Sugar Acids

MONOSACCHARIDES and other sugars that contain one or more carboxylic acid moieties.
DrugDrug NameDrug Indication
DB00126Ascorbic acidUsed to treat vitamin C deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. It has also been suggested to be an effective antiviral agent.
DB00558ZanamivirFor the prevention and treatment of influenza A and B.
DB01157TrimetrexateFor use, with concurrent leucovorin administration (leucovorin protection), as an alternative therapy for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients, including patients with the acquired immunodeficiency syndrome (AIDS). Also used to treat several types of cancer including colon cancer.
DB020766-phospho-D-gluconic acidNot Available
DB034892-Keto-3-DeoxygluconateNot Available
DB04564GluconolactoneNot Available
DB05630Sodium stibogluconateFor the treatment of various types of a protozoal infection called leishmaniasis, which may result from sandfly bites in tropical and temperate parts of the world. Also investigated for use/treatment in cancer/tumors (unspecified) and solid tumors.
DB08830Dehydroascorbic acidThere is no approved indication for dehydroascorbic acid, but it has potential therapeutic use in patients with certain viruses and ischemic stroke.
DB09146Iron saccharateIron sucrose is elemental iron as an injection. It replenishes body iron stores in patients with iron deficiency.
DB09459L-tartaric acidTartaric Acid is primarily indicated in conditions like Antiscorbutic, Antiseptic.
DB11126Calcium gluconateOral calcium salts are used as dietary supplemental therapy for person who may not get enough calcium in their regular diet. Calcium gluconate is used as a cardioprotective agent in high blood potassium. Calcium gluconate is the antidote for magnesium sulfate toxicity.
DB11141Manganese gluconateManganese gluconate is currently only available in combination products. It is indicated for the prophylactic or nutritional supplementation of [DB06757] [FDA Label].
DB11248Zinc gluconateZinc gluconate is mainly indicated in conditions like zinc deficiency, and can also be administered in adjunctive therapy as an alternative drug of choice in diarrhea [L2088].
DB11335Ascorbyl glucosideNot Available
DB11888Laninamivir octanoateNot Available
DB12791LaninamivirNot Available
DB13180Gluconic AcidFor use as part of electrolyte supplementation in total parenteral nutrition [FDA Label].
DB13518Alginic acidIndicated for the management of gastric reflux, reflux oesophagitis, hiatus hernia, heartburn (including heartburn of pregnancy) and similar gastric distress [F46].
DB13590Calcium pangamateNot Available
DB13615MifamurtideIndicated in children, adolescents and young adults for the treatment of high-grade, resectable, non-metastatic osteosarcoma after macroscopically complete surgical resection, typically in combination with post-operative multi-agent chemotherapy [L1203].
DB13707Sodium tartrate It acts as an emulsifier and pH control agent in food products [L2590], [L2598]. In the laboratory, it is used while performing the Karl Fischer equation, which is used to determine the water content of various substances [F18], [L2590].
DB13749Magnesium gluconateMagnesium gluconate is a mineral supplement which is used to prevent and treat low levels of magnesium. Magnesium is very important for the normal physiologic functioning of cells, nerves, muscles, bones, and the heart. Generally, a well-balanced diet provides the necessary amounts of magnesium for homeostasis. However, certain conditions causing chronic magnesium deficiency may decrease levels of magnesium. These conditions include treatment with diuretics, a poor diet, alcoholism, or other medical conditions (e.g., severe diarrhea/vomiting, stomach/intestinal absorption problems, poorly controlled diabetes) [L2600].
DB14483Calcium ascorbateNot Available
DB03603Glucaric acidNot Available
DB045103-phospho-D-glyceric acidNot Available
DB14932ColeneuramideNot Available
DrugDrug NameTargetType
DB00126Ascorbic acidProlyl 4-hydroxylase subunit alpha-1target
DB00126Ascorbic acidSolute carrier family 23 member 1target
DB00126Ascorbic acidProcollagen-lysine,2-oxoglutarate 5-dioxygenase 1target
DB00126Ascorbic acidHyaluronate lyasetarget
DB00126Ascorbic acidDNAtarget
DB00126Ascorbic acidXylose isomerasetarget
DB00126Ascorbic acidProcollagen-lysine,2-oxoglutarate 5-dioxygenase 2target
DB00126Ascorbic acidPhytanoyl-CoA dioxygenase, peroxisomaltarget
DB00126Ascorbic acidProcollagen-lysine,2-oxoglutarate 5-dioxygenase 3target
DB00126Ascorbic acidGamma-butyrobetaine dioxygenasetarget
DB00126Ascorbic acidDopamine beta-hydroxylasetarget
DB00126Ascorbic acidPeptidyl-glycine alpha-amidating monooxygenasetarget
DB00126Ascorbic acidProlyl 3-hydroxylase 1target
DB00126Ascorbic acid2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2target
DB00126Ascorbic acidAlpha-ketoglutarate-dependent dioxygenase alkB homolog 2target
DB00126Ascorbic acidProlyl 3-hydroxylase 2target
DB00126Ascorbic acidProlyl 3-hydroxylase 3target
DB00126Ascorbic acid2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1target
DB00126Ascorbic acidEgl nine homolog 2target
DB00126Ascorbic acidAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3target
DB00126Ascorbic acidLysine-specific demethylase 5Dtarget
DB00126Ascorbic acidEgl nine homolog 1target
DB00126Ascorbic acidEgl nine homolog 3target
DB00126Ascorbic acidTrimethyllysine dioxygenase, mitochondrialtarget
DB00126Ascorbic acidTransmembrane prolyl 4-hydroxylasetarget
DB00126Ascorbic acidLactase-phlorizin hydrolasetarget
DB00126Ascorbic acidSolute carrier family 23 member 1transporter
DB00558ZanamivirNeuraminidasetarget
DB00558ZanamivirNeuraminidasetarget
DB00558ZanamivirSialidase-2target
DB01157TrimetrexateDihydrofolate reductasetarget
DB020766-phospho-D-gluconic acid6-phosphogluconate dehydrogenase, decarboxylatingtarget
DB020766-phospho-D-gluconic acidGlucose-6-phosphate isomerasetarget
DB020766-phospho-D-gluconic acidThermoresistant gluconokinasetarget
DB034892-Keto-3-Deoxygluconate2-keto-3-deoxy-gluconate kinasetarget
DB04564GluconolactoneLactase-phlorizin hydrolasetarget
DB05630Sodium stibogluconateDNA topoisomerase 1target
DB08830Dehydroascorbic acidSolute carrier family 2, facilitated glucose transporter member 1transporter
DB09146Iron saccharateHemoglobin subunit alphatarget
DB09146Iron saccharateSerotransferrincarrier
DB09459L-tartaric acidGalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1enzyme
DB09459L-tartaric acidHypoxia-inducible factor 1-alpha inhibitorenzyme
DB13615MifamurtideToll-like receptor 4target
DB13615MifamurtideNucleotide-binding oligomerization domain-containing protein 2target
DB13749Magnesium gluconateHexokinaseenzyme
DB13749Magnesium gluconateCreatine kinase B-typeenzyme
DB13749Magnesium gluconateTyrosine-protein kinase ABL1enzyme
DB13749Magnesium gluconateATP synthase subunit delta, mitochondrialenzyme
DB13749Magnesium gluconateAdenylate cyclase type 1enzyme
DB13749Magnesium gluconateGuanylate cyclase soluble subunit alpha-2enzyme
DB13749Magnesium gluconate6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1enzyme
DB13749Magnesium gluconatePhosphoribosylpyrophosphate synthetaseenzyme
DB13749Magnesium gluconateSodium/potassium-transporting ATPase subunit alpha-1enzyme
DB03603Glucaric acidGlucarate dehydratasetarget
DB045103-phospho-D-glyceric acidTriosephosphate isomerasetarget
DB045103-phospho-D-glyceric acid2,3-bisphosphoglycerate-independent phosphoglycerate mutasetarget
DB045103-phospho-D-glyceric acidPhosphoglycerate mutase 2target
DB045103-phospho-D-glyceric acidTriosephosphate isomerasetarget
DB045103-phospho-D-glyceric acidPhosphoglycerate kinase 1target
DB045103-phospho-D-glyceric acidBifunctional PGK/TIMtarget