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Displaying drugs 126 - 150 of 13643 in total

Alprostadil

Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for whom oral treatment...
Approved
Investigational
Matched Description: … or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for ... depend on a patent ductus for survival until corrective or palliative surgery can be performed. ... Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator …
Matched Categories: … Drugs Used in Erectile Dysfunction …
Matched Products: … CAVERJECT POWDER FOR INJECTION 10 mcg/ml ... CAVERJECT POWDER FOR INJECTION 20 mcg/ml ... Muse 125 Mikrogramm - Stäbchen zur Anwendung in der Harnröhre …

Levofloxacin

Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic ofloxacin. It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin and remains stereochemically stable following administration (i.e. it does not invert to the inactive isomer). Levofloxacin, along with other quinolones...
Approved
Investigational
Matched Description: … [A31453,A190756] Levofloxacin was first approved by the FDA in 1996, and was approved in Canada and ... Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin]. ... [L11638] Levofloxacin, along with other quinolones such as [gatifloxacin] and [moxifloxacin], is a member …
Matched Categories: … Medications that reduce magnesium levels ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Levofloxacin In 5% Dextrose Injection ... For Infusion 5mg/ml ... Levores 5mg/ml Solution for Infusion …

Asparaginase Escherichia coli

Asparaginase derived from Escherichia coli (L-asparagine amidohydrolase, EC 3.5.1.1) is an enzyme responsible for the metabolism of L-asparagine, by catalyzing L-asparagine into L-aspartic acid and ammonia. It also facilitates the production of oxaloacetate which is needed for general cellular metabolism. Asparaginase from E. coli has clinically shown to exhibit antitumor...
Approved
Investigational
Matched Description: … treatment of acute lymphoblastic leukemia (ALL) as part of a multi-agent chemotherapeutic regimen. ... Therapeutic L-asparaginase from _E. coli_ works by depleting the levels of non-essential amino acid, ... asparagine, in lymphoblastic leukemic cells thus promoting apoptotic cell death [A31999]. …
Matched Products: … LEUNASE FOR INJECTION 10,000 iu/vial …

Iron

A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron...
Approved
Matched International brands: … Ed-In-Sol ... Fer-In-Sol …
Matched Description: … A metallic element found in certain minerals, in nearly all soils, and in mineral waters. ... Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms ... Iron is used to build up the blood in anemia. …
Matched Mixtures name: … For-2 ... ONE A DAY TABLET ... Complete One A Day Tab …
Matched Products: … FER-IN-SOL ... VENOFER SOLUTION FOR INJECTION 100 mg/5 ml ... COMPLEJO DE HIDROXIDO DE HIERRO EN SACAROSA EQUIVALENTE A 100 MG DE HIERRO ELEMENTAL INYECTABLE …

Vidarabine

A nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the vaccinia VIRUS and varicella zoster virus.
Approved
Investigational
Matched International brands: … Arasena-A …
Matched Description: … It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures ... A nucleoside antibiotic isolated from Streptomyces antibioticus. ... and significant antiviral activity against infections caused by a variety of viruses such as the herpes …
Matched Categories: … Antivirals for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Vira-A …

Diphenhydramine

Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched Description: … Diphenhydramine has also been shown to be implicated in a number of neurotransmitter systems that affect ... As a result, diphenhydramine is being investigated for its anxiolytic and anti-depressant properties. ... Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation …
Matched Mixtures name: … Benylin for Children All-IN-one Cold & Fever Nightime ... Mucus Relief All in One Maximum Strength ... Benylin All-IN-one Cold and Flu Night PE Caplets …
Matched Categories: … Antihistamines for Topical Use ... Antihistamines for Systemic Use …
Matched Products: … A Health Itch Relief Gel ... Only For SLEEP ... Only For ALLERGY …

Cephalexin

Cephalexin is the first of the first generation cephalosporins.[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,Label] Cephalexin was approved by the FDA on 4 January 1971.
Approved
Investigational
Vet approved
Matched Description: … [A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. ... [A179071] Cephalexin is used to treat a number of susceptible bacterial infections through inhibition …
Matched Categories: … Medications that reduce magnesium levels ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … SOFILEX FOR ORAL SUSPENSION 125 mg/5 ml ... OSPEXIN FOR ORAL SUSPENSION 250 mg/5 ml ... FELEXIN 250 FOR ORAL SUSPENSION 250 mg/5 ml …

Methotrexate

Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Description: … Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis ... effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in ... [A180322,L7144,L7147,L7150,L7180] Due to the toxic effects of methotrexate, it is indicated for treatment …
Matched Categories: … OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … TREXOL - Methotrexate Solution for Injection 25 mg/ml ... METOTREXATO 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... TREXOL - Methotrexate Solution for Injection 100 mg/ml …

Cisplatin

Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas and germ cell tumors. It was the first member of its class, which now also includes carboplatin and oxaliplatin.
Approved
Matched Description: … Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Medications that reduce magnesium levels ... OCT2 Substrates with a Narrow Therapeutic Index ... Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Matched Products: … CISPLATIN CS 50MG IN 50ML INJ ... CISPLATIN CONCENTRATE FOR SOLUTION FOR INFUSION 1 mg/ml ... CISPLATINO 10 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …

Cupric sulfate

Cupric sulfate is a salt created by treating cupric oxide with sulfuric acid. This forms as large, bright blue crystals containing five molecules of water (CuSO4∙5H2O) and is also known as blue vitriol. The anhydrous salt is created by heating the hydrate to 150 °C (300 °F). Cupric sulfate is...
Approved
Matched Description: … in analytic chemistry, as an electrolyte for batteries and electroplating baths, and in medical practice ... Some of its secondary uses are as a raw material in the preparation of other copper compounds, as a reagent ... Cupric sulfate is used primarily for agricultural purposes, as a pesticide, germicide, feed additive, …
Matched Mixtures name: … One-A-day Advance Men's ... One A Day Advance Adults ... One A Day Advance Adults 50+ …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Ibuprofen

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and...
Approved
Matched Description: … 1960 while researching for a safer alternative for aspirin. ... in the UK in 1969 and USA in 1974. ... [A39076] On the available products, ibuprofen is administered as a racemic mixture. …
Matched Mixtures name: … Doc in the Box All Day Supply ... Ibuprofen Cold and Sinus A P J ... CVS All Purpose First Aid Kit …
Matched Categories: … Topical Products for Joint and Muscular Pain ... Experimental Unapproved Treatments for COVID-19 ... Antiinflammatory Products for Vaginal Administration ... Antiinflammatory Preparations, Non-Steroids for Topical Use …
Matched Products: … NUROFEN FOR CHILDREN ... NUROFEN FOR CHILDREN 200MG/5ML ... Ibuprofen Fast relief medicine for pain …

Docetaxel

Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Description: … [L46466] Docetaxel was approved by the FDA in 1996 and is available in solution for injection for intravenous ... Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment ... [A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …
Matched Products: … DOCETAXEL DONG-A ... Taxotere 20mg/1ml concentrate for solution for infusion ... Daxotel Concentrate for Solution for Infusion 20mg/ml …

Somatotropin

Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood...
Approved
Investigational
Matched Description: … [A228183, L31508] Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone ... [A228188] Recombinant growth hormone is available as a subcutaneous injection for children and adults ... [A228183] Growth hormone therapy is approved for various disorders of growth hormone deficiency, …
Matched Products: … SciTropin A Solution for Injection 5 mg/1.5 ml ... SciTropin A Solution for Injection 10 mg/1.5 ml ... SciTropin A 10mg/1.5ml (30 IU) Cartridge Solution for Injection …

Amphetamine

Amphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs. It was previously used for a large variety of conditions and this changed until this point where its use is highly restricted. Amphetamine, with the chemical formula alpha-methylphenethylamine, was discovered in 1910 and first...
Approved
Illicit
Investigational
Matched Description: … It was previously used for a large variety of conditions and this changed until this point where its ... This use derived into a large overproduction of amphetamine and all the surplus after the war finalized ... Amphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs …
Matched Mixtures name: … Mixed Salts of a Single-Entity Amphetamine Product ... Mixed Salts of a Single-Entity Amphetamine Product ... Mixed Salts of a Single-Entity Amphetamine Product …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …

Phenol

Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. Phenol is also used as an oral analgesic or anesthetic in products...
Approved
Experimental
Matched Description: … Additionally, phenol and its related compounds are used in surgical ingrown toenail treatment, a process ... Phenol is also used as an oral analgesic or anesthetic in products such as Chloraseptic to treat pharyngitis ... It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly …
Matched Mixtures name: … Kank-A with Blistex Medicated Lip ... Sterile Diluent for Allergenic Extract ... Sterile Diluent for Allergenic Extract …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Sclerosing Agents for Local Injection …
Matched Products: … Pain A Lay ... Sterile Diluent for Allergenic Extract …

Cyanocobalamin

Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria , and is necessary for DNA synthesis and cellular energy production. Vitamin B12 has many forms, including the cyano-,...
Approved
Nutraceutical
Matched Description: … Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name ... This vitamin is produced naturally by bacteria [A175276], and is necessary for DNA synthesis and cellular ... This drug was initially approved by the FDA in 1942 [FDA label]. …
Matched Mixtures name: … Toni Com Liq ... Insur-all Vitamin Supplement ... Harvest Of Values All B Complex Tab …

Abacavir

Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring. In vivo, abacavir sulfate dissociates to its free base, abacavir.
Approved
Investigational
Matched Description: … In vivo, abacavir sulfate dissociates to its free base, abacavir. ... Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV ... Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration …
Matched Mixtures name: … N/A …
Matched Categories: … Antivirals used in combination for the treatment of HIV infections ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use …

alpha-Linolenic acid

Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition.
Approved
Investigational
Nutraceutical
Matched Synonyms: … all-cis-9,12,15-Octadecatrienoic acid …
Matched Description: … Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. ... It is a component of many common vegetable oils and is important to human nutrition. …

Pseudoephedrine

Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Description: … [A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional ... Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic ... Eastern medicine and were first researched in the west in 1889. …
Matched Mixtures name: … Benylin for Children All-IN-one Cold & Fever ... Benylin for Children All-IN-one Cold and Fever ... Viva Cold & Flu All In One Relief Caplets …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Nasal Decongestants for Systemic Use …
Matched Products: … Benylin D for Infants …

Paliperidone

Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin...
Approved
Matched Iupac: … [4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-4H,6H,7H,8H,9H-pyrido[1,2-a] …
Matched Description: … It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination ... Paliperidone was approved by the FDA for treatment of schizophrenia on December 20, 2006. ... intramuscular injection, and a twice-yearly gluteal injection. …
Matched Products: … Palibon 25 mg Depot-Injektionssuspension in einer Fertigspritze ... Palibon 50 mg Depot-Injektionssuspension in einer Fertigspritze ... Palibon 75 mg Depot-Injektionssuspension in einer Fertigspritze …

Vitamin E

In 1922, vitamin E was demonstrated to be an essential nutrient . Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol being the most biologically active . Vitamin E acts as an antioxidant, protecting cell membranes from oxidative damage . The antioxidant effects...
Approved
Nutraceutical
Vet approved
Matched Description: … The antioxidant effects are currently being researched for use in the treatment of diseases causing bone ... In 1922, vitamin E was demonstrated to be an essential nutrient[A32448]. ... Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol …
Matched Mixtures name: … For-2 ... Aces Formula/formule A A S ... ONE A DAY TABLET …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Arformoterol

Arformoterol is a bronchodilator. It works by relaxing muscles in the airways to improve breathing. Arformoterol inhalation is used to prevent bronchoconstriction in people with chronic obstructive pulmonary disease, including chronic bronchitis and emphysema. The use of arformoterol is pending revision due to safety concerns in regards to an increased...
Approved
Investigational
Matched Description: … Arformoterol is a bronchodilator. It works by relaxing muscles in the airways to improve breathing. ... using long-acting beta agonists for the treatment of asthma. ... The use of arformoterol is pending revision due to safety concerns in regards to an increased risk of …

Polymyxin B

Polymyxin B was discovered in the 1940s . They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes . Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label]. All gram-positive bacteria, fungi, and the gram-negative cocci,...
Approved
Vet approved
Matched Description: … Polymyxin B was discovered in the 1940s[A176429]. ... All gram-positive bacteria, fungi, and the gram-negative cocci, are resistant[A176426]. ... Polymyxin B has a narrow therapeutic index and so its use is limited and unlikely to be used first line …
Matched Mixtures name: … Water-Jel 3-in-1 Antibiotic ... Zee 3-in-One First Aid Antibiotic ... CVS Health All Purpose Kit …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Polymyxin B for Injection USP ... POLY-MxB for Injection U.S.P. 500,000 Units (Lyophilized) …

Tobramycin

Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Description: … in a variety of forms for administration by inhalation, injection, and external application to the eye ... [A232294] Inhaled tobramycin is notable for its use in treating chronic _Pseudomonas aeruginosa_ infections ... and ototoxicity, yet it remains a valuable option in the face of growing resistance to front-line antibiotics …
Matched Categories: … Medications that reduce magnesium levels ... Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Tobramycin in Sodium Chloride ... Tobramycin for Injection ... Tobramycin for Injection USP …

Anidulafungin

Anidulafungin or Eraxis is an anti-fungal drug manufactured by Pfizer that gained approval by the Food and Drug Administration (FDA) in February 21, 2006; it was previously known as LY303366. There is preliminary evidence that it has a similar safety profile to caspofungin.
Approved
Investigational
Matched Description: … There is preliminary evidence that it has a similar safety profile to caspofungin. ... anti-fungal drug manufactured by Pfizer that gained approval by the Food and Drug Administration (FDA) in …
Matched Categories: … Antimycotics for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … GIXOFU 100 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... ANIDACCORD 100 POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100 MG ... ERAXIS 100MG FOR INJECTION …
Displaying drugs 126 - 150 of 13643 in total