Pertussis

Also known as: Whooping cough due to Bordetella pertussis / Whooping Cough / Whooping cough due to bordetella pertussis (B. pertussis)

DrugDrug NameDrug Description
DB00415AmpicillinAmpicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
DB10991Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated)Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) is a vaccine that is used in the prophylaxis of Pertussis (whooping cough), which is caused by a small Gram-negative coccobacillus that infects the mucosal layers of the human respiratory tract.
DB01211ClarithromycinClarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process. Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration.
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection. It is used for active immunization of children 7 years of age or older, and adults, for prevention of tetanus. The toxoid in the Clostridium tetani culture is grown and detoxified followed by purification via ammonium sulfate filtration and precipation.
DB00199ErythromycinErythromycin is an antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the _macrolide_ group of antibiotics [FDA label]. It was originally discovered in 1952. Erythromycin is widely used for treating a variety of infections, including those caused by gram-positive bacteria, gram-negative bacteria and many other organisms [L5245], [FDA label].
DrugDrug NameTargetType
DB00415AmpicillinSerum albumincarrier
DB00415AmpicillinSolute carrier family 22 member 5transporter
DB00415AmpicillinSolute carrier family 15 member 1transporter
DB00415AmpicillinSolute carrier family 15 member 2transporter
DB00415AmpicillinPenicillin-binding protein 2atarget
DB00415AmpicillinPenicillin-binding protein 1btarget
DB00415AmpicillinPenicillin-binding protein 3target
DB00415AmpicillinPenicillin-binding protein 1Atarget
DB00415AmpicillinPenicillin-binding protein 2Btarget
DB00415AmpicillinMonocarboxylate transporter 1transporter
DB00415AmpicillinSolute carrier family 15 member 1target
DB00415AmpicillinSolute carrier family 15 member 2target
DB00415AmpicillinAngiopoietin-1 receptortarget
DB01211Clarithromycin50S ribosomal protein L10target
DB01211ClarithromycinCytochrome P450 3A4enzyme
DB01211ClarithromycinCytochrome P450 2C19enzyme
DB01211ClarithromycinCytochrome P450 3A5enzyme
DB01211ClarithromycinCytochrome P450 3A7enzyme
DB01211ClarithromycinMultidrug resistance protein 1transporter
DB01211ClarithromycinSolute carrier family 22 member 7transporter
DB01211ClarithromycinPotassium voltage-gated channel subfamily H member 2target
DB01211ClarithromycinSolute carrier organic anion transporter family member 1B1target
DB01211ClarithromycinSolute carrier organic anion transporter family member 1B3target
DB01211ClarithromycinBile salt export pumptransporter
DB00199Erythromycin23S rRNAtarget
DB00199ErythromycinCytochrome P450 3A4enzyme
DB00199ErythromycinCytochrome P450 3A7enzyme
DB00199ErythromycinMultidrug resistance protein 1transporter
DB00199ErythromycinSolute carrier organic anion transporter family member 1B1transporter
DB00199ErythromycinMotilin receptortarget
DB00199ErythromycinPotassium voltage-gated channel subfamily H member 2target
DB00199ErythromycinCytochrome P450 3A5enzyme
DB00199ErythromycinSolute carrier organic anion transporter family member 1B3transporter
DB00199ErythromycinBile salt export pumptransporter
DB00199ErythromycinBacterial 50S Ribosomal Subunittarget
DB00199ErythromycinCanalicular multispecific organic anion transporter 1transporter
DB00199ErythromycinSolute carrier organic anion transporter family member 1A2transporter
DrugDrug NamePhaseStatusCount
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)1Completed1
DB10788Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated)2Completed1
DB10790Bordetella pertussis fimbriae 2/3 antigen2Completed1
DB10789Bordetella pertussis pertactin antigen2Completed1
DB10787Bordetella pertussis toxoid antigen (glutaraldehyde inactivated)2Completed1
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)2Active Not Recruiting1
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)2Completed2
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)2Recruiting1
DB10584Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)2Completed1
DB10076Haemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen2Completed1
DB11627Hepatitis B Vaccine (Recombinant)2Completed2
DB13890Meningococcal polysaccharide vaccine group C2Completed1
DB10798Neisseria meningitidis group a capsular polysaccharide diphtheria toxoid conjugate antigen2Completed1
DB10795Poliovirus type 1 antigen (formaldehyde inactivated)2Completed2
DB10796Poliovirus type 2 antigen (formaldehyde inactivated)2Completed1
DB10797Poliovirus type 3 antigen (formaldehyde inactivated)2Completed1
DB10788Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated)3Completed3
DB10790Bordetella pertussis fimbriae 2/3 antigen3Completed1
DB10789Bordetella pertussis pertactin antigen3Completed1
DB10787Bordetella pertussis toxoid antigen (glutaraldehyde inactivated)3Completed1
DB11121Chloroxylenol3Completed1
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)3Completed8
DB10584Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)3Completed4
DB10076Haemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen3Active Not Recruiting1
DB10076Haemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen3Completed2
DB10990Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen3Completed10
DB11627Hepatitis B Vaccine (Recombinant)3Completed2
DB14618INFLUENZA A VIRUS A/BRISBANE/59/2007(H1N1) HEMAGGLUTININ ANTIGEN (FORMALDEHYDE INACTIVATED)3Completed1
DB14617INFLUENZA A VIRUS A/URUGUAY/716/2007(H3N2) HEMAGGLUTININ ANTIGEN (FORMALDEHYDE INACTIVATED)3Completed1
DB14385Influenza b virus b/brisbane/60/2008 hemagglutinin antigen (formaldehyde inactivated)3Completed1
DB10315Measles virus strain enders' attenuated edmonston live antigen3Completed1
DB10795Poliovirus type 1 antigen (formaldehyde inactivated)3Completed2
DB10796Poliovirus type 2 antigen (formaldehyde inactivated)3Completed1
DB10797Poliovirus type 3 antigen (formaldehyde inactivated)3Completed1
DB10276Rotavirus Vaccine3Completed1
DB10286Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria crm197 protein conjugate antigen3Completed2
DB10318Varicella Zoster Vaccine (Live/Attenuated)3Completed1
DB09145Water3Completed1
DB10788Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated)4Completed1
DB10790Bordetella pertussis fimbriae 2/3 antigen4Completed1
DB10789Bordetella pertussis pertactin antigen4Completed1
DB10787Bordetella pertussis toxoid antigen (glutaraldehyde inactivated)4Completed1
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)4Completed6
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)4Recruiting1
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)4Terminated1
DB10584Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)4Completed2
DB10076Haemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigen4Completed1
DB10989Hepatitis A Vaccine4Terminated1
DB10061Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine4Completed1
DB10798Neisseria meningitidis group a capsular polysaccharide diphtheria toxoid conjugate antigen4Completed2
DB15274Pertussis vaccine4Active Not Recruiting1
DB15274Pertussis vaccine4Completed1
DB10795Poliovirus type 1 antigen (formaldehyde inactivated)4Completed1
DB10796Poliovirus type 2 antigen (formaldehyde inactivated)4Completed1
DB10797Poliovirus type 3 antigen (formaldehyde inactivated)4Completed1
DB10788Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated)Not AvailableCompleted2
DB10790Bordetella pertussis fimbriae 2/3 antigenNot AvailableCompleted2
DB10789Bordetella pertussis pertactin antigenNot AvailableCompleted2
DB10787Bordetella pertussis toxoid antigen (glutaraldehyde inactivated)Not AvailableCompleted2
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)Not AvailableCompleted2
DB10584Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)Not AvailableCompleted2
DB10342Haemophilus influenzae type b capsular polysaccharide meningococcal outer membrane protein conjugate antigenNot AvailableActive Not Recruiting1
DB10076Haemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigenNot AvailableActive Not Recruiting1
DB10076Haemophilus influenzae type b strain 1482 capsular polysaccharide tetanus toxoid conjugate antigenNot AvailableCompleted2
DB11627Hepatitis B Vaccine (Recombinant)Not AvailableCompleted1
DB10795Poliovirus type 1 antigen (formaldehyde inactivated)Not AvailableCompleted2
DB10796Poliovirus type 2 antigen (formaldehyde inactivated)Not AvailableCompleted2
DB10797Poliovirus type 3 antigen (formaldehyde inactivated)Not AvailableCompleted2