Vitamin C

Identification

Name
Vitamin C
Accession Number
DB00126  (NUTR00001, APRD00084, EXPT00568, DB11167, DB11316, DB11170, DB09541, DB11317)
Type
Small Molecule
Groups
Approved, Nutraceutical
Description

A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.

Structure
Thumb
Synonyms
  • acide ascorbique
  • ácido ascórbico
  • acidum ascorbicum
  • acidum ascorbinicum
  • Ascorbate
  • Ascorbic Acid
  • Ascorbicap
  • Ascorbinsäure
  • L-(+)-ascorbic acid
  • L-Ascorbate
  • L-Ascorbic Acid
External IDs
E 300 / E-300 / E300 / FEMA NO. 2109 / INS NO.300 / INS-300 / NSC-218455 / NSC-33832
Product Ingredients
IngredientUNIICASInChI Key
Calcium ascorbate183E4W213W Not AvailableNot applicable
Magnesium ascorbate0N1G678593 Not AvailableNot applicable
Niacinamide ascorbateJTL8B7TVW7 Not AvailableNot applicable
Sodium ascorbateS033EH8359 134-03-2PPASLZSBLFJQEF-RXSVEWSESA-M
Zinc ascorbate9TI35313XW Not AvailableNot applicable
Product Images
Approved Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Ascor L 500Solution500 mgIntramuscular; Intravenous; SubcutaneousMcguff Pharmaceuticals Inc2014-09-11Not applicableCanada
Ascorbic Acid Inj 500mg/mlSolution500 mgIntramuscular; IntravenousKripps Pharmacy Ltd.1987-12-31Not applicableCanada
Ascorbic Acid Injection USP 500 mg/mlSolution500 mgIntramuscular; Intravenous; SubcutaneousAlveda Pharmaceuticals Inc2014-10-28Not applicableCanada
B.G. Plus FormulaTablet166.7 mgOralAbundance Naturally LtdNot applicableNot applicableCanada
Betac Ascorbic Acid Injection, USP 500mg/mlSolution500 mgIntramuscular; Intravenous; SubcutaneousBioniche Pharma (Canada) Ltd2002-10-312006-08-04Canada
Cataplex C Tab 5.7mgTablet5.7 mgOralStandard Process Inc.Not applicableNot applicableCanada
Chew C Berry Tablets - 125mgTablet125 mgOralMorter HealthsystemNot applicableNot applicableCanada
Chewable C Vitamin 300 Mg With AcerolaTablet300 mgOralLeiner Health ProductsNot applicableNot applicableCanada
Chewable Vitamin C 250 mgTablet250 mgOralLeiner Health ProductsNot applicableNot applicableCanada
Mega C Acid Inj 500mg/mlLiquid500 mgIntramuscular; Intravenous; SubcutaneousMerit Pharmaceuticals1984-12-312016-08-22Canada
Mega-C-sodium Inj 250mg/mlSolution250 mgIntravenousKripps Pharmacy Ltd.1981-12-31Not applicableCanada
Timed Release Vitamin C Tablet With BioflavanoidsTablet, extended release1000 mgOralChampion NutritionNot applicableNot applicableCanada
Vitamin CLiquid250 mgIntramuscular; IntravenousSandoz Canada Incorporated1989-12-31Not applicableCanada
Vitamin CSolution500 mgIntramuscular; Intravenous; SubcutaneousMylan Pharmaceuticals2002-05-29Not applicableCanada
Vitamin C 500mg TabletsTablet500 mgOralAshbury Research CorporationNot applicableNot applicableCanada
Vitamin C PowderPowder1250 mgOralSelf Health Resource CentreNot applicableNot applicableCanada
Vitamin C Tab USPTablet100 mgOralStandard Process Inc.Not applicableNot applicableCanada
Approved Generic Prescription Products
Not Available
Approved Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
AcerotabTablet100 mgOralFrega Inc.1979-12-312008-02-13Canada
Acti-scorb 1000 Caplet 1000mgTablet1 gOralActi Form Ltd.1991-12-312005-03-21Canada
Acti-scorb 500 Caplet 500mgTablet500 mgOralActi Form Ltd.1991-12-312005-03-21Canada
All Natural Source Juicy Orange Vitamin CTablet500 mgOralWn Pharmaceuticals Ltd.1998-06-292009-09-28Canada
Ascorbate C-500Capsule500 mgOralSeroyal International Inc.1998-12-312001-08-09Canada
Ascorbic 500 Tab 500mgTablet500 mgOralPharmadex Laboratories Inc.1993-12-311999-08-28Canada
Ascorbic Acid 500mgTablet500 mgOralGreat Earth Companies, Inc.1998-08-252002-10-02Canada
Ascorbic Acid Cap 500mgCapsule500 mgOralThorne Research Inc.1984-12-312000-09-18Canada
Ascorbic Acid PowderPowder5 gOralAlbi Naturals1981-12-312008-07-17Canada
Ascorbic Acid Tab 1000mgTablet1 gOralBionatal Drug Co1977-12-311999-07-14Canada
Ascorbic Acid Tab 100mgTablet100 mgOralBionatal Drug Co1977-12-311999-07-14Canada
Ascorbic Acid Tab 250mgTablet250 mgOralBionatal Drug Co1977-12-311999-07-14Canada
Ascorbic Acid Tab 500mgTablet500 mgOralBionatal Drug Co1977-12-311999-07-14Canada
Ascorbic Acid Tab 500mgTablet500 mgOralEverest Pharmaceuticals Ltd.1982-12-311999-07-14Canada
Ascorbic Acid Tab 500mg USP W Non-med CherryTablet500 mgOralJamieson Laboratories Ltd1992-12-312002-06-25Canada
BABOR Baborganic Biological Enzyme CleanserPowder.375 g/75gTopicalBabor Cosmetics America, Corp.2008-11-012017-07-22Us
Bev C 1725 Tab 1000mgTablet1 gOralBeverly International Nutrition1986-12-311998-08-01Canada
Bio C 300 TabTablet300 mgOralLe Naturiste J.M.B. Inc.1980-12-312008-07-31Canada
Bio C 600 TabTablet600 mgOralHilcoa, Division Of Jeunique International1982-12-312006-12-11Canada
Bio Efferlife Vitamin C 1000mgTablet, effervescent1000 mgOralNaturale Science Inc.2003-06-212006-10-10Canada
Bio Flavono C Tab 100mgTablet100 mgOralLe Naturiste J.M.B. Inc.1980-12-312008-07-31Canada
Bio-cee Dietary SupplementTablet200 mgOralGarden State Nutritionals1998-08-312000-06-07Canada
Buffered Vitamin C 1000mgTablet1000 mgOralGeneral Nutrition Canada Inc.1997-11-262005-08-05Canada
C 1000Tablet1 gOralSeroyal International Inc.1988-12-312009-07-06Canada
C 3000Powder272 mgOralSeroyal International Inc.1980-12-312009-07-06Canada
C 350Tablet350 mgOralHilcoa, Division Of Jeunique International1973-12-311996-10-22Canada
C 500 Complete Tab 500mgTablet500 mgOralFlora Manufacturing And Distributing Ltd.1983-12-311999-10-18Canada
C 500 Mg ChewableTablet500 mgOralGahler Enterprises Ltd.1988-12-312009-09-28Canada
C 500mg Ascorbic AcidTablet500 mgOralWn Pharmaceuticals Ltd.1998-09-142003-08-01Canada
C ForteCapsule500 mgOralFrega Inc.1980-12-312008-02-13Canada
C Rola Tab 100mgTablet100 mgOralPharmetics (2011) Inc.1981-12-312009-07-30Canada
C Vite 100 Tab 100mgTablet100 mgOralPharmetics (2011) Inc.1981-12-312000-08-21Canada
C Vite 150 Tab 150mgTablet150 mgOralPharmetics (2011) Inc.1981-12-312006-07-27Canada
C Wafer 500 Chewable 500mgWafer500 mgOralNu Life Nutrition Ltd.1986-12-312000-05-23Canada
C-1000 Tab 1000mgTablet1 gOralSutra Health Systems Canada1986-12-311996-12-12Canada
C-1000 Tr Srt 1000mgTablet, extended release1 gOralNutri West Products Ltd.1988-12-312002-06-14Canada
C-500 CapletTablet500 mgOralHealth Wise Nutrition Inc.1994-12-312002-07-18Canada
C-500 Liq 50mg/mlLiquid50 mgOralBioforce Canada Inc.1994-12-311997-04-04Canada
C-curity-vitamin C CapCapsule375 mgOralEnrich International1994-12-312001-09-28Canada
C-rolla-250 Tab 250mg ChewableTablet250 mgOralNu Life Nutrition Ltd.1987-12-312000-05-23Canada
C1000 W Flavanoids TabTablet333 mgOralNutri Dyn Products Ltd.1976-12-311996-09-09Canada
C500 TabTablet500 mgOralNutri Dyn Products Ltd.1976-12-311996-09-09Canada
Calcium Ascorbate 1000mgCapsule1000 mgOralNatural Factors Nutritional Products Ltd.1996-12-312007-08-07Canada
Calcium Ascorbate Crystals 1250mg/0.25tspPowder1.25 gOralSwiss Herbal Remedies Ltd.1987-12-312009-08-04Canada
Calcium Ascorbate Crystals Vitamin C 1gm/mlPowder1 gOralVita Health Products Inc1991-12-312004-07-26Canada
Calcium Ascorbate FccPowder4.5 gOralAlbi Naturals1981-12-312009-07-15Canada
Calcium Ascorbate PwrPowder825 mgOralJamieson Laboratories Ltd1979-12-312000-09-08Canada
Calcium Ascorbate Pwr 1.3gm/1.25mlPowder1.3 gOralGahler Enterprises Ltd.1982-12-312007-08-07Canada
Calcium Ascorbate Tab 500mgTablet500 mgOralAlbi Imports Ltd.1986-12-312001-07-27Canada
Ce Vi Sol DpsSolution / drops50 mgOralMead Johnson Nutritionals1977-12-311996-09-30Canada
Chewable Acerola C 500mgTablet500 mgOralGreat Earth Companies, Inc.1998-08-252002-10-02Canada
Chewable C Tab 100mgTablet100 mgOralGahler Enterprises Ltd.1988-12-312001-07-26Canada
Chewable Vitamin C 100mgTablet100 mgOralVitality Products Inc.1979-12-311999-04-23Canada
Chewable Vitamin C 250mg With Orange JuiceTablet250 mgOralVita Health Products Inc1997-09-082005-07-20Canada
Chewable Vitamin C Tab 250mgTablet250 mgOralSutra Health Systems Canada1986-12-311996-12-12Canada
Chewable Vitamin C Tab. 500 Mg Grape FlavourTablet500 mgOralVita Health Products Inc1995-12-312004-07-26Canada
Chewable Vitamin C Wafers 500mgWafer500 mgOralPharmavite1987-12-312001-09-13Canada
Chewable Wafers Vitamin C 500 Mg - TabletTablet500 mgOralVita Health Products Inc1996-10-112002-07-31Canada
Comprime De Vitamine C 250mgTablet250 mgOralVitalab1990-12-312004-07-13Canada
Cran CCapsule100 mgOralHolista Health (Canada) Inc.1996-11-012006-08-02Canada
Daily Support CCapsule120 mgOralChanges International2000-10-012001-07-01Canada
Duo Cvp Cap 200mgCapsule200 mgOralAventis Pharma Ltd.1992-12-312002-07-29Canada
Effervescent Vit C 1000mgTablet, effervescent1 gOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1990-12-312000-07-27Canada
Ester - CTablet1000 mgOralNutraceutical Corporation2003-09-022007-08-02Canada
Ester CCapsule500 mgOralHolista Health (Canada) Inc.1996-11-132008-07-17Canada
Ester C 1000 mgTablet1000 mgOralHolista Health (Canada) Inc.2004-02-252007-08-03Canada
Ester C 1000mgTablet1000 mgOralWn Pharmaceuticals Ltd.2003-10-222008-07-17Canada
Ester-CTablet500 mgOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1998-08-102002-07-31Canada
Ester-CTablet500 mgOralVita Health Products Inc1998-05-202004-07-26Canada
Ester-C (1000 Mg)Tablet1000 mgOralNatural Factors Nutritional Products Ltd.2002-04-242008-07-17Canada
Ester-C 500Tablet500 mgOralPharmetics (2011) Inc.2002-09-302009-07-30Canada
Ester-C 500mgCapsule500 mgOralRegime Industries Ltd.2002-08-282008-07-10Canada
Ester-C With Non-medicinal Bioflavonoids, Quercetin, and Grape Seed ExtractTablet500 mgOralVita Health Products Inc2000-01-012004-07-26Canada
Exitox Tab 200mgTablet200 mgOralNutri Dyn Products Ltd.1982-12-311997-08-22Canada
Extra C 1000Tablet1000 mgOralLe Naturiste J.M.B. Inc.2001-02-022008-07-31Canada
Extra C 500Tablet500 mgOralLe Naturiste J.M.B. Inc.1999-07-072008-07-31Canada
Formula # 2 Pwr 15mg/gPowder15 mgOralGolden Pride/Rawleigh2001-06-212009-08-15Canada
Formula C-500 CapletTablet500 mgOralHealth Wise Nutrition Inc.1994-12-311998-08-25Canada
Formula Tc Vitamin C Tab 200mg USPTablet200 mgOralMetagenics, Inc.1997-01-272007-09-07Canada
Formula Vitamin C Tab 15mgTablet15 mgOralNatures Sunshine Products, Inc.1995-12-311996-09-23Canada
Fruity Bita C Tablets 125mgTablet125 mgOralRoyal Bodycare Canada Inc.1992-12-312002-07-26Canada
Gnc Timed Release Vitamin C 1500mg TabletsTablet, extended release1.5 gOralGeneral Nutrition Canada Inc.2000-08-012005-08-05Canada
Gnc Timed Release Vitamin C Tablets 500mgTablet, extended release500 mgOralGeneral Nutrition Canada Inc.2000-08-012006-08-03Canada
Good Health FormulaCapsule250 mgOralPharmavite1997-09-052000-08-24Canada
Hi-potent-C - CapCapsule500 mgOralHolista Health (Canada) Inc.1996-12-312001-08-01Canada
Hy C 3000 AnatabsTablet750 mgOralAnabolic Laboratories Inc.1970-12-311996-10-02Canada
Kamu Jay Liq 300mg/tspLiquid60 mgOralJamieson Laboratories Ltd1979-12-311997-08-13Canada
Kamu Jay Tab 150mgTablet150 mgOralJamieson Laboratories Ltd1977-12-312000-09-08Canada
Kanga CTablet, effervescent1000 mgOralLacombe Drugs (1992) LtdNot applicableNot applicableCanada
Kanga-kid Vitamin CTablet, effervescent500 mgOralLacombe Drugs (1992) LtdNot applicableNot applicableCanada
Life Vit C Timed Release Tab 1000mgTablet, extended release1 gOralShoppers Drug Mart Inc.1983-12-311997-08-15Canada
Life Vit C Timed Release Tab 500mgTablet, extended release500 mgOralShoppers Drug Mart Inc.1984-12-311997-08-15Canada
Liqud Vitamin CLiquid250 mgOralWn Pharmaceuticals Ltd.1999-11-122002-08-07Canada
Liquid Vitamin CLiquid250 mgOralNatural Factors Nutritional Products Ltd.1999-10-262007-08-07Canada
Liquid Vitamin C 500mgLiquid100 mgOralGeneral Nutrition Canada Inc.2003-09-202007-08-01Canada
Mega C 1000 Complex Tab 1000mgTablet1 gOralAlbi Naturals1988-12-312008-07-17Canada
Mega C 500 ComplexTablet500 mgOralAlbi Naturals1991-12-312009-07-15Canada
Mega C 500 Complex Tab 500mgTablet500 mgOralCountry Health Laboratories Ltd.1994-12-312001-07-27Canada
Mega C500 Complex Tab 500mgTablet500 mgOralCountry Health Laboratories Ltd.1994-12-312001-07-27Canada
Mr. Tumee WormsTablet, chewable30 mgOralVitamec Usa2003-04-152006-09-29Canada
Natural Fruit Chew C 250mg Tangy Orange FlavourTablet250 mgOralNatural Factors Nutritional Products Ltd.2001-01-012009-09-28Canada
Natural Source C 250 Tab 250mg ChewableTablet250 mgOralFlora Manufacturing And Distributing Ltd.1983-12-311997-09-24Canada
Neutral C With Echinacea & Lemon Bioflavonoids - CapCapsule660 mgOralNew Vision Nutritionals Company1998-06-072002-11-20Canada
NowCapsule25 mgOralChanges InternationalNot applicableNot applicableCanada
Now Ester-C 1000Tablet1000 mgOralNow Foods2005-04-212007-07-30Canada
Now Ester-C CapsCapsule500 mgOralNow Foods2005-04-212007-07-30Canada
Now Ester-C ComplexTablet500 mgOralNow Foods2005-04-212007-03-28Canada
Now Ester-C PowderPowder1000 mgOralNow Foods2005-05-162007-07-30Canada
Nutrol C Cap 150mgCapsule150 mgOralRolmex International Inc.1975-12-312008-07-09Canada
Nutrol C Tab 150mgTablet150 mgOralRolmex International Inc.1981-12-311997-08-08Canada
Orange C Tablets 150mgTablet150 mgOralGolden Neo Life Diamite International, Limited1993-12-311998-07-28Canada
Orange ChewableTablet500 mgOralDouglas Laboratories1995-12-312009-04-29Canada
Orti CCapsule500 mgOralSeroyal International Inc.1983-12-312009-07-06Canada
Phytomin C Tab 500mgTablet500 mgOralPhyto Health Corporation1979-12-311996-09-17Canada
Phytomin-C 500 Tab 500mgTablet500 mgOralHorizon SantÉ International Inc.1979-12-312003-11-27Canada
Rocky Mountain Oj's Chewable Vitamin C TabTablet500 mgOralAlbi Naturals1992-12-312008-07-17Canada
Sago-C-500 Tab 500mgTablet500 mgOralNutri West Products Ltd.1993-12-312002-06-14Canada
ScorbatatePowder1 gOralSeroyal International Inc.1988-12-312009-07-06Canada
Sodium Ascor Crystal 888.8mg/gm USPPowder888.8 mgOralVita Health Products Inc1996-10-112002-07-31Canada
Softgel Vit.c 200mg From Ester-C Br.ca Asc.Capsule200 mgOralNatrol, Inc.1997-09-011999-08-10Canada
Super B.P. Vitamin CCapsule250 mgOralNutraceutical Corporation2003-09-022007-08-02Canada
Super C 1000mgTablet1000 mgOralWn Pharmaceuticals Ltd.1998-09-142008-07-17Canada
Super C 500mg TabTablet500 mgOralSwiss Herbal Remedies Ltd.1986-12-311999-04-05Canada
Super C With Non-medicinal Rosehips TabTablet500 mgOralJamieson Laboratories Ltd1994-12-312001-09-14Canada
Super Citro Cee Srt 500mgTablet, extended release500 mgOralAnabolic Laboratories Inc.1981-12-311996-10-02Canada
Supplement De Vitamine CKit30 mgOralYves Rocher Inc.1999-10-182000-10-02Canada
Sustained Release Vitamin C 500mgTablet, extended release500 mgOralDiet Center Worldwide Inc.1989-12-312008-07-22Canada
Sveets Orange BurstLozenge100 mgOralSensible Delights Specialty Foods1998-09-162000-09-19Canada
Swiss Camu C Tab 150mgTablet150 mgOralSwiss Herbal Remedies Ltd.1976-12-311998-07-15Canada
Synergisti-CCapsule650 mgOralThorne Research Inc.1997-09-092005-08-26Canada
Tgi Tab 50mgTablet50 mgOralSeroyal International Inc.1980-12-311996-09-10Canada
Tianshi Beneficial CapsulesCapsule8 mgOralTianjin Tianshi Group Co., Ltd.Not applicableNot applicableCanada
Time Rel Vit C Tab 1000mgTablet, extended release1 gOralLee Adams Laboratories1981-12-312009-12-02Canada
Time Release C 500mgTablet, extended release500 mgOralHealth Wise Nutrition Inc.1996-10-222002-07-18Canada
Timed C 1000 + Caplet 1000mgTablet1 gOralNu Life Nutrition Ltd.1997-08-152005-03-15Canada
Timed Release C 1000mg SrtTablet, extended release1 gOralJamieson Laboratories Ltd1994-12-312002-06-25Canada
Timed Release C 1000mg TabTablet, extended release1 gOralNutricorp International1993-12-312002-09-06Canada
Timed Release Vit. C-1000 CapletTablet, extended release1 gOralHealth Wise Nutrition Inc.1994-12-312002-07-18Canada
Timed Release Vitamin C 500 mgTablet, extended release500 mgOralAccurex Health Care Manufacturing Inc.1999-01-192009-07-31Canada
Timedose Vitamin C 1000mgTablet, extended release1 gOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1981-12-312004-07-26Canada
Timedose Vitamin C Tab 500mgTablet, extended release500 mgOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1980-12-312004-07-26Canada
Tropicana Vitamin C SupplementSolution0.3 mgOralTropicana Canada2002-01-152007-06-21Canada
Vit C Chew Tab 300mgTablet300 mgOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Vit C Ctr 1000mgTablet, extended release1 gOralBioenergy Inc.1979-12-311998-06-03Canada
Vit C Ctr 500mgTablet, extended release500 mgOralBioenergy Inc.1979-12-311998-06-03Canada
Vit C Sustained Release Tab 1000mgTablet, extended release1 gOralPure Life International Prods Inc.1992-12-312000-07-27Canada
Vit C Tab 1000mgTablet1 gOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Vit C Tab 250mgTablet250 mgOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Vit C Tab 250mgTablet250 mgOralLaboratoire Lalco Inc.1976-12-311997-07-31Canada
Vit C Timed Release Tab 500mgTablet, extended release500 mgOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Vit.c With N-M.bioflav.rose Hips and RutinTablet500 mgOralVita Health Products Inc1996-10-112005-07-20Canada
Vita C 550 Ampoules Buvables 550mg/ampLiquid550 mgOralLe Naturiste J.M.B. Inc.1995-12-312002-06-19Canada
Vita C Tab 150mgTablet150 mgOralNutrimetics International (Canada) Inc.1985-12-311999-07-26Canada
Vita-worth Vitamin C Tablets 500mgTablet500 mgOralGeneral Nutrition Canada Inc.1997-11-272005-08-05Canada
Vitamin CCapsule500 mgOralNutraceutical CorporationNot applicableNot applicableCanada
Vitamin C 1000Capsule1000 mgOralFlora Manufacturing And Distributing Ltd.2001-04-102009-08-05Canada
Vitamin C 1000Tablet1 gOralOrganika Health Products Inc.1997-09-032004-06-28Canada
Vitamin C 1000 mgTablet1000 mgOralGfr Pharma Ltd.2002-10-202008-07-17Canada
Vitamin C 1000 Mg - TabletTablet1 gOralHealth Wise Nutrition Inc.1997-08-151998-08-25Canada
Vitamin C 1000 Mg Chewable - TabletTablet1 gOralPharmavite1995-12-312000-08-24Canada
Vitamin C 1000 Mg Timed Release - TabletTablet, extended release1 gOralPharmavite1995-09-012005-07-15Canada
Vitamin C 1000mgTablet1000 mgOralGreat Earth Companies, Inc.1998-08-252002-10-02Canada
Vitamin C 1000mg CapCapsule1 gOralThorne Research Inc.1997-04-182005-06-21Canada
Vitamin C 1000mg CapCapsule1 gOralFinlandia Consultants1990-12-311997-12-02Canada
Vitamin C 1000mg Dietary SupplementTablet1000 mgOralGarden State Nutritionals1998-09-222000-06-07Canada
Vitamin C 1000mg From Ester-C Brand Ca Asc.Tablet1 gOralNatrol, Inc.1997-09-012007-10-01Canada
Vitamin C 1000mg Time ReleaseTablet, extended release1000 mgOralWn Pharmaceuticals Ltd.1999-11-232009-09-28Canada
Vitamin C 1000mg Time Release FormTablet, extended release1 gOralVitality Products Inc.1979-12-311999-04-23Canada
Vitamin C 1000mg Timed Release TabletsTablet, extended release1 gOralWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.1994-12-311997-08-11Canada
Vitamin C 1000mg W/ Non-medicinal EchinaceaTablet1 gOralJamieson Laboratories Ltd1993-12-311997-08-13Canada
Vitamin C 1000mg W/rose Hips Timed Release TabletTablet, extended release1000 mgOralPharmetics (2011) Inc.1999-08-262009-07-30Canada
Vitamin C 100mg CapsulesCapsule100 mgOralHolista Health (Canada) Inc.1996-12-312002-08-06Canada
Vitamin C 1500mg - TabTablet1.5 gOralQuest Vitamins A Div Of Purity Life Health Products1996-11-211999-08-08Canada
Vitamin C 1500mg Time Released SrtTablet, extended release1.5 gOralNatural Factors Nutritional Products Ltd.1998-03-092002-08-02Canada
Vitamin C 1500mg Timed Release TabletTablet, extended release1.5 gOralAlive Vitamins1987-12-312002-07-12Canada
Vitamin C 250 mgTablet250 mgOralWn Pharmaceuticals Ltd.2002-03-132007-08-07Canada
Vitamin C 250 Mg Chewable - TabletTablet250 mgOralPharmavite1995-12-312000-08-24Canada
Vitamin C 250mg With Non-medicinal Echinacea & Lemon BioflavonoidsCapsule250 mgOralGeneral Nutrition Canada Inc.1997-09-162005-08-05Canada
Vitamin C 250mg With Non-medicinal Rose HipsTablet250 mgOralVita Health Products Inc1995-12-312005-07-20Canada
Vitamin C 250mg With Non-medicinal Rose Hips Dietary SupplementTablet250 mgOralGarden State Nutritionals1998-08-312000-06-07Canada
Vitamin C 350 Tab 350mgTablet350 mgOralAvacare, Division Of Jeunique International Inc.1973-12-311997-11-10Canada
Vitamin C 400mg TabTablet400 mgOralSisu Inc.1990-12-311998-08-11Canada
Vitamin C 500 Mg TabTablet500 mgOralNatures Sunshine Products, Inc.1995-12-311999-08-27Canada
Vitamin C 500 Mg (mixed Citrus Flavour)Tablet500 mgOralWn Pharmaceuticals Ltd.1999-04-302009-09-28Canada
Vitamin C 500 Mg Chewable - TabletTablet500 mgOralPharmavite1995-12-312000-08-24Canada
Vitamin C 500 Mg With RosehipsTablet500 mgOralGfr Pharma Ltd.2002-10-102008-07-17Canada
Vitamin C 500mgTablet500 mgOralWn Pharmaceuticals Ltd.1999-11-232008-07-17Canada
Vitamin C 500mgTablet500 mgOralBioprint Laboratories Ltd2000-06-062002-08-01Canada
Vitamin C 500mgTablet500 mgOralWn Pharmaceuticals Ltd.1999-11-232009-09-28Canada
Vitamin C 500mg (chewable Orange)Tablet500 mgOralWn Pharmaceuticals Ltd.1999-04-302009-09-28Canada
Vitamin C 500mg Caps Time ReleaseCapsule, extended release500 mgOralLaboratoire Lalco Inc.1981-12-312007-08-16Canada
Vitamin C 500mg Src Time ReleaseCapsule, extended release500 mgOralSuperco Enr.1981-12-312008-11-19Canada
Vitamin C 500mg TabTablet500 mgOralNutricorp International1993-12-312009-08-05Canada
Vitamin C 500mg TabTablet500 mgOralJamieson Laboratories Ltd1994-12-312002-06-25Canada
Vitamin C 500mg TabletsTablet500 mgOralHolista Health (Canada) Inc.1997-07-022005-08-04Canada
Vitamin C 500mg Time ReleaseTablet, extended release500 mgOralWn Pharmaceuticals Ltd.1999-11-232005-08-15Canada
Vitamin C 500mg Timed ReleaseTablet, extended release500 mgOralPharmavite1995-12-312005-07-15Canada
Vitamin C 500mg Timed Release Tab USPTablet, extended release500 mgOralJamieson Laboratories Ltd1980-12-312009-07-29Canada
Vitamin C 500mg Timed Release TabletsTablet, extended release500 mgOralWampole Brands1994-12-312004-06-29Canada
Vitamin C 500mg With Non-medicinal EchinaceaTablet500 mgOralHolista Health (Canada) Inc.1997-08-132002-08-06Canada
Vitamin C 500mg With Non-medicinal Rose HipsTablet500 mgOralGarden State Nutritionals1998-09-222000-06-07Canada
Vitamin C 600mgTablet600 mgOralGeneral Nutrition Canada Inc.2001-10-202005-08-05Canada
Vitamin C 60mgTablet60 mgOralWn Pharmaceuticals Ltd.1999-04-092008-07-17Canada
Vitamin C Ascorbic Acid Tab 1000mgTablet1 gOralShoppers Drug Mart Inc.1979-12-311999-08-11Canada
Vitamin C Cap 1000mgCapsule1 gOralRheingold Food International Ltd.1987-12-312007-07-26Canada
Vitamin C Chewable 250mgTablet250 mgOralGfr Pharma Ltd.2002-10-202004-06-15Canada
Vitamin C Chewable 500mgTablet500 mgOralGfr Pharma Ltd.2002-10-202004-06-11Canada
Vitamin C CrystalsPowder1.3 gOralGahler Enterprises Ltd.1979-12-312007-08-07Canada
Vitamin C CrystalsPowder2 gOralQuest Vitamins A Div Of Purity Life Health Products1979-12-311998-07-15Canada
Vitamin C CrystalsPowder3 gOralAnabolic Laboratories Inc.1981-12-311996-10-02Canada
Vitamin C CrystalsPowder1200 mgOralWn Pharmaceuticals Ltd.2002-04-152006-08-08Canada
Vitamin C CrystalsPowder100 %OralVita Health Products Inc1982-12-312004-07-26Canada
Vitamin C CrystalsGranule1000 mgOralOrganika Health Products Inc.1997-05-102009-08-05Canada
Vitamin C Crystals 5gm/5mlPowder5 gOralNutristar Health Products (1987) Inc.1983-12-311996-09-09Canada
Vitamin C Crystals Pwr 4000mg/tspPowder4 gOralNu Life Nutrition Ltd.1991-12-312005-03-15Canada
Vitamin C Extra Time Released Tab 1800mgTablet, extended release1.8 gOralGahler Enterprises Ltd.1980-12-312000-08-01Canada
Vitamin C Orange Chewable Tab 500mg USPTablet500 mgOralVitalab1990-12-312005-07-12Canada
Vitamin C Src 500mg Timed ReleaseCapsule, extended release500 mgOralSwiss Herbal Remedies Ltd.1979-12-312003-09-10Canada
Vitamin C Srt 1.5gmTablet, extended release1.5 gOralAnabolic Laboratories Inc.1981-12-311996-10-02Canada
Vitamin C Srt 1000mgTablet, extended release1 gOralAnabolic Laboratories Inc.1981-12-311996-10-02Canada
Vitamin C Srt 1500mgTablet, extended release1.5 gOralJamieson Laboratories Ltd1978-12-312004-07-01Canada
Vitamin C Srt 500mgTablet, extended release500 mgOralBioforce Canada Inc.1985-12-311997-04-04Canada
Vitamin C Sustained Release Tabs 1000mgTablet, extended release1 gOralBioforce Canada Inc.1993-12-311997-07-22Canada
Vitamin C Tab 1000mgTablet1 gOralWampole Brands1973-12-312009-06-19Canada
Vitamin C Tab 1000mgTablet1 gOralWeider Health Products1985-12-311999-09-09Canada
Vitamin C Tab 1000mgTablet1 gOralCreative Nutrition Canada Corp.1984-12-312009-07-10Canada
Vitamin C Tab 1000mgTablet1 gOralVita Health Products Inc1979-12-312004-07-26Canada
Vitamin C Tab 1000mgTablet1 gOralIcn Pharmaceuticals1976-12-312005-04-26Canada
Vitamin C Tab 1000mg Timed ReleaseTablet, extended release1 gOralVita Health Products Inc1996-10-112008-08-05Canada
Vitamin C Tab 1000mg USPTablet1 gOralPharmavite1987-12-312006-07-05Canada
Vitamin C Tab 100mgTablet100 mgOralLes Produits Gerbex Inc.1970-12-311997-08-11Canada
Vitamin C Tab 100mgTablet100 mgOralVita Health Products Inc1985-12-312002-07-31Canada
Vitamin C Tab 100mgTablet100 mgOralWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.1973-12-311996-09-09Canada
Vitamin C Tab 100mgTablet100 mgOralCountry Health Laboratories Ltd.1982-12-312001-07-27Canada
Vitamin C Tab 100mgTablet100 mgOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1972-12-312002-07-31Canada
Vitamin C Tab 100mgTablet100 mgOralShoppers Drug Mart Inc.1977-12-311997-08-15Canada
Vitamin C Tab 1500mg Timed ReleaseTablet, extended release1.5 gOralSwiss Herbal Remedies Ltd.1979-12-312007-07-31Canada
Vitamin C Tab 250mgTablet250 mgOralCountry Health Laboratories Ltd.1982-12-312001-07-27Canada
Vitamin C Tab 250mgTablet250 mgOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1972-12-312002-07-31Canada
Vitamin C Tab 250mgTablet250 mgOralShoppers Drug Mart Inc.1977-12-311998-08-14Canada
Vitamin C Tab 250mgTablet250 mgOralRandle Pharmaceutical Inc.1987-12-311997-05-30Canada
Vitamin C Tab 250mgTablet250 mgOralWampole Brands1973-12-312004-06-29Canada
Vitamin C Tab 250mgTablet250 mgOralAlbi Imports Ltd.1980-12-311996-09-09Canada
Vitamin C Tab 250mg USPTablet250 mgOralPharmavite1987-12-312000-08-24Canada
Vitamin C Tab 250mg WatkinsTablet250 mgOralWatkins Incorporated1975-12-312000-01-15Canada
Vitamin C Tab 500 mgTablet500 mgOralPurity Life Health Products A Division Of Sunopta Inc.2002-06-012007-07-26Canada
Vitamin C Tab 500mgTablet500 mgOralNutristar Health Products (1987) Inc.1979-12-311996-09-09Canada
Vitamin C Tab 500mgTablet500 mgOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1972-12-312002-07-31Canada
Vitamin C Tab 500mgTablet500 mgOralSwiss Herbal Remedies Ltd.1984-12-312001-08-02Canada
Vitamin C Tab 500mgTablet500 mgOralNutristar Health Products (1987) Inc.1979-12-311996-09-09Canada
Vitamin C Tab 500mgTablet500 mgOralLaboratoire Lalco Inc.1974-12-312008-07-29Canada
Vitamin C Tab 500mgTablet500 mgOralCountry Health Laboratories Ltd.1982-12-312001-07-27Canada
Vitamin C Tab 500mgTablet500 mgOralShoppers Drug Mart Inc.1977-12-311997-08-15Canada
Vitamin C Tab 500mgTablet500 mgOralAlbi Imports Ltd.1979-12-311996-09-09Canada
Vitamin C Tab 500mgTablet500 mgOralAlive Vitamins1984-12-312004-07-08Canada
Vitamin C Tab 500mgTablet500 mgOralVitality Products Inc.1979-12-311999-04-23Canada
Vitamin C Tab 500mgTablet500 mgOralRandle Pharmaceutical Inc.1987-12-311997-05-30Canada
Vitamin C Tab 500mgTablet500 mgOralRheingold Food International Ltd.1985-12-311996-09-16Canada
Vitamin C Tab 500mgTablet500 mgOralLab Bio Chimique Inc.,Division Of Technilab Pharma Inc.1973-12-311999-01-22Canada
Vitamin C Tab 500mgTablet500 mgOralJamieson Laboratories Ltd1979-12-312009-07-29Canada
Vitamin C Tab 500mg USPTablet500 mgOralPharmavite1995-12-312002-07-25Canada
Vitamin C Tab 500mg USPTablet500 mgOralPharmavite1987-12-312006-07-05Canada
Vitamin C Tablets 1000mgTablet1000 mgOralD.C. Labs Limited1982-12-312005-07-19Canada
Vitamin C Tablets 1500mg Timed ReleaseTablet, extended release1.5 gOralVita Health Products Inc1995-12-312004-07-26Canada
Vitamin C Tablets 250mgTablet250 mgOralD.C. Labs Limited1973-12-312003-07-11Canada
Vitamin C Tablets 500mgTablet500 mgOralD.C. Labs Limited1973-12-312005-07-19Canada
Vitamin C Tablets 500mgTablet500 mgOralTechnilab Pharma Inc.1997-08-192005-08-05Canada
Vitamin C Tablets 500mgTablet500 mgOralInternational Nutrition Ltd.1996-07-262001-08-17Canada
Vitamin C Tablets Sustained Release 500mgTablet, extended release500 mgOralD.C. Labs Limited1987-12-312003-07-11Canada
Vitamin C Tablets Time Release 1000mgTablet, extended release1 gOralInternational Nutrition Ltd.1996-07-262001-08-17Canada
Vitamin C Tablets Time Release 500mgTablet, extended release500 mgOralInternational Nutrition Ltd.1996-07-262001-08-17Canada
Vitamin C Tablets USP 500mgTablet500 mgOralNpr Laboratories Inc.Not applicableNot applicableCanada
Vitamin C Timed Release Tab 1000mgTablet, extended release1 gOralNobel Pharm Enr.1995-12-312001-10-15Canada
Vitamin C Timed Release Tab 1000mgTablet, extended release1 gOralLaboratoire Lalco Inc.1989-12-312007-08-16Canada
Vitamin C Timed Release Tab 1500mgTablet, extended release1.5 gOralVita Health Products Inc1986-12-312005-07-20Canada
Vitamin C Timed Release Tab 1500mgTablet, extended release1.5 gOralAlbi Naturals1985-12-312008-07-17Canada
Vitamin C Timed Release Tab 500mgTablet, extended release500 mgOralAlbi Imports Ltd.1985-12-312006-08-04Canada
Vitamin C Ultra Fine Pwr 1000mg/tspPowder1 gOralKlaire Labs Inc.1983-12-311999-01-18Canada
Vitamin C-force 1000mg TabletsTablet1000 mgOralPrairie Naturals2001-12-292005-09-25Canada
Vitamin C-force 500mg TabletsTablet500 mgOralPrairie Naturals2001-12-292005-09-25Canada
Vitamine C 250 Mg Masticable - TabletTablet250 mgOralNobel Pharm Enr.1995-12-312001-10-15Canada
Vitamine C 250 Mg USP - TabletTablet250 mgOralNobel Pharm Enr.1995-12-312000-08-01Canada
Vitamine C 500 Mg Raisin - TabletTablet500 mgOralNobel Pharm Enr.1995-12-312001-10-15Canada
Vitamine C 500 Mg USP - TabletTablet500 mgOralNobel Pharm Enr.1995-12-312001-10-15Canada
Vitamine C - Liq Orl 50mg/mlLiquid50 mgOralLand Art Inc.1996-10-292008-06-26Canada
Vitamine C 1000 Action ProlongeeTablet, extended release1000 mgOralGamme Nature1989-12-312008-07-31Canada
Vitamine C 1000 Tab 1000mgTablet1 gOralLe Naturiste J.M.B. Inc.1990-12-312001-08-01Canada
Vitamine C 1000mg-liqLiquid1 gOralLe Naturiste J.M.B. Inc.1995-12-312008-07-31Canada
Vitamine C 150 mgCapsule150 mgOralLes Produits Gerbex Inc.1971-12-312008-08-14Canada
Vitamine C 500Tablet500 mgOralLaboratoire Lalco Inc.1998-06-052008-07-29Canada
Vitamine C 500 Action ProlongeeTablet, extended release500 mgOralGamme Nature1990-12-312004-07-26Canada
Vitamine C Cap 500mgCapsule500 mgOralAlsi Cie Ltee1988-12-312003-05-21Canada
Vitamine C Cap 500mgCapsule500 mgOralPharmalab Inc.1995-12-311997-08-08Canada
Vitamine C Liq 500mg/10mlLiquid500 mgOralSantÉ Naturelle (Ag) LtÉe1993-12-312007-08-03Canada
Vitamine C Tab 100mgTablet100 mgOralCarmaran LtÉe1979-12-311996-09-09Canada
Vitamine C Tab 100mg MasticablesTablet100 mgOralLaboratoire Lalco Inc.1980-12-311997-07-31Canada
Vitamine C Tab 100mg USPTablet100 mgOralNobel Pharm Enr.1988-12-311997-07-31Canada
Vitamine C Tab 500mgTablet500 mgOralQuest Vitamins A Div Of Purity Life Health Products1980-12-311997-08-08Canada
Vitamine C Timed Release Tab 500mgTablet, extended release500 mgOralNobel Pharm Enr.1989-12-311998-08-14Canada
Vitamine C Timed Release Tab 500mgTablet, extended release500 mgOralLaboratoire Lalco Inc.1989-12-312007-08-16Canada
Vitarich CTablet500 mgOralWn Pharmaceuticals Ltd.2000-07-072002-08-02Canada
Unapproved/Other Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Ascorbic AcidInjection, solution500 mg/mLIntramuscular; Intravenous; SubcutaneousAmerican Regent1989-12-15Not applicableUs
Ascorbic AcidInjection, solution500 mg/mLIntramuscular; Intravenous; SubcutaneousFlon Laboratories Llc2017-04-01Not applicableUs
Ascorbic AcidInjection, solution500 mg/mLIntramuscular; Intravenous; SubcutaneousMylan Institutional1999-06-012017-04-14Us
Ascorbic AcidInjection, solution500 mg/mLIntramuscular; Intravenous; SubcutaneousRaw Materials International Overseas Llc2015-07-02Not applicableUs
Ascorbic AcidInjection, solution500 mg/mLIntramuscular; Intravenous; SubcutaneousMylan Institutional1999-06-01Not applicableUs
Ascorbic AcidInjection, solution500 mg/mLIntravenousRemedy Repack2015-10-092016-03-29Us
Ascorbic AcidInjection, solution500 mg/mLIntramuscular; Intravenous; SubcutaneousThe Torrance Company1999-06-01Not applicableUs
Dr Cellapy SR PremiumKitGm Holdings Co., Ltd2014-10-10Not applicableUs
Mega-C-acid PlusInjection, solution500 mg/mLIntramuscular; Intravenous; SubcutaneousMerit Pharmaceuticals2010-01-01Not applicableUs
International/Other Brands
Ascoltin / Ascorbicap
Brand mixtures
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
A & C PowderPowder, for solutionOralStandard Process Inc.Not applicableNot applicableCanada
Acetabolan III Vitamin and Mineral SupplementCapsuleOralIovate Health Sciences International Inc.2003-12-052007-07-18Canada
Acetabolan-II Vitamin and Mineral SupplementCapsuleOralIovate Health Sciences International Inc.2000-11-202005-06-21Canada
Acti-megascorb Crystals PwrPowderOralActi Form Ltd.1991-12-312005-03-21Canada
Acti-MN + B1 + C CapletTabletOralActi Form Ltd.1991-12-312005-03-21Canada
Active FETabletOralGm Pharmaceuticals2013-11-11Not applicableUs
Adc ComprimesTabletOralBio Vita1990-12-311996-09-09Canada
Adrenergy TabletsTabletOralMorter HealthsystemNot applicableNot applicableCanada
Adult Infuvite Multiple VitaminsInjection, solutionIntravenousSandoz2005-05-18Not applicableUs
Allbee With C 550 CapCapsuleOralWhitehall Robins Inc.1994-12-312003-08-01Canada
Allbee With Vitamin C CapCapsuleOralWhitehall Robins Inc.1994-12-312000-07-26Canada
Am CapsCapsuleOralNew Vision Nutritionals Company1998-10-012002-11-20Canada
AmdCapsuleOralSeroyal International Inc.1997-06-272009-07-06Canada
Animal Shaped Chew Vit C Tab 250mgTabletOralHall Laboratories, Ltd.1982-12-312003-09-11Canada
AntlervironCapsuleOralClassical Remedia LtdNot applicableNot applicableCanada
AppedrineTabletOralChattem, Inc.1975-12-312004-07-08Canada
ArmaxTabletOralEnzymatic Therapy, Inc.1997-03-202001-08-02Canada
Ascorbex 500 TabTabletOralSantÉ Naturelle (Ag) LtÉe1988-12-312004-08-05Canada
Ascorbic Acid Tab 100mg Orange FlavorTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1969-12-311997-10-14Canada
Ascorbic Acid Tab 250mg Orange FlavorTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1969-12-311997-10-14Canada
Astral C TabTabletOralAlbi Naturals1994-12-312008-07-17Canada
B & J Formula Dietary SupplementTabletOralGarden State NutritionalsNot applicableNot applicableCanada
B C Antistress CapCapsuleOralLes Laboratoires Bio SantÉ Inc.1992-12-311996-09-10Canada
B Complex 500 TabTabletOralNobel Pharm Enr.1981-12-311998-08-14Canada
B Complex Plus C 300mg TabTabletOralNutricorp International2000-08-012009-08-05Canada
B Complex W C and B12 InjLiquidIntramuscular; IntravenousE L Stickley And Co Ltd.1963-12-311996-09-09Canada
B Complex W C Forte CapCapsuleOralEverest Pharmaceuticals Ltd.1980-12-311999-07-14Canada
B Complex W Vit C W Non-med Yeast&liver TabTabletOralPharmavite1991-12-311997-09-04Canada
B Complex W Vitamin C Fortis CapCapsuleOralShoppers Drug Mart Inc.1984-12-311998-08-14Canada
B Complex With C 300mgCapsuleOralVita Health Products Inc1985-12-312008-08-05Canada
B Complex With C 300mg TabTabletOralPharmavite1987-12-312005-07-15Canada
B Complex With C 550mgCapsuleOralVita Health Products Inc1990-12-312002-07-31Canada
B Plus C 300mg Timed ReleaseTablet, extended releaseOralVita Health Products Inc1981-12-312008-08-05Canada
B Stress C + Iron & ViteTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1990-12-312004-07-26Canada
B Totum 500TabletOralDesbergers LtÉe, Division Of Technilab Inc.1966-12-311999-09-17Canada
B VirolElixirOralRolmex International Inc.1975-12-312008-07-09Canada
B With C 500 CapCapsuleOralPharmetics (2011) Inc.1995-12-312006-07-27Canada
B-2 100mg With C 20mgTabletOralGahler Enterprises Ltd.1986-12-312006-07-26Canada
B-complex With Vitamin C, Biotin, Folic AcidTabletOralWn Pharmaceuticals Ltd.2001-11-232009-09-28Canada
B-plexTabletOralWn Pharmaceuticals Ltd.1999-10-202000-01-28Canada
B-plus - TabTabletOralChampion's Choice Advanced Nutrition Inc.1997-06-111999-08-28Canada
BacminTablet, coatedOralMarnel Pharmaceuticals, Llc2000-04-01Not applicableUs
Balanced B-complex Vit + Vit C&e TabTabletOralPharmavite1991-12-312006-07-05Canada
Beminal W C Fortis InjPowder, for solutionIntramuscular; IntravenousAyerst Laboratories1951-12-311996-09-10Canada
Beminal With C Fortis CapCapsuleOralWyeth Ayerst Canada Inc.1994-12-312001-08-03Canada
Beminal With C Fortis PwsPowder, for solutionIntravenousWyeth Ayerst Canada Inc.1994-12-312000-08-02Canada
Beta-carotene 10,000 Iu With Vitamins C & ETabletOralJamieson Laboratories Ltd1993-12-312001-09-14Canada
Betafant TabTabletOralLes Laboratoires Vachon Inc.1994-12-311996-09-09Canada
BioFerr 90Tablet, film coatedOralBiocomp Pharma, Inc.2014-07-01Not applicableUs
Biovim TabTabletOralLe Naturiste J.M.B. Inc.1977-12-312008-07-31Canada
BiovitaGranuleOralIldong Pharmaceutical Co., Ltd.2015-06-03Not applicableUs
Bodysmarts With Vitamins A, C and ETabletOralCadbury Adams Canada Inc.2001-02-062005-07-28Canada
BseltzerGranule, effervescentOralAbundance Marketing Ltd.2001-11-112007-07-23Canada
Buffered Vitamin C Plus MagnesiumCapsuleOralTwin Laboratories Inc.1995-12-311999-11-10Canada
Buffered Vitamin C Powder With Ca Mg and KPowderOralThorne Research Inc.1997-04-182005-06-21Canada
Buffered Vitamin C Pwr W Cal-mag-potassiumPowderOralSisu Inc.1987-12-312009-08-04Canada
Bugs Bunny and Friends Multiple VitaminsTabletOralBayer Inc Consumer Care1996-12-312004-04-15Canada
Bugs Bunny Chew Multi Vit Plus IronTabletOralMiles Inc. Pharmaceutical Division1983-12-311996-09-09Canada
C 106 TabTabletOralNf Formulas Inc.1983-12-312001-09-18Canada
C-1000 Plus Zinc & PotassiumTabletOralNu Life Nutrition Ltd.1987-12-312005-03-15Canada
C-apnto-B6 Vitamins W Magnesium TabTabletOralMetagenics, Inc.1989-12-311996-10-02Canada
C-B ComplexTabletOralAvacare, Division Of Jeunique International Inc.1984-12-311996-09-09Canada
C-crystals With CalciumPowderOralAlive Vitamins1985-12-311997-08-11Canada
C-forceCapsuleOralPrairie Naturals1997-04-012002-06-21Canada
C-Nate DHACapsule, gelatin coatedOralCenturion Labs2013-01-01Not applicableUs
C-plus - TabTabletOralChampion's Choice Advanced Nutrition Inc.1997-06-111999-08-28Canada
C.A.G. TabTabletOralNutrition For Life International1996-11-272000-08-11Canada
C.H.V. FormulaCapsuleOralNihon Kenko Zoushin Kenkyukai Canada Inc., Subsidery Of Nikken Usa Inc.1999-09-252005-07-15Canada
Cal & Mag Hvp Chel Plus C Potass & Zinc TabTabletOralGahler Enterprises Ltd.1989-12-312000-09-05Canada
Cal Mag Drink With Vitamin CPowderOralWampole Brands2003-01-012004-06-29Canada
Cal-mag Complete With Zinc, C and DTabletOralQuest Vitamins A Div Of Purity Life Health Products1992-12-312009-07-14Canada
Cal-mag Vitamin C and Zinc TabTabletOralSwiss Herbal Remedies Ltd.1991-12-312004-09-03Canada
Calcium Ascorbate 1000 Mg - TabletTabletOralHealth Wise Nutrition Inc.1997-08-152000-07-29Canada
Calcium Ascorbate Cap 850mgCapsuleOralQuest Vitamins A Div Of Purity Life Health Products1984-12-312001-07-06Canada
Calcium Ascorbate Ctr Srt 450mgTabletOralBioenergy Inc.1979-12-311998-06-03Canada
Calcium Ascorbate PowderPowderOralEster C Health Co, Division Of Inter Cal Corp1987-12-311998-09-02Canada
Calcium Ascorbate Tab 550mgTabletOralEster C Health Co, Division Of Inter Cal Corp1987-12-311998-09-02Canada
Calcium Complex High GradeCapsuleOralNew Spirit Naturals, Inc.Not applicableNot applicableCanada
Calcium Magnesium Avec Vitamine CTabletOralLes Aliments Nutri Source Inc.1989-12-312009-08-05Canada
Calcium With Mg Zn Mn Cu CR Si and Vit. C & DTabletOralJamieson Laboratories Ltd1993-12-312001-09-14Canada
Calcium With Vitamins C and D TabTabletOralPure Life International Prods Inc.1993-12-312000-07-27Canada
CalmaxPowderOralMedia Power, Inc.2001-08-202009-09-04Canada
CalplusTabletOralLifestyles Canada Corporation1998-08-072000-07-16Canada
Carbassist TabletsTabletOralWyeth Ltd.1978-12-312006-07-24Canada
CarbawayTabletOralAbundance Marketing Ltd.2000-04-122007-07-26Canada
Carti-aide TabTabletOralAvant Garde, Les SupplÉments1995-12-311998-07-08Canada
Cataplex A-C TabTabletOralStandard Process Inc.Not applicableNot applicableCanada
Cda-21 Vitamins With Non-medicinal Probiotic ComplexCapsuleOralRx Vitamins Inc.2006-08-012007-10-25Canada
Cedevita Plus Vitamin SupplementPowderOralPliva, Pharmaceutical, Chemical, Food And Cosmetic Industry, Inc.Not applicableNot applicableCanada
Cedevita Sugar-free Vitamin SupplementPowderOralPliva, Pharmaceutical, Chemical, Food And Cosmetic Industry, Inc.Not applicableNot applicableCanada
Cell-wiseTabletOralMelaleuca, Inc.1998-01-122004-07-30Canada
Cell-wise Natural SourceTabletOralMelaleuca, Inc.1998-05-262005-06-28Canada
Central-vite 18 EssentialTabletOralVita Health Products Inc1998-04-242002-07-31Canada
Century CompleteTabletOralVita Health Products Inc1998-03-172002-07-31Canada
Chela-manganese 50 PlusTabletOralNu Life Nutrition Ltd.1987-12-312000-03-03Canada
Chelated Cal-mag(2:1)with Zn Vit.c and DTabletOralHealth Wise Nutrition Inc.1995-12-312002-07-18Canada
Chelated Cal/mag/zn With VitaminsTabletOralHealth Wise Nutrition Inc.2000-04-072002-07-18Canada
Chew.multiple Vits.with Extra C for ChildrenTabletOralRandle Pharmaceutical Inc.1996-09-191999-09-03Canada
Chewable Multiple Vit Plus Iron for ChildrenTabletOralRandle Pharmaceutical Inc.1996-09-191999-09-03Canada
Chewable Multiple Vitamins for ChildrenTabletOralRandle Pharmaceutical Inc.1996-09-191999-09-03Canada
Chewable Multiple Vitamins Plus Extra CTabletOralRandle Pharmaceutical Inc.1993-12-311999-09-03Canada
Chewable Multiple Vitamins Plus Iron TabTabletOralRandle Pharmaceutical Inc.1993-12-311999-09-03Canada
Chewable Multiple Vitamins TabTabletOralRandle Pharmaceutical Inc.1993-12-311999-09-03Canada
Chewable MultivitaminsTabletOralWn Pharmaceuticals Ltd.2002-05-312008-07-17Canada
Chewable Multivitamins Plus IronTabletOralWn Pharmaceuticals Ltd.2002-05-312007-08-07Canada
Chewable Vit C 100mgTabletOralBioforce Canada Inc.1994-12-311997-04-04Canada
Chewable Vitamin C 100mg - TabTabletOralVita Health Products Inc1996-10-182002-07-31Canada
Chewable Vitamin C 250mgTabletOralVita Health Products Inc1996-10-182004-07-26Canada
Chewable Vitamin C 500mgTabletOralRandle Pharmaceutical Inc.1987-12-311997-05-30Canada
Chewable Vitamin C 500mg TabTabletOralHall Laboratories, Ltd.1987-12-312003-09-11Canada
Chewable Vitamin C Tab 1000mgTabletOralWampole Brands1982-12-312009-06-19Canada
Children Choice Multivit Chewable TabTabletOralSwiss Herbal Remedies Ltd.1990-12-312009-08-04Canada
Children Choice Multivitamin W Iron Chew TabTabletOralSwiss Herbal Remedies Ltd.1991-12-312009-08-04Canada
Children Pediatric Vitamins DropsSolution / dropsOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1990-12-312002-07-31Canada
Children Vitamin DropsLiquidOralWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.1998-08-122002-07-29Canada
Children's Chewable Multi Vit W IronTabletOralShoppers Drug Mart Inc.1982-12-311997-08-15Canada
Children's Chewable Multi VitaminsTabletOralShoppers Drug Mart Inc.1982-12-311997-08-15Canada
Children's Chewable Multi Vitamins With Iron TabletsTabletOralVita Health Products Inc1998-05-202008-08-05Canada
Children's Chewable Multi-vitaminTabletOralWn Pharmaceuticals Ltd.2000-03-012007-08-07Canada
Children's Chewable Multi-vitamin Complete With MineralsTabletOralWn Pharmaceuticals Ltd.2000-03-012001-07-18Canada
Children's Chewable Multiple Vit.plus IronTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1997-10-102002-07-31Canada
Children's Chewable Multiple Vitamins - TabTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1997-10-102002-07-31Canada
Children's Chewable Multiple Vitamins (chewable Tablets)TabletOralPharmetics (2011) Inc.1999-08-162009-07-30Canada
Children's Chewable Multiple Vitamins With Extra Vitamin C (chewable Tablets)TabletOralPharmetics (2011) Inc.1999-08-162009-07-30Canada
Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets)TabletOralPharmetics (2011) Inc.1999-08-162009-07-30Canada
Children's Vitamins ChewableTabletOralVita Health Products Inc1990-12-312002-07-31Canada
Children's Vitamins W Iron ChewableTabletOralVita Health Products Inc1990-12-312002-07-31Canada
Childrens Chew Multi Vitamin TabTabletOralNutristar Health Products (1987) Inc.1983-12-311996-09-09Canada
Childrens Chewable Multiple VitaminsTabletOralKsl Pharmaceuticals1994-12-311999-08-12Canada
Childrens Chewable Multiple Vitamins Plus FeTabletOralKsl Pharmaceuticals1994-12-312000-08-29Canada
Childrens Chewable Multiple Vitamins TabTabletOralPharmavite1987-12-312000-08-24Canada
Childrens Chewable MultivitaminsTabletOralRandle Pharmaceutical Inc.1987-12-311997-05-30Canada
Childrens Chewable Multivitamins W IronTabletOralRandle Pharmaceutical Inc.1987-12-311997-05-30Canada
Childrens Chewable Vitamin TabTabletOralPharmetics (2011) Inc.1993-12-312006-07-27Canada
Childrens Chewable VitaminsTabletOralD.C. Labs Limited1974-12-312003-07-11Canada
Childrens Multiple Vit and Min Chew TabTabletOralCountry Health Laboratories Ltd.1982-12-312008-07-17Canada
ChromagenCapsuleOralAvion Pharmaceuticals, Llc2017-01-23Not applicableUs
CitraNatal B-CalmKitMission Pharmacal2010-02-10Not applicableUs
CitraNatal BloomTablet, film coatedOralMission Pharmacal2017-08-01Not applicableUs
CitraNatal DHATabletOralMission Pharmacal2007-11-20Not applicableUs
CitraNatal RxTabletOralMission Pharmacal2014-08-11Not applicableUs
Citron Chaud Cumberland PwsPowder, for solutionOralProdemdis Enr.1992-12-312000-08-03Canada
Citron Chaud DM Cumberland PwsPowder, for solutionOralProdemdis Enr.1992-12-312000-08-03Canada
Citron Chaud DM Option + PwsPowder, for solutionOralProdemdis Enr.1993-12-312010-07-15Canada
Citron Chaud Extra FortPowderOralPharmalab Inc.Not applicableNot applicableCanada
Cmp PlexTabletOralNutraceutical Corporation2003-09-022006-08-02Canada
Cold & FluPowder, for solutionOralPharmascience Inc1993-12-30Not applicableCanada
Cold and SinusPowder, for solutionOralPharmetics (2011) Inc.Not applicableNot applicableCanada
Complete Multivitamins and Minerals for ChildrenTabletOralQuest Vitamins A Div Of Purity Life Health Products2001-01-312004-06-29Canada
Complete Multivitamins and Minerals Tablets Timed ReleaseTablet, extended releaseOralPharmetics (2011) Inc.1999-07-262009-07-30Canada
Concept DHACapsule, liquid filledOralUs Pharmaceutical Corporation2009-06-24Not applicableUs
Concept OBCapsuleOralUs Pharmaceutical Corporation2009-01-01Not applicableUs
Contac Extend-C Sustained Release CapsulesCapsule, extended releaseOralGlaxosmithkline IncNot applicableNot applicableCanada
Croq-vit Pour EnfantsTabletOralNutrivac Ltee1987-12-311996-09-09Canada
CyroplexTabletOralTherapeutic Foods Co.1987-12-312003-07-16Canada
Cyruta TabTabletOralTherapeutic Foods Co.1991-12-312004-07-22Canada
D Pantothenic 500mg With 100mg CTabletOralGahler Enterprises Ltd.1986-12-312000-08-01Canada
Derma-forceCapsuleOralPrairie Naturals1997-04-012006-09-20Canada
Dexatrim TabletsTabletOralChattem, Inc.1996-09-092005-06-29Canada
Dia-viteTabletOralR & D Laboratories Inc.1997-08-132003-07-16Canada
DiaplexTabletOralNephro Tech, Inc.2002-07-102004-07-23Canada
Dinosaurs Im-rapWaferOralNutraceutical CorporationNot applicableNot applicableCanada
Dual MixPowderOralOmnilife Manufactura, S.A. De C.V.2003-11-032008-08-20Canada
Dynam Ampoule Et TabletLiquid; TabletOralCardinaux Enrg Les Produits Naturels1989-12-311996-09-09Canada
E.S.T. ComplexTabletOralAbundance Marketing Ltd.2000-12-062004-06-30Canada
E.V.C. Vitamins TabTabletOralSisu Inc.1985-12-312009-08-04Canada
EC + ComplexCapsuleOralSeroyal International Inc.1998-12-312009-07-06Canada
Efferlife Calcium 500mg + Vitamin D3 440 Iu + Vitamin C 125mgTablet, effervescentOralNaturale Science Inc.2001-10-012006-10-10Canada
Efferlife Multivitamins and MineralsTablet, effervescentOralNaturale Science Inc.2001-10-012006-10-10Canada
Effervescent Vitamin C Powder With Ca and mgPowderOralThorne Research Inc.1997-04-182005-06-21Canada
Eky Efferlife Vitamin C 1000mg With ZincTablet, effervescentOralNaturale Science Inc.2003-06-212006-10-10Canada
EnBrace HRCapsule, delayed release pelletsOralJaymac Pharmaceuticals, Llc2015-04-08Not applicableUs
Energy 80 Prolonged Release TabTablet, extended releaseOralSportscience Labs Inc.1981-12-312002-06-20Canada
EnLyteCapsule, delayed release pelletsOralJaymac Pharmaceuticals Llc2011-10-01Not applicableUs
Enviroflex - TabTabletOralEnviro Tech International Canada1997-09-151999-07-26Canada
EnviveCapsuleOralSisu Inc.2002-04-012006-07-31Canada
EnzogenolCapsuleOralSisu Inc.2003-02-022008-07-25Canada
EscaviteTablet, chewableOralGm Pharmaceuticals2012-02-01Not applicableUs
Ester C 500 TabTabletOralNu Life Nutrition Ltd.1997-08-152005-03-15Canada
Ester C Calcium Ascorbate CapCapsuleOralNatrol, Inc.1991-12-312007-10-01Canada
Ester C CapsuleCapsuleOralNatural Factors Nutritional Products Ltd.1998-01-222002-04-23Canada
Ester C PowderPowderOralNatural Factors Nutritional Products Ltd.1997-12-232001-07-26Canada
Ester C Tab ChewableTabletOralNatrol, Inc.1991-12-312001-07-30Canada
Ester C Vitamin C and Calcium PwsPowder, for solutionOralNatrol, Inc.1990-12-312007-10-01Canada
Ester-CCapsuleOralNatural Factors Nutritional Products Ltd.2002-04-232008-07-17Canada
Ester-C 500 mgTabletOralWn Pharmaceuticals Ltd.2000-05-102008-07-17Canada
Ester-C 600 mgCapsuleOralWn Pharmaceuticals Ltd.2000-06-012007-08-07Canada
Ester-C 787mgCapsuleOralNatural Factors Nutritional Products Ltd.2004-01-202008-07-17Canada
Ester-C Calcium Ascor TabTabletOralNatrol, Inc.1991-12-312007-10-01Canada
Ester-C Calcium Ascorbate CapsulesCapsuleOralSwiss Herbal Remedies Ltd.1995-12-312009-08-04Canada
Ester-C Calcium Ascorbate TabTabletOralNatrol, Inc.1991-12-312001-07-30Canada
Ester-C Calcium Ascorbate TabletsTabletOralSwiss Herbal Remedies Ltd.1995-12-312009-08-04Canada
Ester-C PowderPowderOralNatural Factors Nutritional Products Ltd.2000-05-162002-08-02Canada
Ester-C TabletTabletOralNatural Factors Nutritional Products Ltd.1999-12-062003-07-22Canada
Ester-C Vitamin C With CalciumCapsuleOralDarwen Holdings Ltd.Not applicableNot applicableCanada
Evc - LiqLiquidOralSisu Inc.1994-12-312007-07-20Canada
Evc Liquid Vitamins A,c,b6 With Beta Caro&znLiquidOralNf Formulas Inc.1992-12-312008-06-26Canada
Everyday Multiple VitaminsTabletOralD.C. Labs Limited1972-12-312003-07-11Canada
Everyday Multiple Vitamins With IronTabletOralD.C. Labs Limited1972-12-312003-07-11Canada
Extra P.N. Vitamin-mineral Drink MixPowderOralChanges InternationalNot applicableNot applicableCanada
Extra Strength PharmacitronPowderOralPharmascience IncNot applicableNot applicableCanada
Extra-Virt Plus DHACapsule, gelatin coatedOralVirtus Pharmaceuticals2012-12-28Not applicableUs
FE C TabTabletOralBoca Pharmacal, Inc.2010-08-192017-11-30Us
FE C Tab PlusTabletOralBoca Pharmacal, Inc.2011-03-312015-12-29Us
Fem - ControlTabletOralMetagenics, Inc.1998-01-312005-08-19Canada
Fem - PmtTabletOralMetagenics, Inc.1998-02-252002-10-07Canada
Feminex 300 TabTabletOralSantÉ Naturelle (Ag) LtÉe1986-12-311997-09-09Canada
Feminique W Iron and Calcium TabTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1992-12-311998-08-13Canada
Femitab TabTabletOralLe Groupe Prodeal Ltee1988-12-312009-08-05Canada
FeRivaCapsuleOralAvion Pharmaceuticals, Llc2012-12-30Not applicableUs
FeRiva FACapsule, gelatin coatedOralAvion Pharmaceuticals, Llc2014-12-18Not applicableUs
FeRivaFACapsule, gelatin coatedOralAvion Pharmaceuticals, Llc2014-01-02Not applicableUs
Fero Grad 500Tablet, extended releaseOralAbbott1961-12-311999-08-09Canada
Ferra Naka Plus VitaminsLiquidOralNaka Sales Ltd.1999-05-052001-07-23Canada
Ferralet 90Tablet, film coatedOralMission Pharmacal2010-02-042017-08-24Us
Fib-C MeltsTabletOralApm Products Pty Ltd.2003-08-152004-09-10Canada
Flinstones Multiple Plus IronTabletOralMiles Inc. Pharmaceutical Division1971-12-311996-09-09Canada
Flintstones Multiple VitaminsTabletOralBayer Inc Consumer Care1995-12-312004-06-28Canada
Flintstones Multiple Vitamins Plus IronTabletOralBayer Inc Consumer Care1995-12-312004-06-28Canada
Flintstones Multiple Vitamins TabTabletOralMiles Inc. Pharmaceutical Division1970-12-311996-09-09Canada
Flintstones W Extra C TabTabletOralMiles Inc. Pharmaceutical Division1981-12-311996-09-09Canada
Floravit - SyrSyrupOralFlora Manufacturing And Distributing Ltd.1995-05-282009-08-05Canada
FlorivaTablet, chewableOralBon Geo Pharmaceuticals, Inc.2015-09-10Not applicableUs
Floriva PlusSolution / dropsOralBon Geo Pharmaceuticals, Inc.2015-12-28Not applicableUs
Folcal DHACapsule, gelatin coatedOralMidlothian Laboratories2010-12-01Not applicableUs
Folcaps Care OneCapsule, gelatin coatedOralMidlothian Laboratories2009-05-01Not applicableUs
Folcaps Omega-3Capsule, gelatin coatedOralMidlothian Laboratories2011-01-03Not applicableUs
Folet OneCapsule, liquid filledOralPronova Corporation2014-06-01Not applicableUs
Folic Acid & Vitamin CTabletOralHolista Health (Canada) Inc.2003-02-052006-08-02Canada
Folic Acid 1mg With C 20mgTabletOralGahler Enterprises Ltd.1986-12-312006-07-26Canada
Folic Acid 1mg With Vitamin CTabletOralWn Pharmaceuticals Ltd.1998-09-142007-08-07Canada
Folic Acid PlusTabletOralVita Health Products Inc2000-04-012002-07-31Canada
Folic Acid With Vitamin B12 and Vitamin CCapsuleOralFlora Manufacturing And Distributing Ltd.2003-12-312009-08-05Canada
Folivane-PRx DHACapsuleOralTrigen Laboratories, Inc.2010-01-01Not applicableUs
Foltabs PrenatalTabletOralMidlothian Laboratories2009-01-01Not applicableUs
For Kids Only Chewable Multivit. Plus IronTabletOralKsl Pharmaceuticals1996-12-312002-07-31Canada
For Kids Only Chewable Multivitamins - TabTabletOralKsl Pharmaceuticals1996-12-312002-07-31Canada
Formula 14 Dietary SupplementCapsuleOralRx Vitamins Inc.2004-12-062007-10-25Canada
Formula A.R.-th Dietary SupplementCapsuleOralRx Vitamins Inc.2004-04-042007-10-25Canada
Formula BCapsuleOralBalance Plus, Inc.2000-04-192004-08-17Canada
Formula CFCapsuleOralKroeger Herb ProductsNot applicableNot applicableCanada
Formula CnCapsuleOralBalance Plus, Inc.2000-02-092004-08-17Canada
Formula Csp With Vitamins A C and Zinc LozLozengeOralQuantum, Inc.1997-09-172005-08-01Canada
Formula CwTabletOralBody Wise International LlcNot applicableNot applicableCanada
Formula Cw-capletTabletOralBody Wise International Llc1995-12-312005-10-24Canada
Formula Fm Vitamins & Minerals TabTabletOralMetagenics, Inc.1997-01-272001-10-05Canada
Formula Im-vitamins and Minerals TabTabletOralMetagenics, Inc.1997-01-272006-08-14Canada
Formula Imgrd - TabTabletOralHealth Wise Nutrition Inc.1997-08-152002-07-18Canada
Formula InfCapsuleOralBalance Plus, Inc.2000-02-092004-08-17Canada
Formula LfTabletOralNumark Laboratories, Inc.2003-12-152009-07-31Canada
Formula No. 2 Plus K LiqLiquidOralGolden Pride/Rawleigh1993-12-311996-09-30Canada
Formula OCapsuleOralGeneral Nutrition Canada Inc.1997-09-122005-08-05Canada
Formula OsgTabletOralSeroyal International Inc.1994-12-312000-08-08Canada
Formula R TabTabletOralMetagenics, Inc.1997-03-052006-08-29Canada
Formule 7561 CapsCapsuleOralTherapeutic Foods Co.1990-12-312005-07-20Canada
Formule No 204 Profil TabTabletOralPharmalab Inc.1987-12-312001-07-30Canada
Fortamines 10 CapsulesCapsuleOralRougier Pharma Division Of Ratiopharm Inc1974-12-311999-09-27Canada
Fortamines-10 ComprimesTabletOralRougier Pharma Division Of Ratiopharm Inc1979-12-312003-09-22Canada
Fortifi-plusCapsuleOralClinique Lafontaine Inc, Division Les Importations Ortho1998-01-222008-08-07Canada
Fortistress TabTabletOralSantÉ Naturelle (Ag) LtÉe1993-12-312001-07-06Canada
Forty Plus Vitamin SupplementTabletOralGarden State Nutritionals1998-10-162000-06-07Canada
Fusion Activator Formula TabTabletOralL & S Research Corporation1993-12-311996-09-09Canada
G.A.S. ComplexTabletOralAbundance Marketing Ltd.2000-12-062004-06-30Canada
Garfield Chewable Multivits Plus Iron TabTabletOralWhitehall Robins Inc.1993-12-312000-07-26Canada
Gemvites Jr Tab ChewableTabletOralPharmavite Laboratories (1987) Inc.1969-12-311999-10-19Canada
Gestamine ComprimesTabletOralLab Nadeau LtÉe, Division Of Technilab Inc.1957-12-311999-09-28Canada
Gesticare DHAKitJazz Pharmaceuticals Commercial Corp.2008-10-01Not applicableUs
Glyco-aide TabTabletOralAvant Garde, Les SupplÉments1995-12-311998-07-08Canada
Golf Vitamin and Mineral SupplementLiquidOralMuscle Marketing Usa Inc.2001-02-242008-06-27Canada
Good Night/pm Formula TabTabletOralNikken Usa, Incorporated1995-12-312002-06-26Canada
Grippalin & C TabTabletOralDistributions Multi Pro Inc.1988-12-312000-08-02Canada
Guardyn TabTabletOralNutri Dyn Products Ltd.1986-12-311998-08-13Canada
healthy mamaBE WELL ROUNDED BE WELL ROUNDEDTablet, film coatedOralMATERNAL SCIENCE, LLC2013-07-09Not applicableUs
Hemarexin TabTabletOralLab Bio Chimique Inc.,Division Of Technilab Pharma Inc.1997-12-172004-08-03Canada
HematogenCapsuleOralNnodum Pharmaceuticals2007-05-10Not applicableUs63044 0631 19 nlmimage10 23409194
Hematogen FACapsuleOralNnodum Pharmaceuticals2005-01-01Not applicableUs
Hematogen ForteCapsule, gelatin coatedOralNnodum Pharmaceuticals2007-05-10Not applicableUs
Hi Potency B52 B Complex TabTabletOralCountry Health Laboratories Ltd.1982-12-312001-07-27Canada
Hi Potency Stress B Tension With CTabletOralLee Adams Laboratories1982-12-312010-08-05Canada
High Potency Vitamin B Complex + C TabTabletOralVita Health Products Inc1996-10-112004-07-26Canada
Hill.viteTabletOralHillestad Pharmaceuticals Usa2001-11-142009-09-22Canada
Homosistrol CapsulesCapsuleOralMacromed Pharmicia Inc.Not applicableNot applicableCanada
Hot Lemon Cold and Flu Relief Extra StrengthPowderOralPharmanutrients Botanical CorporationNot applicableNot applicableCanada
Hot Lemon Cold and Flu Relief Regular StrengthPowderOralPharmanutrients Botanical CorporationNot applicableNot applicableCanada
Hot Lemon Extra StrengthKit; PowderOralProdemdis Enr.1997-04-152010-07-15Canada
Hot Lemon for Colds PowderPowder, for solutionOralRandle Pharmaceutical Inc.1989-12-311997-05-30Canada
Hot Lemon Regular - PwrKit; PowderOralProdemdis Enr.1997-04-152010-07-15Canada
Hot Lemon Relief Pck-pwsKit; Powder, for solutionOralApotex Corporation1996-11-26Not applicableCanada
Hot Lemon Relief - Extra StrengthPowderOralJamp Pharma Corporation2001-12-29Not applicableCanada
Hot Lemon Relief for Cold Symptoms Ext StrPowder, for solutionOralPatheon Laboratories1992-12-312001-09-01Canada
Hot Lemon Relief for Cold Symptoms PwsPowder, for solutionOralPatheon Laboratories1992-12-312000-09-25Canada
Hot Lemon Relief for Symptoms Of Cold and FluPowderOralCellchem Pharmaceuticals Inc.Not applicableNot applicableCanada
Hot Lemon Relief for Symptoms Of Cold and Flu Extra StrengthPowderOralPharmetics (2011) Inc.2001-09-01Not applicableCanada
Hot Lemon Relief for Symptoms Of Cold and Flu FortePowderOralPharmetics (2011) Inc.Not applicableNot applicableCanada
Hot Lemon Relief for Symptoms Of Cold and Flu Regular StrengthPowderOralPharmetics (2011) Inc.1999-01-06Not applicableCanada
Hot Lemon Relief for Symptoms Of Cough and ColdPowder, for solutionOralPharmetics (2011) Inc.1995-12-31Not applicableCanada
Hot Lemon Relief PowderPowderOralJamp Pharma Corporation2006-04-28Not applicableCanada
Hot Lemon Relief Powder Extra StrengthPowderOralNutralife Health Products Ltd.Not applicableNot applicableCanada
Hot Lemon Relief Powder Regular StrengthKit; PowderOralNutralife Health Products Ltd.Not applicableNot applicableCanada
Hot Lemon Relief Regular StrengthPowderOralJamp Pharma Corporation2001-12-29Not applicableCanada
Hot Lemon Relief-extra Strength Pck-pwsKit; Powder, for solutionOralApotex Corporation1996-11-26Not applicableCanada
Hvp Chelated Cal/mag With Zinc and Vitamins C and DTabletOralDarwen Holdings Ltd.Not applicableNot applicableCanada
Hypo Vites TabTabletOralPharmetics (2011) Inc.1977-12-312006-07-27Canada
I-care Multivitamin and Multimineral TabletsTabletOralPharmetics (2011) Inc.2002-05-302009-07-30Canada
Iberet 500Tablet, extended releaseOralAbbott1965-12-312007-07-31Canada
IcapsTabletOralAlcon, Inc.1994-12-312009-04-24Canada
Icaps Time ReleaseTabletOralAlcon, Inc.1997-06-202001-08-14Canada
ImedeenTabletOralNordic Selfcare Institute P Technologies Int'l (Pti) Inc.1998-06-302000-02-09Canada
Imm FormulaTabletOralAbundance Naturally LtdNot applicableNot applicableCanada
Imm Formula CapCapsuleOralNatures Sunshine Products, Inc.1990-12-312001-07-31Canada
Inatal AdvanceTablet, coatedOralNnodum Pharmaceuticals2005-06-10Not applicableUs
INATAL UltraTablet, coatedOralNnodum Pharmaceuticals2005-06-20Not applicableUs
Infa Drops MultivitaminsLiquidOralVita Health Products Inc1998-05-202002-07-31Canada
Infant Multivitamin DropsSolution / dropsOralGeneral Nutrition Canada Inc.2002-10-202005-08-05Canada
Infant's Multiple Vitamin DropsLiquidOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1991-12-312002-07-31Canada
Infantol DropsSolution / dropsOralChurch & Dwight Company, Inc.1988-12-312008-07-30Canada
Infants' Vitamin DropsSolution / dropsOralKsl Pharmaceuticals1991-12-311998-08-13Canada
Infuvite Adult Multiple VitaminsInjection, solutionIntravenousSandoz2005-05-18Not applicableUs
Insur-all Vitamin SupplementTabletOralGarden State Nutritionals1998-10-162000-06-07Canada
Integra FCapsuleOralUs Pharmaceutical Corporation2009-04-27Not applicableUs
Integra PlusCapsuleOralUs Pharmaceutical Corporation2009-04-27Not applicableUs
Iron 25mg With Vit B-cmplx, Vit C, Cu & MoCapsuleOralQuest Vitamins A Div Of Purity Life Health Products1996-07-232002-07-29Canada
Iron ComplexTabletOralPremier Plus Supplements Inc.2000-04-252003-07-16Canada
Iron Plus Manganese, B12, Folic Acid & CTabletOralNatural Factors Nutritional Products Ltd.1988-12-312005-08-15Canada
Iron Plus TabTabletOralSwiss Herbal Remedies Ltd.1973-12-312008-08-15Canada
Iron Polysaccharides Folic Acid DHATablet, film coatedOralVirtus Pharmaceuticals2013-12-202017-08-11Us
Iron Vitamins B6,b12,c,folic Acid TabTabletOralLaboratoire Lalco Inc.1989-12-311997-07-31Canada
Itabs PlusTabletOralVita Health Products Inc2000-01-012002-07-31Canada
J.T. FormulaTabletOralChanges InternationalNot applicableNot applicableCanada
Kama Caze SyrupSyrupOralAlbi Naturals1996-12-312008-07-17Canada
Kanga Sport Vitamins B & C Plus MineralsTablet, effervescentOralLacombe Drugs (1992) LtdNot applicableNot applicableCanada
Kanga-B Vitamin B Group + CTablet, effervescentOralLacombe Drugs (1992) LtdNot applicableNot applicableCanada
Kanga-kid Multi-vitamin & MineralTablet, effervescentOralLacombe Drugs (1992) LtdNot applicableNot applicableCanada
Kanga-V Multivitamins & MineralsTablet, effervescentOralLacombe Drugs (1992) LtdNot applicableNot applicableCanada
Kenwood Liquid SupplementLiquidOralKenwood Laboratories (Division Of Bradley Pharmaceuticals)Not applicableNot applicableCanada
Kid's Choice Children's Chewable Vitamins - TabTabletOralVita Health Products Inc1998-04-162002-07-31Canada
Kidmag Vitamins W Magnesium TabTabletOralMetagenics, Inc.1989-12-311996-10-02Canada
Kids Stuff TabletsTabletOralVita Health Products Inc1998-04-202002-07-31Canada
Kids Stuff With Iron TabletsTabletOralVita Health Products Inc1998-04-202002-07-31Canada
Kimchi Vitamin chewable multivitaminTablet, chewableOralTobico2010-03-18Not applicableUs
KindervitesSolution / dropsOralHerbalife International Of America1984-12-312002-09-17Canada
L.G.I.T.CapsuleOralMorinda Canada1999-12-152001-07-23Canada
L.I.P. ComplexTabletOralAbundance Marketing Ltd.2000-12-062004-06-30Canada
Lemon TimePowderOralNovartis1990-12-312003-07-28Canada
Leritone JuniorCapsuleOralInstitut De Recherche Biologique Yves Ponroy Canada Inc.1998-12-072004-12-23Canada
Lipo-B-C TabTabletOralMetagenics, Inc.1989-12-311996-10-02Canada
Liqui Infant VitaminsLiquidOralTwin Laboratories Inc.1995-12-311999-11-10Canada
Liqui VitaLiquidOralTwin Laboratories Inc.1995-12-311999-11-10Canada
Livron Plus TabTabletOralMedic Laboratory LtÉe1980-12-311996-09-09Canada
Lysamine Diet Supp Amp-tabLiquid; TabletOralWelcker Lyster Ltd., Division Of Technilab Inc.1983-12-311999-09-17Canada
M.V.I. 12LiquidIntravenousAventis Pharma Ltd.1992-12-312002-07-29Canada
M.V.I. PaediatricLiquidIntravenousAventis Pharma Ltd.1988-12-312002-07-29Canada
M.V.I. PediatricInjection, powder, lyophilized, for solutionIntravenousHospira Worldwide, Inc.1983-04-06Not applicableUs
MacuzinCapsuleOralSterling Knight Pharmaceuticals, Llc2015-04-302017-09-13Us
MangadynTabletOralNutri Dyn Products Ltd.1982-12-311997-08-22Canada
Maxaron ForteCapsuleOralCentrix Pharmaceutical2007-12-012016-12-02Us
MaxFeTabletOralPronova Corporation2014-06-01Not applicableUs
Maxi 10 TabTabletOralDesbergers LtÉe, Division Of Technilab Inc.1979-12-311999-09-17Canada
Maxi 6 LiqLiquidOralDesbergers LtÉe, Division Of Technilab Inc.1980-12-311999-09-17Canada
Mega 13 Multivitamin FormulaCapsuleOralVita Health Products Inc1988-12-311998-07-22Canada
Megavites TabTabletOralIcn Pharmaceuticals1973-12-312005-04-26Canada
Meplex T 750TabletOralMedic Laboratory LtÉe1966-12-311996-09-09Canada
Metreton TabTabletOralSchering Plough1956-12-312007-08-03Canada
Milk Calcium With Vitamins C, D, and PhosphorousTabletOralQuest Vitamins A Div Of Purity Life Health Products2000-10-012006-07-25Canada
Mor-vites TabTabletOralPharmetics (2011) Inc.1992-12-312006-07-27Canada
MoviprepPowder, for solutionOralMedical Futures Inc2011-04-28Not applicableCanada
Mr. Tumee Multi-vitaminTablet, chewableOralVitamec Usa2003-04-152006-09-29Canada
Multi - N.T.O.x Formula - TabTabletOralAbundance Naturally LtdNot applicableNot applicableCanada
Multi 12 InjectionLiquidIntravenousSandoz Canada Incorporated1994-12-31Not applicableCanada
Multi Enfants TabTabletOralVitalab1992-12-311997-07-22Canada
Multi Nt-OXTabletOralAbundance Marketing Ltd.1999-02-012001-07-10Canada
Multi Vitamin - MineralTabletOralEnrich International1999-11-112001-09-28Canada
Multi Vitamin & MineralsTabletOralWn Pharmaceuticals Ltd.2002-01-042008-07-17Canada
Multi Vitamin and FluorideSolution / dropsOralLibertas Pharma, Inc.2011-05-21Not applicableUs
Multi Vitamin Drops with FluorideSolution / dropsOralSeton Pharmaceuticals2014-04-18Not applicableUs
Multi Vitamin Drops with Fluoride and IronSolution / dropsOralSeton Pharmaceuticals2014-04-18Not applicableUs
Multi Vitamin Drops with Fluoride with IronLiquidOralStratus Pharmaceuticals2014-09-01Not applicableUs
Multi Vitamin Plus IronTabletOralWn Pharmaceuticals Ltd.2002-03-132009-09-28Canada
Multi Vitamin with FluorideTablet, chewableOralQualitest2009-10-092016-10-13Us
Multi Vitamin-mineral FormulaTabletOralVita Health Products Inc1997-04-031998-01-16Canada
Multi Vitamin, Iron and FluorideSolution / dropsOralMayne Pharma2011-05-212019-10-31Us
Multi Vitamines - LiqLiquidOralLand Art Inc.1995-12-312008-06-26Canada
Multi Vitamins & MineralsTabletOralWn Pharmaceuticals Ltd.2000-01-122001-04-12Canada
Multi Vite Liq JuniorLiquidOralPharmetics (2011) Inc.1981-12-312001-07-26Canada
Multi-11SolutionIntravenousSandoz Canada Incorporated2002-01-28Not applicableCanada
Multi-12 PediatricLiquidIntravenousSabex Inc1998-04-092009-11-26Canada
Multi-12/k1 PediatricLiquidIntravenousSandoz Canada Incorporated2000-11-07Not applicableCanada
Multi-fruits Chewable Vitamin C 500mg TabletTabletOralWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.1994-12-311997-08-11Canada
Multi-min Electro C Pow Plus B2Granule, effervescentOralQuest Vitamins A Div Of Purity Life Health Products1988-12-311998-07-15Canada
Multi-Vit with FluorideSolutionOralA S Medication Solutions1997-04-182017-06-20Us
Multi-Vit with Fluoride and IronSolutionOralQualitest1998-01-07Not applicableUs
Multi-VitaminLiquidOralLLC Federal Solutions2013-08-12Not applicableUs
Multi-vitamin Dietary SupplementTabletOralGarden State Nutritionals1998-09-222000-06-07Canada
Multi-Vitamin Drops with Fluoride and IronLiquidOralMethod Pharmaceuticals2017-02-24Not applicableUs
Multi-Vitamin FluorideLiquidOralStratus Pharmaceuticals2014-09-01Not applicableUs
Multi-Vitamin Fluoride and Iron DropsSolutionOralBoca Pharmacal, Inc.2011-04-202015-12-29Us
Multi-Vitamin Fluoride DropsSolutionOralH.J. Harkins Company2011-05-04Not applicableUs
Multi-Vitamin With FluorideTablet, chewableOralGolden State Medical Supply2010-12-17Not applicableUs
Multi-vitamines Enfants ComprimeTabletOralHerbes Universelles Inc.1997-09-292009-07-15Canada
Multi-vitaminsTabletOralWn Pharmaceuticals Ltd.1999-12-222008-07-17Canada
Multi-vitamins With MineralsTabletOralWn Pharmaceuticals Ltd.2001-04-122009-09-28Canada
Multiple Vitamin Plus Minerals TabTabletOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Multiple Vitamin TabTabletOralAdams Laboratories1983-12-312009-12-02Canada
Multiple VitaminsTabletOralGfr Pharma Ltd.2002-10-102007-07-20Canada
Multiple Vitamins & Minerals TabletsTabletOralPharmetics (2011) Inc.2002-12-182006-07-27Canada
Multiple Vitamins and Minerals TabTabletOralRandle Pharmaceutical Inc.1987-12-311997-05-30Canada
Multiple Vitamins Plus Iron for WomenTabletOralPharmetics (2011) Inc.1999-08-162006-07-27Canada
Multiple Vitamins Plus Iron TabTabletOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Multiple Vitamins TabTabletOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Multiple Vitamins W Minerals TabTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1976-12-312002-07-31Canada
Multiple Vitamins With IronTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1987-12-312002-07-31Canada
Multiple Vitamins With Minerals TabletsTabletOralPharmetics (2011) Inc.1999-07-162009-07-30Canada
Multivit Et Fer Ampoules Et ComprimesLiquid; TabletOralNobel Pharm Enr.1988-12-311998-08-14Canada
MultivitaminTabletOralLaboratoires Confab IncNot applicableNot applicableCanada
Multivitamin Drops with FluorideSolution / dropsOralSancilio & Company, Inc.2017-04-10Not applicableUs
MultiVitamin Drops with Fluoride and IronLiquidOralSancilio & Company, Inc.2017-08-24Not applicableUs
Multivitamin with fluorideTablet, chewableOralA S Medication Solutions2011-12-202017-06-20Us
MultivitaminesTabletOralRolmex International Inc.1998-05-112007-07-09Canada
Multivitamines Et MinerauxTabletOralLe Groupe M. Vachon Inc.Not applicableNot applicableCanada
Multivitamines Et Mineraux Junior RegulierTabletOralLaboratoire Riva Inc1996-10-082008-07-30Canada
Multivitamines Et Mineraux Reguliers / Regular Multivitamins and MineralsTabletOralVita Health Products Inc1998-10-062004-07-26Canada
Multivitamines Plus Fer Pour Enfants (chewable Tablets)TabletOralLaboratoire Lalco Inc.1998-07-032002-09-05Canada
Multivitamines Pour Enfants (chewable Tablets)TabletOralLaboratoire Lalco Inc.1998-07-032002-09-05Canada
Multivitamins and Minerals - CompleteTabletOralVita Health Products Inc2000-02-012006-07-31Canada
Multivitamins and Multiminerals Formula Regular TabletTabletOralPharmetics (2011) Inc.2001-11-222009-07-30Canada
Multivitamins for ChildrenTabletOralQuest Vitamins A Div Of Purity Life Health Products2001-01-312004-06-29Canada
Multivitamins W IronTabletOralRandle Pharmaceutical Inc.1987-12-311997-05-30Canada
Munit-E TabletTabletOralHolista Health (Canada) Inc.1996-12-312002-08-06Canada
MvcTablet, chewableOralSancilio & Company Inc.2009-12-20Not applicableUs
MVC-FluorideTablet, chewableOralSancilio & Company Inc.2011-12-07Not applicableUs
Myhephron Dialysis and Stress SupplementCapsuleOralMartin Ekwealor Pharmaceu2016-08-01Not applicableUs
Mynephrocaps Dialysis/stress Vitamin SupplementCapsuleOralMartin Ekwealor Pharmaceuticals, Inc.2013-12-16Not applicableUs
N.E.U. ComplexTabletOralAbundance Marketing Ltd.2000-12-042004-06-30Canada
N.U.T. ComplexTabletOralAbundance Marketing Ltd.2000-12-062004-06-30Canada
Nata KompleteTabletOralWh Nutritionals, Llc2011-06-252016-12-06Us
NataFortTabletOralMission Pharmacal2011-08-25Not applicableUs
NataviteTabletOralSchein Pharmaceutical Canada Inc.1997-07-292004-07-26Canada
Natelle OneCapsule, gelatin coatedOralMeda Pharmaceuticals Ltd2015-02-01Not applicableUs
Natura Magnesium Plus Vitamin CLiquidOralNaka Sales Ltd.1996-07-271999-11-26Canada
Neo Citran A PowderPowderOralNovartis1991-12-312004-07-21Canada
Neo Citran PowderPowderOralNovartis1991-12-312004-07-21Canada
Neo Vites TabTabletOralNeolab Inc1979-12-311997-08-12Canada
Neo-vites & Minerals TabTabletOralNeolab Inc1987-12-311997-08-12Canada
NephrocapsCapsule, liquid filledOralCardinal Health2010-01-14Not applicableUs
Nestabs ONECapsule, gelatin coatedOralWomens Choice Pharmaceuticals, Llc2017-07-20Not applicableUs
Neutral C + Coenzyme Q10 - CapCapsuleOralNew Vision Nutritionals CompanyNot applicableNot applicableCanada
Neutral C + Coenzyme Q10 Plus Vitamins & MineralsCapsuleOralNew Vision Nutritionals Company1998-06-072002-11-20Canada
Nexa PlusCapsuleOralUpsher Smith Laboratories2012-08-01Not applicableUs
Nexa Select Rx Prenatal Vitamin with Plant-Based DHACapsuleOralUpsher Smith Laboratories2012-12-17Not applicableUs
Niacinamide 250mg With 50mg CTabletOralGahler Enterprises Ltd.1987-12-312000-08-01Canada
Niacinamide 250mg With Vitamin CCapsuleOralAlbi Naturals1999-04-302008-07-17Canada
NiferexTabletOralAvion Pharmaceuticals, Llc2017-01-23Not applicableUs
Nighttime Extra Strength Contac Complete Cough, Cold & Flu Plus Vitamin CTabletOralGlaxosmithkline IncNot applicableNot applicableCanada
Niron KompleteTabletOralWh Nutritionals, Llc2011-06-252016-12-06Us
No440 CapCapsuleOralHerbes Universelles Inc.1976-12-312009-07-15Canada
NuFeraTabletOralCarwin Associates, Inc2015-12-16Not applicableUs
Nutrifer Plus TabletsTabletOralWyeth Ayerst Canada Inc.1994-12-311999-09-23Canada
Nutrilite Double XTabletOralNutrilite, A Division Of Access Business Group, Llc2002-12-152008-06-24Canada
O-Cal FA multivitaminTabletOralPharmics, Inc.1970-01-15Not applicableUs
O-Cal Prenatal VitaminTabletOralPharmics, Inc.2002-01-23Not applicableUs
ObagiLiquidTopicalYS PLUS CORPORATION2014-10-012017-06-20Us
OcuvelCapsuleOralAdler Stern Pharmaceuticals, Llc2014-11-05Not applicableUs
Ocuvite Vitamin and Mineral SupplementTabletOralBausch & Lomb Inc2003-07-302006-08-02Canada
Ocuvite Vitamin and Mineral Supplement CapsulesCapsuleOralBausch & Lomb Inc2001-10-312006-08-02Canada
OnccorTabletOralSimone Protective Pharmaceuticals, Inc.Not applicableNot applicableCanada
One A Day Advance AdultsTabletOralBayer Inc Consumer Care2002-09-122007-08-02Canada
One A Day Advance Adults 50+TabletOralBayer Inc Consumer Care2002-09-122007-08-02Canada
One A Day Advance FemTabletOralBayer Inc Consumer Care1999-03-012001-02-22Canada
One A Day TabTabletOralCountry Health Laboratories Ltd.1982-12-312001-07-27Canada
One A Day With Non-medicinal EchinaceaTabletOralBayer Inc Consumer Care2000-09-272002-08-01Canada
Opti-manganese + B1 + C CapletTabletOralNu Life Nutrition Ltd.1991-12-312005-03-15Canada
Optivite Vitamin and Mineral Supplement TabletTabletOralPharmetics (2011) Inc.1998-11-102005-08-04Canada
Orange Flavored Crystal Chews TabTabletOralJeunique International Inc.1998-02-172006-07-20Canada
Orifer FTabletOralSanofi Aventis1995-12-312007-11-22Canada
Original Bioscal Forte Multi-vitamin Supplement CapsulesCapsuleOralCarram Inc.1997-05-071999-07-30Canada
Osteo Formula TabTabletOralQuest Vitamins A Div Of Purity Life Health Products1994-12-312006-07-25Canada
Osteo TabletsTabletOralQuest Vitamins A Div Of Purity Life Health Products1995-12-312000-07-20Canada
P.N.P. Vitamin DrinkLiquidOralChanges InternationalNot applicableNot applicableCanada
P.R.O. ComplexTabletOralAbundance Marketing Ltd.2000-12-062004-06-30Canada
Paramettes Chewable Multivitamins Plus IronTabletOralWyeth Ayerst Canada Inc.1994-12-312000-08-02Canada
Paramettes Chewable Multivits With Iron TabTabletOralWhitehall Robins Inc.1994-12-311996-09-09Canada
Paramettes Multivits Plus Iron Tab (teens)TabletOralWhitehall Robins Inc.1993-12-311996-09-09Canada
Paramettes SyrupSyrupOralWyeth Ayerst Canada Inc.1994-12-312002-07-31Canada
Pediatric Infuvite Multiple VitaminsInjection, solutionIntravenousSandoz2001-02-21Not applicableUs
Pediatric Infuvite Multiple Vitamins for InfusionInjection, solutionIntravenousSandoz2001-02-21Not applicableUs
Penta-thion PwrPowderOralSabex Inc1994-12-312008-08-07Canada
Perfect HarvestTabletOralGood Times Merchandising & Licensing Corp.1997-04-212002-09-26Canada
Permathene-12 - CapletTabletOralCca Industries, Inc1995-12-312000-12-14Canada
PharmacitronPowderOralPharmascience IncNot applicableNot applicableCanada
Phytoplex B LiqLiquidOralPhyto Health Corporation1973-12-312004-08-30Canada
PhytopureCapsuleOralLaboratoire Lalco Inc.1993-12-312001-10-15Canada
PM CapsCapsuleOralNew Vision Nutritionals Company1998-10-012002-11-20Canada
Pneumodyn TabTabletOralNutri Dyn Products Ltd.1976-12-311996-09-09Canada
PNV Ferrous Fumarate Docusate Folic AcidTabletOralVirtus Pharmaceuticals2014-04-22Not applicableUs
PNV Prenatal Plus MultivitaminTabletOralClinical Solutions Wholsesale2013-04-012017-07-03Us
PNV Prenatal VitaminTablet, chewableOralSancilio & Company Inc.2011-12-20Not applicableUs
PNV Prenatal Vitamin Plus Vitamin ATabletOralSancilio & Company Inc.2012-12-07Not applicableUs
Pnv-dhaCapsule, gelatin coatedOralAcella Pharmaceuticals, LLC2009-11-02Not applicableUs
PNV-FirstTablet, coatedOralAcella Pharmaceuticals, LLC2013-05-17Not applicableUs
PNV-SelectTablet, film coatedOralAcella Pharmaceuticals, LLC2009-11-02Not applicableUs
Poly-VI-sol DropsLiquidOralMead Johnson Nutritionals1986-12-312000-09-11Canada
Polymine Avec Zinc Et CuivreTabletOralLes Laboratoires Vachon Inc.1985-12-312007-07-12Canada
Powertech Vitamin and Mineral SupplementPowderOralDymatize Enterprises Inc.2002-09-182006-10-06Canada
PreferaOB ONECapsule, liquid filledOralMeda Pharmaceuticals Ltd2015-04-28Not applicableUs
PregvitTabletOralDuchesnay Inc.2003-08-252016-07-05Canada
Pregvit Folic 4TabletOralDuchesnay Inc.Not applicableNot applicableCanada
Pregvit Folic 5TabletOralDuchesnay Inc.2006-03-172016-07-05Canada
PrenaissanceCapsule, liquid filledOralAcella Pharmaceuticals, LLC2011-05-192017-09-08Us
PreNatal 19Tablet, coatedOralNationwide Laboratories2013-06-01Not applicableUs
Prenatal Mega AntioxidantTabletOralUsana Health Services, Inc.2012-04-11Not applicableUs
Prenatal PlusTablet, film coatedOralBlenheim Pharmacal, Inc.2010-12-09Not applicableUs65162 0668 50 nlmimage10 120e0910
Prenatal Plus IronTablet, film coatedOralMajor2011-06-07Not applicableUs
PreNatal Vitamins PlusTabletOralbryant ranch prepack2011-04-15Not applicableUs
Prenatal Vitamins Plus Low IronTabletOralPatrin Pharma2013-04-01Not applicableUs39328 0106 10 nlmimage10 df476fdb
Prenatal, DHAKitPure Tek Corporation2017-08-10Not applicableUs
Prenate EliteTablet, coatedOralAvion Pharmaceuticals, Llc2012-08-06Not applicableUs
PRENATE EnhanceCapsule, gelatin coatedOralAvion Pharmaceuticals, Llc2013-09-17Not applicableUs
Prenate EssentialCapsule, gelatin coatedOralAvion Pharmaceuticals, Llc2014-07-18Not applicableUs
Prenate PixieTablet, film coatedOralAvion Pharmaceuticals, Llc2014-08-14Not applicableUs
PRENATE RestoreCapsule, gelatin coatedOralAvion Pharmaceuticals, Llc2013-09-17Not applicableUs
Prenate StarTablet, coatedOralAvion Pharmaceuticals, Llc2014-06-05Not applicableUs
Prenavite ForteTabletOralAllen & Hanburys A Glaxo Canada Ltd. Co.1986-12-311996-09-10Canada
Prenavite Forte TabletsTabletOralRoberts Pharmaceutical1995-12-311999-08-11Canada
Prenavite TabletsTabletOralRoberts Pharmaceutical1995-12-311999-08-11Canada
PreNexaCapsule, gelatin coatedOralUpsher Smith Laboratories2010-05-25Not applicableUs
PrePLUSTabletOralVirtus Pharmaceuticals2014-04-04Not applicableUs
PreQue 10TabletOralActavis Pharma Company2011-11-01Not applicableUs
PreTABTabletOralVirtus Pharmaceuticals2014-04-092017-08-08Us
Prevital TabTabletOralBio Vita1991-12-312000-07-20Canada
Pro-aceTabletOralProfessional Health Products1998-08-261999-07-19Canada
Procosa IITabletOralUsana Health Sciences, Inc.2002-07-082008-06-27Canada
PureVit DualFe PlusCapsuleOralPure Tek Corporation2011-06-01Not applicableUs
Q.T. Vitamin and Mineral Drink MixPowderOralGarden State NutritionalsNot applicableNot applicableCanada
Reaphirm Plant Source DHACapsule, gelatin coatedOralEverett Laboratories, Inc.2011-12-05Not applicableUs
Redoxon-calTablet, effervescentOralBayer Inc Consumer Care1992-12-312007-08-02Canada
ReebokLiquidOralClearly Canadian Beverage Corporation2003-05-152009-08-06Canada
ReleaseCapsuleOralNew Vision Nutritionals Company1998-10-012002-11-20Canada
Reliv So Sense Daily Vitamin SupplementPowder, for solutionOralReliv International Inc.2000-03-242007-07-10Canada
Remedium - Liq OrlLiquidOralF.E.S. Trading Canada Ltd.1995-12-312007-09-25Canada
Reno CapsCapsuleOralNnodum Pharmaceuticals2008-11-30Not applicableUs63044 0622 01 nlmimage10 7d3cbea5
ReplaviteTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1999-10-202002-07-31Canada
Revit Plus CapCapsuleOralIcn Pharmaceuticals1972-12-311998-08-13Canada
Revit TabTabletOralIcn Pharmaceuticals1980-12-311998-08-13Canada
Revival 1 TabTabletOralBio Vita1991-12-311999-08-12Canada
Rhume Et De LA Grippe (extra-fort)Powder, for solutionOralProdemdis Enr.1993-12-302010-07-15Canada
Right Choice A.M. Multi Formula - CapletTabletOralBody Wise International LlcNot applicableNot applicableCanada
S.H. Drink MixPowderOralWatkins Incorporated1998-04-302005-08-23Canada
SamsonTabletOralScandinavian Formulas Inc.1997-04-012001-07-24Canada
Se-Care ChewableTablet, chewableOralSeton Pharmaceuticals2009-05-012016-10-13Us
Se-Natal 19TabletOralSeton Pharmaceuticals2009-07-01Not applicableUs
Se-Natal 19 ChewableTablet, chewableOralSeton Pharmaceuticals2009-07-01Not applicableUs
Se-Natal OneTabletOralSeton Pharmaceuticals2009-04-162016-10-13Us
Se-Tan DHACapsule, gelatin coatedOralSeton Pharmaceuticals2009-10-012016-04-30Us
Se-Tan PLUSCapsule, gelatin coatedOralSeton Pharmaceuticals2009-10-01Not applicableUs
Selenium PlusTabletOralFlora Manufacturing And Distributing Ltd.1985-12-311999-10-18Canada
Sincera - TabletsTabletOralScandinavian Formulas Inc.1997-04-082005-02-16Canada
Soin Solaire Complete SPF30EmulsionTopicalElemis Limited2012-03-27Not applicableUs
Somarexin and C 1000Liquid; TabletOralLaboratoire Lalco Inc.1977-12-312008-07-29Canada
Somavit Brand Vitamins and Minerals ComplexTabletOralSoma Health Products2000-01-152005-08-26Canada
Sopalamine/3b Plus CTabletOralTechnilab Pharma Inc.1987-12-312001-09-05Canada
Spd TabTabletOralSeroyal International Inc.1988-12-311996-09-10Canada
Spectra 301 Vitamin and Mineral SuppTabletOralNf Formulas Inc.1986-12-312000-07-05Canada
Spectrum 2 CapCapsuleOralNf Formulas Inc.1988-12-312008-06-26Canada
Stress B & C CapletTabletOralHealth Wise Nutrition Inc.1995-12-311998-08-25Canada
Stress B Capsules With Vitamin CCapsuleOralRheingold Food International Ltd.1987-12-312007-07-26Canada
Stress B Complex With C, E & IronTabletOralPharmavite1999-10-312005-07-15Canada
Stress B With 1000 Mg Vitamin CTabletOralHolista Health (Canada) Inc.2002-11-132008-07-17Canada
Stress B&c TabTabletOralBioforce Canada Inc.1985-12-311997-04-04Canada
Stress Complex 600 Avec Vit E Cuivre ZincTabletOralFrega Inc.1995-12-312008-02-13Canada
Stress Ctr SrtTablet, extended releaseOralBioenergy Inc.1979-12-311998-06-03Canada
Stress FormulaTabletOralVita Health Products Inc1998-05-202005-07-20Canada
Stress Formula + IronTabletOralVita Health Products Inc1998-05-202006-07-31Canada
Stress Formula B-comp + 500mg Vit C TabTabletOralQuest Vitamins A Div Of Purity Life Health Products1987-12-312002-07-29Canada
Stress Formula Multi-B Comp + 500mg Vit C CapCapsuleOralQuest Vitamins A Div Of Purity Life Health Products1987-12-312001-07-06Canada
Stress Formula Multivitamin Tablets USPTabletOralLeiner Health ProductsNot applicableNot applicableCanada
Stress Formula TabTabletOralNatures Sunshine Products, Inc.1986-12-312009-09-09Canada
Stress Formula Vit B With C ComplexTabletOralWatkins Incorporated1985-12-312000-01-15Canada
Stress Forte Plus Lipotropic FactorsTabletOralDouglas Laboratories1995-12-312009-09-29Canada
Stress TabTabletOralVita Health Products Inc1981-12-312005-07-20Canada
Stress TabletsTabletOralD.C. Labs Limited1981-12-312003-07-11Canada
Stress Vitamin B With C Complex TabletsTabletOralPurity Life Health Products A Division Of Sunopta Inc.2002-06-012007-07-26Canada
StressmatesTabletOralTwin Laboratories Inc.1995-12-311999-11-10Canada
Strovite Forte CapletTablet, coatedOralEverett Laboratories, Inc.1996-10-01Not applicableUs
Strovite One CapletsTabletOralEverett Laboratories, Inc.2001-05-04Not applicableUs
Sun-rype VitaburstLiquidOralSun Rype Products Ltd.2004-08-102008-03-13Canada
Super 7 Vitamin and Mineral SupplementCapsuleOralT & T Nutrition Inc.Not applicableNot applicableCanada
Super B Compound W 500mg Vit CTabletOralGahler Enterprises Ltd.1986-12-312000-08-01Canada
Super C Crystals W CalciumPowderOralNu Life Nutrition Ltd.1987-12-312005-03-15Canada
Super Charged EnergyPowderOralSimone Protective Pharmaceuticals, Inc.Not applicableNot applicableCanada
Super Daily No 2TabletOralW.R. Enterprises Inc.1990-12-312003-07-30Canada
Super PantoplexTabletOralNu Life Nutrition Ltd.1987-12-312000-03-03Canada
Super Stress CapsulesCapsuleOralRheingold Food International Ltd.1987-12-311997-08-22Canada
Super Stress Mega B Plus 1000mg Vit C TabTabletOralQuest Vitamins A Div Of Purity Life Health Products1987-12-312001-07-06Canada
Super-A Vitamins With Selenium Dietary SupplementTabletOralGarden State Nutritionals1998-09-222000-06-07Canada
Super-cellCapsuleOralBody Wise International LlcNot applicableNot applicableCanada
Super-pote Vitamin SupplementTabletOralGarden State Nutritionals1998-09-252000-06-07Canada
Supplement De Multivitamines Infusion Arome Fruits RougesKitOralYves Rocher Inc.1999-10-182000-08-08Canada
Supplement De Vitamines Et MinerauxLiquidOralLand Art Inc.1998-01-201999-08-02Canada
Supplements De Vitamines Et MinerauxLiquidOralLand Art Inc.1999-08-022008-06-26Canada
Supravite C 1000Liquid; TabletOralNobel Pharm Enr.1981-12-312002-09-06Canada
Supravite Pour EnfantsTabletOralPharmalab Inc.1985-12-312008-07-14Canada
Supravite Stress Avec Vit ETabletOralPharmalab Inc.1985-12-311997-08-08Canada
Supravite Stress Avec Vit E Cuivre Et ZincTabletOralPharmalab Inc.1985-12-311997-08-08Canada
Supravite Stress Avec Vit E Et FerTabletOralPharmalab Inc.1985-12-311997-08-08Canada
Surbex 500 FilmtabTabletOralAbbott1979-12-312008-06-06Canada
Surbex-500 With IronTabletOralAbbott1986-12-312008-06-06Canada
Surbex-500 With ZincTabletOralAbbott1986-12-312008-06-06Canada
SveetsLozengeOralSensible Delights Specialty Foods1998-09-162000-09-19Canada
Synergistic Manganese CapsulesCapsuleOralQuest Vitamins A Div Of Purity Life Health Products1996-08-151999-08-08Canada
Tandem DHACapsuleOralUs Pharmaceutical Corporation2007-01-17Not applicableUs
Tandem OBCapsuleOralUs Pharmaceutical Corporation2006-06-17Not applicableUs
Tandem PlusCapsuleOralUs Pharmaceutical Corporation2006-06-17Not applicableUs
Tar-endCapsuleOralNatures Sunshine Products, Inc.1999-05-252006-07-10Canada
Tender Age Multi VitaminsLiquidOralJamieson Laboratories Ltd1982-12-312000-09-08Canada
Tender Age Vit Adc DropsLiquidOralJamieson Laboratories Ltd1985-12-312000-09-08Canada
Theraplex AcpTabletOralTherapeutic Foods Co.1988-03-232004-07-22Canada
Thiamine HCl 100mg W C 20mgTabletOralGahler Enterprises Ltd.1987-12-312005-08-15Canada
Thymunase TabTabletOralAnabolic Laboratories Inc.1983-12-312004-03-15Canada
Timed Release and Esterified Vitamin C-500TabletOralGreat Earth Companies, Inc.1998-09-252002-10-02Canada
Timed Release Ester-C 1000mgTablet, extended releaseOralSwiss Herbal Remedies Ltd.1998-05-292008-08-15Canada
Tl-hem 150Tablet, film coatedOralTrigen Laboratories, Inc.2011-01-01Not applicableUs
Tonicol Et A-D-C Ampoules/comprimesLiquid; TabletOralDistributions Multi Pro Inc.1988-12-311999-07-21Canada
Tonimol Cap LiqCapsule; LiquidOralHerbes Universelles Inc.1978-12-312009-07-15Canada
Total FluPowder, for solutionOralPharmetics (2011) Inc.Not applicableNot applicableCanada
TozalCapsule, gelatin coatedOralFocus Laboratories, Inc.2013-06-012016-10-13Us
Tri AdrenopanCapsule, extended releaseOralAnabolic Laboratories Inc.1980-12-312004-03-15Canada
Tri Vi Flor TabTabletOralMead Johnson Nutritionals1992-12-311998-09-28Canada
Tri-VI-sol DropsLiquidOralMead Johnson Nutritionals1986-12-312000-09-11Canada
Tri-Vit With Fluoride And Iron DropsSolutionOralQualitest1997-11-17Not applicableUs
Tri-Vit with Fluoride DropsSolutionOralA S Medication Solutions1995-04-012017-06-20Us
Tri-Vitamin with FluorideSolution / dropsOralSancilio & Company Inc.2011-12-20Not applicableUs
TriAdvanceTabletOralTrigen Laboratories, Inc.2010-09-102017-09-16Us
Tricare PrenatalTablet, coatedOralMedecor Pharma, Llc2002-11-11Not applicableUs
TriconCapsuleOralNnodum Pharmaceuticals2005-05-20Not applicableUs
Trinatal GTTabletOralTrigen Laboratories, Inc.2011-07-052017-09-13Us
Triple Vitamin Drops with FluorideLiquidOralStratus Pharmaceuticals2014-09-01Not applicableUs
Triple-Vitamin Drops with FluorideSolution / dropsOralBoca Pharmacal, Inc.2011-06-142016-03-31Us
Triveen-PRx RNFCapsuleOralTrigen Laboratories, Inc.2010-05-152017-09-16Us
Tropicana Calcium & Vitamin C SupplementLiquidOralTropicana Canada2001-07-092002-09-06Canada
Tropicana Calcium and Vitamin C SupplementLiquidOralTropicana Canada1999-05-172002-09-06Canada
Twin Ultra Liquid Fruit Punch FlavorLiquidOralTwin Laboratories Inc.1995-12-312002-09-11Canada
Twin Ultra Liquid Grape FlavorLiquidOralTwin Laboratories Inc.1995-12-312007-08-01Canada
Twin Ultra Liquid Lemon-lime FlavorLiquidOralTwin Laboratories Inc.1995-12-312005-08-30Canada
Twin Ultra Liquid Orange FlavorLiquidOralTwin Laboratories Inc.1995-12-312002-09-11Canada
UltimateCare ONE NFCapsuleOralTrigen Laboratories, Inc.2009-12-042017-09-16Us
Ultra HrTabletOralNatural Organics Inc.Not applicableNot applicableCanada
Usana Megavitamin Tablets - TabTabletOralUsana Health Sciences, Inc.1996-12-302000-09-11Canada
Usana Procosa TabletsTabletOralUsana Health Sciences, Inc.1998-07-272002-07-22Canada
V-V Dietary SupplementTabletOralGarden State NutritionalsNot applicableNot applicableCanada
Vasodyn TabTabletOralNutri Dyn Products Ltd.1978-12-311998-08-13Canada
VemaVite-PRx 2 with Fish-Based DHACapsuleOralTrigen Laboratories, Inc.2011-10-05Not applicableUs
Vi-daylin Adc Vitamins Drops for InfantsLiquidOralAbbott1993-12-312007-07-31Canada
Viamon Ampoules Et ComprimesLiquid; TabletOralLab Nadeau LtÉe, Division Of Technilab Inc.1977-12-311999-09-28Canada
Vigo Multivitamins Drops/lozengeLozengeOralAshbury Research CorporationNot applicableNot applicableCanada
Vimeral TabTabletOralIcn Pharmaceuticals1979-12-312005-04-26Canada
Virt-CapsCapsule, gelatin coatedOralVirtus Pharmaceuticals2014-04-012017-08-11Us
Virt-PnTablet, coatedOralVirtus Pharmaceuticals2012-07-122017-08-09Us
Virt-Pn DHACapsule, gelatin coatedOralVirtus Pharmaceuticals2012-07-122017-08-08Us
Virt-PN PlusCapsule, gelatin coatedOralVirtus Pharmaceuticals2013-03-012017-08-08Us
Virt-Vite PlusTabletOralVirtus Pharmaceuticals2014-01-142017-08-11Us
Vit B Complex Plus Vit C 550mgCapsuleOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Vit C Chew Tab 250mgTabletOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Vit C Chew Tab 500mgTabletOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Vit C Tab 500mgTabletOralAlbi Naturals1982-12-312008-07-17Canada
Vit C W Calc-mag and Potass PowderPowder, for solutionOralNf Formulas Inc.1986-12-312000-07-05Canada
Vit-HA Multi Vitamin and Zinc SupplementTabletOralRheingold Food International Ltd.1994-12-312007-07-26Canada
Vita B + C 500 TabTabletOralLaboratoire Romilo1993-12-311999-08-18Canada
Vita Day TabTabletOralJamieson Laboratories Ltd1993-12-311997-08-13Canada
Vitachrom GcTabletOralNikken Usa, Incorporated2000-08-302007-10-01Canada
Vitaday TabTabletOralPharmetics (2011) Inc.1977-12-311999-08-13Canada
VitafantTabletOralLes Laboratoires Vachon Inc.1994-12-312008-07-09Canada
Vitaflex Dietary SuplementTabletOralHome Shopping Network DirectNot applicableNot applicableCanada
Vitafol CapletCapsuleOralEverett Laboratories, Inc.1985-05-01Not applicableUs
Vitafol OB CapletTabletOralExeltis Usa, Inc.2002-12-02Not applicableUs
Vitafol OneCapsule, gelatin coatedOralEverett Laboratories, Inc.2011-06-13Not applicableUs
Vitafol PlusCapsule, liquid filledOralEverett Laboratories, Inc.2012-04-23Not applicableUs
Vitafol UltraCapsule, liquid filledOralExeltis Usa, Inc.2013-09-23Not applicableUs
Vitalife - CapsuleCapsuleOralHolista Health (Canada) Inc.1996-11-132002-08-06Canada
VitalisCapsuleOralImport Export SantÉ Nature Inc.1999-02-202003-08-01Canada
Vitamin and Mineral Supplement CapsulesCapsuleOralVita Health Products Inc2004-01-052005-07-20Canada
Vitamin B + C CapCapsuleOralFinlandia Consultants1990-12-311997-12-02Canada
Vitamin B Complex + C 300mg CapCapsuleOralRandle Pharmaceutical Inc.1987-12-311997-05-30Canada
Vitamin B Complex + C 600mg TabTabletOralRandle Pharmaceutical Inc.1987-12-311997-05-30Canada
Vitamin B Complex Plus 300mg Vitamin CTabletOralHall Laboratories, Ltd.1996-11-282003-09-11Canada
Vitamin B Complex Plus C 300mg Timed ReleaseTablet, extended releaseOralVita Health Products Inc1998-10-062009-08-06Canada
Vitamin B Complex W C 300mg TabTabletOralLee Adams Laboratories1982-12-312009-12-02Canada
Vitamin B Complex W C TabTabletOralAlbi Imports Ltd.1979-12-312004-09-24Canada
Vitamin B Compound W C Tab 500mgTabletOralAdams Laboratories1979-12-312009-10-21Canada
Vitamin B Compound W Vit C 250mg TabTabletOralSwiss Herbal Remedies Ltd.1972-12-312003-09-10Canada
Vitamin B Compound With Vitamin C Fortis Capsule DtcCapsuleOralD.C. Labs Limited1973-12-312005-07-19Canada
Vitamin B Cpd W Vit C TabTabletOralIcn Pharmaceuticals1978-12-312005-04-26Canada
Vitamin C Chew Sug Fr 500mgTabletOralWampole Brands, A Division Of Pangeo Pharma (Canada) Inc.1991-12-311996-09-09Canada
Vitamin C & Zinc TabTabletOralPep Products Inc.1991-12-311999-10-29Canada
Vitamin C + Zinc TabTabletOralHillestad Pharmaceuticals Usa1989-12-312009-09-22Canada
Vitamin C 250mg ChewableTabletOralAlbi Naturals1982-12-312008-07-17Canada
Vitamin C 500 Tab ChewableTabletOralKripps Pharmacy Ltd.1979-12-311997-08-01Canada
Vitamin C and Calcium TabTabletOralNatrol, Inc.1997-09-011999-08-10Canada
Vitamin C and Zinc LozengesLozengeOralRx Vitamins Inc.1998-09-252007-10-25Canada
Vitamin C Calcium PwrPowderOralSisu Inc.1987-12-312005-07-13Canada
Vitamin C Tab 1000mgTabletOralVita Health Products Inc1985-12-312005-07-20Canada
Vitamin C Tab 1000mg ChewableTabletOralAlbi Naturals1984-12-312008-07-17Canada
Vitamin C Tab 100mgTabletOralAlbi Naturals1979-12-312008-07-17Canada
Vitamin C Tab 100mg ChewableTabletOralPharmetics (2011) Inc.1973-12-312001-07-26Canada
Vitamin C Tab 100mg Chewable OrangeTabletOralShoppers Drug Mart Inc.1977-12-311997-08-15Canada
Vitamin C Tab 250mg ChewableTabletOralWampole Brands1973-12-312009-06-19Canada
Vitamin C Tab 250mg Chewable OrangeTabletOralShoppers Drug Mart Inc.1982-12-311997-08-15Canada
Vitamin C Tab 500mgTabletOralNobel Pharm Enr.1983-12-312001-10-15Canada
Vitamin C Tab 500mg ChewableTabletOralPharmetics (2011) Inc.1973-12-312005-08-04Canada
Vitamin C Tab 500mg Chewable OrangeTabletOralShoppers Drug Mart Inc.1977-12-311998-08-14Canada
Vitamin C Tab 500mg Orange FlavorTabletOralVita Health Products Inc1982-12-311996-09-09Canada
Vitamin C Tab 500mg Orange Flavoured ChewableTabletOralVita Health Products Inc1972-12-312004-07-26Canada
Vitamin C Tablets Chewable 250mgTabletOralD.C. Labs Limited1973-12-312003-07-11Canada
Vitamin C Tablets Chewable 500mgTabletOralD.C. Labs Limited1973-12-312003-07-11Canada
Vitamin E + 3 (extra Strength)TabletOralWn Pharmaceuticals Ltd.1999-01-212001-08-03Canada
Vitamin E + 3 Extra Strength With ZincTabletOralWn Pharmaceuticals Ltd.2000-12-012009-09-28Canada
Vitamine C 100mg 5 Fruits-tabTabletOralLaboratoire Lalco Inc.1996-12-312002-09-05Canada
Vitamine C 100mg Tab MasticableTabletOralBio Vita1987-12-311997-08-07Canada
Vitamine C 250mg Tab MasticableTabletOralBio Vita1987-12-312004-07-22Canada
Vitamine C 500mg 5-fruits - TabTabletOralNobel Pharm Enr.1995-12-312001-10-15Canada
Vitamine C 500mg 5-fruits TabTabletOralLaboratoire Lalco Inc.1993-12-312006-09-07Canada
Vitamine C Croquable Tab 500mgTabletOralLes Produits Naturels Suisse Inc.1993-12-311996-09-09Canada
Vitamine C Tab 100mgTabletOralLab Gernetic Int Ltee1985-12-311997-02-21Canada
Vitamine C Tab 250mgTabletOralDistributions Multi Pro Inc.1984-12-312008-11-19Canada
Vitamines Pour Bebes Et EnfantsLiquidOralHerbes Universelles Inc.1978-12-312009-07-15Canada
VITAMINS A, C, D and FLUORIDESolution / dropsOralMayne Pharma2011-05-212019-10-31Us
Vitogen B Compound W C Fortis CapsulesCapsuleOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1972-12-311997-10-14Canada
Vitogen B Stress C Vit E Zinc & CopTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1984-12-312002-07-31Canada
Vitogen B Stress C600TabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1981-12-312002-07-31Canada
Vitogen Multiple Vitamins TabTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1966-12-311997-10-14Canada
Vitogen Multiple Vitamins W IronTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1976-12-311997-10-14Canada
Vitreat Chewable Vitamin TabTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1972-12-311997-08-08Canada
Vitreat Chewable Vitamins Plus IronTabletOralStanley Pharmaceuticals, A Division Of Vita Health Products Inc.1977-12-311997-08-08Canada
VP-HEME OneCapsule, gelatin coatedOralVirtus Pharmaceuticals2013-03-01Not applicableUs
Vtb Vitamin and Mineral SupplementTabletOralGarden State NutritionalsNot applicableNot applicableCanada
Women's FormulaTabletOralPro Ma Systems1998-10-312007-09-25Canada
Women's Support TabletsTabletOralGeneral Nutrition Canada Inc.1997-09-122005-08-05Canada
Z-force Vitamin and Mineral SupplementCapsuleOralDymatize Enterprises Inc.2001-12-122006-10-06Canada
Zinc 50mg W Vitamin CTabletOralFoodscience Laboratories, Division Of Foodscience Corporation1986-12-311997-05-08Canada
Zinc and Vitamin C LozengesLozengeOralHealth Wise Nutrition Inc.1997-08-152000-07-29Canada
Zinc Lozenge With Vitamin CTabletOralWn Pharmaceuticals Ltd.1998-05-202000-01-06Canada
Zinc Lozenges With Vitamin CLozengeOralAshbury Research CorporationNot applicableNot applicableCanada
Zinc Lozenges With Vitamin C and Non-medicinal EchinaceaLozengeOralVita Health Products Inc1999-05-212002-07-31Canada
Zinc Lozenges With Vitamin C In A Nonmedicinal Base With Echinacea LozengeLozengeOralPurity Life Health Products A Division Of Sunopta Inc.2002-06-012007-07-26Canada
Zinc Plus Extra CLozengeOralAmerifit Inc.Not applicableNot applicableCanada
Zinc Plus LozengesLozengeOralSwiss Herbal Remedies Ltd.1998-05-292009-08-04Canada
Zinc Plus Vitamins C & B6 LozengesLozengeOralVita Plus Industries Inc.Not applicableNot applicableCanada
Zinc With C - LozLozengeOralMetagenics, Inc.1997-02-012005-08-19Canada
Zinc With C LozengeLozengeOralNatures Sunshine Products, Inc.1998-01-262000-07-14Canada
Zinc With Vitamin C LozengesTabletOralPrairie Naturals2002-01-152004-10-07Canada
Zinc-C LozengesLozengeOralTwin Laboratories Inc.1995-12-311999-11-10Canada
Zinc-C-lozengesLozengeOralRheingold Food International Ltd.1994-12-312007-07-26Canada
Zoo ChewsTabletOralHall Laboratories, Ltd.1981-12-312003-09-11Canada
Zymain TabTabletOralAnabolic Laboratories Inc.1985-12-312004-03-15Canada
Categories
UNII
PQ6CK8PD0R
CAS number
50-81-7
Weight
Average: 176.1241
Monoisotopic: 176.032087988
Chemical Formula
C6H8O6
InChI Key
CIWBSHSKHKDKBQ-JLAZNSOCSA-N
InChI
InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
IUPAC Name
(5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2,5-dihydrofuran-2-one
SMILES
[H][[email protected]@]1(OC(=O)C(O)=C1O)[[email protected]@H](O)CO

Pharmacology

Indication

Used to treat vitamin C deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. It has also been suggested to be an effective antiviral agent.

Structured Indications
Not Available
Pharmacodynamics

Ascorbic Acid (vitamin C) is a water-soluble vitamin indicated for the prevention and treatment of scurvy, as ascorbic acid deficiency results in scurvy. Collagenous structures are primarily affected, and lesions develop in bones and blood vessels. Administration of ascorbic acid completely reverses the symptoms of ascorbic acid deficiency.

Mechanism of action

In humans, an exogenous source of ascorbic acid is required for collagen formation and tissue repair by acting as a cofactor in the posttranslational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. Ascorbic acid is reversibly oxidized to dehydroascorbic acid in the body. These two forms of the vitamin are believed to be important in oxidation-reduction reactions. The vitamin is involved in tyrosine metabolism, conversion of folic acid to folinic acid, carbohydrate metabolism, synthesis of lipids and proteins, iron metabolism, resistance to infections, and cellular respiration.

TargetActionsOrganism
UProlyl 4-hydroxylase subunit alpha-1Not AvailableHuman
USolute carrier family 23 member 1Not AvailableHuman
UProcollagen-lysine,2-oxoglutarate 5-dioxygenase 1
activator
Human
UHyaluronate lyaseNot AvailableStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
UDNANot AvailableHuman
UXylose isomeraseNot AvailableStreptomyces rubiginosus
UProcollagen-lysine,2-oxoglutarate 5-dioxygenase 2Not AvailableHuman
UPhytanoyl-CoA dioxygenase, peroxisomalNot AvailableHuman
UProcollagen-lysine,2-oxoglutarate 5-dioxygenase 3Not AvailableHuman
UGamma-butyrobetaine dioxygenaseNot AvailableHuman
UDopamine beta-hydroxylaseNot AvailableHuman
UPeptidyl-glycine alpha-amidating monooxygenaseNot AvailableHuman
UProlyl 3-hydroxylase 1Not AvailableHuman
U2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2Not AvailableHuman
UAlpha-ketoglutarate-dependent dioxygenase alkB homolog 2Not AvailableHuman
UProlyl 3-hydroxylase 2Not AvailableHuman
UProlyl 3-hydroxylase 3Not AvailableHuman
U2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1Not AvailableHuman
UEgl nine homolog 2Not AvailableHuman
UAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3Not AvailableHuman
ULysine-specific demethylase 5DNot AvailableHuman
UEgl nine homolog 1Not AvailableHuman
UEgl nine homolog 3Not AvailableHuman
UTrimethyllysine dioxygenase, mitochondrialNot AvailableHuman
UTransmembrane prolyl 4-hydroxylaseNot AvailableHuman
ULactase-phlorizin hydrolaseNot AvailableHuman
Absorption

70% to 90%

Volume of distribution
Not Available
Protein binding

25%

Metabolism

Hepatic. Ascorbic acid is reversibly oxidised (by removal of the hydrogen from the enediol group of ascorbic acid) to dehydroascorbic acid. The two forms found in body fluids are physiologically active. Some ascorbic acid is metabolized to inactive compounds including ascorbic acid-2-sulfate and oxalic acid.

Route of elimination
Not Available
Half life

16 days (3.4 hours in people who have excess levels of vitamin C)

Clearance
Not Available
Toxicity
Not Available
Affected organisms
  • Humans and other mammals
Pathways
PathwayCategory
Catecholamine BiosynthesisMetabolic
The oncogenic action of FumarateDisease
Oxidation of Branched Chain Fatty AcidsMetabolic
Aromatic L-Aminoacid Decarboxylase DeficiencyDisease
The oncogenic action of SuccinateDisease
Tyrosine MetabolismMetabolic
Refsum DiseaseDisease
Tyrosinemia, transient, of the newbornDisease
Tyrosinemia Type IDisease
Disulfiram Action PathwayDrug action
Carnitine SynthesisMetabolic
Tyrosine hydroxylase deficiencyDisease
AlkaptonuriaDisease
HawkinsinuriaDisease
Phytanic Acid Peroxisomal OxidationMetabolic
Dopamine beta-hydroxylase deficiencyDisease
Monoamine oxidase-a deficiency (MAO-A)Disease
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteractionDrug group
2,5-Dimethoxy-4-ethylamphetamineThe serum concentration of 2,5-Dimethoxy-4-ethylamphetamine can be decreased when it is combined with Vitamin C.Experimental, Illicit
3,4-MethylenedioxyamphetamineThe serum concentration of 3,4-Methylenedioxyamphetamine can be decreased when it is combined with Vitamin C.Experimental, Illicit
3,4-MethylenedioxymethamphetamineThe serum concentration of 3,4-Methylenedioxymethamphetamine can be decreased when it is combined with Vitamin C.Experimental, Illicit
4-Bromo-2,5-dimethoxyamphetamineThe serum concentration of 4-Bromo-2,5-dimethoxyamphetamine can be decreased when it is combined with Vitamin C.Experimental, Illicit
Aluminum hydroxideVitamin C can cause an increase in the absorption of Aluminum hydroxide resulting in an increased serum concentration and potentially a worsening of adverse effects.Approved
AmphetamineThe serum concentration of Amphetamine can be decreased when it is combined with Vitamin C.Approved, Illicit
BazedoxifeneThe serum concentration of Bazedoxifene can be increased when it is combined with Vitamin C.Approved, Investigational
BenzphetamineThe serum concentration of Benzphetamine can be decreased when it is combined with Vitamin C.Approved, Illicit
BortezomibThe therapeutic efficacy of Bortezomib can be decreased when used in combination with Vitamin C.Approved, Investigational
ChlorotrianiseneThe serum concentration of Chlorotrianisene can be increased when it is combined with Vitamin C.Withdrawn
ChlorphentermineThe serum concentration of Chlorphentermine can be decreased when it is combined with Vitamin C.Illicit, Withdrawn
Conjugated estrogensThe serum concentration of Conjugated Equine Estrogens can be increased when it is combined with Vitamin C.Approved
CopperThe serum concentration of Vitamin C can be decreased when it is combined with Copper.Approved
CyclosporineThe serum concentration of Cyclosporine can be decreased when it is combined with Vitamin C.Approved, Investigational, Vet Approved
DeferoxamineThe risk or severity of adverse effects can be increased when Vitamin C is combined with Deferoxamine.Approved, Investigational
DextroamphetamineThe serum concentration of Dextroamphetamine can be decreased when it is combined with Vitamin C.Approved, Illicit
DienestrolThe serum concentration of Dienestrol can be increased when it is combined with Vitamin C.Approved
DiethylpropionThe serum concentration of Diethylpropion can be decreased when it is combined with Vitamin C.Approved, Illicit
DiethylstilbestrolThe serum concentration of Diethylstilbestrol can be increased when it is combined with Vitamin C.Approved
EquolThe serum concentration of S Equol can be increased when it is combined with Vitamin C.Investigational
EstradiolThe serum concentration of Estradiol can be increased when it is combined with Vitamin C.Approved, Investigational, Vet Approved
EstriolThe serum concentration of Estriol can be increased when it is combined with Vitamin C.Approved, Vet Approved
EstroneThe serum concentration of Estrone can be increased when it is combined with Vitamin C.Approved
Ethinyl EstradiolThe serum concentration of Ethinyl Estradiol can be increased when it is combined with Vitamin C.Approved
GenisteinThe serum concentration of Genistein can be increased when it is combined with Vitamin C.Investigational
HexestrolThe serum concentration of Hexestrol can be increased when it is combined with Vitamin C.Withdrawn
HydroxyamphetamineThe serum concentration of Hydroxyamphetamine hydrobromide can be decreased when it is combined with Vitamin C.Approved
LisdexamfetamineThe serum concentration of Lisdexamfetamine can be decreased when it is combined with Vitamin C.Approved, Investigational
MephedroneThe serum concentration of Mephedrone can be decreased when it is combined with Vitamin C.Investigational
MephentermineThe serum concentration of Mephentermine can be decreased when it is combined with Vitamin C.Approved
MestranolThe serum concentration of Mestranol can be increased when it is combined with Vitamin C.Approved
MethallenestrilThe serum concentration of Methallenestril can be increased when it is combined with Vitamin C.Experimental
MethamphetamineThe serum concentration of Methamphetamine can be decreased when it is combined with Vitamin C.Approved, Illicit
MMDAThe serum concentration of MMDA can be decreased when it is combined with Vitamin C.Experimental, Illicit
PhentermineThe serum concentration of Phentermine can be decreased when it is combined with Vitamin C.Approved, Illicit
Polyestradiol phosphateThe serum concentration of Polyestradiol phosphate can be increased when it is combined with Vitamin C.Approved
PromestrieneThe serum concentration of Promestriene can be increased when it is combined with Vitamin C.Investigational
PseudoephedrineThe serum concentration of Pseudoephedrine can be decreased when it is combined with Vitamin C.Approved
QuinestrolThe serum concentration of Quinestrol can be increased when it is combined with Vitamin C.Approved
RitobegronThe serum concentration of Ritobegron can be decreased when it is combined with Vitamin C.Investigational
SecoisolariciresinolThe serum concentration of Secoisolariciresinol can be increased when it is combined with Vitamin C.Investigational
Synthetic Conjugated Estrogens, AThe serum concentration of Synthetic Conjugated Estrogens, A can be increased when it is combined with Vitamin C.Approved
Synthetic Conjugated Estrogens, BThe serum concentration of Synthetic Conjugated Estrogens, B can be increased when it is combined with Vitamin C.Approved
TiboloneThe serum concentration of Tibolone can be increased when it is combined with Vitamin C.Approved
ZeranolThe serum concentration of Zeranol can be increased when it is combined with Vitamin C.Vet Approved
Food Interactions
Not Available

References

Synthesis Reference

Lewis D. Morse, Paul A. Hammes, "Beverage containing stabilized vitamin C and iron and method of making same." U.S. Patent US3958017, issued October, 1972.

US3958017
General References
  1. Padayatty SJ, Katz A, Wang Y, Eck P, Kwon O, Lee JH, Chen S, Corpe C, Dutta A, Dutta SK, Levine M: Vitamin C as an antioxidant: evaluation of its role in disease prevention. J Am Coll Nutr. 2003 Feb;22(1):18-35. [PubMed:12569111 ]
  2. Meister A: Glutathione-ascorbic acid antioxidant system in animals. J Biol Chem. 1994 Apr 1;269(13):9397-400. [PubMed:8144521 ]
  3. Englard S, Seifter S: The biochemical functions of ascorbic acid. Annu Rev Nutr. 1986;6:365-406. [PubMed:3015170 ]
  4. Banhegyi G, Mandl J: The hepatic glycogenoreticular system. Pathol Oncol Res. 2001;7(2):107-10. [PubMed:11458272 ]
  5. Proctor P: Similar functions of uric acid and ascorbate in man? Nature. 1970 Nov 28;228(5274):868. [PubMed:5477017 ]
  6. Korcok J, Dixon SJ, Lo TC, Wilson JX: Differential effects of glucose on dehydroascorbic acid transport and intracellular ascorbate accumulation in astrocytes and skeletal myocytes. Brain Res. 2003 Dec 12;993(1-2):201-7. [PubMed:14642847 ]
External Links
Human Metabolome Database
HMDB00044
KEGG Drug
D00018
KEGG Compound
C00072
PubChem Compound
54670067
PubChem Substance
46505070
ChemSpider
10189562
BindingDB
50090256
ChEBI
29073
ChEMBL
CHEMBL196
Therapeutic Targets Database
DNC000259
PharmGKB
PA451898
HET
ASC
RxList
RxList Drug Page
Drugs.com
Drugs.com Drug Page
PDRhealth
PDRhealth Drug Page
Wikipedia
Vitamin_C
ATC Codes
A11GB01 — Ascorbic acid (vit c) and calciumA11GA01 — Ascorbic acid (vit c)S01XA15 — Ascorbic acidG01AD03 — Ascorbic acid
AHFS Codes
  • 88:04.00
  • 88:12.00
PDB Entries
FDA label
Not Available
MSDS
Download (74.6 KB)

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
0CompletedDiagnosticPostural Tachycardia Syndrome1
0Not Yet RecruitingPreventionPrimary Postpartum Haemorrhage1
0RecruitingBasic ScienceHealthy Volunteers1
0Unknown StatusPreventionContrast Induced Nephropathy (CIN)1
1Active Not RecruitingTreatmentGBM / Glioblastoma Multiforme / Glioblastomas1
1Active Not RecruitingTreatmentNeoplasms, Pancreatic1
1CompletedNot AvailableHuman Immunodeficiency Virus (HIV) Infections / Infection, Human Immunodeficiency Virus I / Mycobacterium avium complex infection1
1CompletedDiagnosticHealthy Volunteers1
1CompletedPreventionHIV/AIDS1
1CompletedTreatmentAge Related Macular Degeneration (ARMD) / Neovascular Maculopathy1
1CompletedTreatmentCancers1
1CompletedTreatmentCancers / Metastases1
1CompletedTreatmentColorectal Cancers1
1CompletedTreatmentGastric Emptying / Healthy Volunteers1
1CompletedTreatmentMalignant Neoplasm of Pancreas1
1CompletedTreatmentNeoplasms, Pancreatic1
1CompletedTreatmentPharmacokinetics1
1CompletedTreatmentSafety and Pharmacokinetics of Intravenous Ascorbate1
1CompletedTreatmentVitamin C Deficiency1
1Not Yet RecruitingBasic ScienceAging / Mineral deficiency / Vitamin Deficiency1
1Not Yet RecruitingBasic ScienceArterial hypoxia / Hypercapnia1
1RecruitingBasic ScienceChronic Obstructive Pulmonary Disease (COPD) / Heart Failure, Unspecified / Hypertensive / Pulmonary Arterial Hypertension (PAH)1
1RecruitingBasic ScienceComplications Due to Coronary Artery Bypass Graft / Disorder of Vitamin C / Heart Valve Disease / Nonvalvular Atrial Fibrillation1
1RecruitingBasic ScienceCoronary Artery Bypass Graft Surgery1
1TerminatedTreatmentMetastatic Adenocarcinoma of the Pancreas1
1, 2CompletedTreatmentAcute Lung Injury (ALI) / Arterial Hypotension / Sepsis / Shock, Septic1
1, 2CompletedTreatmentAdvanced Liver Cancer / Metastatic Hepatocellular Carcinoma1
1, 2CompletedTreatmentAutism Spectrum Disorder (ASD) / Gastrointestinal Problems1
1, 2CompletedTreatmentCancer, Ovarian1
1, 2CompletedTreatmentMultiple Myeloma (MM) / Transplantation, Stem Cell1
1, 2CompletedTreatmentPlasma Cell Myeloma1
1, 2CompletedTreatmentTemporomandibular Joint Disorders1
1, 2Not Yet RecruitingTreatmentVitamin C Deficiency1
1, 2RecruitingTreatmentNon-Small-Cell Lung Carcinoma (NSCLC) / Recurrent Non-small Cell Lung Cancer / Stage IIIA Non-Small Cell Lung Cancer / Stage IIIB Non-Small Cell Lung Cancer / Stage IV Non-Small Cell Lung Cancer1
1, 2RecruitingTreatmentPostpartum Anemia1
1, 2SuspendedTreatmentSchizoaffective Disorders / Schizophrenic Disorders1
1, 2TerminatedTreatmentStage IV Colorectal Cancer1
2CompletedNot AvailableOccluded Totally Implanted Central Venous Catheter1
2CompletedPreventionCardiovascular Disease (CVD) / Coronary Arteriosclerosis / Coronary Heart Disease (CHD) / Heart Diseases / Myocardial Infarction (MI) / Myocardial Ischemia1
2CompletedPreventionHuman Immunodeficiency Virus (HIV) Infections1
2CompletedPreventionPreEclampsia1
2CompletedSupportive CareOral Mucositis1
2CompletedTreatmentCancer, Breast1
2CompletedTreatmentCancer, Ovarian / Cervical Cancers / Uterine Cancers1
2CompletedTreatmentCentral Serous Chorioretinopathy (CSC)1
2CompletedTreatmentColonoscopy1
2CompletedTreatmentHereditary areflexic dystasia / Hereditary Motor and Sensory Neuropathies1
2CompletedTreatmentMalignant Neoplasm of Colon1
2CompletedTreatmentMyelodysplastic Syndrome1
2CompletedTreatmentNon-Proliferative Diabetic Retinopathy / Type 2 Diabetes Mellitus1
2CompletedTreatmentPneumonia With Hospitalized Elderly Patient1
2CompletedTreatmentProstatic Neoplasms1
2CompletedTreatmentStage IV Pancreatic Cancer1
2Not Yet RecruitingSupportive CareTiredness1
2Not Yet RecruitingTreatmentAdenocarcinomas / Cancer of Pancreas / Cancer of the Pancreas / Malignant Neoplasm of Pancreas / Neoplasms, Pancreatic / Pancreas Neoplasms1
2Not Yet RecruitingTreatmentAtrial Fibrillation Ablation1
2Not Yet RecruitingTreatmentNon-Small-Cell Lung Carcinoma (NSCLC) / Nonsmall Cell Lung Cancer1
2Not Yet RecruitingTreatmentSevere Thermal Injury, Greater Than 20% TBSA1
2RecruitingNot AvailableBowel preparation therapy1
2RecruitingTreatmentAcute Lung Injury (ALI) / Sepsis1
2RecruitingTreatmentArteriovenous fistula occlusion1
2RecruitingTreatmentColorectal Cancers / Lung Cancers / Malignant Neoplasm of Pancreas1
2RecruitingTreatmentDelayed Onset Muscle Soreness, DOMS1
2RecruitingTreatmentDepressive State1
2RecruitingTreatmentDiabetes Mellitus Type 2 With Hyperglycemia / Periodontitis1
2RecruitingTreatmentGlioblastoma Multiforme1
2RecruitingTreatmentHuman Immunodeficiency Virus (HIV) Infections1
2RecruitingTreatmentNon-Small-Cell Lung Carcinoma (NSCLC)1
2RecruitingTreatmentSepsis1
2SuspendedTreatmentAcute Myeloid Leukaemias (AML) / Myelodysplastic Syndrome1
2SuspendedTreatmentAdenocarcinomas / Carcinoma NOS / Desmoplastic Small Round Cell Tumor (DSRCT) / Multiple Myeloma (MM) / Sarcomas1
2TerminatedPreventionAtherosclerosis / Cardiovascular Disease (CVD) / Carotid Artery Diseases / Cerebrovascular Disorders / Heart Diseases / Intracranial Arteriosclerosis / Vascular Diseases1
2TerminatedPreventionShock1
2TerminatedTreatmentAcute Myelogenous Leukaemia (AML)1
2TerminatedTreatmentNon-Hodgkin's Lymphoma (NHL)1
2Unknown StatusTreatmentSevere Sepsis1
2WithdrawnTreatmentRefractory Plasma Cell Neoplasm / Stage I Multiple Myeloma / Stage II Multiple Myeloma / Stage III Multiple Myeloma1
2WithdrawnTreatmentRefractory Plasma Cell Neoplasm / Stage II Multiple Myeloma / Stage III Multiple Myeloma1
2, 3CompletedPreventionElevated Blood Lead Levels1
2, 3CompletedTreatmentCardiovascular Disease (CVD) / Chronic Kidney Disease (CKD) / Mortality1
2, 3CompletedTreatmentCharcot-Marie-Tooth Disease, Type Ia1
2, 3CompletedTreatmentKidney Failure,Chronic / Restless Legs Syndrome (RLS)1
2, 3RecruitingPreventionOral Mucositis1
2, 3Unknown StatusTreatmentIron Chelation / Thalassemia Major (TM) / Vitamin c1
3CompletedPreventionAtrial Flutter / Nonvalvular Atrial Fibrillation1
3CompletedPreventionCardiovascular Disease (CVD) / Coronary Arteriosclerosis / Coronary Heart Disease (CHD) / Heart Diseases / Myocardial Ischemia / One to five years postmenopausal1
3CompletedPreventionComplications, Pregnancy / Human Immunodeficiency Virus (HIV) Infections1
3CompletedPreventionEclampsia / HELLP Syndrome / PreEclampsia / Pregnancy1
3CompletedPreventionAcute Rhinitis / Gastroenteritis1
3CompletedPreventionNonvalvular Atrial Fibrillation1
3CompletedSupportive CareColonic Diseases / Diabetes Mellitus (DM)1
3CompletedTreatmentAnemias1
3CompletedTreatmentArterial Occlusive Diseases / Cardiovascular Disease (CVD) / Diabetes Mellitus (DM) / Heart Diseases / Vascular Diseases1
3CompletedTreatmentBowel Preparation Prior to Endoscopic, Radiological and Other Examinations as Well as to Surgical Procedures Which Require Empty Bowel1
3CompletedTreatmentColon Diseases / Colonoscopy Preparation1
3CompletedTreatmentColonoscopy3
3CompletedTreatmentDiarrheal Illnesses / Growth Faltering / Respiratory Illness1
3CompletedTreatmentHuman Immunodeficiency Virus (HIV) Infections / Tuberculosis, Pulmonary1
3Not Yet RecruitingTreatmentNeoplasms, Colorectal1
3RecruitingPreventionComplex Regional Pain Syndrome (CRPS) TYPE I1
3RecruitingTreatmentMalignant Neoplasm of Stomach1
3TerminatedPreventionMetabolic Diseases / Oxidative Stress1
3Unknown StatusNot AvailableAnemias / Low Birth Weight / Neonatal Mortality1
3Unknown StatusPreventionCataracts / Macular Degeneration1
3Unknown StatusPreventionDrug Safety1
3Unknown StatusTreatmentAlzheimer's Disease (AD) / Down Syndrome (DS)1
3Unknown StatusTreatmentUterine Leiomyomas1
3WithdrawnPreventionNonvalvular Atrial Fibrillation1
3WithdrawnTreatmentRespiratory Tract Infections (RTI)2
4Active Not RecruitingPreventionAspirin / Coronary Artery Disease1
4Active Not RecruitingTreatmentPostoperative pain1
4CompletedNot AvailableColonoscopy1
4CompletedNot AvailableAcute Rhinitis / Flu caused by Influenza1
4CompletedBasic ScienceFunctional Constipation / Irritable Bowel Syndrome Characterized by Constipation1
4CompletedPreventionAlgodystrophy / CRPS Type I / RSD (Reflex Sympathetic Dystrophy)1
4CompletedPreventionGestational Diabetes Mellitus (GDM)1
4CompletedPreventionInflammatory Reaction / Surgery, Cardiac1
4CompletedPreventionRenal Failure1
4CompletedPreventionReperfusion Injury1
4CompletedScreeningColorectal Cancers1
4CompletedTreatmentAcute Schizophrenia1
4CompletedTreatmentAnemias1
4CompletedTreatmentBowel Preparation for Colonoscopy1
4CompletedTreatmentChronic Alcoholic Hepatitis / Chronic Hepatitis C Virus (HCV) Infection / Hepatitis, Chronic1
4CompletedTreatmentColonoscopy1
4CompletedTreatmentColorectal Cleansing Prior Operation1
4CompletedTreatmentGallbladder Inflammation1
4CompletedTreatmentGastrointestinal Diseases1
4CompletedTreatmentGingival Hyperpigmentaion1
4CompletedTreatmentHyperemesis Gravidarum / Morning Sickness / Nausea / Pregnancy / Vomiting1
4CompletedTreatmentInflammatory Reaction / Uremia1
4CompletedTreatmentMultiple Organ Failure / Sepsis / Systemic Inflammatory Response Syndrome (SIRS) / Traumas1
4CompletedTreatmentPregnancy1
4Not Yet RecruitingTreatmentAge Related Macular Degeneration (ARMD) / Diabetic Macular Edema (DME) / Macular Edema (ME) / Retinal Vein Occlusions(RVO)2
4RecruitingSupportive CareRotator Cuff Syndrome1
4RecruitingTreatmentAnaemia Response to the Treatment / Oxalemia / Peripheral Iron Indices1
4RecruitingTreatmentAngina Pectoris1
4RecruitingTreatmentCardiovascular Disease (CVD) / Chronic Kidney Disease (CKD)1
4RecruitingTreatmentHuman Immunodeficiency Virus (HIV) Infections1
4RecruitingTreatmentIron-Deficiency Anemias1
4TerminatedPreventionSpinal Cord Injuries (SCI) / Urinary Tract Infections (UTIs)1
4TerminatedTreatmentAnemias1
4Unknown StatusTreatmentChronic Fatigue1
4Unknown StatusTreatmentLaparoscopic Nissen Fundoplication1
4WithdrawnTreatmentNephritis / Proteinuria / Systemic Lupus Erythematosus (SLE)1
Not AvailableActive Not RecruitingNot AvailableOxidative Stress / Type 2 Diabetes Mellitus1
Not AvailableActive Not RecruitingOtherOxidative Stress / Polytrauma1
Not AvailableCompletedNot AvailableHeart Failure, Unspecified1
Not AvailableCompletedNot AvailableHuman Immunodeficiency Virus (HIV) Infections1
Not AvailableCompletedNot AvailableHyponatremias1
Not AvailableCompletedBasic ScienceHyperglycemias1
Not AvailableCompletedHealth Services ResearchType 2 Diabetes Mellitus1
Not AvailableCompletedPreventionHealthy Volunteers1
Not AvailableCompletedPreventionNeural Tube Defects (NTDs)1
Not AvailableCompletedScreeningGlaucoma1
Not AvailableCompletedScreeningUlcerative Colitis (UC)1
Not AvailableCompletedTreatmentFusion of Spine (Disease)1
Not AvailableCompletedTreatmentHuman Immunodeficiency Virus (HIV) Infections1
Not AvailableCompletedTreatmentHypoxic Ischemic Encephalopathy (HIE) / Perinatal Asphyxia1
Not AvailableCompletedTreatmentPalatally Impacted Canines1
Not AvailableCompletedTreatmentModerate, refractory Atopic dermatitis1
Not AvailableEnrolling by InvitationTreatmentCholecystitis, Acute1
Not AvailableEnrolling by InvitationTreatmentDistal Radius Fractures / Finger Stiffness1
Not AvailableEnrolling by InvitationTreatmentGlucocorticoids Deficiency1
Not AvailableNot Yet RecruitingTreatmentBreast Cancer Metastatic / Metastatic Breast Cancer (MBC)1
Not AvailableRecruitingNot AvailableAcute Disease / Chronic Diseases / Vitamin C Deficiency1
Not AvailableRecruitingDiagnosticColonoscopy1
Not AvailableRecruitingTreatmentChronic Calculous Cholecystitis / Gallstone formation1
Not AvailableUnknown StatusDiagnosticPeripheral Arterial Disease (PAD)1
Not AvailableUnknown StatusSupportive CareCABG-Induced Oxidative Stress1
Not AvailableUnknown StatusTreatmentKidney Failure,Chronic1
Not AvailableWithdrawnPreventionHuman Immunodeficiency Virus (HIV) Infections1
Not AvailableWithdrawnScreeningPatients Undergoing Screening or Surveillance Colonoscopy1
Not AvailableWithdrawnTreatmentHuman Immunodeficiency Virus (HIV) Infections1
Not AvailableWithdrawnTreatmentMinor burns1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Dosage forms
FormRouteStrength
PowderOral
Injection, solutionIntramuscular; Intravenous; Subcutaneous500 mg/mL
Injection, solutionIntravenous500 mg/mL
SolutionIntramuscular; Intravenous500 mg
SolutionIntramuscular; Intravenous; Subcutaneous500 mg
PowderOral5 g
LiquidIntramuscular; Intravenous
ElixirOral
TabletOral166.7 mg
PowderTopical.375 g/75g
Powder, for solutionIntramuscular; Intravenous
Powder, for solutionIntravenous
TabletOral300 mg
TabletOral600 mg
Tablet, effervescentOral1000 mg
GranuleOral
PowderOral272 mg
TabletOral350 mg
TabletOral500 mg
WaferOral500 mg
LiquidOral50 mg
CapsuleOral375 mg
TabletOral333 mg
PowderOral1.25 g
PowderOral4.5 g
PowderOral825 mg
TabletOral5.7 mg
Solution / dropsOral50 mg
Kit
TabletOral
CapsuleOral120 mg
WaferOral
Kit
CapsuleOral200 mg
Tablet, effervescentOral1 g
Capsule, delayed release pelletsOral
Powder, for solutionOral
Tablet, extended releaseOral
Tablet, film coatedOral
SyrupOral
PowderOral15 mg
TabletOral200 mg
TabletOral15 mg
TabletOral125 mg
Kit; powderOral
Kit; powder, for solutionOral
TabletOral750 mg
LiquidOral60 mg
Tablet, effervescentOral500 mg
Tablet, chewableOral
LiquidOral250 mg
LiquidOral100 mg
Liquid; tabletOral
LiquidIntravenous
Injection, powder, lyophilized, for solutionIntravenous
LiquidIntramuscular; Intravenous; Subcutaneous500 mg
SolutionIntravenous250 mg
Tablet, chewableOral30 mg
Solution / dropsOral
SolutionIntravenous
Granule, effervescentOral
LiquidOral
SolutionOral
Capsule, gelatin coatedOral
TabletOral250 mg
CapsuleOral660 mg
CapsuleOral
CapsuleOral25 mg
PowderOral1000 mg
LiquidTopical
TabletOral150 mg
Injection, solutionIntravenous
Tablet, effervescentOral
PowderOral888.8 mg
EmulsionTopical
Tablet, coatedOral
KitOral
KitOral30 mg
LozengeOral100 mg
CapsuleOral650 mg
TabletOral50 mg
CapsuleOral8 mg
Capsule; liquidOral
Capsule, extended releaseOral
SolutionOral0.3 mg
Tablet, extended releaseOral1 g
LiquidOral550 mg
Capsule, liquid filledOral
LiquidIntramuscular; Intravenous250 mg
CapsuleOral1000 mg
CapsuleOral1 g
CapsuleOral100 mg
TabletOral1.5 g
CapsuleOral250 mg
TabletOral400 mg
TabletOral60 mg
GranuleOral1000 mg
PowderOral1.3 g
PowderOral100 %
PowderOral1200 mg
PowderOral2 g
PowderOral3 g
PowderOral4 g
Tablet, extended releaseOral1.8 g
PowderOral1250 mg
Capsule, extended releaseOral500 mg
TabletOral100 mg
TabletOral1000 mg
Tablet, extended releaseOral1.5 g
PowderOral1 g
Tablet, extended releaseOral1000 mg
TabletOral1 g
LiquidOral1 g
CapsuleOral150 mg
CapsuleOral500 mg
LiquidOral500 mg
Tablet, extended releaseOral500 mg
LozengeOral
Prices
Unit descriptionCostUnit
Cenolate 500 mg/1 ml ampul1.74USD ml
Cenolate 1 gm/2 ml ampul1.21USD ml
Calcium ascorbate powder0.79USD g
Ascorbic acid 222 mg/ml vial0.35USD ml
Ascor l 500 500 mg/ml vial0.24USD ml
Vitamin c 1500 mg tablet sa0.22USD tablet
CVS Pharmacy vit c ener boost 1000 mg0.21USD each
Cemill+bioflavonoids tablet0.09USD tablet
Vitamin c 1000 mg tablet sa0.09USD tablet
Cemill-1000 tablet0.08USD tablet
Vitamin c 1000 mg tablet0.08USD tablet
Cemill-500 tablet sa0.07USD tablet
CVS Pharmacy vitamin c 1000 mg tablet chw0.06USD tablet
Vitamin c 1000 mg caplet0.06USD caplet
Ascorbic acid 500 mg tablet0.04USD tablet
CVS Pharmacy vitamin c 1000 mg caplet0.04USD caplet
Pv ester-c 500 mg tablet0.04USD tablet
Vitamin c 500 mg chew tablet0.04USD tablet
Vitamin c 500 mg tablet0.04USD tablet
Vitamin c drops0.04USD tablet
Ra vitamin c cough drops0.03USD tablet
Vitamin c 250 mg tablet0.03USD tablet
Vitamin c 250 mg tablet chew0.03USD tablet
CVS Pharmacy vitamin c 500 mg caplet0.02USD caplet
CVS Pharmacy vitamin c 500 mg tablet0.02USD tablet
Ra vitamin c 100 mg tablet0.02USD tablet
Vicks vitamin c 60 mg drops0.02USD tablet
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
Patent NumberPediatric ExtensionApprovedExpires (estimated)
US7169381 No2004-09-012024-09-01Us
US7658914 No2004-09-012024-09-01Us

Properties

State
Solid
Experimental Properties
PropertyValueSource
melting point (°C)191 dec °CPhysProp
water solubility4E+005 mg/L (at 40 °C)MERCK INDEX (1996)
logP-1.85AVDEEF,A (1997)
pKa4.7 (at 10 °C)KORTUM,G ET AL (1961)
Predicted Properties
PropertyValueSource
Water Solubility245.0 mg/mLALOGPS
logP-1.6ALOGPS
logP-1.9ChemAxon
logS0.14ALOGPS
pKa (Strongest Acidic)4.36ChemAxon
pKa (Strongest Basic)-3ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count5ChemAxon
Hydrogen Donor Count4ChemAxon
Polar Surface Area107.22 Å2ChemAxon
Rotatable Bond Count2ChemAxon
Refractivity37.03 m3·mol-1ChemAxon
Polarizability14.93 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
PropertyValueProbability
Human Intestinal Absorption+0.6559
Blood Brain Barrier+0.8532
Caco-2 permeable-0.771
P-glycoprotein substrateNon-substrate0.6077
P-glycoprotein inhibitor INon-inhibitor0.9097
P-glycoprotein inhibitor IINon-inhibitor0.9807
Renal organic cation transporterNon-inhibitor0.9008
CYP450 2C9 substrateNon-substrate0.8133
CYP450 2D6 substrateNon-substrate0.8696
CYP450 3A4 substrateNon-substrate0.6361
CYP450 1A2 substrateNon-inhibitor0.8958
CYP450 2C9 inhibitorNon-inhibitor0.9478
CYP450 2D6 inhibitorNon-inhibitor0.9347
CYP450 2C19 inhibitorNon-inhibitor0.9383
CYP450 3A4 inhibitorNon-inhibitor0.9662
CYP450 inhibitory promiscuityLow CYP Inhibitory Promiscuity0.9249
Ames testNon AMES toxic0.8941
CarcinogenicityNon-carcinogens0.9417
BiodegradationReady biodegradable0.9526
Rat acute toxicity1.3059 LD50, mol/kg Not applicable
hERG inhibition (predictor I)Weak inhibitor0.9676
hERG inhibition (predictor II)Non-inhibitor0.9286
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397 )

Spectra

Mass Spec (NIST)
Download (8.32 KB)
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
GC-MS Spectrum - EI-BGC-MSsplash10-004i-4900000000-e99089fd55560fb70cfe
GC-MS Spectrum - GC-EI-TOFGC-MSsplash10-0002-0912000000-baa8cffda0478e1bc197
GC-MS Spectrum - GC-EI-TOFGC-MSsplash10-00di-9400000000-8ff8f48bfa2dd4fd3cf5
GC-MS Spectrum - GC-EI-TOFGC-MSsplash10-00di-9400000000-c1dc72c6cbc49fbf3454
GC-MS Spectrum - GC-EI-TOFGC-MSsplash10-00di-9400000000-b207f4024993c5a74769
GC-MS Spectrum - GC-EI-TOFGC-MSsplash10-0002-0911000000-9af0c08e85e0c51a25c4
Predicted LC-MS/MS Spectrum - 10V, PositivePredicted LC-MS/MSNot Available
Predicted LC-MS/MS Spectrum - 20V, PositivePredicted LC-MS/MSNot Available
Predicted LC-MS/MS Spectrum - 40V, PositivePredicted LC-MS/MSNot Available
Predicted LC-MS/MS Spectrum - 10V, NegativePredicted LC-MS/MSNot Available
Predicted LC-MS/MS Spectrum - 20V, NegativePredicted LC-MS/MSNot Available
Predicted LC-MS/MS Spectrum - 40V, NegativePredicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of organic compounds known as butenolides. These are dihydrofurans with a carbonyl group at the C2 carbon atom.
Kingdom
Organic compounds
Super Class
Organoheterocyclic compounds
Class
Dihydrofurans
Sub Class
Furanones
Direct Parent
Butenolides
Alternative Parents
Vinylogous acids / Enoate esters / Secondary alcohols / Lactones / Enediols / 1,2-diols / Oxacyclic compounds / Monocarboxylic acids and derivatives / Primary alcohols / Organic oxides
show 2 more
Substituents
2-furanone / Vinylogous acid / Alpha,beta-unsaturated carboxylic ester / Enoate ester / 1,2-diol / Carboxylic acid ester / Enediol / Secondary alcohol / Lactone / Carboxylic acid derivative
show 10 more
Molecular Framework
Aliphatic heteromonocyclic compounds
External Descriptors
ascorbic acid (CHEBI:29073 ) / Water-soluble vitamins (C00072 )

Targets

Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Procollagen-proline 4-dioxygenase activity
Specific Function
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Gene Name
P4HA1
Uniprot ID
P13674
Uniprot Name
Prolyl 4-hydroxylase subunit alpha-1
Molecular Weight
61048.775 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Sodium-dependent l-ascorbate transmembrane transporter activity
Specific Function
Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate.
Gene Name
SLC23A1
Uniprot ID
Q9UHI7
Uniprot Name
Solute carrier family 23 member 1
Molecular Weight
64830.445 Da
References
  1. Kang JS, Kim HN, Jung da J, Kim JE, Mun GH, Kim YS, Cho D, Shin DH, Hwang YI, Lee WJ: Regulation of UVB-induced IL-8 and MCP-1 production in skin keratinocytes by increasing vitamin C uptake via the redistribution of SVCT-1 from the cytosol to the membrane. J Invest Dermatol. 2007 Mar;127(3):698-706. Epub 2006 Sep 28. [PubMed:17008880 ]
  2. Johnston L, Laverty G: Vitamin C transport and SVCT1 transporter expression in chick renal proximal tubule cells in culture. Comp Biochem Physiol A Mol Integr Physiol. 2007 Mar;146(3):327-34. Epub 2006 Dec 5. [PubMed:17258485 ]
  3. Savini I, Rossi A, Pierro C, Avigliano L, Catani MV: SVCT1 and SVCT2: key proteins for vitamin C uptake. Amino Acids. 2008 Apr;34(3):347-55. Epub 2007 Jun 1. [PubMed:17541511 ]
  4. Perez MJ, Castano B, Gonzalez-Buitrago JM, Marin JJ: Multiple protective effects of melatonin against maternal cholestasis-induced oxidative stress and apoptosis in the rat fetal liver-placenta-maternal liver trio. J Pineal Res. 2007 Sep;43(2):130-9. [PubMed:17645691 ]
  5. Steiling H, Longet K, Moodycliffe A, Mansourian R, Bertschy E, Smola H, Mauch C, Williamson G: Sodium-dependent vitamin C transporter isoforms in skin: Distribution, kinetics, and effect of UVB-induced oxidative stress. Free Radic Biol Med. 2007 Sep 1;43(5):752-62. Epub 2007 May 10. [PubMed:17664139 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
Actions
Activator
General Function
Protein homodimerization activity
Specific Function
Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecu...
Gene Name
PLOD1
Uniprot ID
Q02809
Uniprot Name
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
Molecular Weight
83549.55 Da
References
  1. Salavoura K, Valari M, Kolialexi A, Mavrou A, Kitsiou S: A case of Ehlers Danlos syndrome type VI. Genet Couns. 2006;17(3):291-4. [PubMed:17100196 ]
  2. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
Kind
Protein
Organism
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Pharmacological action
Unknown
General Function
Hyaluronate lyase activity
Specific Function
Not Available
Gene Name
Not Available
Uniprot ID
Q54873
Uniprot Name
Hyaluronate lyase
Molecular Weight
120770.645 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
  3. Li S, Taylor KB, Kelly SJ, Jedrzejas MJ: Vitamin C inhibits the enzymatic activity of Streptococcus pneumoniae hyaluronate lyase. J Biol Chem. 2001 May 4;276(18):15125-30. Epub 2001 Jan 12. [PubMed:11278838 ]
  4. Okorukwu ON, Vercruysse KP: Effects of ascorbic acid and analogs on the activity of testicular hyaluronidase and hyaluronan lyase on hyaluronan. J Enzyme Inhib Med Chem. 2003 Aug;18(4):377-82. [PubMed:14567553 ]
  5. Botzki A, Rigden DJ, Braun S, Nukui M, Salmen S, Hoechstetter J, Bernhardt G, Dove S, Jedrzejas MJ, Buschauer A: L-Ascorbic acid 6-hexadecanoate, a potent hyaluronidase inhibitor. X-ray structure and molecular modeling of enzyme-inhibitor complexes. J Biol Chem. 2004 Oct 29;279(44):45990-7. Epub 2004 Aug 18. [PubMed:15322107 ]
5. DNA
Kind
Nucleotide
Organism
Human
Pharmacological action
Unknown
General Function:
Used for biological information storage.
Specific Function:
DNA contains the instructions needed for an organism to develop, survive and reproduce.
Molecular Weight:
2.15 x 1012 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
  3. Guarnieri S, Loft S, Riso P, Porrini M, Risom L, Poulsen HE, Dragsted LO, Moller P: DNA repair phenotype and dietary antioxidant supplementation. Br J Nutr. 2008 May;99(5):1018-24. Epub 2007 Oct 10. [PubMed:17925050 ]
  4. Singh S, Rana SV: Amelioration of arsenic toxicity by L-Ascorbic acid in laboratory rat. J Environ Biol. 2007 Apr;28(2 Suppl):377-84. [PubMed:17929753 ]
  5. Manna P, Sinha M, Sil PC: Protection of arsenic-induced hepatic disorder by arjunolic acid. Basic Clin Pharmacol Toxicol. 2007 Nov;101(5):333-8. [PubMed:17910617 ]
Kind
Protein
Organism
Streptomyces rubiginosus
Pharmacological action
Unknown
General Function
Xylose isomerase activity
Specific Function
Involved in D-xylose catabolism.
Gene Name
xylA
Uniprot ID
P24300
Uniprot Name
Xylose isomerase
Molecular Weight
43226.915 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Procollagen-lysine 5-dioxygenase activity
Specific Function
Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecu...
Gene Name
PLOD2
Uniprot ID
O00469
Uniprot Name
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
Molecular Weight
84685.07 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Phytanoyl-coa dioxygenase activity
Specific Function
Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA.
Gene Name
PHYH
Uniprot ID
O14832
Uniprot Name
Phytanoyl-CoA dioxygenase, peroxisomal
Molecular Weight
38538.065 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Procollagen-lysine 5-dioxygenase activity
Specific Function
Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecu...
Gene Name
PLOD3
Uniprot ID
O60568
Uniprot Name
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
Molecular Weight
84784.505 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Zinc ion binding
Specific Function
Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
Gene Name
BBOX1
Uniprot ID
O75936
Uniprot Name
Gamma-butyrobetaine dioxygenase
Molecular Weight
44714.6 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
  3. Dunn WA, Rettura G, Seifter E, Englard S: Carnitine biosynthesis from gamma-butyrobetaine and from exogenous protein-bound 6-N-trimethyl-L-lysine by the perfused guinea pig liver. Effect of ascorbate deficiency on the in situ activity of gamma-butyrobetaine hydroxylase. J Biol Chem. 1984 Sep 10;259(17):10764-70. [PubMed:6432788 ]
  4. Vaz FM, van Gool S, Ofman R, IJlst L, Wanders RJ: Carnitine biosynthesis. Purification of gamma-butyrobetaine hydroxylase from rat liver. Adv Exp Med Biol. 1999;466:117-24. [PubMed:10709635 ]
  5. Rebouche CJ: Ascorbic acid and carnitine biosynthesis. Am J Clin Nutr. 1991 Dec;54(6 Suppl):1147S-1152S. [PubMed:1962562 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
L-ascorbic acid binding
Specific Function
Conversion of dopamine to noradrenaline.
Gene Name
DBH
Uniprot ID
P09172
Uniprot Name
Dopamine beta-hydroxylase
Molecular Weight
69064.45 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
  3. Suzuki E, Kurata T, Shibata M, Mori M, Arakawa N: Activities of D- and L-xyloascorbic acid and D- and L-araboascorbic acid as a cofactor for dopamine beta-hydroxylase reaction. J Nutr Sci Vitaminol (Tokyo). 1997 Oct;43(5):491-6. [PubMed:9505234 ]
  4. Pettingill TM, Strange RW, Blackburn NJ: Carbonmonoxy dopamine beta-hydroxylase. Structural characterization by Fourier transform infrared, fluorescence, and x-ray absorption spectroscopy. J Biol Chem. 1991 Sep 15;266(26):16996-7003. [PubMed:1894598 ]
  5. Feng J, Shi J, Sirimanne SR, Mounier-Lee CE, May SW: Kinetic and stereochemical studies on novel inactivators of C-terminal amidation. Biochem J. 2000 Sep 1;350 Pt 2:521-30. [PubMed:10947967 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Zinc ion binding
Specific Function
Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutat...
Gene Name
PAM
Uniprot ID
P19021
Uniprot Name
Peptidyl-glycine alpha-amidating monooxygenase
Molecular Weight
108331.35 Da
References
  1. Romero I, Teresa Sanchez-Ballesta M, Maldonado R, Isabel Escribano M, Merodio C: Anthocyanin, antioxidant activity and stress-induced gene expression in high CO2-treated table grapes stored at low temperature. J Plant Physiol. 2008;165(5):522-30. Epub 2007 Jun 13. [PubMed:17570561 ]
  2. Floryszak-Wieczorek J, Milczarek G, Arasimowicz M, Ciszewski A: Do nitric oxide donors mimic endogenous NO-related response in plants? Planta. 2006 Nov;224(6):1363-72. Epub 2006 Jun 14. [PubMed:16773376 ]
  3. Crespo A, Marti MA, Roitberg AE, Amzel LM, Estrin DA: The catalytic mechanism of peptidylglycine alpha-hydroxylating monooxygenase investigated by computer simulation. J Am Chem Soc. 2006 Oct 4;128(39):12817-28. [PubMed:17002377 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Protein complex binding
Specific Function
Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in...
Gene Name
P3H1
Uniprot ID
Q32P28
Uniprot Name
Prolyl 3-hydroxylase 1
Molecular Weight
83393.195 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Specific Function
Not Available
Gene Name
OGFOD2
Uniprot ID
Q6N063
Uniprot Name
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2
Molecular Weight
38996.065 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Ferrous iron binding
Specific Function
Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has s...
Gene Name
ALKBH2
Uniprot ID
Q6NS38
Uniprot Name
DNA oxidative demethylase ALKBH2
Molecular Weight
29322.22 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Procollagen-proline 3-dioxygenase activity
Specific Function
Shows prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly-sequences in collagens, especially types II, IV and V.
Gene Name
P3H2
Uniprot ID
Q8IVL5
Uniprot Name
Prolyl 3-hydroxylase 2
Molecular Weight
80983.685 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Procollagen-proline 3-dioxygenase activity
Specific Function
Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly-sequences in collagens, especially types IV and V.
Gene Name
P3H3
Uniprot ID
Q8IVL6
Uniprot Name
Prolyl 3-hydroxylase 3
Molecular Weight
81835.705 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Peptidyl-proline dioxygenase activity
Specific Function
Prolyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro-62' of small ribosomal subunit RPS23, thereby regulating protein translation termination efficiency. Involved in stress granule formation.
Gene Name
OGFOD1
Uniprot ID
Q8N543
Uniprot Name
Prolyl 3-hydroxylase OGFOD1
Molecular Weight
63245.655 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Peptidyl-proline 4-dioxygenase activity
Specific Function
Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific prol...
Gene Name
EGLN2
Uniprot ID
Q96KS0
Uniprot Name
Egl nine homolog 2
Molecular Weight
43650.03 Da
References
  1. Nytko KJ, Spielmann P, Camenisch G, Wenger RH, Stiehl DP: Regulated function of the prolyl-4-hydroxylase domain (PHD) oxygen sensor proteins. Antioxid Redox Signal. 2007 Sep;9(9):1329-38. [PubMed:17627474 ]
  2. Bruegge K, Jelkmann W, Metzen E: Hydroxylation of hypoxia-inducible transcription factors and chemical compounds targeting the HIF-alpha hydroxylases. Curr Med Chem. 2007;14(17):1853-62. [PubMed:17627521 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
L-ascorbic acid binding
Specific Function
Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alk...
Gene Name
ALKBH3
Uniprot ID
Q96Q83
Uniprot Name
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3
Molecular Weight
33374.495 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Zinc ion binding
Specific Function
Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-...
Gene Name
KDM5D
Uniprot ID
Q9BY66
Uniprot Name
Lysine-specific demethylase 5D
Molecular Weight
174071.34 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Peptidyl-proline dioxygenase activity
Specific Function
Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific prol...
Gene Name
EGLN1
Uniprot ID
Q9GZT9
Uniprot Name
Egl nine homolog 1
Molecular Weight
46020.585 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Peptidyl-proline 4-dioxygenase activity
Specific Function
Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific prol...
Gene Name
EGLN3
Uniprot ID
Q9H6Z9
Uniprot Name
Egl nine homolog 3
Molecular Weight
27261.06 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Trimethyllysine dioxygenase activity
Specific Function
Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML).
Gene Name
TMLHE
Uniprot ID
Q9NVH6
Uniprot Name
Trimethyllysine dioxygenase, mitochondrial
Molecular Weight
49517.2 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
Specific Function
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sen...
Gene Name
P4HTM
Uniprot ID
Q9NXG6
Uniprot Name
Transmembrane prolyl 4-hydroxylase
Molecular Weight
56660.535 Da
References
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Transferase activity
Specific Function
LPH splits lactose in the small intestine.
Gene Name
LCT
Uniprot ID
P09848
Uniprot Name
Lactase-phlorizin hydrolase
Molecular Weight
218584.77 Da
References
  1. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. [PubMed:10592235 ]

Transporters

Kind
Protein
Organism
Human
Pharmacological action
Unknown
General Function
Sodium-dependent l-ascorbate transmembrane transporter activity
Specific Function
Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate.
Gene Name
SLC23A1
Uniprot ID
Q9UHI7
Uniprot Name
Solute carrier family 23 member 1
Molecular Weight
64830.445 Da
References
  1. Tsukaguchi H, Tokui T, Mackenzie B, Berger UV, Chen XZ, Wang Y, Brubaker RF, Hediger MA: A family of mammalian Na+-dependent L-ascorbic acid transporters. Nature. 1999 May 6;399(6731):70-5. [PubMed:10331392 ]
Drug created on June 13, 2005 07:24 / Updated on September 01, 2017 10:23