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Displaying drugs 176 - 200 of 14844 in total

Gadobenic acid

Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity....
Approved
Investigational
Matched Description: … gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of ... [A263166] As gadobenate dimeglumine is specifically taken up by hepatocytes and excreted through the ... other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and …
Matched Salts cas: … 127000-20-8 …
Matched Categories: … Diagnostic Uses of Chemicals …
Matched Products: … MULTIHANCE INJECTION 20 ML ... MULTIHANCE TEK DOZLUK IV ENJEKSIYONLUK COZELTI ICEREN FLAKON, 20 ML …

Larotrectinib

Larotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays an important role in tumor cell growth and survival. Upon administration, larotrectinib binds to Trk, thereby preventing neurotrophin-Trk interaction and...
Approved
Investigational
Matched Description: … Trk activation, which results in both the induction of cellular apoptosis and the inhibition of cell ... kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays an important ... role in tumor cell growth and survival. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … VITRAKVI 20 MG/ML ORAL ÇÖZELTİ, 2x50 ML …

Clavulanic acid

Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections. Clavulanic acid is derived from the organism Streptomyces clavuligerus. When it is combined with amoxicillin, clavulanic acid is...
Approved
Vet approved
Matched Description: … antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of …
Matched Mixtures name: … KLAVUNAT BID 200/28 MG 70 ML ORAL SUSPANSIYON ... KLAVUNAT BID 200/28 MG 100 ML ORAL SUSPANSIYON ... CROXILEX-BID 200/28 ORAL SUSPANSIYON ICIN KURU TOZ, 70 ML …

Quinidine barbiturate

The administration of quinidine derivatives helps to observe various skin and mucosal reactions. A papulopurpuric eruption in a patient (without thrombopenia) can be developed who is taking quinidine phenylethyl barbiturate intermittently and at reintroduction.(PMID: 9739909)
Approved
Matched Description: … The administration of quinidine derivatives helps to observe various skin and mucosal reactions. ... without thrombopenia) can be developed who is taking quinidine phenylethyl barbiturate intermittently and …
Matched Products: … NATISEDINE 100 MG TABLET, 20 ADET …

Methenamine

Methenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).
Approved
Vet approved
Matched Description: … which is the hippuric acid salt of methenamine). ... In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate …
Matched Mixtures name: … Non Toxic Disinfectant ... Methenamine and Sodium Salicylate ... Methenamine and Sodium Salicylate (nsaid) …
Matched Products: … HIPPURIN 1 GR FILM TABLET, 28 ADET …

Ketorolac

Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. It's analgesic properties make it a useful pain management tool across many settings including postoperative pain, rheumatoid arthritis, osteoarthritis, menstrual disorders, headaches, spinal and soft tissue pain,...
Approved
Matched Description: … Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral ... [L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making ... soft tissue pain, and ankylosing spondylitis. …
Matched Categories: … Antiinflammatory and Antirheumatic Products, Non-Steroids ... Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) ... Mydriatics and Cycloplegics ... phenylephrine and ketorolac ... Analgesics, Non-Narcotic …
Matched Products: … KERADOL (R) TABLETAS 20 MG ... SANTOR 10 MG FİLM TABLET, 20 TABLET ... İEROLAK 10 MG FİLM TABLET, 20 ADET …

Methylcellulose

Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3,...
Approved
Matched Description: … and emulsifier for foodstuffs and cosmetics. ... The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number ... Like cellulose, it is not digestible, not toxic, and not allergenic …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Fiber Laxative 188 …

Quinidine

Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Description: … Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species ... [A38016] Due to its side effects and increased risk of mortality, the use of quinidine was reduced over ... However, it continues to be used in the treatment of Brugada syndrome, short QT syndrome and idiopathic …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Quinine and stereoisomer …
Matched Products: … QUINICARDINE 200 MG KOMPRIME, 20 ADET …

Diflunisal

Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the...
Approved
Investigational
Matched Description: … Diflunisal is used to relieve pain accompanied with inflammation and in the symptomatic treatment of ... rheumatoid arthritis and osteoarthritis. ... Though its mechanism of action has not been clearly established, most of its actions appear to be associated …
Matched Categories: … Salicylic Acid and Derivatives ... Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) ... Analgesics, Non-Narcotic ... Non COX-2 selective NSAIDS ... Anti-Inflammatory Agents, Non-Steroidal …
Matched Products: … DOLPHIN 250 MG FILM TABLET, 20 TABLET …

Propofol

Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness,...
Approved
Investigational
Vet approved
Matched Description: … status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries ... Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia ... using a combination of medications. …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … CRIXOFOL 10MG/1MLAMPOLLA POR 20 ML ... RAPIFOL INYECCION 20 ML (PROPOFOL 10 MG/ML) ... PROPOFOL % 1 FRESENIUS 10 GR 20 ML AMPUL, 5 ADET …

Verapamil

Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs...
Approved
Matched Description: … [A188514] It is a member of the non-dihydropyridine class of calcium channel blockers, which includes ... , each of which is pharmacologically distinct - the S-enantiomer carries approximately 20-fold greater ... [L8791] Verapamil is administered as a racemic mixture containing equal amounts of the S- and R-enantiomer …
Matched Mixtures name: … TARKA 180/2 FILM TABLET, 28 ADET ... VERACOMB MR 180/2 MG KAPSÜL, 28 ADET ... VERACOMB MR 240/4 MG KAPSÜL, 28 ADET …
Matched Categories: … Verapamil and analogues ... trandolapril and verapamil ... ACE Inhibitors and Calcium Channel Blockers …

Pantothenic acid

Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats....
Approved
Nutraceutical
Vet approved
Matched Description: … (L) form may antagonize the effects of the dextrorotatory isomer. ... Small quantities of pantothenic acid are found in nearly every food, with high amounts in whole-grain ... Only the dextrorotatory (D) isomer of pantothenic acid possesses biological activity. while the levorotatory …
Matched Mixtures name: … BECOVIGEN DRAJE, 20 ADET ... BEMIKS C FILM KAPLI TABLET, 28 ADET ... Herbs of Gold B Complex Plus Softgel …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …

Fidaxomicin

Fidaxomicin is a novel macrolide antibiotic used in the treatment of diarrhea caused by Clostridioides (formerly Clostridium) difficile in adult and pediatric patients over the age of 6 months. Fidaxomicin is a naturally-occurring 18-member macrocycle derived from fermentation. Because fidaxomicin contains an 18-membered lactone ring in its structure, it is...
Approved
Matched Description: … _ (formerly _Clostridium_) _difficile_ in adult and pediatric patients over the age of 6 months. ... [A190492] The antibacterial activity of fidaxomicin is distinct from macrolides and rifamycins, as the ... bactericidal activity is time-dependent, and not concentration-dependent. …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … DİFİCLİR 200 MG FİLM KAPLI TABLET, 20 ADET …

Terconazole

Terconazole is an anti-fungal drug that is mainly used to treat vaginal yeast infections (or vaginal candidiasis). It is classified as a triazole ketal derivative. Terconazole was initially approved by the FDA in 1987.[FDA label] This drug is available in cream and suppository forms and both have demonstrated high levels...
Approved
Matched Description: … of safety, efficacy, and tolerability in clinical trials. ... [FDA label] This drug is available in cream and suppository forms and both have demonstrated high levels ... [A178093]Due to the existence of 2 stereocentres, there are 4 possible stereoisomers for terconazole. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Sodium aurothiomalate

Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Gold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold Sodium Thiomalate per mL. It is most effective in active progressive rheumatoid arthritis and of little or no value in...
Approved
Investigational
Matched Description: … It is most effective in active progressive rheumatoid arthritis and of little or no value in the presence ... of extensive deformities or in the treatment of other forms of arthritis. ... Gold Sodium Thiomalate is supplied as a solution for intramuscular injection containing 50 mg of Gold …
Matched Categories: … Antiinflammatory and Antirheumatic Products …
Matched Products: … MYOCRISIN INJECTION 20 MG (4% W/V) …

Zinc gluconate

Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for...
Approved
Vet approved
Matched Description: … of common colds and with decreased symptom severity. ... salts (oral rehydration solution), may reduce both the duration and severity of diarrheal episodes for ... It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration …
Matched Mixtures name: … One A Day With Non-medicinal Echinacea ... Multivitamin and Mineral ... Zinc and Algin Tab Nu Life …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Alimentary Tract and Metabolism …

Nafcillin

A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic drug. It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections caused by strains that are resistant to other penicillins, except those caused by MRSA. It may be used as a first-line therapy in...
Approved
Investigational
Matched Description: … It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections …
Matched Categories: … combinations of penicillins …

Nomifensine

Nomifensine, formerly marketed as Merital capsules, was associated with an increased incidence of hemolytic anemia. The approved application holder removed Merital capsules from the market on January 23, 1986. FDA published a notice of its determination that Merital capsules were removed from the market for safety reasons (see the Federal...
Approved
Withdrawn
Matched Description: … Approval of the NDA for Merital capsules was withdrawn on March 20, 1992 (see the Federal Register of ... Also withdrawn from the Canadian and UK markets. ... March 20, 1992 (57 FR 9729)). …

Indigotindisulfonic acid

Indigotindisulfonic acid is a blue-colored dye with a variety of uses.[A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2. This compound is an acid-base indicator and is used in the production of food colorants and pH tests. Indigotindisulfonic acid is used in...
Approved
Investigational
Matched Description: … This compound is an acid-base indicator and is used in the production of food colorants and pH tests. ... system, and to assist in specific surgical procedures such as cystourethroscopy. ... Indigotindisulfonic acid is a blue-colored dye with a variety of uses. …
Matched Categories: … Tests for Renal Function and Ureteral Injuries …
Matched Products: … INDIGO CARMINE INJECTION 20 mg/5 ml …

Gadoversetamide

Gadoversetamide, marketed under the trade name OptiMARK, is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver.
Approved
Investigational
Matched Description: … the brain, spine and liver. ... gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of …
Matched Categories: … Diagnostic Uses of Chemicals …
Matched Products: … ICEREN FLAKON, 20 ML ... ICIN COZELTI ICEREN KUL.HAZIR SIRINGA, 20 ML …

Olopatadine

Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Description: … An ophthalmic solution of olopatadine was approved by the FDA and European Union for the treatment of ... seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. ... inflammatory and allergic reactions. …
Matched Categories: … Decongestants and Antiallergics ... Histamine H1 Antagonists, Non-Sedating …
Matched Products: … Eye Allergy Itch and Redness Relief ... Eye Allergy Itch and Redness Relief Twice Daily Relief …

Olanzapine

Olanzapine is a thienobenzodiazepine classified as an atypical or second-generation antipsychotic agent. The second-generation antipsychotics were introduced in the 90s and quickly gained traction due to their impressive efficacy, reduced risk for extrapyramidal side effects and reduced susceptibility to drug-drug interactions. Olanzapine very closely resembles clozapine and only differs by...
Approved
Investigational
Matched Description: … and the absence of a chloride moiety. ... [A176996] The second-generation antipsychotics were introduced in the 90s and quickly gained traction ... [T554] It was discovered by scientists at Eli Lilly and approved to be marketed in the US in 1996. …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Categories: … olanzapine and samidorphan ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome ... Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … ZOLAPINE 20 MG TABLET, 28 ADET ... APZET 20 MG FILM TABLET, 28 ADET ... ELYNZA 20 MG FILM TABLET, 28 ADET …

Prednisone

A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. Prednisone was granted FDA approval on 21 February 1955.
Approved
Vet approved
Matched Description: … [A187463] It is biologically inert and converted to [prednisolone] in the liver. …
Matched Categories: … Alimentary Tract and Metabolism ... Prednisolone and Prodrugs ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … PredniSONE Tablets, USP, 20 mg …

Insulin aspart

Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … Without treatment or improvement in non-pharmacological measures such as diet and exercise to lower blood ... Use of basal and bolus insulin together is intended to mimic the pancreas' production of endogenous insulin ... is a slowly progressing metabolic disorder caused by a combination of genetic and lifestyle factors …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and insulin aspart ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … .Insulin Aspart Protamine and Insulin Aspart ... Insulin Aspart Protamine and Insulin Aspart Mix 70/30 …

Flupentixol

Flupentixol is an antipsychotic drug of the thioxanthene group. It exists in two geometric isomers, the trans(E) and pharmacologically active cis(Z) forms. Flupentixol decanoate is one of the active ingredients found in injectable drug formulations: it is produced by esterification of cis(Z)‐flupentixol with decanoic acid. Flupentixol is an antagonist of...
Approved
Investigational
Withdrawn
Matched Description: … [A229083] Flupentixol is an antagonist of both D1 and D2 dopamine receptors. ... , and asthenia. ... signs of anxiety. …
Matched Mixtures name: … DORMIR TABLET, 20 ADET …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … FLUANXOL DEPOT INJECTION 20 mg/ml ... Fluanxol Depot 20 mg - Injektionslösung …
Displaying drugs 176 - 200 of 14844 in total