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Displaying drugs 26 - 50 of 4906 in total
Linezolid
Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most isolates of streptococci. Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein synthesis - more specifically,...
Approved
Investigational
Matched Synonyms: … N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide …
Azacitidine
Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Synonyms: … 4-amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one …
CVac
Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …
Dimethyl sulfoxide
A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during cryopreservation. Dimethyl sulfoxide shows a range of pharmacological activity including...
Approved
Vet approved
Matched Synonyms: … S(O)Me2 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Asparagine
A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from aspartic acid and ammonia by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
Approved
Investigational
Nutraceutical
Matched Synonyms: … (S)-Asparagine ... (S)-2-amino-3-carbamoylpropanoic acid …
Pidolic acid
Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various chemical pathways [A32991, L2729]. Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism...
Approved
Investigational
Matched Synonyms: … (S)-pyroglutamic acid ... (S)-(−)-2-pyrrolidone-5-carboxylic acid …
Matched Description: … is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or ... Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism ... There are currently little to no medicines available that are clinically approved or marketed for employing …
Matched Description: … is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or ... Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism ... There are currently little to no medicines available that are clinically approved or marketed for employing …
Ertapenem
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem …
Quinidine
Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Synonyms: … (S)-(6-Methoxyquinolin-4-yl)((2R,5R)-5-vinylquinuclidin-2-yl)methanol ... (S)-(6-Methoxy-quinolin-4-yl)-((2R,5R)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol …
Matched Iupac: … (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Iupac: … (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Idelalisib
Idelalisib is a phosphoinositide 3-kinase inhibitor indicated in the treatment of chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). For the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with rituximab in patients for whom rituximab...
Approved
Matched Synonyms: … 5-Fluoro-3-phenyl-2-((S)-1-(9H-purin-6-ylamino)-propyl)-3H-quinazolin-4-one …
Propofol
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness,...
Approved
Investigational
Vet approved
Matched Description: … procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or …
Matched Mixtures name: … Anesthesia S/I-60 ... Anesthesia S/I-40 ... Anesthesia S/I-50 …
Matched Products: … Injection or Infusion 1% w/v) ... FRESOFOL 2% MCT/LCT EMULSION FOR INJECTION OR INFUSION ... Recofol N 10mg/ml Emulsion for injection or infusion …
Matched Mixtures name: … Anesthesia S/I-60 ... Anesthesia S/I-40 ... Anesthesia S/I-50 …
Matched Products: … Injection or Infusion 1% w/v) ... FRESOFOL 2% MCT/LCT EMULSION FOR INJECTION OR INFUSION ... Recofol N 10mg/ml Emulsion for injection or infusion …
Carglumic acid
Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death. Carglumic acid was...
Approved
Matched Synonyms: … (S)-2-ureidopentanedioic acid …
Methyldopa
Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug requires biotransformation to an active metabolite for therapeutic effects. Methyldopa works by binding to alpha(α)-2 adrenergic receptors as an agonist, leading...
Approved
Matched Synonyms: … (S)-(-)-alpha-Methyldopa …
Matched Description: … Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. ... better-tolerated antihypertensive agents;[A231784] however, it is still used as monotherapy [L32614] or …
Matched Description: … Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. ... better-tolerated antihypertensive agents;[A231784] however, it is still used as monotherapy [L32614] or …
Fibrinogen human
Fibrinogen concentrate (human) is a hematological agent. It works by replacing a certain protein in the blood that helps with blood clotting. Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. It is a physiological substrate for three enzymes: plasmin, factor XIIIa and...
Approved
Matched Mixtures name: … TISSEEL FIBRIN SEALANT VH S/D (FROZEN) …
Matched Products: … HAEMOCOMPLETTAN P POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL ... Fibryga 1g Powder and Solvent for Solution for Injection or Infusion ... FIBRYGA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL …
Matched Products: … HAEMOCOMPLETTAN P POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL ... Fibryga 1g Powder and Solvent for Solution for Injection or Infusion ... FIBRYGA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION OR INFUSION 1G/VIAL …
Lovastatin
Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of Aspergillus terreus. Originally named Mevinolin, lovastatin belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid...
Approved
Investigational
Matched Synonyms: … 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl (S) …
Matched Description: … The clear evidence of the benefit of statin use coupled with very minimal side effects or long term effects ... all-cause mortality including fatal and non-fatal CVD as well as the need for surgical revascularization or ... revascularization, and coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or …
Matched Description: … The clear evidence of the benefit of statin use coupled with very minimal side effects or long term effects ... all-cause mortality including fatal and non-fatal CVD as well as the need for surgical revascularization or ... revascularization, and coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or …
Amikacin
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Synonyms: … -D-GLUCOPYRANOSYL-(1->4))-N(SUP 1)-(4-AMINO-2-HYDROXY-1-OXOBUTYL)-2-DEOXY-, (S)- …
Matched Description: … [L4680] Several forms of amikacin are used currently, including an intravenous (IV) or intramuscular …
Matched Products: … AMIKASON´S …
Matched Description: … [L4680] Several forms of amikacin are used currently, including an intravenous (IV) or intramuscular …
Matched Products: … AMIKASON´S …
Dermatophagoides farinae
Dermatophagoides farinae extracts are sterile solutions used for intradermal testing or subcutaneous immunotherapy. This combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Approved
Matched Description: … Dermatophagoides farinae extracts are sterile solutions used for intradermal testing or subcutaneous …
Matched Products: … Standardized Mite, Dermatophagoides farinae, Scratch or Bulk, 30000 AU per mL …
Matched Products: … Standardized Mite, Dermatophagoides farinae, Scratch or Bulk, 30000 AU per mL …
Dermatophagoides pteronyssinus
Dermatophagoides pteronyssinus extracts are sterile solutions used for intradermal testing or subcutaneous immunotherapy. This combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Approved
Matched Description: … Dermatophagoides pteronyssinus extracts are sterile solutions used for intradermal testing or subcutaneous …
Matched Products: … Standardized Mite, Dermatophagoides pteronyssinus, Scratch or Bulk, 30000 AU per mL …
Matched Products: … Standardized Mite, Dermatophagoides pteronyssinus, Scratch or Bulk, 30000 AU per mL …
Betaxolol
A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Approved
Investigational
Matched Products: … Betoptic S ... BETOPTIC S ... Betoptic S Augensuspension …
Benzoic acid
A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads...
Approved
Investigational
Matched Mixtures name: … WHITFIELD`S OINTMENT ... WHITFIELD`S OINTMENT …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … S Panax Mist ... S Panax Mist for Refill ... S Panax All In One Mist …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … S Panax Mist ... S Panax Mist for Refill ... S Panax All In One Mist …
Elapegademase
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … (74-SERINE (C>S),245-THREONINE (A>T))BOS TAURUS ADENOSINE DEAMINASE (BOVINE ADENOSINE AMINOHYDROLASE, …
Daptomycin
Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Products: … DAPTOCCORD 500 POWDER FOR SOLUTION FOR INJECTION OR INFUSION 500 MG/VIAL …
Ceftriaxone
Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Description: … Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins ... relatively safe adverse effect profile, and its long half-life which allows for the convenience of daily or …
Matched Products: … MEDAXONE POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1 G/VIAL ... MEDAXONE POWDER FOR SOLUTION FOR INJECTION OR INFUSION 2 G/VIAL …
Matched Products: … MEDAXONE POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1 G/VIAL ... MEDAXONE POWDER FOR SOLUTION FOR INJECTION OR INFUSION 2 G/VIAL …
Valproic acid
Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century. In 1963, a serendipitous discovery was made by George Carraz during his investigations into...
Approved
Investigational
Matched Description: … 1881 by Beverly S. ... Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in …
Matched Products: … TRANKITEC-S ... ATEMPERATOR S ... SODIUM VALPROATE WOCKHARDT SOLUTION FOR INJECTION OR INFUSION 100mg/ml …
Matched Products: … TRANKITEC-S ... ATEMPERATOR S ... SODIUM VALPROATE WOCKHARDT SOLUTION FOR INJECTION OR INFUSION 100mg/ml …
Acebutolol
A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Approved
Investigational
Matched Products: … Novo-acebutolol (type S) ... Mylan-acebutolol (type S) …
Displaying drugs 26 - 50 of 4906 in total