Unlocking Undruggable Targets: Shifting Paradigms in Modern Drug Discovery
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Drugs
Drugs and Targets
Drug Trials
Drug
Drug Name
Drug Description
DB00958
Carboplatin
A alkylating agent used to treat advanced ovarian cancer.
Drug
Drug Name
Target
Type
DB00958
Carboplatin
DNA
target
DB00958
Carboplatin
High affinity copper uptake protein 1
transporter
DB00958
Carboplatin
Probable low affinity copper uptake protein 2
transporter
DB00958
Carboplatin
Xanthine dehydrogenase/oxidase
enzyme
DB00958
Carboplatin
Myeloperoxidase
enzyme
DB00958
Carboplatin
Glutathione S-transferase theta-1
enzyme
DB00958
Carboplatin
Metallothionein-1A
enzyme
DB00958
Carboplatin
Metallothionein-2
enzyme
DB00958
Carboplatin
Superoxide dismutase [Cu-Zn]
enzyme
DB00958
Carboplatin
Glutathione S-transferase P
enzyme
DB00958
Carboplatin
Glutathione S-transferase Mu 1
enzyme
DB00958
Carboplatin
NAD(P)H dehydrogenase [quinone] 1
enzyme
DB00958
Carboplatin
Copper-transporting ATPase 1
transporter
DB00958
Carboplatin
Copper-transporting ATPase 2
transporter
DB00958
Carboplatin
ATP-binding cassette sub-family G member 2
transporter
DB00958
Carboplatin
Canalicular multispecific organic anion transporter 1
transporter
Drug
Drug Name
Phase
Status
Count
DB00062
Albumin human
0
Withdrawn
1
DB11363
Alectinib
0
Withdrawn
1
DB12015
Alpelisib
0
Withdrawn
1
DB01217
Anastrozole
0
Withdrawn
1
DB11595
Atezolizumab
0
Withdrawn
1
DB00112
Bevacizumab
0
Withdrawn
1
DB01101
Capecitabine
0
Withdrawn
1
DB00958
Carboplatin
0
Withdrawn
1
DB05239
Cobimetinib
0
Withdrawn
1
DB11986
Entrectinib
0
Withdrawn
1
DB08871
Eribulin
0
Withdrawn
1
DB00947
Fulvestrant
0
Withdrawn
1
DB06205
Hyaluronidase (human recombinant)
0
Withdrawn
1
DB00762
Irinotecan
0
Withdrawn
1
DB01006
Letrozole
0
Withdrawn
1
DB11793
Niraparib
0
Withdrawn
1
DB09074
Olaparib
0
Withdrawn
1
DB01229
Paclitaxel
0
Withdrawn
1
DB09073
Palbociclib
0
Withdrawn
1
DB06366
Pertuzumab
0
Withdrawn
1
DB00072
Trastuzumab
0
Withdrawn
1
DB05773
Trastuzumab emtansine
0
Withdrawn
1
DB08881
Vemurafenib
0
Withdrawn
1
DB00361
Vinorelbine
0
Withdrawn
1
DB08828
Vismodegib
0
Withdrawn
1
DB11945
Avelumab
1
Active Not Recruiting
1
DB17520
Vimseltinib
1
Active Not Recruiting
1
DB00997
Doxorubicin
1 / 2
Active Not Recruiting
1
DB15769
Envafolimab
1 / 2
Active Not Recruiting
1
DB05668
Palifosfamide
1 / 2
Completed
1
DB09078
Lenvatinib
2
Active Not Recruiting
1
DB09037
Pembrolizumab
2
Active Not Recruiting
1