treatment of acute mild to moderate pain, as well as pain and inflammation of the joints caused by certain types of rheumatic diseases. |
| DB06736 | Aceclofenac | Aceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. |
| DB06737 | Zaltoprofen | A non-steroidal anti-inflammatory drug approved for use in Japan in 1993. |
| DB07402 | Azapropazone | Not Available |
| DB07477 | Felbinac | Not Available |
| DB08439 | Parecoxib | A selective COX-2 inhibitor and NSAID used for the short-term management of perioperative pain. |
| DB08797 | Salicylamide | Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin.... |
| DB08940 | Kebuzone | Kebuzone (also known as ketophenylbutazone ) is a non-steroidal anti-inflammatory drug. |
| DB08942 | Isoxicam | Isoxicam is a non-steroidal anti-inflammatory drug that is not marketed in the United States. |
| DB08951 | Indoprofen | A drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide. |
| DB08955 | Ibuproxam | Ibuproxam is a non steroidal anti-inflammatory drug (NSAID). |
| DB08976 | Floctafenine | An anti-inflammatory analgesic used to manage mild to moderate acute pain. |
| DB08981 | Fenbufen | Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is... |
| DB08984 | Etofenamate | Etofenamate is used to treat muscle and joint paint. It is a non-steroidal anti-inflammatory drug (NSAID). |
| DB08991 | Epirizole | Epirizole is an oral nonsteroidal anti-inflammatory drug (NSAID) used for muscle and joint pain. |
| DB09212 | Loxoprofen | Loxoprofen is non-steroidal anti-inflammatory medication (NSAID) indicated for pain and inflammation related to musculoskeletal and joint disorders. In addition to its effects on pain, it is an antipyretic and anti-inflammatory... |
| DB09215 | Droxicam | Droxicam is an NSAID previously used for the treatment of inflammation and rheumatoid arthritis . |
| DB09216 | Tolfenamic acid | In the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults. |
| DB09218 | Clonixin | Indicated for use in the management of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. |
| DB09288 | Propacetamol | Propacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy. |
| DB11466 | Tepoxalin | Tepoxalin is a nonsteroidal anti-inflammatory drug approved for veterinary use in the United States and many other countries. It is primarily used to reduce inflammation and relief of pain caused... |
| DB11518 | Flunixin | Flunixin is a non-steroidal anti-inflammatory drug for use in pigs, cattle and horses. It exerts analgesic and antipyretic effects. This drug is often prepared for use in meglumine salt form.... |
| DB12545 | Indobufen | Indobufen has been used in trials studying the supportive care and prevention of Atrial Fibrillation. |
| DB13001 | Tinoridine | Tinoridine is under investigation in clinical trial NCT01224756 (Efficacy of Tinoridine in Treating Pain and Inflammation in Adults). |
| DB13167 | Alclofenac | Alclofenac is indicated in rheumatology, in particular for the treatment of rheumatoid arthritis, ankylosing spondylitis and, as an analgesic, in painful arthritic pathologies. |
| DB13217 | Fentiazac | Not Annotated |
| DB13232 | Suxibuzone | Not Annotated |
| DB13286 | Bumadizone | Bumadizone has been approved for use in Germany and Austria, it is a drug with anti-inflammatory, antipyretic, and analgesic properties, and was marketed for the treatment of both rheumatoid arthritis... |
| DB13314 | Alminoprofen | Alminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid class of chemical substances. |
| DB13317 | Flunoxaprofen | Not Annotated |
| DB13346 | Bufexamac | An NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses. |
| DB13364 | Feprazone | Not Annotated |
| DB13371 | Difenpiramide | Not Annotated |
| DB13407 | Nifenazone | Not Annotated |
| DB13432 | Lonazolac | Not Annotated |
| DB13481 | Tenidap | Not Annotated |
| DB13501 | Bendazac | Prior to the withdrawal of bendazac from various international regions of use due to concerns for hepatotoxicity [A39891, A39892, A39893, L4778] the chemical had demonstrated potential usefulness predominantly as the... |
| DB13514 | Pranoprofen | Not Annotated |
| DB13524 | Propyphenazone | Not Annotated |
| DB13527 | Proglumetacin | Not Annotated |
| DB13538 | Guacetisal | Not Annotated |
| DB13544 | Ethenzamide | Not Annotated |
| DB13612 | Carbaspirin calcium | Not Annotated |
| DB13629 | Mofebutazone | Not Annotated |
| DB13649 | Proquazone | Not Annotated |
| DB13657 | Benorilate | Not Annotated |
| DB13722 | Pirprofen | Not Annotated |
| DB13783 | Acemetacin | Acemetacin is not FDA, Canada or EMA approved, but in the countries where it is marketed it is indicated for the symptomatic treatment of pain and swelling in acute inflammation... |
| DB13860 | Imidazole salicylate | Not Annotated |
| DB09084 | Benzydamine | A locally-acting NSAID indicated for the symptomatic relief of pain in acute sore throat and for the symptomatic relief of oropharyngeal mucositis caused by radiation therapy. |
| DB00159 | Icosapent | A polyunsaturated fatty acid, usually found in fish oils, that is used in many supplements. |
| DB01419 | Antrafenine | Antrafenine is used as an anti-inflammatory and analgesic agent for the relief of mild to moderate pain. |
| DB09213 | Dexibuprofen | For more information, refer to ibuprofen. |
| DB11079 | Trolamine salicylate | A medication used to relieve minor aches and pains of the muscles and joints. |
| DB05095 | Cimicoxib | Investigated for use/treatment in depression. |
| DB11455 | Robenacoxib | Robenacoxib is a non-steroidal anti-inflammatory drug used in veterinary medicine for the relief of pain and inflammation in cats and dogs. |
| DB01424 | Aminophenazone | Formerly widely used as an antipyretic and analgesic in rheumatism, neuritis, and common colds. Currently used to measure total body water. |
| DB00244 | Mesalazine | An aminosalicylate drug used to treat mild to moderate active ulcerative colitis and also to maintain remission once achieved. |
| DB14059 | SC-236 | SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , . |
| DB14060 | NS-398 | NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases. |
| DB09217 | Firocoxib | Used for the treatment of pain inflammation and fever in horses and dogs. |
| DB12445 | Nitroaspirin | Nitroaspirin has been investigated for the treatment of Intermittent Claudication. |
| DB09285 | Morniflumate | Morniflumate is indicated for the treatment of inflammatory conditions affecting the airways, ENT system, urogenital tract and bone and joint systems in adults. In Italy, morniflumate is also indicated for... |
| DB09295 | Talniflumate | Talnifumate is a phthalidyl ester of nifumic acid, which has potent analgesic and anti-inflammatory effects and is widely used to treat inflammatory disorders, such as rheumatoid arthritis and osteoarthritis ,... |
| DB09214 | Dexketoprofen | For short-term treatment of mild to moderate pain, including dysmenorrhoea, musculoskeletal pain and toothache . |
| DB02224 | Taxifolin | Not Available |
| DB12480 | Betulinic Acid | Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome. |
| DB12610 | Ebselen | Ebselen has been investigated for the treatment and basic science of Meniere's Disease, Type 2 Diabetes Mellitus, and Type 1 Diabetes Mellitus. |
| DB14938 | Flurbiprofen axetil | Flurbiprofen axetil is under investigation in clinical trial NCT02043366 (Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients). |
| DB12399 | Polmacoxib | Polmacoxib has been used in trials studying the treatment of Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis, Knee, Localized Primary Osteoarthritis of Hip, and Localized Primary Osteoarthritis of Knee. |
| DB04725 | Licofelone | For the management of osteoarthritis. |