Left Ventricular Hypertrophy

Also known as: Hypertrophy, Left Ventricular / Left ventricular hypertrophy / Ventricular Hypertrophies, Left / Ventricular hypertrophy / Left ventricular enlargement / LVH

DrugDrug NameDrug Description
DB00999HydrochlorothiazideA thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It has been used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
DB00678LosartanLosartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. Losartan and its longer acting metabolite, E-3174, lower blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); they compete with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents the blood pressure increasing effects of angiotensin II. Unlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough. Losartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and diabetic nephropathy. It may also be used as an alternative agent for the treatment of systolic dysfunction, myocardial infarction, coronary artery disease, and heart failure.
DrugDrug NamePhaseStatusCount
DB08893Mirabegron2Enrolling by Invitation1
DB01074Perhexiline2 / 3Unknown Status1
DB00177Valsartan2 / 3Not Yet Recruiting1
DB09026Aliskiren3Completed1
DB00335Atenolol3Completed1
DB00335Atenolol3Terminated1
DB00796Candesartan cilexetil3Unknown Status1
DB00016Erythropoietin3Completed1
DB00722Lisinopril3Completed1
DB00722Lisinopril3Terminated1
DB00678Losartan3Completed1
DB00910Paricalcitol3Completed1
DB00910Paricalcitol3Terminated1
DB00437Allopurinol4Completed3
DB00381Amlodipine4Completed1
DB00381Amlodipine4Recruiting1
DB00542Benazepril4Completed1
DB00796Candesartan cilexetil4Completed1
DB00310Chlorthalidone4Recruiting1
DB06292Dapagliflozin4Active Not Recruiting1
DB01590Everolimus4Recruiting2
DB01023Felodipine4Completed1
DB00922Levosimendan4Terminated1
DB00678Losartan4Recruiting1
DB00688Mycophenolate mofetil4Recruiting1
DB04861Nebivolol4Completed1
DB00082Pegvisomant4Unknown Status1
DB00864Tacrolimus4Recruiting1
DB00820Tadalafil4Recruiting1
DB00177Valsartan4Completed2
DB00678LosartanNot AvailableCompleted2