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Displaying drugs 101 - 125 of 8058 in total

Bromotheophylline

Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline. From this mixture, bromotheophylline acts as a weak diuretic that has been used along with some analgesics to relieve the symptoms of premenstrual syndrome. Bromotheophylline is categorized on the FDA as a drug substance with an inactive...
Approved
Matched Description: … Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline ... bromotheophylline acts as a weak diuretic that has been used along with some analgesics to relieve the symptoms of …
Matched Categories: … combinations of xanthines …

Carindacillin

Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of carbenicillin marketed by Pfizer as Geocillin. It is no longer marketed in the United States.
Approved
Investigational
Matched Description: … Carindacillin or Carbenicillin isdanyl was an oral penicillin prodrug of [carbenicillin] marketed by …
Matched Categories: … combinations of penicillins …

Flortaucipir F-18

Flortaucipir F-18, also known as 18F-T807 and 18F-AV-1451, is a small indole molecule synthesized with a radioactive fluorine isotope. It is used as a marker in positron emission tomography (PET) imaging of patients suspected of having Alzheimer's disease. After crossing the blood-brain barrier, flortaucipir F-18 binds to aggregated tau protein,...
Approved
Investigational
Matched Description: … of having Alzheimer's disease. ... [A203933] It is used as a marker in positron emission tomography (PET) imaging of patients suspected ... After crossing the blood-brain barrier, flortaucipir F-18 binds to aggregated tau protein, a hallmark of …
Matched Categories: … Diagnostic Uses of Chemicals …

Alendronic acid

Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Description: … Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of ... It functions by preventing resorption of bone[FDA Label][A959]. …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Mezlocillin

Semisynthetic ampicillin-derived acylureido penicillin. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections.
Approved
Investigational
Matched Categories: … combinations of penicillins …

Econazole

A broad spectrum antimycotic with some action against Gram positive bacteria. It is used topically in dermatomycoses also orally and parenterally.
Approved
Matched Categories: … combinations of imidazole derivatives ... Metabolic Side Effects of Drugs and Substances …

Bumetanide

Bumetanide is a sulfamyl diuretic.
Approved
Matched Categories: … combinations of sulfonamides ... Increased Diuresis at Loop of Henle …

Gadoteridol

Gadoteridol is a macrocyclic nonionic gadolinium that provides contrast enhancement of the brain, spine, and surrounding tissues, resulting in improved visualization (compared with unenhanced MRI) of lesions with abnormal vascularity or those thought to disrupt the normal blood-brain barrier.[A263076,A263081,L49871] It was 1 of the 3 macrocyclic gadolinium-based contrast agents (GBCAs)...
Approved
Investigational
Matched Description: … Gadoteridol is a macrocyclic nonionic gadolinium that provides contrast enhancement of the brain, spine ... , and surrounding tissues, resulting in improved visualization (compared with unenhanced MRI) of lesions ... [A263076,A263081,L49871] It was 1 of the 3 macrocyclic gadolinium-based contrast agents (GBCAs) that …
Matched Categories: … Diagnostic Uses of Chemicals …

Dienestrol

Dienestrol is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist. Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy. Using or applying an estrogen relieves or lessens: dryness and soreness in the vagina, itching, redness, or soreness of...
Approved
Investigational
Matched Description: … the vagina (atrophic vaginitis), and inflammation of the urethra (atrophic urethritis). ... an estrogen relieves or lessens: dryness and soreness in the vagina, itching, redness, or soreness of ... are treated with vaginal estrogens include a genital skin condition (vulvar atrophy), inflammation of …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Pyrazinamide

A pyrazine that is used therapeutically as an antitubercular agent.
Approved
Investigational
Matched Categories: … Drugs for Treatment of Tuberculosis …

Cycloserine

Antibiotic substance produced by Streptomyces garyphalus.
Approved
Matched Categories: … Drugs for Treatment of Tuberculosis …

Cyclothiazide

As a diuretic, cyclothiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of sodium, chloride, and water. Thiazides like cyclothiazide also inhibit sodium ion transport across the renal tubular epithelium through binding to the thiazide sensitive sodium-chloride transporter....
Approved
Matched Description: … the effectiveness of other antihypertensive drugs in the more severe forms of hypertension. ... reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of ... The antihypertensive mechanism of cyclothiazide is less well understood although it may be mediated through …
Matched Categories: … combinations of sulfonamides …

Dezocine

Dezocine is a partial opiate drug and is used for pain management. Dezocine is a very effective alternative to fentanyl when administered during outpatient laparoscopy, although is associated with an increased incidence of postoperative nausea.
Approved
Investigational
Matched Description: … when administered during outpatient laparoscopy, although is associated with an increased incidence of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Lonapegsomatropin

Lonapegsomatropin, also known as TransCon hGH or ACP 001, is a methoxypegylated prodrug of human growth hormone (somatropin) indicated for the treatment of children 1 year and older, weighing at least 11.5 kg, with growth failure due to insufficient growth hormone secretion.[A237605,L36380,L36405] Unlike somatropin, which requires daily dosing, lonapegsomatropin can...
Approved
Investigational
Matched Description: … Lonapegsomatropin, also known as TransCon hGH or ACP 001, is a methoxypegylated prodrug of human growth ... hormone ([somatropin]) indicated for the treatment of children 1 year and older, weighing at least 11.5 …

Chlorpheniramine

A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Approved
Matched Description: … One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and …
Matched Mixtures name: … Hot Lemon Relief for Symptoms Of Cough, Cold and Flu ... Hot Lemon Relief for Symptoms Of Cough, Cold and Flu Extra Strength ... Hot Lemon Relief for Symptoms Of Cough, Cold and Flu Ultra Strength …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Medrogestone

Medrogestone (INN), also known as 6,17α-dimethyl-6-dehydroprogesterone, is a progestational agent derived from 17-methylprogesterone. It was conceived as an alternative for an orally effective contraceptive option. It was developed by Ayerst, approved in Canada in 1969 and its current status is cancelled post-marketing. It was never approved by the FDA.
Approved
Withdrawn
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Acetyl sulfisoxazole

Sulfisoxazole acetyl is an ester of sulfisoxazole, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial activity. Sulfisoxazole acetyl competes with PABA for the bacterial enzyme, dihydropteroate synthase, preventing the incorporation of PABA into dihydrofolic acid, which is the precursor of folic acid. This process causes...
Approved
Vet approved
Matched Description: … This process causes an inhibition of bacterial folic acid synthesis and de novo synthesis of purines ... of para-aminobenzoic acid (PABA) with antibacterial activity. ... PABA into dihydrofolic acid, which is the precursor of folic acid. …
Matched Categories: … combinations of sulfonamides …

Ribavirin

Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. It is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. HCV is a single-stranded RNA virus that is categorized...
Approved
Matched Description: … Combination therapy of ribavirin and [DB00008] results in the SVR of 44% in patients with genotype 1 ... Additionally, including ribavirin in the regimen can increase the risk of anemia. ... Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of …
Matched Categories: … Antivirals for treatment of HCV infections …

Pitavastatin

Pitavastatin, also known as the brand name product Livalo, is a lipid-lowering drug belonging to the statin class of medications. By inhibiting the endogenous production of cholesterol within the liver, statins lower abnormal cholesterol and lipid levels and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively...
Approved
Matched Description: … studies to significantly reduce the risk of development of CVD and all-cause mortality. ... and for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes ... This is the third step in a sequence of metabolic reactions involved in the production of several compounds …

Butalbital

Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. It is a short-to-intermediate acting member of barbiturates that exhibit muscle-relaxing and anti-anxiety properties that produce central nervous system (CNS) depression that ranges from...
Approved
Illicit
Matched Description: … [A177754] Butalbital has a low degree of selectivity and a narrow therapeutic index. ... Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens ... It is a short-to-intermediate acting member of barbiturates that exhibit muscle-relaxing and anti-anxiety …
Matched Categories: … combinations of barbiturates …

Diethylpropion

A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
Approved
Illicit
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Ioxitalamic acid

Ioxitalamate is an ionic iodinated contrast medium. It is a first-generation contrast media formed by an ionic monomer with a high osmolarity of 1500-1800 mOsm/kg. Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Liebel-Flarshem Canada Inc and approved by Health Canada in 1995. Until the...
Approved
Matched Description: … [A27209] It is a first-generation contrast media formed by an ionic monomer with a high osmolarity of ... [A33006] Ioxitalamic acid in the salt forms of sodium and meglumine was developed by Liebel-Flarshem …
Matched Categories: … Diagnostic Uses of Chemicals …

Follitropin

Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78...
Approved
Matched Description: … Structural analysis shows that the amino acid sequence of follitropin beta is identical to that of natural ... Follitropin is important in the development of follicles produced by the ovaries. ... Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Tryptophan

An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit...
Approved
Nutraceutical
Withdrawn
Matched Description: … It is a precursor of indole alkaloids in plants. ... It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Silver sulfadiazine

Silver sulfadiazine is a sulfa derivative topical antibacterial used primarily on second- and third-degree burns.
Approved
Vet approved
Matched Categories: … combinations of sulfonamides …
Displaying drugs 101 - 125 of 8058 in total