Pneumonia, Pneumocystis

Also known as: Pneumocystis pneumonia / Pneumonias, Pneumocystis / Pneumocystosis / Pneumocystis jiroveci pneumonia / PCP / Pneumonia due to Pneumocystis carinii / Pneumocystis jirovecii pneumonia / Interstitial plasma cell pneumonia / Pneumocystis carinii pneumonia

DrugDrug NameDrug Description
DB01190ClindamycinClindamycin is a semisynthetic lincosamide antibiotic that has largely replaced lincomycin due to an improved side effect profile. Clindamycin inhibits bacterial protein synthesis by binding to bacterial 50S ribosomal subunits. It may be bacteriostatic or bactericidal depending on the organism and drug concentration.
DB01087PrimaquineAn aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
DB00440TrimethoprimA pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to pyrimethamine. The interference with folic acid metabolism may cause a depression of hematopoiesis. It is potentiated by sulfonamides and the trimethoprim-sulfamethoxazole combination is the form most often used. It is sometimes used alone as an antimalarial. Trimethoprim resistance has been reported. [PubChem]
DrugDrug NamePhaseStatusCount
DB01015Sulfamethoxazole2 / 3Unknown Status1
DB00440Trimethoprim2 / 3Unknown Status1
DB00520CaspofunginNot AvailableRecruiting1
DB00959MethylprednisoloneNot AvailableRecruiting1