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Displaying drugs 76 - 100 of 11837 in total
Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Approved
Investigational
Matched Synonyms: … 2-Hydroxy-4-methoxybenzophenone ... 4-Methoxy-2-hydroxybenzophenone ... Benzophenone-3
Matched Iupac: … 2-benzoyl-5-methoxyphenol …
Matched Mixtures name: … Esika 3-IN-1 Pro Make Up Foundation SPF 20 Base De Maquillaje Para Rostro 3-EN-1 Pro Fps 20 (rose 4) ... Esika 3-IN-1 Pro Make Up Foundation SPF 20 Base De Maquillaje Para Rostro 3-EN-1 Pro Fps 20 (beige 4) ... Esika 3-IN-1 Pro Make Up Foundation SPF 20 Base De Maquillaje Para Rostro 3-EN-1 Pro Fps 20 (rose 2) …
Malaria is a protozoan disease that places an enormous burden on human health in endemic areas around the world. The 2020 World Health Organization malaria report indicates a 60% decrease in the global malaria fatality rate between 2000 to 2019. Despite this, malaria remains a significant cause of morbidity and...
Approved
Investigational
Matched Synonyms: … alpha-2-Piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol ... [(R*,S*)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol …
Matched Iupac: … [2,8-bis(trifluoromethyl)quinolin-4-yl](piperidin-2-yl)methanol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Rosoxacin is a quinolone derivative antibiotic for the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients. Rosoxacin is known to be effective against penicillin resistant strains and is a single dose orally administered drug, which avoids all complications of parenteral administration seen with...
Approved
Investigational
Matched Synonyms: … 1-ethyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinolinecarboxylic acid …
Matched Iupac: … 1-ethyl-4-oxo-7-(pyridin-4-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Synonyms: … 1-Cyclopropyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ... 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid ... 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid …
Matched Iupac: … 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Mixtures name: … InfectoCiproCort 3 mg/ml + 0,25 mg/ml Ohrentropfen, Lösung …
Matched Categories: … MATE 1 Inhibitors ... MATE 1 Substrates ... MATE 2 Inhibitors ... Heterocyclic Compounds, 2-Ring …
Matched Products: … NOVAFLOX EYE DROPS 3 mg/ml ... CILOXAN STERILE OPHTHALMIC OINTMENT 3 mg/g ... CIROK INJECTION 2 mg/ml …
Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic chemical UV-B filter. It is used in cosmetic products such as sunscreen to provide skin protection against UV rays. While its effects on the human reproductive system as an endocrine disruptor are being investigated, its use in...
Approved
Matched Synonyms: … 3-(4-methylbenzylidene)camphor ... 4-MBC ... 4-methylbenzylidene camphor …
Matched Iupac: … (3E)-1,7,7-trimethyl-3-[(4-methylphenyl)methylidene]bicyclo[2.2.1]heptan-2-one …
Matched Description: … Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic …
Matched Mixtures name: … Outback 2-in-1 Insect Repellent and Protective Sunscreen ... Secret Key Natural Cc Cushion Spf50 Plus / 01 Light Cc …
Ceritinib is used for the treatment of adults with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) following failure (secondary to resistance or intolerance) of prior crizotinib therapy. About 4% of patients with NSCLC have a chromosomal rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like...
Approved
Matched Synonyms: … N-{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl} ... propane-2-sulfonamide …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … About 4% of patients with NSCLC have a chromosomal rearrangement that generates a fusion gene between ... EML4 (echinoderm microtubule-associated protein-like 4) and ALK (anaplastic lymphoma kinase), which …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug developed specifically targeting FLT3, as other agents with FLT3 inhibition activities were investigated with other targets in mind. Additionally, quizartinib also demonstrates inhibitory activity toward FLT3 with internal tandem duplication (ITD), although...
Approved
Investigational
Matched Synonyms: … N-(5-(1,1-Dimethylethyl)isoxazol-3-yl)-N'-(4-(7-(2-(morpholin-4-yl)ethoxy)imidazo(2,1-b)benzothiazol- ... 2-yl)phenyl)urea …
Matched Iupac: … 3-(5-tert-butyl-1,2-oxazol-3-yl)-1-(4-{10-[2-(morpholin-4-yl)ethoxy]-7-thia-2,5-diazatricyclo[6.4.0.0²,⁶ ... ]dodeca-1(8),3,5,9,11-pentaen-4-yl}phenyl)urea …
Matched Description: … Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug …
Matched Salts cas: … 1132827-21-4
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Approved
Matched Synonyms: … 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsäure ... 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … นอร์สเป็ค 4
Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Synonyms: … -(1-4))-2-deoxy-D-streptamine ... O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl ... 3'-Deoxykanamycin B …
Matched Iupac: … (2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5 ... -hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-6-(hydroxymethyl)oxane-3,5-diol …
Matched Salts cas: … 49842-07-1
Matched Mixtures name: … TOBRALOT 5 MG+3 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET ... DEXAVITAL TOBRAMICIDADEXAMETASONA(3 MG+1MG)/ML ... TOBRAZON %0.3 + %0.1 GÖZ DAMLASI, SÜSPANSİYON, 1 ADET …
Matched Products: … TOBEL 20 MG/2 ML AMPUL, 3 ADET ... TOBEL 80 MG/2 ML AMPUL, 3 ADET ... TOBEL 20 MG/2 ML AMPUL, 1 ADET …
Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before...
Approved
Matched Synonyms: … (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine …
Matched Iupac: … (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine …
An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Approved
Matched Synonyms: … (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydronaphthacen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside ... 4-Demethoxydaunomycin ... 4-Demethoxydaunorubicin …
Matched Iupac: … (7S,9S)-9-acetyl-7-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,9,11-trihydroxy-5,7,8,9,10,12 …
Matched Products: … ZAVEDOS 5 MG FLAKON, 1 ADET ... ZAVEDOS 10 MG FLAKON, 1 ADET ... ZAVEDOS® SOLUCIÓN INYECTABLE 1 MG/ML …
Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. It is selective for the H1 receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier - this is in contrast to previous first-generation antihistamines, such as diphenhydramine, which readily bind to off-targets...
Approved
Investigational
Matched Synonyms: … 4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acid …
Matched Iupac: … 2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid …
Matched Description: … [L4269] It is selective for the H1 receptor, carries little-to-no activity at off-targets, …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label] . Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate .
Approved
Matched Synonyms: … 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine …
Matched Iupac: … 6,7-dimethoxy-2-[4-(oxolane-2-carbonyl)piperazin-1-yl]quinazolin-4-amine …
Matched Description: … Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign ... Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Terazosin-1 ... HYTRIN TABLET 1 mg ... Uroflo 1 mg - Tabletten …
Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids,...
Approved
Investigational
Matched Synonyms: … 4-Hydroxyphenol …
Matched Mixtures name: … Throwers Pbc No. 1 ... Hyaluronic Acid Sodium Salt 1% / Hydroquinone 6% ... Hydrocortisone 1% / Hydroquinone 8% / Tretinoin 0.05% …
Matched Products: … Melquin 3 ... HIDROQUINONA 3 % LOCION ... DIVAMERICA® 3% SOLUCIÓN TOPICA …
Approved
Investigational
Matched Synonyms: … 5,7-dichloro-2-((ethylamino)methyl)-8-hydroxy-3-methylquinazolin-4(3h)-one …
Matched Iupac: … 5,7-dichloro-2-[(ethylamino)methyl]-8-hydroxy-3-methyl-3,4-dihydroquinazolin-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Approved
Withdrawn
Matched Synonyms: … 2-(4-(2-Thenoyl)phenyl)propionsäure ... 4-(2-Thenoyl)hydratropsäure ... 2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid …
Matched Iupac: … 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid …
Matched Categories: … Non COX-2 selective NSAIDS …
Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine.[A462, L12978] Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, and zolmitriptan. Triptans...
Approved
Investigational
Matched Synonyms: … 4-[[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one ... (S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one …
Matched Iupac: … (4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Products: … MIGTERA 5 MG FİLM TABLET, 2 ADET ... MIGTERA 2.5 MG FİLM TABLET, 2 ADET ... MIGTERA 5 MG FİLM TABLET, 3 ADET …
Phenylbutyric acid is a fatty acid and a derivative of butyric acid naturally produced by colonic bacteria fermentation. It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting as a chemical chaperone. It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders.[L386,L42105]
Approved
Investigational
Matched Synonyms: … 4-phenylbutyrate ... 4-phenylbutyric acid ... 4-Phenyl-n-butyric acid …
Matched Iupac: … 4-phenylbutanoic acid …
Dexlansoprazole is a new-generation proton pump inhibitor (PPI) used for the management of symptoms associated with gastroesophageal reflux disease (GERD) and erosive esophagitis. Dexlansoprazole is the R-enantiomer of DB00448, which is composed of a racemic mixture of the R- and S-enantiomers. Compared to the older generation of PPIs (which includes...
Approved
Investigational
Matched Synonyms: … (+)-2-((R)-((3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)PYRIDIN-2-YL)METHYL)SULFINYL)-1H-BENZIMIDAZOLE ... 1H-BENZIMIDAZOLE, 2-((R)-((3-METHYL-4-(2,2,2-TRIFLUOROETHOXY)-2-PYRIDINYL)METHYL)SULFINYL)- ... 2-((R)-((3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole …
Matched Iupac: … 2-[(R)-[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methanesulfinyl]-1H-1,3-benzodiazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... 2-Pyridinylmethylsulfinylbenzimidazoles ... Heterocyclic Compounds, 2-Ring …
Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.
Approved
Investigational
Matched Synonyms: … N-methyl-2-(3-(1-methylpiperiden-4-yl)indole-5-yl)ethanesulfonamide ... N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamide …
Matched Iupac: … N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethane-1-sulfonamide …
Matched Salts cas: … 143388-64-1
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Products: … NARAMIG 2.5 MG FILM TABLET, 2 ADET …
A non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-(p-chlorphenyl)-3-methyl-1,3-perhydrothiazin-4-on-1,1-dioxide ... 2-(p-chlorophenyl)tetrahydro-3-methyl-4H-1,3-thiazin-4-one 1,1-dioxide …
Matched Iupac: … 2-(4-chlorophenyl)-3-methyl-1lambda6,3-thiazinane-1,1,4-trione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … 4-Amino-3-(4-chlorophenyl)butyric acid ... DL-4-Amino-3-p-chlorophenylbutanoic acid ... beta-(4-Chlorophenyl)gaba …
Matched Iupac: … 4-amino-3-(4-chlorophenyl)butanoic acid …
Matched Salts cas: … 28311-31-1
Matched Products: … Baclofen Sintetica 2 mg/ml Intrathekal Infusionslösung ... BACLOFEN ® 0.05 MG/ 1 ML ... Lioresal intrathekal 0,05 mg/1 ml - Ampullen …
Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase. It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 (echinoderm microtubule-associated protein-like 4) fusion protein that causes proliferation of NSCLC cells. Inhibition of ALK...
Approved
Investigational
Matched Synonyms: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3- …
Matched Iupac: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-5H,6H,11H-benzo[b]carbazole-3-carbonitrile …
Matched Description: … non-small cell lung cancer (NSCLC) expressing the ALK-EML4 (echinoderm microtubule-associated protein-like 4) …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …
Diethylamino hydroxybenzoyl hexyl benzoate is a UV filter with high absorption in the UV-A range. Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic photodamage, diethylamino hydroxybenzoyl hexyl benzoate is an oil-soluble UV filter that may be incorporated in the oil phase of...
Approved
Matched Synonyms: … Hexyl 2-(4-(diethylamino)-2-hydroxybenzoyl)benzoate …
Matched Iupac: … hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate …
An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of...
Approved
Matched Synonyms: … 6-Methoxy-8-(4-amino-1-methylbutylamino)quinoline ... 8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline ... 8-((4-Amino-1-methylbutyl)amino)-6-methoxyquinoline …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 76 - 100 of 11837 in total