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Displaying drugs 326 - 350 of 15161 in total

Metformin

Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin...
Approved
Matched Description: … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management ... It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and ... [A36559] Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval …
Matched Mixtures name: … Glyburide and Metformin ... Glyburide and Metformin ... Glyburide and Metformin …
Matched Categories: … metformin and acarbose ... Alimentary Tract and Metabolism ... metformin and evogliptin ... metformin and gemigliptin ... metformin and linagliptin …

Laronidase

Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology in a Chinese hamster ovary cell line. Laronidase is a glycoprotein with a molecular weight of approximately 83 kD. The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes it, are identical...
Approved
Matched Description: … it, are identical to a polymorphic form of human a-L-iduronidase. ... Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology ... The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Quinapril

Quinapril is the ethyl ester prodrug of the non-sulfhydryl angiotensin converting enzyme inhibitor quinaprilat.[L8420,L8423] It is used to treat hypertension and heart failure.[L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. Quinapril was granted FDA approval...
Approved
Investigational
Matched Description: … [L8420,L8423] It is used to treat hypertension and heart failure. …
Matched Mixtures name: … Quinapril and Hydrochlorothiazide ... Quinapril and Hydrochlorothiazide ... Quinapril and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Diuretics ... quinapril and diuretics …

Ethinylestradiol

Ethinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering. It was developed in an effort to create an estrogen with greater oral bioavailability. These properties were achieved by the substitution of an ethinyl group at carbon 17 of estradiol. Ethinylestradiol soon replaced mestranol in...
Approved
Matched Iupac: … (1R,3aS,3bR,9bS,11aS)-1-ethynyl-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene …
Matched Description: … Ethinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering …
Matched Mixtures name: … Norethindrone and Ethinyl Estradiol and Ferrous Fumarate ... Norethindrone and Ethinyl Estradiol and Ferrous Fumarate ... Levonorgestrel and Ethinyl Estradiol and Ethinyl Estradiol …
Matched Categories: … Hormones and Related Agents ... dienogest and ethinylestradiol ... gestodene and ethinylestradiol ... megestrol and ethinylestradiol ... megestrol and ethinylestradiol …

Sebelipase alfa

The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism of lipids, and its absence or deficiency results in the accumulation of lipids in various organs. This lipid accumulation can lead to end-organ damage in the form of liver dysfunction or malabsorption secondary...
Approved
Investigational
Matched Description: … This lipid accumulation can lead to end-organ damage in the form of liver dysfunction or malabsorption ... [L39337] Sebelipase alfa is a recombinant form LAL approved for the treatment of LAL deficiency. ... It was first approved by both the FDA and EMA in 2015 and is marketed under the brand name Kanuma (Alexion …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Gramicidin D

Gramcidin D is a heterogeneous mixture of three antibiotic compounds, gramicidins A, B and C, making up 80%, 6%, and 14% respectively all of which are obtained from the soil bacterial species Bacillus brevis and called collectively gramicidin D. Gramcidins are 15 residue peptides with alternating D and L amino...
Approved
Matched Description: … hydrophobic interior of the cellular lipid bilayer to form a β-helix. ... and called collectively gramicidin D. ... as a topical antibiotic and is also found in Polysporin ophthalmic solution. …
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Gramicidin ... Neomycin and Polymyxin B Sulfates and Gramicidin ... Neomycin and Polymyxin B Sulfates and Gramicidin …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Magnesium

Magnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas, apples, carrots, broccoli, and leafy...
Approved
Experimental
Investigational
Matched Description: … and magnesium carbonate. ... [A32810] Further, the mineral helps regulate blood pressure and is necessary for RNA, DNA and protein ... Magnesium is classified as an alkaline earth metal and has 2 hydration shells. …
Matched Mixtures name: … Hvp Chelated Cal/mag With Zinc and Vitamins C and D ... CALCIUM AND MAGNESIUM PLUS C,POTASSIUM AND ZINC TABLET ... Vitamin and Mineral Drink Mix …

Influenza A virus A/California/7/2009 (H1N1)-like hemagglutinin antigen (formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated …

Chromium

Chromium is a transition element with the chemical symbol Cr and atomic number 24 that belongs to Group 6 of the periodic table. It is used in various chemical, industrial and manufacturing applications such as wood preservation and metallurgy. The uses of chromium compounds depend on the valency of chromium,...
Approved
Matched Description: … It is used in various chemical, industrial and manufacturing applications such as wood preservation and ... non-pregnant female are 35 μg and 25 μg, respectively [L1986]. ... Chromium is a transition element with the chemical symbol Cr and atomic number 24 that belongs to Group …
Matched Mixtures name: … Chromium and Vanadium (combo) ... Vitamin and Mineral Drink Mix ... Prenatal Vitamin and Mineral Supplement …
Matched Categories: … Diet, Food, and Nutrition …

Perphenazine

An antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.
Approved
Matched Description: … An antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine. …
Matched Mixtures name: … Perphenazine and Amitriptyline Hydrochloride ... Perphenazine and Amitriptyline Hydrochloride ... Perphenazine and Amitriptyline Hydrochloride …

Copper

Copper is a transition metal and a trace element in the body. It is important to the function of many enzymes including cytochrome c oxidase, monoamine oxidase and superoxide dismutase [FDA Label]. Copper is commonly used in contraceptive intrauterine devices (IUD) .
Approved
Investigational
Matched Description: … Copper is a transition metal and a trace element in the body. ... It is important to the function of many enzymes including cytochrome c oxidase, monoamine oxidase and …
Matched Mixtures name: … Trace Minerals Et/and B12 Tab ... Vitamin and Mineral Drink Mix ... Multiple Vitamins and Minerals Tab …
Matched Categories: … Diet, Food, and Nutrition …

Prednisolone phosphate

Prednisolone phosphate is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone phosphate was granted FDA Approval on 19 December 1973.
Approved
Vet approved
Matched Description: … glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and …
Matched Mixtures name: … Sulfacetamide Sodium and Prednisolone Sodium Phosphate ... Sulfacetamide Sodium and Prednisolone Sodium Phosphate ... Sulfacetamide Sodium and Prednisolone Sodium Phosphate …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Sodium molybdate

Approved
Experimental
Matched Mixtures name: … Multiple Vitamins and Minerals ... Prenatal Vitamin and Mineral Supplement ... Multivitamins and Minerals Tablets …

Oxyphenonium

A quaternary ammonium anticholinergic agent with peripheral side effects similar to those of atropine. It is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. The drug has also been used in the form of eye drops for mydriatic effect. [PubChem]
Approved
Matched Description: … The drug has also been used in the form of eye drops for mydriatic effect. [PubChem] ... It is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms …
Matched Categories: … Alimentary Tract and Metabolism …

Calcium citrate

Calcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements.
Approved
Investigational
Matched Mixtures name: … Calcium and Mag-potass and Zinc Cap ... Calcium and Magnesium Citrate and Vitamin D 250mg/125mg/200iu ... Calcium, Magnesium, Zinc and D …
Matched Categories: … Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... ascorbic acid (vit C) and calcium ... Calcium-Regulating Hormones and Agents …

Podofilox

A lignan found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and...
Approved
Matched Description: … and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives. ... It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. ... It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts …
Matched Categories: … Skin and Mucous Membrane Agents …

Metyrapone

An inhibitor of the enzyme steroid 11-beta-monooxygenase. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome.
Approved
Investigational
Matched Iupac: … 2-methyl-1,2-bis(pyridin-3-yl)propan-1-one …

Racepinephrine

Racepinephrine is a racemic mixture consisting of d-DB00668 and l-DB00668 enantiomers. Epinephrine is a non-selective α- and β-adrenergic receptor agonist. It is a bronchodilator used in the temporary relief of mild symptoms of intermittent asthma including wheezing, tightness of chest and shortness of breath. It is an active ingredient in...
Approved
Matched Description: … Epinephrine is a non-selective α- and β-adrenergic receptor agonist. ... Racepinephrine is a racemic mixture consisting of d-[DB00668] and l-[DB00668] enantiomers. ... the temporary relief of mild symptoms of intermittent asthma including wheezing, tightness of chest and …
Matched Mixtures name: … Gingibraid W Epineph and Alum 1e ... Gingibraid W Epineph and Alum 2e ... Gingibraid W Epineph and Alum 3e …
Matched Categories: … Epinephrine and similars ... Alpha-and Beta-adrenergic Agonists …

Abacavir

Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. In vivo, abacavir sulfate dissociates to its free base, abacavir.
Approved
Investigational
Matched Description: … Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and ... Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration …
Matched Mixtures name: … Abacavir and Lamivudine ... Abacavir and Lamivudine ... Abacavir and lamivudine …
Matched Categories: … lamivudine and abacavir ... zidovudine, lamivudine and abacavir ... lamivudine, abacavir and dolutegravir ... Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …

Ferrous sulfate anhydrous

Iron deficiency anemia is a large public health concern worldwide, especially in young children, infants, and women of childbearing age. This type of anemia occurs when iron intake, iron stores, and iron loss do not adequately support the formation of erythrocytes, also known as red blood cells. Ferrous sulfate is...
Approved
Matched Description: … deficiency anemia is a large public health concern worldwide, especially in young children, infants, and ... It is the gold standard of oral iron therapy in the UK and many other countries.[L2234,L2246] ... [A190804] This type of anemia occurs when iron intake, iron stores, and iron loss do not adequately support …
Matched Mixtures name: … Tri-Vitamin with iron and fluoride ... Multi-Vit with Fluoride and Iron ... Multiple Vitamins and Minerals Tab …

Pramocaine

Pramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders. Pramocaine is available by itself and in combination with other medications...
Approved
Matched Description: … Pramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. ... bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders ... It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect …
Matched Mixtures name: … Bite and Itch ... Up and Up Hemorrhoidal ... Antibiotic, Pain and Scar …
Matched Categories: … Antipruritics and Local Anesthetics ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Gadoxetic acid

Gadoxetic acid (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which its salt form, gadoxetate disodium, is used for intravenous injection. Ethoxybenzyl diethylenetriaminepentaacetic acid is the moiety that chelates with a gadolinium ion and forms a stable complex with it to make up the drug. Gadoxetate is a...
Approved
Matched Description: … (gadoxetate) is a paramagnetic gadolinium-containing ionic linear contrast agent in which its salt form ... [A263146] Gadoxetic acid, under the form gadoxetate disodium, is marketed by Bayer HealthCare Pharmaceuticals ... hepatobiliary phase and thus has different pharmacokinetic and pharmacodynamic properties compared to …

Dabigatran

Dabigatran is the active form of the orally bioavailable prodrug dabigatran etexilate.
Approved
Investigational
Matched Iupac: … 3-[1-(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-1,3-benzodiazol-5-yl)-N-(pyridin-2-yl)formamido …
Matched Description: … Dabigatran is the active form of the orally bioavailable prodrug [dabigatran etexilate]. …

Rabeprazole

Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Approved
Investigational
Matched Description: … and stimulated gastric acid secretion. ... It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form ... Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinflammatory and Antirheumatic Products ... rabeprazole, amoxicillin and metronidazole ... rabeprazole, amoxicillin and clarithromycin ... Topical Products for Joint and Muscular Pain …

Tegaserod

Novartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C).[L5918,F4229] It was, however, voluntarily withdrawn from widespread use in the US market in 2007 after concerns arose over the possibility that tegaserod could potentially cause...
Approved
Investigational
Withdrawn
Matched Description: … the unique mechanism of action of acting on serotonin-4 (5-HT(4)) receptors in smooth muscle cells and ... the gastrointestinal wall to facilitate actions like esophageal relaxation, peristaltic gut movement, and ... re-approval' of tegaserod for treatment of IBS-C specifically in female patients less than 65 years of age and …
Matched Categories: … Alimentary Tract and Metabolism …
Displaying drugs 326 - 350 of 15161 in total