Displaying drugs 126 - 150 of 10565 in total
Glycopyrronium
Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergic medications.[A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the...
Approved
Investigational
Vet approved
Matched Iupac: … 3-[(2-cyclopentyl-2-hydroxy-2-phenylacetyl)oxy]-1,1-dimethylpyrrolidin-1-ium …
Matched Salts cas: … 1624259-25-1 …
Matched Categories: … MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Matched Products: … SEBRALER 50 MCG İNHALASYON TOZU, KAPSÜL, 90 ADET ... PANTHERO NEOHALER 50 MIKROGRAM INHALER KAPSUL, 90 ADET …
Matched Salts cas: … 1624259-25-1 …
Matched Categories: … MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Matched Products: … SEBRALER 50 MCG İNHALASYON TOZU, KAPSÜL, 90 ADET ... PANTHERO NEOHALER 50 MIKROGRAM INHALER KAPSUL, 90 ADET …
Ofloxacin
A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Approved
Matched Synonyms: … 8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic …
Matched Iupac: … 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13), …
Matched Products: … MENEFLOKS IV 200 MG/100 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET …
Matched Iupac: … 7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5(13), …
Matched Products: … MENEFLOKS IV 200 MG/100 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET …
Tipiracil
Tipiracil is a thymidine phosphorylase inhibitor. It is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. The main function of Tipiracil in TAS-102 is to increase trifluridine bioavailability by inhibiting its catabolism. TAS-102 is indicated for the treatment of metastatic colorectal cancer which has been...
Approved
Investigational
Matched Synonyms: … 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrimidinedione ... 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1H-pyrimidine-2,4-dione …
Matched Iupac: … 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … It is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. …
Matched Categories: … MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring ... MATE 1 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … It is used in combination with trifluridine, in a ratio of 1:0.5, to form TAS-102. …
Matched Categories: … MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring ... MATE 1 Substrates with a Narrow Therapeutic Index …
Ximelagatran
Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former. In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-yl]- 2-oxo-ethyl]amino]acetate ... ethyl 2-[[(1R)-1-cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin- …
Matched Iupac: … -1-yl]-2-oxoethyl]amino}acetate ... ethyl 2-{[(1R)-1-cyclohexyl-2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … -1-yl]-2-oxoethyl]amino}acetate ... ethyl 2-{[(1R)-1-cyclohexyl-2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Amylocaine
Despite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes were sought after immediately . Finally, in 1903 the world's first synthetic and non-addictive local anesthetic, amylocaine, was synthesized and patented under the name Forneaucaine by Ernest Fourneau at the Pasteur Institute . Elsewhere in English...
Approved
Withdrawn
Matched Synonyms: … 1-(Dimethylamino)-2-methyl-2-butanol benzoate …
Matched Iupac: … 1-(dimethylamino)-2-methylbutan-2-yl benzoate …
Matched Iupac: … 1-(dimethylamino)-2-methylbutan-2-yl benzoate …
Rizatriptan
Rizatriptan is a second-generation triptan and a selective 5-HT1B and 5-HT1D receptor agonist. Used in the treatment of migraines, rizatriptan was first approved in the US in 1998. Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film formulations.
Approved
Matched Synonyms: … N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine ... N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine …
Matched Iupac: … dimethyl(2-{5-[(1H-1,2,4-triazol-1-yl)methyl]-1H-indol-3-yl}ethyl)amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … dimethyl(2-{5-[(1H-1,2,4-triazol-1-yl)methyl]-1H-indol-3-yl}ethyl)amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Amphetamine
Amphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs. It was previously used for a large variety of conditions and this changed until this point where its use is highly restricted. Amphetamine, with the chemical formula alpha-methylphenethylamine, was discovered in 1910 and first...
Approved
Illicit
Investigational
Matched Synonyms: … 1-phenyl-2-aminopropane ... rac-(2R)-1-phenylpropan-2-amine …
Matched Iupac: … 1-phenylpropan-2-amine …
Matched Iupac: … 1-phenylpropan-2-amine …
Promazine
A phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. It is currently not approved for use in the United States.
Approved
Vet approved
Matched Synonyms: … N-Dimethylamino-1-methylethyl thiodiphenylamine ... N,N-dimethyl-3-(10H-phenothiazin-10-yl)-propan-1-amine …
Matched Salts cas: … 53-60-1 …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists …
Matched Salts cas: … 53-60-1 …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists …
Abacavir
Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. In vivo, abacavir sulfate dissociates to its free base, abacavir.
Approved
Investigational
Matched Synonyms: … {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol …
Matched Iupac: … [(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl]methanol …
Matched Mixtures name: … TRIUMEQ 50 MG/600 MG/300 MG FILM KAPLI TABLET,90 FILM KAPLI TABLET …
Matched Iupac: … [(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl]methanol …
Matched Mixtures name: … TRIUMEQ 50 MG/600 MG/300 MG FILM KAPLI TABLET,90 FILM KAPLI TABLET …
Eslicarbazepine acetate
Eslicarbazepine acetate (ESL) is an anticonvulsant medication approved for use in Europe, the United States and Canada as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy. Eslicarbazepine acetate is a prodrug that is rapidly converted to eslicarbazepine, the primary active metabolite in the body....
Approved
Matched Iupac: … (9S)-2-carbamoyl-2-azatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaen-9-yl acetate …
Matched Products: … ZEBINIX 800MG TABLET, 90 ADET …
Matched Products: … ZEBINIX 800MG TABLET, 90 ADET …
Hetacillin
Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Hetacillin has in vitro activity against gram-positive and gram-negative...
Approved
Vet approved
Withdrawn
Matched Synonyms: … (2S,5R,6R)-6-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo ... 6β-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]penicillanic acid …
Matched Iupac: … (2S,5R,6R)-6-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Iupac: … (2S,5R,6R)-6-[(4R)-2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Dimercaprol
Dimercaprol is a traditional chelating agent developed by British biochemists at Oxford University during World War II. It was developed as an experimental antidote against the arsenic-based poison gas Lewisite. It has been used clinically since 1949 in arsenic, cadmium and mercury poisoning. In addition, it has in the past...
Approved
Matched Synonyms: … 2,3-dimercapto-1-propanol ... 2,3-mercaptopropan-1-ol ... 2,3-dimercaptol-1-propanol …
Matched Iupac: … 2,3-disulfanylpropan-1-ol …
Matched Iupac: … 2,3-disulfanylpropan-1-ol …
Amyl Nitrite
Amyl Nitrite is an antihypertensive medicine. Amyl nitrite is employed medically to treat heart diseases such as angina and to treat cyanide poisoning. Its use as a prescription medicine comes from its ability to lower blood pressure. As an inhalant, it also has psychoactive effect which has led to illegal...
Approved
Matched Synonyms: … 1-nitropentane …
Tegaserod
Novartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C).[L5918,F4229] It was, however, voluntarily withdrawn from widespread use in the US market in 2007 after concerns arose over the possibility that tegaserod could potentially cause...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-(((5-Methoxyindol-3-yl)methylene)amino)-3-pentylguanidine …
Rolitetracycline
A pyrrolidinylmethyl tetracycline.
Approved
Matched Synonyms: … N-(1-Pyrrolidinylmethyl)-tetracycline …
Matched Iupac: … 4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-[(pyrrolidin-1- …
Matched Iupac: … 4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-[(pyrrolidin-1- …
Naratriptan
Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.
Approved
Investigational
Matched Synonyms: … N-methyl-2-(3-(1-methylpiperiden-4-yl)indole-5-yl)ethanesulfonamide ... N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamide …
Matched Iupac: … N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethane-1-sulfonamide …
Matched Salts cas: … 143388-64-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethane-1-sulfonamide …
Matched Salts cas: … 143388-64-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Mesoridazine
A phenothiazine antipsychotic with effects similar to chlorpromazine.
Approved
Investigational
Matched Synonyms: … 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-methylsulfinyl phenothiazine ... 10-(2(1-Methyl-2-piperidyl)ethyl)-2-(methylsulfinyl)phenothiazine ... 2-Methanesulfinyl-10-[2-(1-methyl-piperidin-2-yl)-ethyl]-10H-phenothiazine …
Matched Iupac: … 2-methanesulfinyl-10-[2-(1-methylpiperidin-2-yl)ethyl]-10H-phenothiazine …
Matched Iupac: … 2-methanesulfinyl-10-[2-(1-methylpiperidin-2-yl)ethyl]-10H-phenothiazine …
Glyburide
Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. It is typically given to patients who cannot be managed with the standard first line therapy, metformin. Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels on beta cells, raising intracellular potassium and...
Approved
Matched Synonyms: … 1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea ... 1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea …
Matched Description: … [A183617] Glyburide was granted FDA approval on 1 May 1984. …
Matched Products: … MANINIL 1 ... MANINIL 1 BLISTER …
Matched Description: … [A183617] Glyburide was granted FDA approval on 1 May 1984. …
Matched Products: … MANINIL 1 ... MANINIL 1 BLISTER …
Pravastatin
Pravastatin is the 6-alpha-hydroxy acid form of mevastatin. Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug. This drug was developed by Sankyo Co. Ltd.; however, the first approved...
Approved
Matched Synonyms: … dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(S)-2-methylbutyryl]oxy}-1,2,6,7,8,8a-hexahydro-1- …
Matched Iupac: … 1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1- …
Matched Iupac: … 1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1- …
Mezlocillin
Semisynthetic ampicillin-derived acylureido penicillin. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections.
Approved
Investigational
Matched Synonyms: … ]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... 6β-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanic acid ... (2S,5R,6R)-3,3-dimethyl-6-{[(2R)-2-({[3-(methylsulfonyl)-2-oxoimidazolidin-1-yl]carbonyl}amino)-2-phenylacetyl …
Matched Iupac: … dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-6-[(2R)-2-[(3-methanesulfonyl-2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetamido]-3,3- …
Matched Salts cas: … 80495-46-1 …
Matched Iupac: … dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-6-[(2R)-2-[(3-methanesulfonyl-2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetamido]-3,3- …
Matched Salts cas: … 80495-46-1 …
Celecoxib
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in...
Approved
Investigational
Matched Synonyms: … p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide …
Matched Iupac: … 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide …
Matched Iupac: … 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide …
Cupric sulfate
Cupric sulfate is a salt created by treating cupric oxide with sulfuric acid. This forms as large, bright blue crystals containing five molecules of water (CuSO4∙5H2O) and is also known as blue vitriol. The anhydrous salt is created by heating the hydrate to 150 °C (300 °F). Cupric sulfate is...
Approved
Matched Synonyms: … Copper sulfate (1:1) …
Matched Description: … The average daily intake of copper in the USA is approximately 1 mg Cu with the diet being a primary …
Matched Description: … The average daily intake of copper in the USA is approximately 1 mg Cu with the diet being a primary …
Cefotaxime
Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Approved
Matched Synonyms: … (6R,7R,Z)-3-(acetoxymethyl)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-aza-bicyclo ... -3-(acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1- ... (6R,7R)-3-Acetoxymethyl-7-{2-(2-amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-8-oxo-5-thia-1- …
Matched Iupac: … -3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1- …
Matched Mixtures name: … SEFOTAK 1 G IM ENJEKSİYONLUK TOZ İÇEREN FLAKON, 1 ADET …
Matched Products: … SEFAGEN 1 G IM ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 FLAKON + 1 AMPUL ... TAXEGRAM 1 ... CLATAX 1 …
Matched Iupac: … -3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1- …
Matched Mixtures name: … SEFOTAK 1 G IM ENJEKSİYONLUK TOZ İÇEREN FLAKON, 1 ADET …
Matched Products: … SEFAGEN 1 G IM ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 FLAKON + 1 AMPUL ... TAXEGRAM 1 ... CLATAX 1 …
Cetrimonium
Cetrimonium is a quaternary ammonium cation whose salts are used as antiseptics.
Approved
Matched Synonyms: … N,N,N-Trimethyl-1-hexadecanaminium …
Matched Mixtures name: … CLORHEXIDINA AL 4% Y CETRIMIDA AL 1% JABÓN ANTISÉPTICO …
Matched Products: … XORTRIM 1 Cetrimide 1% w/v lotion ... Cetrimide Aqueous Soln 1% ... Resdan Dandruff Treatment Liquid 1% …
Matched Mixtures name: … CLORHEXIDINA AL 4% Y CETRIMIDA AL 1% JABÓN ANTISÉPTICO …
Matched Products: … XORTRIM 1 Cetrimide 1% w/v lotion ... Cetrimide Aqueous Soln 1% ... Resdan Dandruff Treatment Liquid 1% …
Inosine pranobex
Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug.
Approved
Matched Synonyms: … Inosine-2-hydroxypropyldimethylammonium 4-acetamidobenzoate (1:3) …
Matched Iupac: … tris((2R)-1-(dimethylamino)propan-2-ol); tris(4-acetamidobenzoic acid); 9-[(2R,3R,4S,5R)-3,4-dihydroxy …
Matched Iupac: … tris((2R)-1-(dimethylamino)propan-2-ol); tris(4-acetamidobenzoic acid); 9-[(2R,3R,4S,5R)-3,4-dihydroxy …
Displaying drugs 126 - 150 of 10565 in total