Ethyl chloride

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Ethyl chloride
Accession Number
DB13259
Type
Small Molecule
Groups
Approved, Experimental, Investigational
Description

Ethyl chloride, or chloroethane, has a chemical formula C2H5Cl. It was commonly used in the production of tetraethyllead (TEL), which is an additive for gasoline. It was also used in other commerical applications as a chemical reagent. It is still used in the treatment of cellulose to make ethylcellulose for commercial products. Ethyl chloride is used as a diagnostic tool to detect a dead tooth with nonviable pulp.

Structure
Thumb
Synonyms
  • chloroethane
  • monochloroethane
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing End
Tuffner Clear SprayEthyl chloride (12 %) + Benzoin (3 %)AerosolTopicalMueller Sports Medicine, Inc.1970-12-312003-08-01Canada
Categories
UNII
46U771ERWK
CAS number
75-00-3
Weight
Average: 64.514
Monoisotopic: 64.007977867
Chemical Formula
C2H5Cl
InChI Key
HRYZWHHZPQKTII-UHFFFAOYSA-N
InChI
InChI=1S/C2H5Cl/c1-2-3/h2H2,1H3
IUPAC Name
chloroethane
SMILES
CCCl

Pharmacology

Indication
Not Available
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half life
Not Available
Clearance
Not Available
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
DrugInteraction
7-NitroindazoleThe risk or severity of adverse effects can be increased when 7-Nitroindazole is combined with Ethyl chloride.
AcepromazineThe risk or severity of adverse effects can be increased when Acepromazine is combined with Ethyl chloride.
AceprometazineThe risk or severity of adverse effects can be increased when Aceprometazine is combined with Ethyl chloride.
AcetazolamideThe risk or severity of adverse effects can be increased when Ethyl chloride is combined with Acetazolamide.
AdipiplonThe risk or severity of adverse effects can be increased when Adipiplon is combined with Ethyl chloride.
AgomelatineThe risk or severity of adverse effects can be increased when Agomelatine is combined with Ethyl chloride.
AlaproclateThe risk or severity of adverse effects can be increased when Ethyl chloride is combined with Alaproclate.
AlfaxaloneThe risk or severity of adverse effects can be increased when Alfaxalone is combined with Ethyl chloride.
AlfentanilThe risk or severity of adverse effects can be increased when Alfentanil is combined with Ethyl chloride.
AlimemazineThe risk or severity of adverse effects can be increased when Ethyl chloride is combined with Alimemazine.
Food Interactions
Not Available

References

General References
Not Available
External Links
KEGG Compound
C18248
PubChem Compound
6337
PubChem Substance
347829290
ChemSpider
6097
ChEBI
47554
ChEMBL
CHEMBL46058
Wikipedia
Chloroethane
ATC Codes
N01BX01 — Ethyl chloride

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4TerminatedTreatmentShoulder Pain1
Not AvailableCompletedTreatmentAnaesthesia therapy / Pain1
Not AvailableCompletedTreatmentPain1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage forms
FormRouteStrength
AerosolTopical
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility14.1 mg/mLALOGPS
logP1.47ALOGPS
logP1.19ChemAxon
logS-0.66ALOGPS
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity16.06 m3·mol-1ChemAxon
Polarizability6.42 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
GC-MS Spectrum - EI-BGC-MSsplash10-004i-9000000000-189a942366091e0718c5
Mass Spectrum (Electron Ionization)MSsplash10-004i-9000000000-11f0eb48855aebd37893
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available
1H NMR Spectrum1D NMRNot Applicable

Taxonomy

Description
This compound belongs to the class of organic compounds known as organochlorides. These are compounds containing a chemical bond between a carbon atom and a chlorine atom.
Kingdom
Organic compounds
Super Class
Organohalogen compounds
Class
Organochlorides
Sub Class
Not Available
Direct Parent
Organochlorides
Alternative Parents
Hydrocarbon derivatives / Alkyl chlorides
Substituents
Hydrocarbon derivative / Organochloride / Alkyl halide / Alkyl chloride / Aliphatic acyclic compound
Molecular Framework
Aliphatic acyclic compounds
External Descriptors
chloroethanes (CHEBI:47554)

Drug created on June 23, 2017 14:38 / Updated on October 01, 2018 15:28