Name
Diuretics
Accession Number
DBCAT000542
Description

Agents that promote the excretion of urine through their effects on kidney function.

ATC Classification
Drugs
DrugDrug Description
TorasemideA diuretic used to treat hypertension and edema associated with heart failure, renal failure, or liver disease.
TriamtereneA potassium-sparing diuretic used in the treatment of edema and in the management of hypertension.
SpironolactoneAn aldosterone receptor antagonist used for the treatment of hypertension, hyperaldosteronism, edema due to various conditions, hirsutism (off-label) and hypokalemia.
AmilorideA pyrizine compound used to treat hypertension and congestive heart failure.
EplerenoneAn aldosterone receptor antagonist used to improve survival of patients with symptomatic heart failure and to reduce blood pressure.
Etacrynic acidA diuretic used to treat ascites and edema in congestive heart failure, liver cirrhosis, and renal disease.
QuinethazoneUsed to treat hypertension.
PiretanidePiretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine...
Tienilic acidFor the treatment of hypertension.
Canrenoic acidCanrenoic acid (as the salt potassium canrenoate) is an aldosterone antagonist. Like spironolactone, it is a prodrug, which is metabolized to canrenone in the body.
CanrenoneCanrenone has been used in trials studying the diagnostic of Heart Failure.
CicletanineCicletanine is under investigation for the treatment of Diabetes, Hypokalemia, Hyponatremia, and Arterial Hypertension.
MefrusideNot Annotated
CyclopenthiazideCyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients...
FenquizoneNot Annotated
ClopamideClopamide is an oral diuretic agent with antihypertensive activity. Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure.
MuzolimineNot Annotated
XipamideNot Annotated
MethyclothiazideA diuretic drug used to treat hypertension and edema caused by heart failure, renal conditions, treatment with corticosteroids, and estrogen therapy.
CyclothiazideCyclothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either...
FurosemideA loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension.
IndapamideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure.
BumetanideA sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome.
HydrochlorothiazideA thiazide diuretic used to treat edema associated with a number of conditions, and hypertension.
TrichlormethiazideUsed in the treatment of oedema (including that associated with heart failure) and hypertension.
ChlorthalidoneA diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions.
EthoxzolamideFor use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy.
BendroflumethiazideA diuretic used to suppress lactation and to treat hypertension and edema.
MetolazoneA thiazide-like diuretic used to treat hypertension.
MethazolamideA carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma.
MannitolA sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, and to measure glomerular filtration rate.
HydroflumethiazideA thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis.
AcetazolamideA carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma.
ChlorothiazideA thiazide diuretic used to treat hypertension and edema in congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy.
PolythiazideA thiazide diuretic used in the management of hypertension and treatment of edema.
DrospirenoneA progestin used in oral contraceptive pills for the prevention of pregnancy and other conditions.
UlaritideInvestigated for use/treatment in congestive heart failure.
AzosemideAzosemide is a loop diuretic used to treat hypertension, edema, and ascites.
Potassium citrateAn agent used to manage renal tubular acidosis, hypocitraturic calcium oxalate nephrolithiasis, and uric acid lithiasis with or without calcium stones.
EfonidipineFor the treatment of hypertension.
IsosorbideA vasodilator used for the prevention and treatment of angina pectoris due to coronary artery disease.
RolofyllineRolofylline is under clinical development by pharmaceutical company NovaCardia for the treatment of congestive heart failure.
SpiradolineSpiradoline has been investigated for the basic science of Bipolar Depression.
IbopamineNot Annotated
ConivaptanAn antidiuretic hormone inhibitor used to raise serum sodium levels.
Potassium cationPotassium is used to regulate hypokalemia as a primary condition or secondary to other medical conditions.
Theobrominetheobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension.
TolvaptanA selective vasopressin V2-receptor antagonist to slow kidney function decline in patients at risk for rapidly progressing autosomal dominant polycystic kidney disease (ADPKD). Also used to treat hypervolemic and euvolemic hyponatremia.
MersalylElevated blood pressure, edema [L1577, L1585].
MeticraneMeticrane is a diuretic medication. It has been marketed in Japan under the trade name Arresten and is used to lower blood pressure .
MebutizideNot Annotated
ClorexoloneNot Annotated
ClofenamideNot Annotated
EpitizideEpitizide is an agent, commonly found in combination triamterene, used to produce diuresis.
BromotheophyllineBromotheophylline is used as a diuretic and also, in combination with DB00316, it is used for the relief of temporary water weight gain, bloating, swelling and full feeling associated with...
BenzthiazideFor the treatment of high blood pressure and management of edema.
DorzolamideA carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma.
BrinzolamideA carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
DiclofenamideA carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure.
DapagliflozinA sodium-glucose cotransporter 2 inhibitor used in the management of type 2 diabetes mellitus.
CanagliflozinA sodium-glucose co-transporter 2 (SGLT2) inhibitor used to manage hyperglycemia in type 2 diabetes mellitus (DM). Also used to reduce the risk of major cardiovascular events in patients with established cardiovascular disease and type 2 DM.
EmpagliflozinA SGLT-2 inhibitor used to manage type 2 diabetes mellitus.
PotassiumA medication used to treat hypokalemic conditions and to clear the colon prior to colonoscopy.
ErtugliflozinA SGLT2 inhibitor used to treat type 2 diabetes mellitus.
ZonisamideA sulfonamide anticonvulsant used to treat partial seizures.
DiazoxideA non diuretic benzothiadiazine indicated for the management of hypoglycemia in patients who produce an excess of insulin caused by a variety of conditions.
IndisulamInvestigated for use/treatment in lung cancer.
Drugs & Drug Targets
DrugTargetType
TorasemideSolute carrier family 12 member 1target
TorasemideCytochrome P450 2C8enzyme
TorasemideCytochrome P450 2C9enzyme
TorasemideSolute carrier organic anion transporter family member 1B1transporter
TorasemideSolute carrier family 12 member 2target
TorasemideSerum albumincarrier
TriamtereneAmiloride-sensitive sodium channel subunit gammatarget
TriamtereneAmiloride-sensitive sodium channel subunit alphatarget
TriamtereneAmiloride-sensitive sodium channel subunit betatarget
TriamtereneAmiloride-sensitive sodium channel subunit deltatarget
TriamtereneCytochrome P450 1A2enzyme
SpironolactoneMineralocorticoid receptortarget
SpironolactoneCytochrome P450 2C8enzyme
SpironolactoneCanalicular multispecific organic anion transporter 1transporter
SpironolactoneP-glycoprotein 1transporter
SpironolactoneSolute carrier organic anion transporter family member 1A2transporter
SpironolactoneCytochrome P450 11B1, mitochondrialenzyme
SpironolactoneAndrogen receptortarget
SpironolactoneProgesterone receptortarget
SpironolactoneGlucocorticoid receptortarget
SpironolactoneCytochrome P450 11B2, mitochondrialtarget
SpironolactoneSteroid 17-alpha-hydroxylase/17,20 lyasetarget
Spironolactone3-oxo-5-alpha-steroid 4-dehydrogenasetarget
SpironolactoneSex hormone-binding globulintarget
SpironolactoneVoltage-dependent calcium channeltarget
SpironolactoneNuclear receptor subfamily 1 group I member 2target
SpironolactoneBile salt export pumptransporter
SpironolactoneSerum albumincarrier
Spironolactonealpha1-acid glycoproteincarrier
AmilorideAmiloride-sensitive sodium channel subunit betatarget
AmilorideAcid-sensing ion channel 1target
AmilorideAmiloride-sensitive amine oxidase [copper-containing]target
AmilorideAmiloride-sensitive sodium channel subunit alphatarget
AmilorideAmiloride-sensitive sodium channel subunit gammatarget
AmilorideSodium/hydrogen exchanger 1target
AmilorideAcid-sensing ion channel 2target
AmilorideAmiloride-sensitive sodium channel subunit deltatarget
AmilorideUrokinase-type plasminogen activatortarget
AmilorideSolute carrier family 22 member 2transporter
AmilorideSolute carrier family 22 member 4transporter
AmilorideAmiloride-sensitive amine oxidase [copper-containing]enzyme
AmilorideAmiloride-sensitive amine oxidase [copper-containing]enzyme
EplerenoneMineralocorticoid receptortarget
EplerenoneCytochrome P450 3A4enzyme
EplerenoneCytochrome P450 3A5enzyme
EplerenoneCytochrome P450 11B2, mitochondrialenzyme
Etacrynic acidSolute carrier family 12 member 1target
Etacrynic acidSodium/potassium-transporting ATPase subunit alpha-1target
Etacrynic acidGlutathione S-transferase A2enzyme
Etacrynic acidSerum albumincarrier
Etacrynic acidSolute carrier family 22 member 6transporter
Etacrynic acidLymphoid enhancer-binding factor 1target
Etacrynic acidGlutathione S-transferase Ptarget
QuinethazoneCarbonic anhydrase 1target
QuinethazoneCarbonic anhydrase 2target
QuinethazoneSolute carrier family 12 member 1target
QuinethazoneSolute carrier family 12 member 2target
QuinethazoneSolute carrier family 12 member 3target
PiretanideSolute carrier family 12 member 1target
Tienilic acidCytochrome P450 2C9enzyme
MethyclothiazideSolute carrier family 12 member 1target
MethyclothiazideCarbonic anhydrase 4target
MethyclothiazideCarbonic anhydrase 2target
MethyclothiazideCarbonic anhydrase 1target
CyclothiazideSodium/potassium-transporting ATPase subunit gammatarget
CyclothiazideCarbonic anhydrase 1target
CyclothiazideCarbonic anhydrase 2target
CyclothiazideSolute carrier family 22 member 6transporter
CyclothiazideSecreted frizzled-related protein 4target
CyclothiazideCarbonic anhydrasetarget
FurosemideSolute carrier family 12 member 1target
FurosemideSerum albumincarrier
FurosemideSolute carrier family 22 member 6transporter
FurosemideSolute carrier family 22 member 5transporter
FurosemideSolute carrier family 22 member 8transporter
FurosemideCanalicular multispecific organic anion transporter 1transporter
FurosemideSolute carrier organic anion transporter family member 2A1transporter
FurosemideSolute carrier family 22 member 11transporter
Furosemide6-phosphogluconate dehydrogenase, decarboxylatingenzyme
FurosemideCarbonic anhydrase 2target
FurosemideUDP-glucuronosyltransferase 1-1enzyme
FurosemideThyroxine-binding globulincarrier
FurosemideG-protein coupled receptor 35target
IndapamideCytochrome P450 3A4enzyme
IndapamideSolute carrier family 12 member 3target
BumetanideSolute carrier family 12 member 1target
BumetanideCystic fibrosis transmembrane conductance regulatortarget
BumetanideSolute carrier family 12 member 2target
BumetanideSolute carrier family 12 member 4target
BumetanideSolute carrier family 12 member 5target
BumetanideSodium/bile acid cotransportertransporter
BumetanideSolute carrier family 22 member 6transporter
BumetanideSolute carrier family 22 member 8transporter
BumetanideSolute carrier family 22 member 11transporter
BumetanideSolute carrier family 22 member 7transporter
BumetanideSolute carrier organic anion transporter family member 1A2transporter
BumetanideProstaglandin G/H synthase 2enzyme
HydrochlorothiazideSolute carrier family 12 member 3target
HydrochlorothiazideSolute carrier family 22 member 6transporter
HydrochlorothiazideCalcium-activated potassium channel subunit alpha-1target
HydrochlorothiazideSerum albumincarrier
HydrochlorothiazideSolute carrier family 22 member 11transporter
HydrochlorothiazideMultidrug resistance-associated protein 4transporter
HydrochlorothiazideSolute carrier family 22 member 8transporter
TrichlormethiazideSolute carrier family 12 member 3target
TrichlormethiazideSodium/potassium-transporting ATPase subunit alpha-1target
TrichlormethiazideCarbonic anhydrase 4target
TrichlormethiazideCarbonic anhydrase 2target
TrichlormethiazideCarbonic anhydrase 1target
TrichlormethiazideThiopurine S-methyltransferaseenzyme
ChlorthalidoneSolute carrier family 12 member 1target
ChlorthalidoneSerum albumincarrier
ChlorthalidoneCarbonic anhydrase 1target
EthoxzolamideCarbonic anhydrase 1target
EthoxzolamideSolute carrier family 22 member 6transporter
EthoxzolamideCarbonic anhydrase 2target
EthoxzolamideCarbonic anhydrase 4target
EthoxzolamideCarbonic anhydrase 7target
EthoxzolamideCarbonic anhydrase 3target
BendroflumethiazideSolute carrier family 12 member 3target
BendroflumethiazideCarbonic anhydrase 1target
BendroflumethiazideCarbonic anhydrase 2target
BendroflumethiazideCarbonic anhydrase 4target
BendroflumethiazideCalcium-activated potassium channel subunit alpha-1target
BendroflumethiazideThiopurine S-methyltransferaseenzyme
MetolazoneSolute carrier family 12 member 3target
MethazolamideCarbonic anhydrase 1target
MethazolamideSolute carrier family 22 member 6transporter
MethazolamideCarbonic anhydrase 4target
MethazolamideCarbonic anhydrase 2target
MethazolamideCarbonic anhydrase 7target
MethazolamideCarbonic anhydrase 3target
MannitolMannitol dehydrogenaseenzyme
HydroflumethiazideSolute carrier family 12 member 1target
HydroflumethiazideSodium/potassium-transporting ATPase subunit alpha-1target
HydroflumethiazideCarbonic anhydrase 4target
HydroflumethiazideCalcium-activated potassium channel subunit alpha-1target
HydroflumethiazideCarbonic anhydrase 2target
HydroflumethiazideCarbonic anhydrase 1target
HydroflumethiazideCarbonic anhydrase 9target
HydroflumethiazideCarbonic anhydrase 12target
HydroflumethiazideSerum albumincarrier
HydroflumethiazideSolute carrier family 22 member 6transporter
HydroflumethiazideSolute carrier family 22 member 8transporter
HydroflumethiazideCarbonic anhydrase 7target
AcetazolamideCarbonic anhydrase 1target
AcetazolamideAquaporin-1target
AcetazolamideCarbonic anhydrase 14target
AcetazolamideSolute carrier family 22 member 6transporter
AcetazolamideCarbonic anhydrase 2target
AcetazolamideCarbonic anhydrase 3target
AcetazolamideCarbonic anhydrase 4target
AcetazolamideCytochrome P450 3A4enzyme
AcetazolamideCarbonic anhydrase 7target
AcetazolamideCarbonic anhydrase 12target
ChlorothiazideSolute carrier family 12 member 3target
ChlorothiazideCarbonic anhydrase 1target
ChlorothiazideCarbonic anhydrase 2target
ChlorothiazideSolute carrier family 22 member 6transporter
PolythiazideSolute carrier family 12 member 3target
PolythiazideSolute carrier family 22 member 6transporter
PolythiazideSolute carrier family 22 member 8transporter
PolythiazideSerum albumincarrier
DrospirenoneProgesterone receptortarget
DrospirenoneMineralocorticoid receptortarget
DrospirenoneAndrogen receptortarget
DrospirenoneProstaglandin G/H synthase 2enzyme
DrospirenoneSerum paraoxonase/arylesterase 1enzyme
DrospirenoneGlucocorticoid receptortarget
DrospirenoneCytochrome P450 3A4enzyme
UlaritideAtrial natriuretic peptide receptor 1target
EfonidipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
EfonidipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
EfonidipineCytochrome P450 3A4enzyme
IsosorbideApoptosis regulator Bcl-2target
IsosorbideBcl-2-like protein 1target
IsosorbideInduced myeloid leukemia cell differentiation protein Mcl-1target
RolofyllineAdenosine receptor A1target
ConivaptanVasopressin V1a receptortarget
ConivaptanVasopressin V2 receptortarget
ConivaptanCytochrome P450 3A4enzyme
ConivaptanP-glycoprotein 1transporter
Potassium cationSodium/potassium-transporting ATPase subunit alpha-1target
TheobromineCytochrome P450 1A2enzyme
TheobromineCytochrome P450 2E1enzyme
TheobromineAdenosine receptor A1target
TheobromineAdenosine receptor A2atarget
TheobrominecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
TolvaptanVasopressin V2 receptortarget
TolvaptanCytochrome P450 3A4enzyme
TolvaptanP-glycoprotein 1transporter
TolvaptanVasopressin V1a receptortarget
MersalylAlkaline phosphatase, tissue-nonspecific isozymetarget
MersalylAquaporin-1target
MersalylMonocarboxylate transporter 1target
MersalylInter-alpha-trypsin inhibitor heavy chain H1enzyme
MersalylPhosphoenolpyruvate carboxykinase, cytosolic [GTP]enzyme
BromotheophyllineCytochrome P450 1A2enzyme
BenzthiazideSolute carrier family 12 member 3target
BenzthiazideCarbonic anhydrase 1target
BenzthiazideCarbonic anhydrase 2target
BenzthiazideCarbonic anhydrase 4target
BenzthiazideCarbonic anhydrase 9target
BenzthiazideCarbonic anhydrase 12target
BenzthiazideCarbonic anhydrasetarget
DorzolamideCarbonic anhydrase 2target
DorzolamideCarbonic anhydrase 1target
DorzolamideCarbonic anhydrase 4target
DorzolamideCytochrome P450 2C9enzyme
DorzolamideCarbonic anhydrase 3target
DorzolamideCytochrome P450 2B1enzyme
DorzolamideCytochrome P450 2E1enzyme
DorzolamideCytochrome P450 3A2enzyme
BrinzolamideCarbonic anhydrase 1target
BrinzolamideCarbonic anhydrase 2target
BrinzolamideCytochrome P450 3A4enzyme
BrinzolamideCarbonic anhydrase 5A, mitochondrialtarget
BrinzolamideCarbonic anhydrase 4target
BrinzolamideCarbonic anhydrase 3target
DiclofenamideCarbonic anhydrase 1target
DiclofenamideCarbonic anhydrase 4target
DiclofenamideCarbonic anhydrase 2target
DiclofenamideCarbonic anhydrase 7target
DiclofenamideCarbonic anhydrase 3target
DapagliflozinSodium/glucose cotransporter 2target
DapagliflozinCytochrome P450 1A1enzyme
DapagliflozinCytochrome P450 1A2enzyme
DapagliflozinCytochrome P450 2A6enzyme
DapagliflozinCytochrome P450 2C9enzyme
DapagliflozinCytochrome P450 2D6enzyme
DapagliflozinCytochrome P450 3A4enzyme
DapagliflozinUDP-glucuronosyltransferase 1-9enzyme
DapagliflozinUDP-glucuronosyltransferase 2B4enzyme
DapagliflozinUDP-glucuronosyltransferase 2B7enzyme
DapagliflozinP-glycoprotein 1transporter
CanagliflozinUDP-glucuronosyltransferase 1-9enzyme
CanagliflozinUDP-glucuronosyltransferase 2B4enzyme
CanagliflozinCytochrome P450 3A4enzyme
CanagliflozinSodium/glucose cotransporter 2target
CanagliflozinP-glycoprotein 1transporter
CanagliflozinCanalicular multispecific organic anion transporter 1transporter
CanagliflozinAlpha-1-acid glycoprotein 1carrier
CanagliflozinATP-binding cassette sub-family G member 2transporter
EmpagliflozinSodium/glucose cotransporter 2target
PotassiumSodium/potassium-transporting ATPase subunit alpha-1target
PotassiumSodium/potassium-transporting ATPase subunit alpha-1transporter
PotassiumSolute carrier family 12 member 1transporter
ErtugliflozinUDP-glucuronosyltransferase 1-9enzyme
ErtugliflozinUDP-glucuronosyltransferase 2B7enzyme
ErtugliflozinSodium/glucose cotransporter 2target
ErtugliflozinP-glycoprotein 1transporter
ErtugliflozinATP-binding cassette sub-family G member 2transporter
ErtugliflozinSerum albumincarrier
ErtugliflozinUDP-glucuronosyltransferase 1-1enzyme
ErtugliflozinUDP-glucuronosyltransferase 1-4enzyme
ZonisamideSodium channel protein type 1 subunit alphatarget
ZonisamideCarbonic anhydrase 1target
ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
ZonisamideCytochrome P450 3A4enzyme
ZonisamideAldehyde oxidaseenzyme
ZonisamideAmine oxidase [flavin-containing] Btarget
ZonisamideCarbonic anhydrase 2target
ZonisamideCarbonic anhydrase 3target
ZonisamideCarbonic anhydrase 4target
ZonisamideCarbonic anhydrase 5A, mitochondrialtarget
ZonisamideCarbonic anhydrase 5B, mitochondrialtarget
ZonisamideCarbonic anhydrase 6target
ZonisamideCarbonic anhydrase 7target
ZonisamideCarbonic anhydrase-related proteintarget
ZonisamideCarbonic anhydrase 9target
ZonisamideCarbonic anhydrase-related protein 10target
ZonisamideCarbonic anhydrase-related protein 11target
ZonisamideCarbonic anhydrase 12target
ZonisamideCarbonic anhydrase 13target
ZonisamideCarbonic anhydrase 14target
ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Htarget
ZonisamideVoltage-dependent T-type calcium channel subunit alpha-1Itarget
ZonisamideSodium channel protein type 2 subunit alphatarget
ZonisamideSodium channel protein type 3 subunit alphatarget
ZonisamideSodium channel protein type 4 subunit alphatarget
ZonisamideSodium channel protein type 5 subunit alphatarget
ZonisamideSodium channel protein type 9 subunit alphatarget
ZonisamideSodium channel protein type 11 subunit alphatarget
ZonisamideSodium channel subunit beta-1target
ZonisamideSodium channel subunit beta-2target
ZonisamideSodium channel subunit beta-3target
ZonisamideSodium channel subunit beta-4target
ZonisamideAmine oxidase [flavin-containing] Atarget
ZonisamideCytochrome P450 2C19enzyme
ZonisamideUDP-glucuronosyltransferase 1-1enzyme
ZonisamideCytochrome P450 3A5enzyme
ZonisamideP-glycoprotein 1transporter
DiazoxideCarbonic anhydrase 1target
DiazoxideCarbonic anhydrase 2target
DiazoxideCalcium-activated potassium channel subunit alpha-1target
DiazoxideSodium/potassium-transporting ATPase subunit alpha-1target
DiazoxideATP-sensitive inward rectifier potassium channel 11target
DiazoxideGlutamine synthetaseenzyme
IndisulamCytochrome P450 2C9enzyme
IndisulamCytochrome P450 3A4enzyme
IndisulamCytochrome P450 2E1enzyme
IndisulamCytochrome P450 2D6enzyme