Fluoride ion

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

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Name
Fluoride ion
Accession Number
DB11257
Type
Small Molecule
Groups
Approved
Description

Having a chemical formula of F−, fluoride ion is the simplest inorganic, monatomic anion of fluorine with basic properties. It is considered a trace element. Fluoride ions are found in various minerals but are only present in trace amounts in water. Its various salt forms and minerals play numerous roles as chemical reagents, industrial chemicals, and commercial products. It also plays an essential physiological role, such as enhancing the resistance profile and strength of the surface tooth enamel.

Structure
Thumb
Synonyms
Not Available
Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing End
Topex Neutral pH Fluoride Gel MintGel9 mg/1gDentalDentsply Llc. Professional Division Trading As "Sultan Healthcare"1900-01-01Not applicableUs
Topex Neutral pH Fluoride Gel StrawberryGel9 mg/1gDentalDentsply Llc. Professional Division Trading As "Sultan Healthcare"1900-01-01Not applicableUs
Additional Data Available
  • Application Number
    Application Number

    A unique ID assigned by the FDA when a product is submitted for approval by the labeller.

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  • Product Code
    Product Code

    A governmentally-recognized ID which uniquely identifies the product within its regulatory market.

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Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Multi-VitaminFluoride ion (1.0 mg/1) + Ascorbic acid (60 mg/1) + Cyanocobalamin (4.5 ug/1) + DL-alpha tocopheryl acetate (15 [iU]/1) + Folic acid (0.3 mg/1) + Niacin (13.5 mg/1) + Pyridoxine (1.05 mg/1) + Riboflavin (1.2 mg/1) + Thiamine chloride (1.05 mg/1) + Vitamin A (2500 [iU]/1) + Vitamin D (400 [iU]/1)Tablet, chewableOralBoca Pharmacal, Inc.2011-09-062014-12-31Us
Multi-VitaminFluoride ion (0.50 mg/1) + Ascorbic acid (60 mg/1) + Cyanocobalamin (4.5 ug/1) + DL-alpha tocopheryl acetate (15 [iU]/1) + Folic acid (0.3 mg/1) + Niacin (13.5 mg/1) + Pyridoxine (1.05 mg/1) + Riboflavin (1.2 mg/1) + Thiamine chloride (1.05 mg/1) + Vitamin A (2500 [iU]/1) + Vitamin D (400 [iU]/1)Tablet, chewableOralBoca Pharmacal, Inc.2011-12-282015-06-30Us
Multi-Vitamin Fluoride and Iron DropsFluoride ion (0.25 mg/1mL) + Ascorbic acid (35 mg/1mL) + Cholecalciferol (400 [iU]/1mL) + Iron (10 mg/1mL) + Niacin (8 mg/1mL) + Pyridoxine (0.4 mg/1mL) + Riboflavin (0.6 mg/1mL) + Thiamine chloride (0.5 mg/1mL) + Vitamin A (1500 [iU]/1mL) + alpha-Tocopherol succinate (5 [iU]/1mL)SolutionOralBoca Pharmacal, Inc.2011-04-202015-08-31Us
Multi-Vitamin Fluoride DropsFluoride ion (0.5 mg/1mL) + Ascorbic acid (35 mg/1mL) + Cholecalciferol (400 [iU]/1mL) + Cyanocobalamin (2 ug/1mL) + Niacin (8 mg/1mL) + Pyridoxine (0.4 mg/1mL) + Riboflavin (0.6 mg/1mL) + Thiamine chloride (0.5 mg/1mL) + Vitamin A (1500 [iU]/1mL) + alpha-Tocopherol succinate (5 [iU]/1mL)SolutionOralBoca Pharmacal, Inc.2011-06-062015-08-31Us
Multi-Vitamin Fluoride DropsFluoride ion (0.25 mg/1mL) + Ascorbic acid (35 mg/1mL) + Cholecalciferol (400 [iU]/1mL) + Cyanocobalamin (2 ug/1mL) + Niacin (8 mg/1mL) + Pyridoxine (0.4 mg/1mL) + Riboflavin (0.6 mg/1mL) + Thiamine chloride (0.5 mg/1mL) + Vitamin A (1500 [iU]/1mL) + alpha-Tocopherol succinate (5 [iU]/1mL)SolutionOralBoca Pharmacal, Inc.2011-05-042016-03-31Us
Multi-Vitamin Fluoride DropsFluoride ion (0.25 mg/1mL) + Ascorbic acid (35 mg/1mL) + Cholecalciferol (400 [iU]/1mL) + Cyanocobalamin (2 ug/1mL) + Niacin (8 mg/1mL) + Pyridoxine (0.4 mg/1mL) + Riboflavin (0.6 mg/1mL) + Thiamine chloride (0.5 mg/1mL) + Vitamin A (1500 [iU]/1mL) + alpha-Tocopherol succinate (5 [iU]/1mL)SolutionOralH.J. Harkins Company2011-05-04Not applicableUs
Multi-Vitamin With FluorideFluoride ion (0.50 mg/1) + Ascorbic acid (60 mg/1) + Cyanocobalamin (4.5 ug/1) + Folic acid (0.3 mg/1) + Niacin (13.5 mg/1) + Pyridoxine (1.05 mg/1) + Riboflavin (1.2 mg/1) + Thiamine chloride (1.05 mg/1) + Vitamin A (2500 [iU]/1) + Vitamin D (400 [iU]/1) + alpha-Tocopherol acetate (15 [iU]/1)Tablet, chewableOralGolden State Medical Supply2010-12-292018-10-11Us
Multi-Vitamin With FluorideFluoride ion (0.25 mg/1) + Ascorbic acid (60 mg/1) + Cyanocobalamin (4.5 ug/1) + Folic acid (0.3 mg/1) + Niacin (13.5 mg/1) + Pyridoxine (1.05 mg/1) + Riboflavin (1.2 mg/1) + Thiamine chloride (1.05 mg/1) + Vitamin A (2500 [iU]/1) + Vitamin D (400 [iU]/1) + alpha-Tocopherol acetate (15 [iU]/1)Tablet, chewableOralGolden State Medical Supply2010-12-172018-10-11Us
Multi-Vitamin With FluorideFluoride ion (0.25 mg/1) + Ascorbic acid (60 mg/1) + Cyanocobalamin (4.5 ug/1) + DL-alpha tocopheryl acetate (15 [iU]/1) + Folic acid (0.3 mg/1) + Niacin (13.5 mg/1) + Pyridoxine (1.05 mg/1) + Riboflavin (1.2 mg/1) + Thiamine chloride (1.05 mg/1) + Vitamin A (2500 [iU]/1) + Vitamin D (400 [iU]/1)Tablet, chewableOralBoca Pharmacal, Inc.2011-12-282015-01-31Us
Multi-Vitamin With FluorideFluoride ion (1.0 mg/1) + Ascorbic acid (60 mg/1) + Cyanocobalamin (4.5 ug/1) + Folic acid (0.3 mg/1) + Niacin (13.5 mg/1) + Pyridoxine (1.05 mg/1) + Riboflavin (1.2 mg/1) + Thiamine chloride (1.05 mg/1) + Vitamin A (2500 [iU]/1) + Vitamin D (400 [iU]/1) + alpha-Tocopherol acetate (15 [iU]/1)Tablet, chewableOralGolden State Medical Supply2010-12-172018-10-11Us
Categories
Not Available
UNII
Q80VPU408O
CAS number
16984-48-8
Weight
Average: 18.9984
Monoisotopic: 18.998403205
Chemical Formula
F
InChI Key
KRHYYFGTRYWZRS-UHFFFAOYSA-M
InChI
InChI=1S/FH/h1H/p-1
IUPAC Name
fluoride
SMILES
[F-]

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Additional Data Available
Adverse Effects

Comprehensive structured data on known drug adverse effects with statistical prevalence. MedDRA and ICD10 ids are provided for adverse effect conditions and symptoms.

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Additional Data Available
Contraindications

Structured data covering drug contraindications. Each contraindication describes a scenario in which the drug is not to be used. Includes restrictions on co-administration, contraindicated populations, and more.

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Additional Data Available
Blackbox Warnings

Structured data representing warnings from the black box section of drug labels. These warnings cover important and dangerous risks, contraindications, or adverse effects.

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Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

References

General References
Not Available
External Links
Human Metabolome Database
HMDB0000662
KEGG Compound
C00742
PubChem Compound
28179
PubChem Substance
347827955
ChemSpider
26214
BindingDB
26978
ChEBI
17051
ChEMBL
CHEMBL1362
HET
F
Wikipedia
Fluoride
PDB Entries
1bs3 / 1e6a / 1lh5 / 1nel / 1t5g / 2akz / 2au6 / 2au9 / 2auu / 2dqz
show 60 more

Clinical Trials

Clinical Trials
Not Available

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
SolutionOral
Tablet, chewableOral
Suspension / dropsOral
GelDental9 mg/1g
LiquidOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP0.15ChemAxon
pKa (Strongest Acidic)3.17ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0.87 m3·mol-1ChemAxon
Polarizability0.44 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Taxonomy

Description
This compound belongs to the class of inorganic compounds known as homogeneous halogens. These are inorganic non-metallic compounds in which the largest atom is a nobel gas.
Kingdom
Inorganic compounds
Super Class
Homogeneous non-metal compounds
Class
Homogeneous halogens
Sub Class
Not Available
Direct Parent
Homogeneous halogens
Alternative Parents
Not Available
Substituents
Homogeneous halogen
Molecular Framework
Not Available
External Descriptors
halide anion, monoatomic fluorine (CHEBI:17051) / an anion (F-)

Drug created on December 03, 2015 09:51 / Updated on December 02, 2019 08:59