Displaying drugs 176 - 200 of 10664 in total
Lisocabtagene maraleucel
Lisocabtagene maraleucel is a chimeric antigen receptor (CAR) T-cell therapy, similar to brexucabtagene autoleucel and axicabtagene ciloleucel.[A228493,L31588] Lisocabtagene maraleucel is a genetically modified autologous T-cell therapy that targets CD19, the B-lymphocyte surface antigen B4. CAR T-cell therapy has changed the treatment of B-cell lymphomas, significantly increasing survival rates over standard...
Approved
Matched Description: … an overall increase in quality of life over a 1 year period. ... [A228493] However, data on the efficacy of CAR T-cell therapies on less severe forms of B-cell lymphoma ... [L31588]
CAR T-cell therapy has changed the treatment of B-cell lymphomas, significantly increasing …
Matched Categories: … Antineoplastic cell and gene therapy …
Matched Categories: … Antineoplastic cell and gene therapy …
Artemether
Artemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and may be used to treat infections caused by P. falciparum and unidentified Plasmodium species, including...
Approved
Matched Description: … This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. ... It is administered in combination with lumefantrine for improved efficacy. ... caused by P. falciparum and unidentified Plasmodium species, including infections acquired in …
Norfloxacin
A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Approved
Matched Synonyms: … 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsäure ... 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Influenza B virus B/Victoria/705/2018 BVR-11 antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Matched Mixtures name: … FLUAD Injektionssuspension in einer Fertigspritze ... Sandovac Injektionssuspension in einer Fertigspritze …
Matched Mixtures name: … FLUAD Injektionssuspension in einer Fertigspritze ... Sandovac Injektionssuspension in einer Fertigspritze …
Iron
A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron...
Approved
Matched International brands: … Ed-In-Sol ... Fer-In-Sol …
Matched Description: … Depletion of iron stores may result in iron-deficiency anemia. ... Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms ... It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme …
Matched Products: … FER-IN-SOL …
Matched Description: … Depletion of iron stores may result in iron-deficiency anemia. ... Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms ... It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme …
Matched Products: … FER-IN-SOL …
Cobicistat
Cobicistat, marketed under the name Tybost (formerly GS-9350), indicated for treating infection with human immunodeficiency virus (HIV). Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered agents that are metabolized...
Approved
Matched Description: … once daily dosing regimen) in combination with other antiretroviral agents in the treatment of HIV-1 ... More specifically, cobicistat is indicated to increase systemic exposure of atazanavir or darunavir ( ... enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections ... Metabolic Side Effects of Drugs and Substances …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections ... Metabolic Side Effects of Drugs and Substances …
Atorvastatin
Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,...
Approved
Matched Iupac: … (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic …
Matched Description: … wide use of this medication in North America. ... [A181087, A181406] The increasing use of this class of drugs is largely attributed to the rise in cardiovascular ... Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. …
Matched Description: … wide use of this medication in North America. ... [A181087, A181406] The increasing use of this class of drugs is largely attributed to the rise in cardiovascular ... Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. …
Beclomethasone dipropionate
Beclomethasone dipropionate is a second-generation synthetic corticosteroid and diester of beclomethasone, which is structurally similar to dexamethasone. It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP) which acts on the glucocorticoid receptor to mediates its therapeutic action. Beclomethasone dipropionate itself posesses weak glucocorticoid receptor binding affinity and is...
Approved
Investigational
Matched Iupac: … 2-[(1R,2S,3aS,3bS,9aS,9bR,10S,11aS)-9b-chloro-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1-(propanoyloxy)-1H …
Matched Description: … Beclomethasone dipropionate became first available in a pressurized metered-dose inhaler in 1972 and ... [L6871] It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP)[A179839] which ... Beclomethasone dipropionate is a second-generation[A179842] synthetic corticosteroid and diester of beclomethasone …
Matched Description: … Beclomethasone dipropionate became first available in a pressurized metered-dose inhaler in 1972 and ... [L6871] It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP)[A179839] which ... Beclomethasone dipropionate is a second-generation[A179842] synthetic corticosteroid and diester of beclomethasone …
Threonine
An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.
Approved
Nutraceutical
Matched Description: … It is found in eggs, milk, gelatin, and other proteins. ... An essential amino acid occurring naturally in the L-form, which is the active form. …
Matched Mixtures name: … Aminosyn II 7% M In 10% Dextrose(dual Chamber) ... Numeta G 13 % E Emulsion zur Infusion ... Aminosyn 7% …
Matched Mixtures name: … Aminosyn II 7% M In 10% Dextrose(dual Chamber) ... Numeta G 13 % E Emulsion zur Infusion ... Aminosyn 7% …
Glycine
A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
Approved
Nutraceutical
Vet approved
Matched Description: … It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. …
Matched Mixtures name: … Aminosyn II 7% M In 10% Dextrose(dual Chamber) ... Numeta G 13 % E Emulsion zur Infusion ... Aminosyn 7% …
Matched Mixtures name: … Aminosyn II 7% M In 10% Dextrose(dual Chamber) ... Numeta G 13 % E Emulsion zur Infusion ... Aminosyn 7% …
Tryptophan
An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit...
Approved
Nutraceutical
Withdrawn
Matched Description: … It is a precursor of indole alkaloids in plants. ... It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). ... An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults …
Matched Mixtures name: … Aminosyn II 7% M In 10% Dextrose(dual Chamber) ... Numeta G 13 % E Emulsion zur Infusion ... Aminosyn 7% …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Mixtures name: … Aminosyn II 7% M In 10% Dextrose(dual Chamber) ... Numeta G 13 % E Emulsion zur Infusion ... Aminosyn 7% …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Lumacaftor
Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Description: … Mutations in the CFTR gene result in altered production, misfolding, or function of the CFTR protein ... gene for the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, a transmembrane ion ... in impaired production of the CFTR protein, thereby causing a significant reduction in the amount of …
Pemigatinib
Pemigatinib is a small molecule kinase inhibitor with antitumour activity. It works by inhibiting fibroblast growth factor receptors (FGFRs), which are receptor tyrosine kinases that activate signalling pathways in tumour cells. FGFRs gained attention as potential therapeutic targets in selected cancers, as FGFR gene alterations were observed in a wide...
Approved
Investigational
Matched Iupac: … 11-(2,6-difluoro-3,5-dimethoxyphenyl)-13-ethyl-4-[(morpholin-4-yl)methyl]-5,7,11,13-tetraazatricyclo[ …
Matched Description: … This malignancy accounts for 15% to 20% of primary hepatobiliary malignancies, which account for 13% ... [A193719] FGFRs gained attention as potential therapeutic targets in selected cancers, as FGFR gene alterations ... exhibited gene rearrangements resulting in oncogenic fibroblast growth factor 2 (FGFR2) fusion proteins …
Matched Description: … This malignancy accounts for 15% to 20% of primary hepatobiliary malignancies, which account for 13% ... [A193719] FGFRs gained attention as potential therapeutic targets in selected cancers, as FGFR gene alterations ... exhibited gene rearrangements resulting in oncogenic fibroblast growth factor 2 (FGFR2) fusion proteins …
Isopropyl alcohol
An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
Approved
Investigational
Matched Description: … It is used in the manufacture of acetone and its derivatives and as a solvent. ... An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. …
Matched Mixtures name: … BRAUNODERM (IN 250ML AND 1000ML PLASTIC) ... Point Of Care L2 ... Point Of Care L5 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Clean Hands 24/7 ... The Essence of Eva ... Coghlans Survival In A Can …
Matched Mixtures name: … BRAUNODERM (IN 250ML AND 1000ML PLASTIC) ... Point Of Care L2 ... Point Of Care L5 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Clean Hands 24/7 ... The Essence of Eva ... Coghlans Survival In A Can …
Influenza A virus A/Uruguay/716/2007(H3N2) antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Selenium Sulfide
Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea. Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent...
Approved
Matched Description: … Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic ... cells in seborrhea. ... Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative …
Matched Products: … Selsun Blue 2-in-1 ... Selsun Blue, 2-IN-1 …
Matched Products: … Selsun Blue 2-in-1 ... Selsun Blue, 2-IN-1 …
Poa pratensis pollen
Poa pratensis pollen is the pollen of the Poa pratensis plant. Poa pratensis pollen is mainly used in allergenic testing.
Approved
Matched Description: … Poa pratensis pollen is mainly used in allergenic testing. ... Poa pratensis pollen is the pollen of the Poa pratensis plant. …
Matched Mixtures name: … Mix Of 7 Standardized Grass Pollen ... 7 Grass Mix ... 7 Grass Mix …
Matched Mixtures name: … Mix Of 7 Standardized Grass Pollen ... 7 Grass Mix ... 7 Grass Mix …
Phleum pratense pollen
Phleum pratense pollen allergenic extract is used in allergenic testing.
Approved
Investigational
Matched Description: … Phleum pratense pollen allergenic extract is used in allergenic testing. …
Matched Mixtures name: … Mix Of 7 Standardized Grass Pollen ... 7 Grass Mix ... 7 Grass Mix …
Matched Mixtures name: … Mix Of 7 Standardized Grass Pollen ... 7 Grass Mix ... 7 Grass Mix …
Lysine
Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as...
Approved
Nutraceutical
Matched Description: … O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain ... Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl ... The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. …
Matched Mixtures name: … Aminosyn II 7% M In 10% Dextrose(dual Chamber) ... Numeta G 13 % E Emulsion zur Infusion ... Aminosyn 7% …
Matched Mixtures name: … Aminosyn II 7% M In 10% Dextrose(dual Chamber) ... Numeta G 13 % E Emulsion zur Infusion ... Aminosyn 7% …
Glofitamab
Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface antigens found on B- and T-cells, respectively. It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting T-cells directly to the surface of cancerous B-cells.[L45698,A258488]
Glofitamab was approved...
Approved
Investigational
Matched Description: … In June 2023, the FDA approved the use of glofitamab for the treatment of patients with relapsed or refractory ... [L45698,A258488]
Glofitamab was approved by Health Canada in March 2023 for the treatment of certain ... [L45768,A258433] In the context of relapsed or refractory DLBCL, glofitamab provides an alternative treatment …
Pravastatin
Pravastatin is the 6-alpha-hydroxy acid form of mevastatin. Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug. This drug was developed by Sankyo Co. Ltd.; however, the first approved...
Approved
Matched Synonyms: … (+)-(3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(S)-2-methylbutyryl]oxy}-1,2,6,7,8,8a-hexahydro …
Matched Iupac: … (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen …
Matched Description: … Pravastatin is the 6-alpha-hydroxy acid form of [mevastatin]. ... [T303] Pravastatin was firstly approved in 1991 becoming the second available statin in the United States ... The manufacturing process is followed by the hydrolysis of the lactone group and the biological hydroxylation …
Matched Iupac: … (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen …
Matched Description: … Pravastatin is the 6-alpha-hydroxy acid form of [mevastatin]. ... [T303] Pravastatin was firstly approved in 1991 becoming the second available statin in the United States ... The manufacturing process is followed by the hydrolysis of the lactone group and the biological hydroxylation …
Petrolatum
A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Approved
Investigational
Matched Description: … A colloidal system of semisolid hydrocarbons obtained from petroleum. …
Matched Mixtures name: … 7 Select Hemorrhoidal Original Strength ... CARMEX Multi-Symptom 3 in 1 COLD Sore treatment External Analgesic Skin Protectant ... Chapstick 12 Days of Christmas …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Care One Medicated Lip Balm in a Pot …
Matched Mixtures name: … 7 Select Hemorrhoidal Original Strength ... CARMEX Multi-Symptom 3 in 1 COLD Sore treatment External Analgesic Skin Protectant ... Chapstick 12 Days of Christmas …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Care One Medicated Lip Balm in a Pot …
Human Rho(D) immune globulin
Human Rho(D) immune globulin is a medicine given by intramuscular or intravenous injection that is used to prevent the immunological condition known as Rh disease (or hemolytic disease of newborn). Rho (D) immune globulin is available as a sterile, lyophilized or liquid gamma globulin (IgG) fraction containing antibodies to the...
Approved
Investigational
Matched Description: … thrombocytopenic purpura (ITP) in adults. ... injection that is used to prevent the immunological condition known as Rh disease (or hemolytic disease of ... Immune globullin was purified via ion-exchange chromatography method and prepared from pools of human …
Matched Products: … rhophylac 300 microgram/2ml,solution for injection in pre-filled syringe …
Matched Products: … rhophylac 300 microgram/2ml,solution for injection in pre-filled syringe …
Ferrous sulfate anhydrous
Iron deficiency anemia is a large public health concern worldwide, especially in young children, infants, and women of childbearing age. This type of anemia occurs when iron intake, iron stores, and iron loss do not adequately support the formation of erythrocytes, also known as red blood cells. Ferrous sulfate is...
Approved
Matched Description: … [A190528]
Ferrous sulfate is a synthetic agent used in the treatment of iron deficiency. ... It is the gold standard of oral iron therapy in the UK and many other countries.[L2234,L2246] ... , and women of childbearing age. …
Matched Products: … FER IN SOL GOTAS …
Matched Products: … FER IN SOL GOTAS …
Corynebacterium diphtheriae CRM197 protein
Approved
Matched Mixtures name: … Prevenar 13 Suspension For Injection …
Displaying drugs 176 - 200 of 10664 in total