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AstraZeneca COVID-19 Vaccine

The AstraZeneca COVID-19 Vaccine (previously known as ChAdOx1 nCoV-19 or AZD1222) is one of several vaccines developed in 2020 for the prevention of COVID-19 caused by SARS-CoV-2.[L12669,L32649] The ChAdOx1 viral vector was developed at the University of Oxford and has been investigated as a potential vector for vaccines against another...
Approved
Investigational
Matched Synonyms: … Coronavirus Disease (COVID-19) vaccine ChAdOx1 nCoV-19 ... ChAdOx1 nCoV-19 …
Matched Name: … AstraZeneca COVID-19 Vaccine …
Matched Description: … The AstraZeneca COVID-19 Vaccine (previously known as ChAdOx1 nCoV-19 or AZD1222) is one of several vaccines ... developed in 2020 for the prevention of COVID-19 caused by SARS-CoV-2. ... [A192822,L12672] The ChAdOx1 nCoV-19 vaccine, produced in a partnership between The University of Oxford's …
Matched Categories: … COVID-19 Vaccines ... Experimental Unapproved Treatments for COVID-19 …
Matched Products: … Astrazeneca Covid-19 Vaccine ... Covid-19 Vaccine Astrazeneca …

Moderna COVID-19 Vaccine

The Moderna COVID-19 Vaccine (mRNA-1273) is a novel mRNA-based vaccine encapsulated in a lipid nanoparticle that encodes for a full-length pre-fusion stabilized spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coronavirus disease 2019 (COVID-19) is a highly contagious infectious disease caused by the novel coronavirus, SARS-CoV-2, leading...
Approved
Investigational
Matched Name: … Moderna COVID-19 Vaccine …
Matched Description: … NCT04283461) was initiated in March 2020 in which 45 subjects received two intramuscular doses (on days 1 ... The Moderna COVID-19 Vaccine (mRNA-1273) is a novel mRNA-based vaccine encapsulated in a lipid nanoparticle ... COVID-19 has high interpatient variability in symptoms, ranging from mild symptoms to severe illness. …
Matched Mixtures name: … Moderna COVID-19 Vaccine, Bivalent ... Moderna COVID-19 Vaccine, Bivalent …
Matched Categories: … COVID-19 Vaccines ... Experimental Unapproved Treatments for COVID-19 …
Matched Products: … Moderna COVID-19 Vaccine ... Covid-19 Vaccine Moderna …

Alpha-1-proteinase inhibitor

Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Approved
Matched Synonyms: … .-1 protease inhibitor ... Alfa-1-antitripsina ... Alpha 1-antitrypsin …
Matched Name: … Alpha-1-proteinase inhibitor …
Matched Description: … Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol …
Matched Categories: … Human alpha-1 Proteinase Inhibitor …
Matched Products: … PROLASTIN C 1000 MG IV İNFÜZYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET …

Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine

The Covifenz COVID-19 vaccine (plant-based virus-like particles (VLP), recombinant, adjuvanted) is a plant-based vaccine developed in partnership by Medicago and GlaxoSmithKline which is approved in Canada for the prevention of COVID-19. It is composed of VLPs expressing SARS-CoV-2 spike protein trimers (stabilized in a pre-fusion conformation) and is mixed with...
Approved
Matched Name: … Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine …
Matched Description: … COVID-19 vaccine]) and nucleic acid vaccines (e.g. the [Moderna COVID-19 vaccine]). ... The Covifenz COVID-19 vaccine (plant-based virus-like particles (VLP), recombinant, adjuvanted) is a ... partnership by Medicago and GlaxoSmithKline which is approved in Canada for the prevention of COVID-19 …
Matched Categories: … COVID-19 Vaccines …

1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol))

Palmitoyloleoyl-phosphatidylglycerol was a component of Surfaxin, discontinued in 2017, which acted as a surfactant [FDA Label]. The product was meant to compensate for alveolar surfactant deficiency and reduce to likelihood of alveolar collapse leading to acute respiratory collapse.
Approved
Experimental
Matched Synonyms: … 1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)) ... PG(16:0/18:1) ... PG(16:0/18:1(9Z)) …
Matched Name: … 1-Palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)) …
Matched Salts name: … 1-palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)), sodium salt …

Influenza A virus A/Washington/19/2020 (H1N1) antigen (MDCK cell derived, propiolactone inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Washington/19/2020 (H1N1) antigen (MDCK cell derived, propiolactone inactivated) …

Influenza B virus B/Wisconsin/1/2010 live (attenuated) antigen

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Synonyms: … Influenza B Virus B/wisconsin/1/2010 Live(attenuated) Antigen …
Matched Name: … Influenza B virus B/Wisconsin/1/2010 live (attenuated) antigen …

VidPrevtyn Beta

VidPrevtyn Beta is an adjuvanted, recombinant COVID-19 vaccine developed collaboratively by GlaxoSmithKline (GSK) and Sanofi Pasteur. It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant DNA technology using a baculovirus expression system in an insect cell line that is derived from Sf9 cells of the fall...
Approved
Investigational
Matched Synonyms: … COVID-19 Vaccine (recombinant, adjuvanted) …
Matched Description: … VidPrevtyn Beta is an adjuvanted, recombinant COVID-19 vaccine developed collaboratively by GlaxoSmithKline ... approved in the European Union for use as a booster dose in patients who have previously received a COVID-19 …
Matched Categories: … COVID-19 Vaccines …

Dienogest

Dienogest is an orally-active semisynthetic progestogen which also possesses the properties of 17α-hydroxyprogesterone. It is a derivative of 19-nortestosterone and has antiandrogenic properties. It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not...
Approved
Matched Synonyms: … 17alpha-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile …
Matched Description: … It is a derivative of 19-nortestosterone and has antiandrogenic properties. …
Matched Mixtures name: … Velbienne 1 mg/2 mg Filmtabletten ... VELBİENNE 2 MG/1 MG FİLM KAPLI TABLET, 28 ADET …

Linaclotide

Linaclotide is a synthetic 14-amino acid cyclic peptide and first-in-class guanylate cyclase-C (G-CC) agonist.[A260271, L47211] Linaclotide is structurally related to human guanylin and uroguanylin, paracrine peptide hormones that are endogenous activators of GC-C. It is also a homolog of a heat-stable enterotoxin derived from Escherichia coli, the first natural ligand...
Approved
Matched Synonyms: … (9-L-TYROSINE)HEAT-STABLE ENTEROTOXIN (ESCHERICHIA COLI)-(6-19)-PEPTIDE ... GLUTAMYL-L-TYROSYL-L-CYSTEINYL-L-CYSTEINYL-L-ASPARAGINYL-L-PROLYL-L-ALANYL-L-CYSTEINYL-L-THREONYLGLYCYL-L-CYSTEINYL-, CYCLIC (1- …
Matched Iupac: … ,7S,13S,16R,21R,24R,27S,30S,33R,38R,44S)-21-amino-13-(carbamoylmethyl)-27-(2-carboxyethyl)-44-[(1R)-1- …

Zileuton

Leukotrienes are substances that induce numerous biological effects including augmentation of neutrophil and eosinophil migration, neutrophil and monocyte aggregation, leukocyte adhesion, increased capillary permeability, and smooth muscle contraction. These effects contribute to inflammation, edema, mucus secretion, and bronchoconstriction in the airways of asthmatic patients. Zileuton relieves such symptoms through its...
Approved
Investigational
Withdrawn
Matched Synonyms: … (±)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea ... N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea ... N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea …
Matched Iupac: … 1-[1-(1-benzothiophen-2-yl)ethyl]-1-hydroxyurea …

Propranolol

Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.
Approved
Investigational
Matched Synonyms: … 1-((1-Methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanol ... 1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol …
Matched Iupac: … 1-(naphthalen-1-yloxy)-3-[(propan-2-yl)amino]propan-2-ol …
Matched Products: … HEMANGİOL 3,75 MG/ML ORAL ÇÖZELTİ, 1 ADET …

Calcium carbonate

Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. Calcium carbonate may also...
Approved
Investigational
Matched Synonyms: … Calcium carbonate (1:1) ... Carbonic acid calcium salt (1:1) …
Matched Mixtures name: … PNV Tabs 29-1 ... Trinatal Rx 1 ... PNV Tabs 29-1 …

Amantadine

An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and...
Approved
Matched Synonyms: … 1-adamantanamine ... 1-adamantylamine ... 1-aminoadamantane …
Matched Iupac: … adamantan-1-amine …

Ciprofloxacin

Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Synonyms: … 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid ... 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Iupac: … 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Categories: … MATE 1 Inhibitors ... MATE 1 Substrates …
Matched Products: … CIPROFLAXACINA 1 % ... CIFLOXIN 1% SOLUCION OTICA ... INFÜZYONLUK ÇÖZELTİ, 1 ADET …

Mepivacaine

A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia. Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168)
Approved
Vet approved
Matched Synonyms: … 1-methyl-2',6'-pipecoloxylidide ... (+-)-1-Methyl-2',6'-pipecoloxylidide ... N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide …
Matched Iupac: … N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide …
Matched Mixtures name: … 2% Polocaine Dental With Levonordefrin 1:20,000 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Carbocaine 1% ... Carbocaine Liq 1% ... ANESTOCAINA SIMPLE 1% …

Astemizole

Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice.
Approved
Withdrawn
Matched Synonyms: … 1-(p-Fluorobenzyl)-2-((1-(2-(p-methoxyphenyl)ethyl)piperid-4-yl)amino)benzimidazole ... 1-(p-Fluorobenzyl)-2-((1-(p-methoxyphenethyl)-4-piperidyl)amino)benzimidazole …
Matched Iupac: … 1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-1,3-benzodiazol-2-amine …
Matched Products: … AZTEMIZOL SUSPENSION 1 MG/ML ... ASTEMIZOL 1 MG/ML SUSPENSION ... ASTEMIZOL SUSPENSION 1 MG./ML. …

Ferrous cysteine glycinate

Approved
Matched Synonyms: … Ferrous cysteine glycinate chelate (1:2:1) …

Teriparatide

Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Synonyms: … PTH 1-34 ... PTH (1-34) …
Matched Products: … Teriparatide Acetate (hPTH (1-34)) …

Guanethidine

An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues. [PubChem]
Approved
Matched Synonyms: … 2-(1'-Azacyclooctyl)ethylguanidine ... (2-(Octahydro-1-azocinyl)ethyl)guanidine ... (2-(hexahydro-1(2h)-azocinyl)ethyl)guanidine …
Matched Iupac: … N''-[2-(azocan-1-yl)ethyl]guanidine …

Zavegepant

Zavegepant (BHV-3500) is a calcitonin gene-related peptide (CGRP) receptor antagonist. CGRP is released from sensory nerves and acts as a strong vasodilator, and thanks to these properties, it is involved in pain pathways. CGRP receptors are expressed in the central and peripheral nervous system; however, CGRP does not cross the...
Approved
Investigational
Matched Synonyms: … )-2-(4-(1-methyl-4-piperidinyl)-1-piperazinyl)-2-oxoethyl)- ... 1-piperidinecarboxamide, 4-(1,2-dihydro-2-oxo-3-quinolinyl)-n-((1r)-1-((7-methyl-1h-indazol-5-yl)methyl …
Matched Iupac: … N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4 ... -(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide …
Matched Categories: … Experimental Unapproved Treatments for COVID-19 ... MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …

Glatiramer

Glatiramer acetate is a mix of synthetic polypeptides that includes L-glutamic acid, L-alanine, L-tyrosine, and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. Since glatiramer acetate is a heterogeneous drug, there is limited information about its physicochemical properties. Originally, glatiramer acetate was designed as a...
Approved
Investigational
Matched Synonyms: … COP 1 ... COP-1 ... Copolymer-1 …

Netilmicin

Netilmicin is a semisynthetic 1-N-ethyl derivative of sisomycin, an aminoglycoside antibiotic with action similar to gentamicin, but less ear and kidney toxicity. Netilmicin inhibits protein synthesis in susceptible organisms by binding to the bacterial 30S ribosomal subunit and interfering with mRNA binding and the acceptor tRNA site. The bactericidal effect...
Approved
Investigational
Matched Synonyms: … 1-N-Ethylsisomicin …
Matched Description: … Netilmicin is a semisynthetic 1-N-ethyl derivative of sisomycin, an aminoglycoside antibiotic with action …
Matched Mixtures name: … NETİZON 5 MG+15 MG/5 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET ... DEXANETİL % 0,1 + % 0,3 GÖZ DAMLASI, ÇÖZELTİ, 1 ADET ... GLYDEXİL PLUS % 0.3 + % 0.1 GÖZ DAMLASI, ÇÖZELTİ, 1 ADET …
Matched Products: … GLYNETİL % 0.3 GÖZ DAMLASI, ÇÖZELTİ, 1 ADET ... NETİLCİN %0.3 GÖZ DAMLASI, ÇÖZELTİ, 1 ADET …

Nickel sulfate

Nickel sulfate is used in allergenic testing.
Approved
Experimental
Matched Synonyms: … Nickel sulfate(1:1) …

Cetylpyridinium

Cetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. In these products, it generally mediates an antiseptic activity and protective action against dental plaque and reducing gingivitis.
Approved
Matched Synonyms: … 1-hexadecylpyridinium …
Matched Iupac: … 1-hexadecylpyridin-1-ium …
Matched Mixtures name: … MEBUCAIN 2 MG/1 MG NANELI PASTIL (20 ADET) …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 1 - 25 of 10589 in total