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Displaying drugs 51 - 75 of 332 in total

Pheneticillin

Pheneticillin (or phenethicillin) is a penicillin antibiotic which is approved for use internationally.
Approved
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenoxypropanamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic ... acid …
Matched Salts cas: … 132-93-4 …
Matched Salts name: … Pheneticillin potassium …

Docusate

Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation . Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass . Docusate can be orally or rectally administered. Docusate is on the World...
Approved
Matched Iupac: … 1,4-bis[(2-ethylhexyl)oxy]-1,4-dioxobutane-2-sulfonic acid …
Matched Salts cas: … 128-49-4 ... 577-11-7 ... 7491-09-0 …
Matched Mixtures name: … PNV Ferrous Fumarate Docusate Folic Acid ... VemaVite-PRx 2 with Fish-Based DHA ... Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA …
Matched Salts name: … Docusate potassium …
Matched Products: … Doxate-S Cap 100mg USP ... Jamp Docusate S Oblong …

Loperamide

Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid that is structurally similar to opiate receptor agonists such as diphenoxylate and haloperidol. Due to...
Approved
Matched Iupac: … 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide …
Matched Salts cas: … 34552-83-5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2B6 Substrates ... Cytochrome P-450 CYP3A Inhibitors …
Matched Products: … DIATROL SYRUP 1 mg/5 ml ... Anti-Diarrheal 24/7 for Life by 7-Eleven ... 7 Select Anti Diarrheal …

Fluoxymesterone

An anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.
Approved
Illicit
Matched Synonyms: … 11β,17β-Dihydroxy-9α-fluoro-17α-methyl-4-androster-3-one ... 9-Fluoro-11β,17β-dihydroxy-17-methylandrost-4-en-3-one …
Matched Iupac: … dihydroxy-1,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7- …
Matched Categories: … 3-Oxoandrosten (4) Derivatives …

Patiromer

Patiromer is a powder for suspension in water for oral administration, approved in the U.S. as Veltassa in October, 2015. Patiromer is supplied as patiromer sorbitex calcium which consists of the active moiety, patiromer, a non-absorbed potassium-binding polymer, and a calcium-sorbitol counterion. Each gram of patiromer is equivalent to a...
Approved
Investigational
Matched Description: … supplied as patiromer sorbitex calcium which consists of the active moiety, patiromer, a non-absorbed potassium-binding ... The chemical name for patiromer sorbitex calcium is cross-linked polymer of calcium 2-fluoroprop-2-enoate ... Each gram of patiromer is equivalent to a nominal amount of 2 grams of patiromer sorbitex calcium. …
Matched Categories: … Potassium Binder ... Potassium-removing Agents ... Potassium Ion Binding Activity …

Calcium glycerophosphate

Calcium glycerophosphate is a DB01373 salt of glycerophosphoric acid that forms a white, fine, slightly hygroscopic powder. The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source...
Approved
Matched Synonyms: … β-glycerophosphoric acid calcium salt …
Matched Iupac: … calcium 2-(phosphonooxy)propane-1,3-diol …
Matched Description: … Calcium glycerophosphate is a [DB01373] salt of glycerophosphoric acid that forms a white, fine, slightly …

Metamizole

Metamizole (dipyrone) is a pyrazolone derivative that belongs to the group of nonacid nonopioids. It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability. Metamizole was formerly marketed in the US as Dimethone tablets and injection, Protemp oral liquid, and other drug products, and was withdrawn due to...
Approved
Investigational
Withdrawn
Matched Iupac: … [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonic acid …
Matched Salts cas: … 68-89-3 ... 6150-97-6 ... 5907-38-0 …
Matched Mixtures name: … DIPIRONA 2.5 G + HIOSCINA 20 MG/5 ML SOLUCION INYECTABLE ... N-BUTIL BROMURO DE HIOSCINA20MG + DIPIRONA 2500 MG/5 ML ... DIPIRONA 2.5 G + HIOSCINA 20 MG/5 ML SOLUCION INYECTABLE …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP2B6 Inducers ... Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP3A4 Inducers ... Cytochrome P-450 Enzyme Inducers …
Matched Products: … PRECIDONA-S ... DEVALJİN 1 G/2 ML I.M./I.V. ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL 5 AMPUL ... METAMIZOL 1 G/2 ML IM/IV ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 5 ADET …

Pemirolast

Pemirolast potassium is a slightly yellow powder that is soluble in water. It is a mast cell stabilizer that acts as an antiallergic agent. As an ophthalmic aqueous sterile solution, pemirolast is used for the prevention of itching of the eyes caused by allergies such as hay fever, and allergic...
Approved
Investigational
Matched Iupac: … 9-methyl-3-(2H-1,2,3,4-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one …
Matched Description: … Pemirolast potassium is a slightly yellow powder that is soluble in water. …
Matched Salts name: … Pemirolast potassium …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Somatotropin

Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood...
Approved
Investigational
Matched Description: … acid residues with a molecular weight of 22 kDa. ... Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone that contains 191 amino …
Matched Categories: … Amino Acids, Peptides, and Proteins ... P-glycoprotein substrates ... Cytochrome P-450 CYP1A2 Inducers ... Cytochrome P-450 Enzyme Inducers ... Cytochrome P-450 CYP2C19 Inhibitors …
Matched Products: … SAIZEN 4 IU FLAKON, 1 ADET ... GROWTROPINAQ 16 U /2 ML INYECTABLE ... HUMATROPE 18 IU (6 MG) LIYOFILIZE TOZ ICEREN KARTUS, 1 ADET …

Magnesium

Magnesium is classified as an alkaline earth metal and has 2 hydration shells. The element can be found in abundance in the hydrosphere and in mineral salts such as dolomite and magnesium carbonate. Common dietary sources of magnesium include nuts (cashews, peanuts, almonds), beans, bananas, apples, carrots, broccoli, and leafy...
Approved
Experimental
Investigational
Matched Description: … Magnesium is classified as an alkaline earth metal and has 2 hydration shells. …
Matched Mixtures name: … Cal/mag 2:1 With D ... Acti-cal/mag 2:1 + Zinc and D Caplet ... Chelated Cal-mag(2:1)with Zn Vit.c and D …
Matched Products: … Kordel’s Magnesium Amino Acid Chelate 750 Capsules ... MG 5 LONGORAL ... Emgecard 5 mmol - Granulat …

Prucalopride

Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties. The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies. Prucalopride was developed by Shire Development LLC...
Approved
Matched Iupac: … 4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide …
Matched Description: … is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5- ... developed by Shire Development LLC and approved for use in Europe in 2009,[A40250] in Canada on December 7, …
Matched Salts cas: … 179474-80-7 ... 179474-85-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Serotonin 5-HT4 Receptor Agonists ... Serotonin-4 Receptor Agonist ... Serotonin 4 Receptor Agonists ... Cytochrome P-450 Substrates …
Matched Products: … Resolor Film-coated Tablet 2 mg ... Resolor Film-coated Tablet 1 mg ... RESOLOR ® TABLETAS RECUBIERTAS DE 2 MG …

Sodium fluoride

Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as Fluoride ion F-18. Sodium fluoride's benefits on dental health were first observed in the 1930s, when individuals in communities with fluoridated...
Approved
Matched Mixtures name: … PREVENT 2 EN 1 ... DOCTRUST ONE S Tooth ... 4 Pack …
Matched Products: … Crest Complete Plus 3 in 1 ... Amino Acid Fragrancemouthwash Dawn ... Amino Acid Fragrancemouthwash Blossom …

Amifampridine

Amifampridine, or 3,4-diaminopyridine (3,4-DAP), is a quaternary ammonium compound that blocks presynaptic potassium channels, and subsequently prolongs the action potential and increases presynaptic calcium concentrations . It was first discovered in Scotland in the 1970s and its clinical effectiveness for neuromuscular disorders, including Lambert–Eaton myasthenic syndrome (LEMS), has been investigated...
Approved
Investigational
Matched Description: … Amifampridine, or 3,4-diaminopyridine (3,4-DAP), is a quaternary ammonium compound that blocks presynaptic potassium ... Patients with LEMS develop serum antibodies against presynaptic P/Q-type voltage-gated calcium channels …
Matched Salts cas: … 446254-47-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Potassium Channel Blockers …

Fludrocortisone

Fludrocortisone is a synthetic mineralocorticoid used in conjunction with hydrocortisone to replace missing endogenous corticosteroids in patients with adrenal insufficiency.[A187169,A187187] It is functionally similar to aldosterone, the body's primary endogenous mineralocorticoid, and is structurally analogous to cortisol, differing only by a fluorine atom at the 9-position of the steroid structure...
Approved
Investigational
Matched Iupac: … (1R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH ... ,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one …
Matched Salts cas: … 514-36-3 …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates …

Homatropine methylbromide

Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be...
Approved
Matched Synonyms: … 3-alpha-Hydroxy-8-methyl-1-alpha-H,5-alpha-H-tropanium bromide mandelate …
Matched Iupac: … 3-[(2-hydroxy-2-phenylacetyl)oxy]-8,8-dimethyl-8-azabicyclo[3.2.1]octan-8-ium bromide …

Digoxin

Digoxin is one of the oldest cardiovascular medications used today. It is a common agent used to manage atrial fibrillation and the symptoms of heart failure. Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954. This drug originates from the foxglove plant, also...
Approved
Matched Iupac: … 4-[(1R,3aS,3bR,5aR,7S,9aS,9bS,11R,11aS)-7-{[(2R,4S,5S,6R)-5-{[(2S,4S,5S,6R)-5-{[(2S,4S,5S,6R)-4,5-dihydroxy ... -9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2,5-dihydrofuran-2-one ... -6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-3a,11-dihydroxy …
Matched Categories: … P-glycoprotein inducers ... P-glycoprotein inhibitors ... P-glycoprotein substrates ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Products: … DIGOXIN-ASSOS 0,5 MG /2 ML IV ENJEKSİYON İÇEREN AMPUL, 5 ADET ... LANOXIN INJECTION 0.5 mg/2 ml …

Pinacidil

Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood pressure. This drug has been discontinued by the FDA.
Approved
Matched Iupac: … (Z)-N'-cyano-N-(3,3-dimethylbutan-2-yl)-N''-(pyridin-4-yl)guanidine …
Matched Description: … Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to …
Matched Categories: … Potassium Channel Opener ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates …

D-glucose

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Investigational
Vet approved
Matched Iupac: … (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal …
Matched Salts cas: … 77938-63-7 …
Matched Mixtures name: … Isolyte S in Dextrose ... Prismasol Bgk2/0 ... Prismasol B22gk4/0 …
Matched Products: … DEXTROSE INJ 5% BP (1000ML P/C) ... %5 DEKSTROZ SUDAKI ÇÖZELTISI BFS ,150 ML, 1 ŞIŞE, SETLI ... %5 DEKSTROZ SUDAKI ÇÖZELTISI BFS ,250 ML, 1 ŞIŞE, SETLI …

Glymidine

Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and increasing the sensitivity of peripheral tissues to insulin. The mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta...
Approved
Investigational
Matched Iupac: … N-[5-(2-methoxyethoxy)pyrimidin-2-yl]benzenesulfonamide …
Matched Description: … It is used for the concomitant use with insulin for the treatment of noninsulin-dependent (type 2) diabetes ... , reducing potassium conductance and causing depolarization of the membrane. ... Glycodiazine likely binds to ATP-sensitive potassium channel receptors on the pancreatic cell surface …

Polythiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)
Approved
Matched Iupac: … 6-chloro-2-methyl-1,1-dioxo-3-{[(2,2,2-trifluoroethyl)sulfanyl]methyl}-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine ... -7-sulfonamide …
Matched Mixtures name: … Renese-R …
Matched Categories: … polythiazide and potassium ... Heterocyclic Compounds, 2-Ring …

Rabeprazole

Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Approved
Investigational
Matched Iupac: … 2-{[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methanesulfinyl}-1H-1,3-benzodiazole …
Matched Description: … It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form ... H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid …
Matched Salts cas: … 117976-90-6 …
Matched Categories: … Carboxylic Acids ... Heterocyclic Compounds, 1-Ring ... Acid Reducers ... 2-Pyridinylmethylsulfinylbenzimidazoles ... Heterocyclic Compounds, 2-Ring …
Matched Products: … Raberprazole Sodium D/r …

Plasma protein fraction (human)

The plasma protein fraction human (PPFh) is defined as a sterile solution of proteins composed mainly of albumin and globulin derived from human plasma. It is already reviewed under the category of biologics by the FDA where the processing, required tests, requirements and labeling are incorporated. This biologic should come...
Approved
Matched Description: … It is also stated that no more than 1% of the total protein should be gamma globulin. ... The composition of PPFh should be 5% of protein from which 83% should consist of albumin and no more ... stabilized with sodium caprylate and acetyltryptophan and it contains some electrolytes such as sodium, potassium …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … SANDOGLOBULINA 6 G ... Octaplas SD Blutgruppe 0 zur Infusion ... PLASMANATE INJECTION 5% …

Rocuronium

Rocuronium (rapid onset-curonium) is a desacetoxy analogue of vecuronium with a more rapid onset of action. It is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Introduced in 1994, rocuronium has...
Approved
Matched Iupac: … 1-[(1R,2S,3aS,3bR,5aS,7S,8S,9aS,9bS,11aS)-1-(acetyloxy)-7-hydroxy-9a,11a-dimethyl-8-(morpholin-4-yl)- ... hexadecahydro-1H-cyclopenta[a]phenanthren-2-yl]-1-(prop-2-en-1-yl)pyrrolidin-1-ium …
Matched Products: … ROCUREX(R)100MG ... JECRON 50 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... JECRON 50 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 ADET AMPUL …

Cyclopenthiazide

Cyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients . It is a positive allosteric modulator at AMPA-A receptors .
Approved
Matched Iupac: … 6-chloro-3-(cyclopentylmethyl)-1,1-dioxo-3,4-dihydro-2H-1λ⁶,2,4-benzothiadiazine-7-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... cyclopenthiazide and potassium ... cyclopenthiazide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …

Prednisolone acetate

Prednisolone acetate is a prednisolone molecule bound to an acetate functional group by an ester bond. Prednisolone acetate was granted FDA approval in 1955.
Approved
Vet approved
Matched Iupac: … 2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH ... ,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate …
Matched Mixtures name: … CONJUNTIN-S® LIQUIFILM® SUSPENSION OFTALMICA ESTERIL ... SUPRENIL STERIL OFTALMIK SUSPANSIYON 5 ML ... BLEPHAMIDE % 0,2 + % 10 GÖZ DAMLASI, SÜSPANSİYON, 5 ML …
Matched Categories: … P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP3A4 Inducers ... Cytochrome P-450 CYP3A Substrates …
Matched Products: … PRED FORTE % 1 GÖZ DAMLASI, SÜSPANSİYON, 5 ML ... Ak Tate Oph Sus 1% ... Diopred Suspension 1% …
Displaying drugs 51 - 75 of 332 in total