Showing BioInteractions for Plazomicin (DB12615)
BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Plazomicin is a 30S ribosomal protein S14 inhibitor | ||
| 1 | 30S ribosomal protein S14 inhibitors | Chlortetracycline, Omadacycline, Tetracycline |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Plazomicin is a 30S ribosomal protein S11 inhibitor | ||
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Plazomicin is a Multidrug and toxin extrusion protein 1 inhibitor | ||
| 1 | Multidrug and toxin extrusion protein 1 substrates | Acyclovir, Cefradine, Cephalexin, Cimetidine, Ciprofloxacin, Emtricitabine, Estrone sulfate, Flecainide, Ganciclovir, Guanidine, Levofloxacin, Metformin, N-methylnicotinamide, Nadolol, Procainamide, Relebactam, Tetraethylammonium, Tipiracil, Topotecan, Trimethoprim |
| 2 | Multidrug and toxin extrusion protein 1 inhibitors | Abemaciclib, Apalutamide, Bictegravir, Brigatinib, Capmatinib, Cimetidine, Ciprofloxacin, Famotidine, Fedratinib, Flecainide, Gilteritinib, Glasdegib, Guanfacine, Istradefylline, Lasmiditan, Levofloxacin, Lofexidine, Methylene blue, Osilodrostat, Pemigatinib, Pexidartinib, Pralsetinib, Pyrimethamine, Ranolazine, Remdesivir, Rifamycin, Rimegepant, Ripretinib, Risdiplam, Rucaparib, Selpercatinib, Tafenoquine, Tazemetostat, Tirbanibulin, Topotecan, Trimethoprim, Tucatinib, Verapamil |
| Interacting Group | Interacting Drugs | |
|---|---|---|
| Plazomicin is a Multidrug and toxin extrusion protein 2 inhibitor | ||
| 1 | Multidrug and toxin extrusion protein 2 substrates | Acyclovir, Baricitinib, Cimetidine, Estrone sulfate, Ganciclovir, Metformin, N-methylnicotinamide, Nadolol, Procainamide, Relebactam, Topotecan, Trastuzumab deruxtecan, Trimethoprim |
| 2 | Multidrug and toxin extrusion protein 2 inhibitors | Abemaciclib, Apalutamide, Baricitinib, Brigatinib, Capmatinib, Cimetidine, Ciprofloxacin, Copanlisib, Fedratinib, Glasdegib, Istradefylline, Lasmiditan, Levofloxacin, Methylene blue, Pexidartinib, Pralsetinib, Pyrimethamine, Ranolazine, Risdiplam, Rucaparib, Tafenoquine, Tazemetostat, Tirbanibulin, Trimethoprim, Tucatinib, Verapamil |