Analgesics, Opioids

Also known as: Analgesics，Opioid / Analgesic, Opioid / Analgesics Opioid / Analgesics, Opioid / Opioid Analgesics / Opioid Analgesic

Drug	Drug Name	Drug Description
DB00316	Acetaminophen	An analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.

Drug	Drug Name	Target	Type
DB00316	Acetaminophen	Prostaglandin G/H synthase 1	target
DB00316	Acetaminophen	Prostaglandin G/H synthase 2	target
DB00316	Acetaminophen	Cytochrome P450 1A2	enzyme
DB00316	Acetaminophen	Cytochrome P450 2E1	enzyme
DB00316	Acetaminophen	P-glycoprotein 1	transporter
DB00316	Acetaminophen	Cytochrome P450 2D6	enzyme
DB00316	Acetaminophen	Cytochrome P450 2A6	enzyme
DB00316	Acetaminophen	Cytochrome P450 3A4	enzyme
DB00316	Acetaminophen	UDP-glucuronosyltransferase 1-1	enzyme
DB00316	Acetaminophen	UDP-glucuronosyltransferase 1-6	enzyme
DB00316	Acetaminophen	UDP-glucuronosyltransferase 1-9	enzyme
DB00316	Acetaminophen	UDP-glucuronosyltransferase 2B15	enzyme
DB00316	Acetaminophen	Sulfotransferase 1A1	enzyme
DB00316	Acetaminophen	Sulfotransferase 1A3/1A4	enzyme
DB00316	Acetaminophen	Arylamine N-acetyltransferase 2	enzyme
DB00316	Acetaminophen	Prostaglandin E synthase 3	target
DB00316	Acetaminophen	Transient receptor potential cation channel subfamily V member 1	target
DB00316	Acetaminophen	Serum albumin	carrier
DB00316	Acetaminophen	Fatty-acid amide hydrolase 1	enzyme
DB00316	Acetaminophen	Glutathione S-transferase P	enzyme
DB00316	Acetaminophen	Glutathione S-transferase Mu 1	enzyme

Drug	Drug Name	Phase	Status	Count
DB00327	Hydromorphone	1	Completed	1
DB00921	Buprenorphine	1 / 2	Completed	1
DB11951	Lemborexant	1 / 2	Completed	1
DB01183	Naloxone	1 / 2	Completed	1
DB00813	Fentanyl	2	Completed	1
DB00899	Remifentanil	2	Completed	1
DB00921	Buprenorphine	2 / 3	Completed	1
DB00193	Tramadol	2 / 3	Completed	1
DB00316	Acetaminophen	3	Completed	1
DB00316	Acetaminophen	3	Recruiting	1
DB01234	Dexamethasone	3	Completed	1
DB01234	Dexamethasone	3	Recruiting	1
DB00633	Dexmedetomidine	3	Completed	2
DB00633	Dexmedetomidine	3	Recruiting	1
DB00813	Fentanyl	3	Completed	1
DB00996	Gabapentin	3	Completed	1
DB00996	Gabapentin	3	Recruiting	1
DB00327	Hydromorphone	3	Completed	4
DB01221	Ketamine	3	Completed	1
DB01221	Ketamine	3	Recruiting	1
DB00281	Lidocaine	3	Completed	1
DB00281	Lidocaine	3	Recruiting	1
DB00653	Magnesium sulfate	3	Recruiting	1
DB05354	Morphine	3	Completed	1
DB00904	Ondansetron	3	Completed	1
DB00904	Ondansetron	3	Recruiting	1
DB01236	Sevoflurane	3	Completed	1
DB01236	Sevoflurane	3	Recruiting	1
DB00708	Sufentanil	3	Recruiting	1
DB00297	Bupivacaine	4	Completed	1
DB00297	Bupivacaine	4	Withdrawn	1
DB01161	Chloroprocaine	4	Completed	1
DB01234	Dexamethasone	4	Withdrawn	1
DB00668	Epinephrine	4	Completed	1
DB00327	Hydromorphone	4	Completed	1
DB00281	Lidocaine	4	Completed	1
DB00333	Methadone	4	Completed	1
DB00295	Morphine	4	Completed	2
DB00633	Dexmedetomidine	Not Available	Completed	1
DB00813	Fentanyl	Not Available	Completed	1
DB00899	Remifentanil	Not Available	Completed	1
DB00296	Ropivacaine	Not Available	Withdrawn	1