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Displaying drugs 51 - 75 of 8741 in total
Equine Botulinum Neurotoxin A Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype A. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes A in...
Approved
Experimental
Investigational
Matched Synonyms: … Botulinum Neurotoxin A immune FAB2 (equine) ... BOTULINUM NEUROTOXIN A IMMUNE FAB2, EQUINE …
Matched Name: … Equine Botulinum Neurotoxin A Immune FAB2 …
Matched Description: … Equine Botulinum Neurotoxin A Immune FAB2 is composed of a mixture of immune globulin fragments purified ... from plasma of horses that were previously immunized with botulinum toxin serotype A. ... of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes A
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … Influenza a Virus A/california/7/2009(h1n1)-like Hemagglutinin Antigen (Formaldehyde Inactivated) …
Matched Name: … Influenza A virus A/California/7/2009 (H1N1)-like hemagglutinin antigen (formaldehyde inactivated) …
Matched Description: … A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Approved
Investigational
Matched Synonyms: … N-(p-Aminobenzoyl)glycine ... N-(para-aminobenzoyl)glycine ... N-(p-Aminobenzoyl)aminoacetic acid …
Matched Description: … Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Metamizole (dipyrone) is a pyrazolone derivative that belongs to the group of nonacid nonopioids. It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability. Metamizole was formerly marketed in the US as Dimethone tablets and injection, Protemp oral liquid, and other drug products, and was withdrawn due to...
Approved
Investigational
Withdrawn
Matched Description: … Metamizole (dipyrone) is a pyrazolone derivative that belongs to the group of nonacid nonopioids. ... It is considered a potent analgesic and antipyretic with favourable gastrointestinal tolerability. …
Matched Mixtures name: … BIPASMIN COMPUESTO N ... DIPIRONA N- BULTILBROMURO DE HIOSCINA ... HIOSCINA N BUTIL BROMURO + DIPIRONA SODICA AMPOLLAS …
Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
Approved
Investigational
Matched Description: … Nitrendipine is a calcium channel blocker with marked vasodilator action. …
An ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (serotonin agonists).
Approved
Investigational
Matched Synonyms: … N'-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylurea …
Trolamine, which is also referred to as triethanolamine (TEA), is a tertiary amine and a triol. It is a bifunctional compound that exhibits both properties of alcohols and amines. Trolamine contains small amounts of diethanolamine and ethanolamine and may also act as an antioxidant against the auto-oxidation of animal and...
Approved
Matched Description: … Trolamine, which is also referred to as triethanolamine (TEA), is a tertiary amine and a triol. ... It is a bifunctional compound that exhibits both properties of alcohols and amines. ... It is commonly used as a pH adjuster and surfactant in industrial and cosmetic products such as skin …
Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched Description: … Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the ... selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a
Matched Mixtures name: … OLMEDOXTAN A® ... CARDIK® A 80/5 ... CARDIK® A 80/5 …
Matched Products: … A-B VASK 5 ... A-B VASK 10 ... AMLODIPIN RATIO 5MG N
Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. It functions as a contrast agent by opacifying blood vessels in the flow path of the contrast agent, permitting radiographic visualization of the internal structures until significant hemodilution occurs. Although iopromide can cause several serious adverse effects, including...
Approved
Matched Synonyms: … N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methylisophthalamide …
Matched Description: … Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. ... It functions as a contrast agent by opacifying blood vessels in the flow path of the contrast agent, ... favorable safety profile, with only 0.7% of patients in a 2 years study experiencing adverse events. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Norgestrel is synthetic steroidal progestin that is used in combination with ethinyl estradiol for oral contraception. Norgestrel is composed of a racemic mixture of two stereoisomers, dextronorgestrel and levonorgestrel. However, only the levorotary enantiomer (levonorgestrel) is biologically active.
Approved
Matched Description: … Norgestrel is composed of a racemic mixture of two stereoisomers, dextronorgestrel and levonorgestrel …
Pistachio allergenic extract is used in allergenic testing.
Approved
Lacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. Lacosamide exhibits a stereoselective mode of interaction with sodium channels. Lacosamide was first approved by the European Commission in August 2008 and was later...
Approved
Matched Synonyms: … (R)-2-acetamido-N-benzyl-3- methoxypropionamide ... (+)-(2R)-2-(ACETYLAMINO)-N-BENZYL-3-METHOXYPROPANAMIDE ... (2R)-2-(Acetylamino)-3-methoxy-N-(phenylmethyl)propanamide …
Matched Iupac: … (2R)-N-benzyl-2-acetamido-3-methoxypropanamide …
Matched Description: … Lacosamide exhibits a stereoselective mode of interaction with sodium channels. ... As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated …
Diphenylguanidine is a complexing agent used in the detection of metals and organic bases and used as an accelerator in the vulcanization of rubber. It is found in some rubber products. It is also a dermatological sensitizer and allergen. Sensitivity to diphenylguanidine may be identified with a clinical patch test.
Approved
Experimental
Matched Synonyms: … N,N'-diphenylguanidine …
Matched Iupac: … N,N'-diphenylguanidine …
Matched Description: … It is also a dermatological sensitizer and allergen. ... Sensitivity to diphenylguanidine may be identified with a clinical patch test. ... Diphenylguanidine is a complexing agent used in the detection of metals and organic bases and used as …
Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Synonyms: … N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol ... N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxel …
Matched Description: … Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel]. ... Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment ... [A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …
Matched Products: … DOCETAXEL DONG-A
Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. It targets cell surface tyrosine kinase receptors and downstream intracellular kinases that are implicated in tumour cell proliferation and tumour angiogenesis. First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also...
Approved
Investigational
Matched Synonyms: … N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea ... 4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide …
Matched Iupac: … 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide …
Matched Description: … Sorafenib is a bi-aryl urea and an oral multikinase inhibitor. …
Matched Categories: … UGT1A9 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
A guanido-neuraminic acid that is used to inhibit neuraminidase.
Approved
Investigational
Matched Synonyms: … 4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid …
Matched Description: … A guanido-neuraminic acid that is used to inhibit neuraminidase. …
Clomipramine, the 3-chloro analog of imipramine, is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, clomipramine does not affect mood or arousal, but may cause sedation. In depressed individuals,...
Approved
Investigational
Vet approved
Matched Synonyms: … 3-(3-chloro-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine ... 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine …
Matched Description: … See toxicity section below for a complete listing of side effects. ... In depressed individuals, clomipramine exerts a positive effect on mood. ... They contain a tricyclic ring system with an alkyl amine substituent on the central ring. …
Matched Categories: … Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Phenylbutyric acid is a fatty acid and a derivative of butyric acid naturally produced by colonic bacteria fermentation. It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting as a chemical chaperone. It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders.[L386,L42105]
Approved
Investigational
Matched Synonyms: … 4-Phenyl-n-butyric acid ... γ-Phenyl-n-butyric acid …
Matched Description: … as a chemical chaperone. ... Phenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria ... It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting …
North American Coral Snake Antivenin (Equine) is a horse-derived antivenin indicated for the treatment of envenomation caused by North American coral snake bites. It is intravenously administered so that the antivenin binds to and neutralizes coral snake venom. The antivenin is a refined, concentrated, and lyophilized preparation of serum globulins...
Approved
Experimental
Matched Description: … North American Coral Snake Antivenin (Equine) is a horse-derived antivenin indicated for the treatment ... The antivenin is a refined, concentrated, and lyophilized preparation of serum globulins obtained by …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Singapore/INFIMH-16-0019/2016 NIB-104 (H3N2) antigen (formaldehyde inactivated) …
Matched Description: … A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Nebraska/14/2019 (H1N1) antigen (MDCK cell derived, propiolactone inactivated) …
Matched Description: … A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed …
Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergic medications.[A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the...
Approved
Investigational
Vet approved
Matched Description: … [L33105] Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications ... and is considered to have a wider therapeutic window than [tiotropium]. ... Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. …
Meningococcal group A polysaccharide is group-specific polysaccharide antigens extracted and purified from Neisseria meningitidis serogroup A. N. meningitidis is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia. It is subcutaneously administered as an active immunization against the invasive meningococcal disease caused by the serogroup A.
Approved
Experimental
Investigational
Matched Synonyms: … Neisseria meningitidis group A polysaccharide antigen, A ... Meningococcal group A polysaccharide ... Meningococcal polysaccharide antigen group A
Matched Name: … Meningococcal polysaccharide vaccine group A
Matched Description: … *N. meningitidis* is a bacteria that causes endemic and epidemic diseases including meningitis and meningococcemia ... from *Neisseria meningitidis* serogroup A. ... Meningococcal group A polysaccharide is group-specific polysaccharide antigens extracted and purified …
Matched Mixtures name: … Menomune-A/c/y/w-135 ... Menomune-A/c/y/w-135 ... Menomune-A/c/y/w-135 …
Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin...
Approved
Matched Iupac: … 1-carbamimidamido-N,N-dimethylmethanimidamide …
Matched Description: … a clinically significant reduction of plasma fasting insulin levels. ... Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management ... It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and …
Matched Products: … METFORMIN ARISTO N 500MG ... METFORMIN ARISTO N 850MG ... METFORMIN ARISTO N 1000MG …
Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Synonyms: … 2-(N-cyclopropylmethyl-4,5α-epoxy-3-hydroxy-6-methoxy-6,14-endo-ethanomorphinan-6α-yl)-3,3-dimethyl-2 …
Matched Description: … Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist ... Buprenorphine has a number of unique pharmacokinetic and pharmacodynamic properties that make it a preferred ... Clinically, this results in a slow onset of action and a clinical phenomenon known as the "ceiling effect …
Displaying drugs 51 - 75 of 8741 in total