Sympathomimetics

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
DrugDrug NameDrug Description
DB00397PhenylpropanolamineA sympathomimetic that was previously used in nasal decongestants and weight loss products, but has been withdrawn by the FDA due to safety risks and lack of efficacy.
DB00182AmphetamineA CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).
DB00191PhentermineA sympathomimetic anorectic agent used as a short-term adjunct therapy that is included in a regimen of weight reduction in cases of exogenous obesity.
DB00211MidodrineAn alpha-adrenergic antagonist used to treat orthostatic hypotension.
DB00368NorepinephrineA sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest.
DB00388PhenylephrineAn alpha-1 adrenergic antagonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics.
DB00598LabetalolAn alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome.
DB00610MetaraminolFor the treatment and prevention of hypotension due to hemorrhage, spinal anesthesia, and shock associated with brain damage
DB00668EpinephrineA hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
DB00723MethoxamineAn alpha adrenergic agonist used to treat hypotension.
DB00816OrciprenalineA beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD.
DB00830PhenmetrazineUsed as an anorectic in the treatment of obesity.
DB00841DobutamineA beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery.
DB00865BenzphetamineA sympathomimetic used to manage exogenous obesity short term.
DB00867RitodrineAn adrenergic beta agonist used to treat premature labor.
DB00871TerbutalineA beta-2 adrenergic agonist used as a bronchodilator and to prevent premature labor.
DB00935OxymetazolineAn alpha-1A adrenoceptor agonist used to treat nasal congestion, allergic reactions of the eye, and facial erythema associated with rosacea.
DB00988DopamineA catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension.
DB01064IsoprenalineA non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block; it is structurally related to epinephrine.
DB01193AcebutololA selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults.
DB01288FenoterolA beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma.
DB01364EphedrineAn alpha and beta-adrenergic agonist used for the management of respiratory conditions related to bronchial asthma, such as wheezing, shortness of breath, and tightness of chest.
DB01365MephentermineA sympathomimetic agent used in the treatment of hypotension.
DB01366ProcaterolA beta-2 adrenergic receptor agonist and bronchodilator used for the treatment of asthma and chronic obstructive pulmonary disease (COPD).
DB01407ClenbuterolUsed as a bronchodilator in the treatment of asthma patients.
DB01556ChlorphentermineUsed as an appetite suppressant.
DB01577MetamfetamineA sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and exogenous obesity.
DB04846CeliprololCeliprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris.
DB06152NylidrinA vasodilator used to treat patients with peripheral vascular disorders, and elderly patients with symptoms associated with organic mental disorders.
DB06764TetryzolineAn alpha-adrenergic agonist used in the temporary symptomatic relief of discomfort and redness of the eyes due to minor irritations.
DB08841TyramineTyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine compound and trace amine derived from the amino acid tyrosine. Tyramine acts by inducing the release of catecholamine. An...
DB08941IsoxsuprineA beta-adrenergic agonist used in the symptomatic treatment of cerebrovascular insufficiency, peripheral vascular disease of arteriosclerosis obliterans, thromboangiitis obliterans (Buerger's disease) and Raynaud's disease.
DB08985EtilefrineEtilefrine is an adrenergic agonist that appears to interact with beta-2 and some alpha adrenergic receptors. It has been used as a vasoconstrictor agent.
DB09203SynephrineSynephrine, also referred to as, p-synephrine, is naturally occurring alkaloid. It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer...
DB09352HydroxyamphetamineAn indirectly acting sympathomimetic agent producing mydriasis for diagnostic purposes.
DB11124RacepinephrineA bronchodilator used to treat intermittent asthma.
DB12752BucindololBucindolol has been investigated in Heart Failure.
DB13064TramazolineTramazoline is under investigation in clinical trial NCT01601509 (Nasal Tramazoline and Dexamethazone in Obstructive Sleep Apnea (OSA) Patients Tramazoline and).
DB13341FenozoloneNot Annotated
DB13692TretoquinolNot Annotated
DB13757EpanololEpanolol is an beta blocker.
DB13777PrenalterolNot Annotated
DB13852MefenorexNot Annotated
DB00852PseudoephedrineAn alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis.
DB00937DiethylpropionAn appetite suppressant used for the short term treatment of exogenous obesity in addition to calorie restriction.
DB01255LisdexamfetamineA central nervous system (CNS) stimulant used to treat attention deficit hyperactivity disorder (ADHD) and moderate to severe eating disorders.
DB01576DextroamphetamineA sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.
DB01442MMDAMMDA is a recreational drug. It has no current medical uses and is a Schedule I controlled substance in the USA at present.
DB01454MidomafetamineClinical trials are now testing the therapeutic potential of MDMA for post-traumatic stress disorder (PTSD) and anxiety associated with terminal cancer. MDMA is one of the four most widely used...
DB014672,5-Dimethoxy-4-ethylamphetamineNot Available
DB014844-Bromo-2,5-dimethoxyamphetamineNot Available
DB01509TenamfetamineAn amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons...
DB09480Iofetamine I-123Not Annotated
DB12080RitobegronRitobegron is under investigation in clinical trial NCT02256735 (Study to Investigate the Effect of KUC 7483 CL on the QT/QTc Interval of the ECG in Comparison to Placebo and Moxifloxacin...
DB13108MephedroneMephedrone has been investigated in Alcohol-Related Disorders and Amphetamine-Related Disorders.
DB13624MethoxyphenamineNot Annotated
DB13703GepefrineNot Annotated
DB139402,5-Dimethoxy-4-ethylthioamphetamine2,5-Dimethoxy-4-ethylthioamphetamine (ALEPH-2) is a phenylisopropylamine derivative with alleged anxiolytic and hallucinogenic properties.
DB01566MethylenedioxyethamphetamineNot Available
DrugDrug NameTargetType
DB00397PhenylpropanolamineAmine oxidase [flavin-containing] Aenzyme
DB00397PhenylpropanolamineDopamine D1 receptortarget
DB00397PhenylpropanolamineBeta-1 adrenergic receptortarget
DB00397PhenylpropanolamineBeta-2 adrenergic receptortarget
DB00397PhenylpropanolamineAlpha-2 adrenergic receptorstarget
DB00182AmphetamineSodium-dependent dopamine transportertarget
DB00182AmphetamineCocaine- and amphetamine-regulated transcript proteintarget
DB00182AmphetamineTrace amine-associated receptor 1target
DB00182AmphetamineCytochrome P450 2D6enzyme
DB00182AmphetamineSolute carrier family 22 member 3transporter
DB00182AmphetamineSolute carrier family 22 member 5transporter
DB00182AmphetamineSynaptic vesicular amine transportertarget
DB00182AmphetamineCytochrome P450 2A6enzyme
DB00182AmphetamineSodium-dependent noradrenaline transportertarget
DB00182AmphetamineAlpha adrenergic receptortarget
DB00182AmphetamineBeta adrenergic receptortarget
DB00182AmphetamineDopamine D2 receptortarget
DB00182AmphetamineAmine oxidase [flavin-containing] Btarget
DB00182AmphetamineSodium-dependent serotonin transportertarget
DB00182AmphetamineMonoamine oxidasetarget
DB00182Amphetaminevesicular monoamine transporter 2 (VMAT2)target
DB00191PhentermineSodium-dependent noradrenaline transportertarget
DB00191PhentermineSodium-dependent dopamine transportertarget
DB00191PhentermineAmine oxidase [flavin-containing] Atarget
DB00191PhentermineAmine oxidase [flavin-containing] Btarget
DB00191PhentermineSodium-dependent serotonin transportertarget
DB00191PhenterminePro-neuropeptide Ytarget
DB00191PhentermineCytochrome P450 3A4enzyme
DB00211MidodrineAlpha-1A adrenergic receptortarget
DB00211MidodrineAlpha-1B adrenergic receptortarget
DB00211MidodrineCytochrome P450 2D6enzyme
DB00211MidodrineSolute carrier family 15 member 1transporter
DB00211MidodrineAlpha-1D adrenergic receptortarget
DB00368NorepinephrinePhenylalanine-4-hydroxylasetarget
DB00368NorepinephrineAlpha-1A adrenergic receptortarget
DB00368NorepinephrineAlpha-1B adrenergic receptortarget
DB00368NorepinephrineAlpha-1D adrenergic receptortarget
DB00368NorepinephrineAlpha-2A adrenergic receptortarget
DB00368NorepinephrineAlpha-2B adrenergic receptortarget
DB00368NorepinephrineAlpha-2C adrenergic receptortarget
DB00368NorepinephrineBeta-1 adrenergic receptortarget
DB00368NorepinephrineBeta-2 adrenergic receptortarget
DB00368NorepinephrineBeta-3 adrenergic receptortarget
DB00368NorepinephrineSolute carrier family 22 member 2transporter
DB00368NorepinephrineSolute carrier family 22 member 3transporter
DB00368NorepinephrineSolute carrier family 22 member 5transporter
DB00368NorepinephrineSolute carrier family 22 member 1transporter
DB00368NorepinephrinePOU domain, class 5, transcription factor 1transporter
DB00368NorepinephrineSodium-dependent noradrenaline transportertransporter
DB00368NorepinephrineSynaptic vesicular amine transportertarget
DB00368NorepinephrineChromaffin granule amine transportertarget
DB00388PhenylephrineAlpha-1A adrenergic receptortarget
DB00388PhenylephrineAlpha-1B adrenergic receptortarget
DB00388PhenylephrineAmine oxidase [flavin-containing] Aenzyme
DB00388PhenylephrineAlpha-1D adrenergic receptortarget
DB00388PhenylephrineCytochrome P450 1A2enzyme
DB00388PhenylephrineSulfotransferase 1A3/1A4enzyme
DB00388PhenylephrineAmine oxidase [flavin-containing] Benzyme
DB00598LabetalolAlpha-1 adrenergic receptorstarget
DB00598LabetalolBeta-1 adrenergic receptortarget
DB00598LabetalolBeta-2 adrenergic receptortarget
DB00598LabetalolCytochrome P450 2D6enzyme
DB00598LabetalolCytochrome P450 2C19enzyme
DB00598LabetalolSerum albumincarrier
DB00598Labetalolalpha1-acid glycoproteincarrier
DB00598LabetalolATP-binding cassette sub-family B member 5transporter
DB00598LabetalolUDP-glucuronosyltransferase 1-1enzyme
DB00598LabetalolUDP-glucuronosyltransferase 2B7enzyme
DB00598LabetalolUDP-glucuronosyltransferase 1-9enzyme
DB00610MetaraminolAlpha-1A adrenergic receptortarget
DB00668EpinephrineAlpha-1A adrenergic receptortarget
DB00668EpinephrineBeta-1 adrenergic receptortarget
DB00668EpinephrineBeta-2 adrenergic receptortarget
DB00668EpinephrineSolute carrier family 22 member 2transporter
DB00668EpinephrineSolute carrier family 22 member 1transporter
DB00668EpinephrineCytochrome P450 2C9enzyme
DB00668EpinephrineCytochrome P450 3A4enzyme
DB00668EpinephrineAlpha-1B adrenergic receptortarget
DB00668EpinephrineAlpha-1D adrenergic receptortarget
DB00668EpinephrineAlpha-2A adrenergic receptortarget
DB00668EpinephrineAlpha-2B adrenergic receptortarget
DB00668EpinephrineTumor necrosis factortarget
DB00668EpinephrineCatechol O-methyltransferaseenzyme
DB00668EpinephrineMonoamine oxidaseenzyme
DB00723MethoxamineAlpha-1A adrenergic receptortarget
DB00723MethoxamineAlpha-1B adrenergic receptortarget
DB00723MethoxamineAlpha-1D adrenergic receptortarget
DB00816OrciprenalineBeta-2 adrenergic receptortarget
DB00830PhenmetrazineSodium-dependent noradrenaline transportertarget
DB00830PhenmetrazineSodium-dependent dopamine transportertarget
DB00841DobutamineBeta-1 adrenergic receptortarget
DB00841DobutamineCatechol O-methyltransferaseenzyme
DB00841DobutamineBeta-2 adrenergic receptortarget
DB00841DobutamineAlpha-1 adrenergic receptorstarget
DB00841DobutamineEstrogen receptor alphatarget
DB00865BenzphetamineAlpha-2A adrenergic receptortarget
DB00865BenzphetamineAlpha-1A adrenergic receptortarget
DB00865BenzphetamineCytochrome P450 3A4enzyme
DB00865BenzphetamineCytochrome P450 2B6enzyme
DB00865BenzphetamineNADPH--cytochrome P450 reductaseenzyme
DB00865BenzphetamineSynaptic vesicular amine transportertarget
DB00865BenzphetamineSodium-dependent dopamine transportertarget
DB00867RitodrineBeta-2 adrenergic receptortarget
DB00867Ritodrine6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00871TerbutalineBeta-2 adrenergic receptortarget
DB00871TerbutalineCholinesteraseenzyme
DB00871TerbutalineBeta-3 adrenergic receptortarget
DB00871TerbutalineBeta-1 adrenergic receptortarget
DB00935OxymetazolineAlpha-1A adrenergic receptortarget
DB00935OxymetazolineAlpha-2A adrenergic receptortarget
DB00935OxymetazolineAlpha-2C adrenergic receptortarget
DB00935OxymetazolineAlpha-2B adrenergic receptortarget
DB00935OxymetazolineAlpha-1B adrenergic receptortarget
DB00935OxymetazolineAlpha-1D adrenergic receptortarget
DB00988DopamineDopamine D1 receptortarget
DB00988DopamineDopamine beta-hydroxylasetarget
DB00988DopamineAmine oxidase [flavin-containing] Aenzyme
DB00988DopamineAmine oxidase [flavin-containing] Benzyme
DB00988DopamineCatechol O-methyltransferaseenzyme
DB00988DopamineSolute carrier family 22 member 2transporter
DB00988DopamineSolute carrier family 22 member 1transporter
DB00988DopamineSolute carrier family 22 member 3transporter
DB00988DopamineSolute carrier family 22 member 5transporter
DB00988DopaminePOU domain, class 5, transcription factor 1transporter
DB00988DopamineDopamine D5 receptortarget
DB00988DopamineDopamine D2 receptortarget
DB00988DopamineDopamine D3 receptortarget
DB00988DopamineDopamine D4 receptortarget
DB00988DopamineSodium-dependent dopamine transportertarget
DB00988DopamineDopamine beta-hydroxylaseenzyme
DB00988Dopamine5-hydroxytryptamine receptor 1Atarget
DB00988Dopamine5-hydroxytryptamine receptor 7target
DB00988DopamineD(1) dopamine receptortarget
DB00988DopamineSodium-dependent noradrenaline transportertarget
DB00988DopamineSodium-dependent serotonin transportertarget
DB00988Dopamine5-hydroxytryptamine receptor 3Atarget
DB00988Dopamine5-hydroxytryptamine receptor 3Btarget
DB00988DopamineSuperoxide dismutase [Cu-Zn]target
DB00988DopamineSynaptic vesicular amine transportertarget
DB01064IsoprenalineBeta-1 adrenergic receptortarget
DB01064IsoprenalineBeta-2 adrenergic receptortarget
DB01064IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit alphatarget
DB01064IsoprenalineBeta-3 adrenergic receptortarget
DB01064IsoprenalineMitogen-activated protein kinase 1target
DB01064IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit betatarget
DB01064IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit gammatarget
DB01064IsoprenalineCytochrome P450 1A1enzyme
DB01064IsoprenalineCAMP phosphodiesterasetarget
DB01064IsoprenalineSuperoxide dismutase [Cu-Zn]target
DB01193AcebutololBeta-1 adrenergic receptortarget
DB01193AcebutololCytochrome P450 2D6enzyme
DB01193AcebutololBeta-2 adrenergic receptortarget
DB01193AcebutololP-glycoprotein 1transporter
DB01288FenoterolBeta-2 adrenergic receptortarget
DB01288FenoterolBeta-1 adrenergic receptortarget
DB01288FenoterolBeta-3 adrenergic receptortarget
DB01364EphedrineAcetylcholinesterasetarget
DB01364EphedrineAlpha-1A adrenergic receptortarget
DB01364EphedrineSodium-dependent noradrenaline transportertarget
DB01364EphedrineSynaptic vesicular amine transportertarget
DB01364EphedrineCholinesteraseenzyme
DB01365MephentermineAlpha adrenergic receptortarget
DB01365MephentermineBeta adrenergic receptortarget
DB01366ProcaterolBeta-2 adrenergic receptortarget
DB01407ClenbuterolBeta-2 adrenergic receptortarget
DB01407ClenbuterolBeta-nerve growth factortarget
DB01407ClenbuterolTumor necrosis factortarget
DB01407ClenbuterolBeta-1 adrenergic receptortarget
DB01407ClenbuterolBeta-3 adrenergic receptortarget
DB01407ClenbuterolCytochrome P450 1A1enzyme
DB01577MetamfetamineCytochrome P450 2D6enzyme
DB01577MetamfetamineSolute carrier family 22 member 3transporter
DB01577MetamfetamineSolute carrier family 22 member 5transporter
DB01577MetamfetamineSodium-dependent dopamine transportertarget
DB01577MetamfetamineSynaptic vesicular amine transportertarget
DB01577MetamfetamineTrace amine-associated receptor 1target
DB01577MetamfetamineSodium-dependent serotonin transportertarget
DB01577MetamfetamineSodium-dependent noradrenaline transportertarget
DB01577MetamfetamineChromaffin granule amine transportertarget
DB01577MetamfetamineAmine oxidase [flavin-containing] Atarget
DB01577MetamfetamineAmine oxidase [flavin-containing] Btarget
DB01577MetamfetamineAlpha-2A adrenergic receptortarget
DB01577MetamfetamineAlpha-2B adrenergic receptortarget
DB01577MetamfetamineAlpha-2C adrenergic receptortarget
DB04846CeliprololBeta-1 adrenergic receptortarget
DB04846CeliprololBeta-2 adrenergic receptortarget
DB04846CeliprololBeta-3 adrenergic receptortarget
DB04846CeliprololAlpha-2A adrenergic receptortarget
DB04846CeliprololAlpha-2B adrenergic receptortarget
DB04846CeliprololAlpha-2C adrenergic receptortarget
DB04846CeliprololCytochrome P450 2D6enzyme
DB06152NylidrinCatechol O-methyltransferaseenzyme
DB06152NylidrinVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB06152NylidrinInterferon alpha/beta receptor 2target
DB06152NylidrinCytochrome P450 3A4enzyme
DB06764TetryzolineAlpha-1A adrenergic receptortarget
DB08841TyramineSolute carrier family 22 member 3transporter
DB09203SynephrineAlpha-1 adrenergic receptorstarget
DB11124RacepinephrineAlpha-1A adrenergic receptortarget
DB11124RacepinephrineAlpha-1B adrenergic receptortarget
DB11124RacepinephrineAlpha-2A adrenergic receptortarget
DB11124RacepinephrineAlpha-2B adrenergic receptortarget
DB11124RacepinephrineAlpha-2C adrenergic receptortarget
DB11124RacepinephrineBeta-1 adrenergic receptortarget
DB11124RacepinephrineBeta-2 adrenergic receptortarget
DB11124RacepinephrineAlpha-1D adrenergic receptortarget
DB11124RacepinephrineBeta-3 adrenergic receptortarget
DB12752BucindololCytochrome P450 2D6enzyme
DB13757EpanololCytochrome P450 2D6enzyme
DB00852PseudoephedrineAlpha-1A adrenergic receptortarget
DB00852PseudoephedrineAlpha-2A adrenergic receptortarget
DB00852PseudoephedrineBeta-2 adrenergic receptortarget
DB00852PseudoephedrineAmine oxidase [flavin-containing] Aenzyme
DB00852PseudoephedrineBeta-1 adrenergic receptortarget
DB00852PseudoephedrineSodium-dependent dopamine transportertarget
DB00852PseudoephedrineSodium-dependent noradrenaline transportertarget
DB00852PseudoephedrineSodium-dependent serotonin transportertarget
DB00852PseudoephedrineNuclear factor of activated T-cells, cytoplasmic 1target
DB00852PseudoephedrineTumor necrosis factortarget
DB00852PseudoephedrineNuclear factor NF-kappa-B p105 subunittarget
DB00852Pseudoephedrineactivator protein 1target
DB00852PseudoephedrineInterleukin-2target
DB00937DiethylpropionSodium-dependent noradrenaline transportertarget
DB00937DiethylpropionSodium-dependent dopamine transportertarget
DB01255LisdexamfetamineCytochrome P450 2D6enzyme
DB01255LisdexamfetamineSolute carrier family 15 member 1transporter
DB01255LisdexamfetamineTrace amine-associated receptor 1target
DB01576DextroamphetamineAlpha-1A adrenergic receptortarget
DB01576DextroamphetamineAlpha-1B adrenergic receptortarget
DB01576DextroamphetamineSodium-dependent dopamine transportertarget
DB01576DextroamphetamineSodium-dependent noradrenaline transportertarget
DB01576DextroamphetamineSynaptic vesicular amine transportertarget
DB01576DextroamphetamineTrace amine-associated receptor 1target
DB01576DextroamphetamineCytochrome P450 2D6enzyme
DB01576DextroamphetaminePrimary amine oxidaseenzyme
DB01576DextroamphetamineSodium-dependent dopamine transportertransporter
DB01442MMDA5-hydroxytryptamine receptor 2Atarget
DB01442MMDASodium-dependent serotonin transportertarget
DB01442MMDASodium-dependent dopamine transportertarget
DB01442MMDAChromaffin granule amine transportertarget
DB01442MMDASynaptic vesicular amine transportertarget
DB01442MMDAAmine oxidase [flavin-containing] Atarget
DB01442MMDAAmine oxidase [flavin-containing] Btarget
DB01442MMDASodium-dependent noradrenaline transportertarget
DB01454MidomafetamineSodium-dependent serotonin transportertarget
DB01454MidomafetamineSynaptic vesicular amine transportertarget
DB01454MidomafetamineSodium-dependent dopamine transportertarget
DB01454Midomafetamine5-hydroxytryptamine receptor 2Atarget
DB01454Midomafetamine5-hydroxytryptamine receptor 2Btarget
DB01454Midomafetamine5-hydroxytryptamine receptor 2Ctarget
DB01454MidomafetamineSodium-dependent noradrenaline transportertarget
DB01454MidomafetamineSodium-dependent noradrenaline transportertransporter
DB01454MidomafetamineSodium-dependent dopamine transportertransporter
DB01454MidomafetamineSodium-dependent serotonin transportertransporter
DB01454MidomafetamineCytochrome P450 2D6enzyme
DB139402,5-Dimethoxy-4-ethylthioamphetamine5-hydroxytryptamine receptor 2Atarget
DB139402,5-Dimethoxy-4-ethylthioamphetamine5-hydroxytryptamine receptor 2Ctarget