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Displaying drugs 76 - 100 of 15063 in total
A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Approved
Matched Synonyms: … 2-[p-chloro-α-[2-(dimethylamino)ethyl]benzyl]pyridine
Matched Description: … A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. ... One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and
Matched Mixtures name: … Acetaminophen, Ascorbic acid, Chlorpheniramine Maleate ... Phenylephrine Hydrochloride, Chlorpheniramine Maleate ... Hydrocodone Bitartrate Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride
Matched Salts name: … Chlorpheniramine hydrochloride
Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. It is a short-to-intermediate acting member of barbiturates that exhibit muscle-relaxing and anti-anxiety properties that produce central nervous system (CNS) depression that ranges from...
Approved
Illicit
Matched Synonyms: … Allylbarbituric acid ... iso-butylallylbarbituric acid ... 5-allyl-5-isobutylbarbituric acid
Matched Description: … Butalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens ... headaches, butalbital is often combined with one or more therapeutic agents, such as acetylsalicylic acid ... , acetaminophen, aspirin, and caffeine. …
Matched Mixtures name: … Butalbital, Aspirin, and Caffeine ... Butalbital, Aspirin and Caffeine ... Butalbital, Aspirin, and Caffeine …
Matched Categories: … Hypnotics and Sedatives …
Approved
Nutraceutical
Matched Synonyms: … Ascorbic acid, magnesium salt ... L(+)-ascorbic acid magnesium salt …
Matched Categories: … Diet, Food, and Nutrition …
Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.
Approved
Investigational
Matched Synonyms: … 2-mercaptoethanesulfonic acid ... 2-mercaptoethanesulphonic acid ... β-mercaptoethanesulfonic acid
Matched Iupac: … 2-sulfanylethane-1-sulfonic acid
Matched Description: … used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis. ... Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is …
Matched Mixtures name: … IFEX and MESNEX ... IFEX and MESNEX ... IFEX and MESNEX …
Matched Categories: … Cough and Cold Preparations …
Bumetanide is a sulfamyl diuretic.
Approved
Matched Synonyms: … 3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid
Matched Iupac: … 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid
Matched Categories: … bumetanide and potassium ... Genito Urinary System and Sex Hormones ... bumetanide and potassium-sparing agents ... Gynecological Antiinfectives and Antiseptics ... High-Ceiling Diuretics and Potassium-Sparing Agents …
Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power...
Approved
Matched Description: … It is also a toxic air pollutant produced by automobile engines and power plants. ... This gas is an important signaling molecule in the body of mammals including humans and is an extremely …
Matched Categories: … Nitrates and Nitrites …
Matched Products: … roots extract Mesoporous Silica Nanoparticle Zinc) Nitric Oxide, Dexpanthenol, Niacinamide, Salicylic acid ... roots extract Mesoporous Silica Nanoparticle, Zinc) Nitric Oxide, Dexpanthenol, Niacinamide, Salicylic acid ... IBSIBD NO 180 Start (Helps improve intestinal healthy and immunity, Lettuce and Soybean fermented powder …
Vigabatrin is an analog of gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and infantile spasms. It irreversibly inhibits the enzyme responsible for GABA metabolism, thereby increasing levels of circulating GABA. Although administered as a racemic mixture, only the...
Approved
Matched Synonyms: … 4-Amino-5-hexenoic acid ... Vinyl gamma-aminobutyric acid ... gamma-Vinyl-gamma-aminobutyric acid
Matched Iupac: … 4-aminohex-5-enoic acid
Matched Description: … Vigabatrin is an analog of gamma-aminobutyric acid ([GABA]), the main inhibitory neurotransmitter in ... the central nervous system, used in the treatment of refractory seizures and infantile spasms. ... [A202037] It was first introduced as an antiepileptic agent in the United Kingdom in 1989 and was …
Matched Categories: … Fatty Acid Derivatives …
Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Approved
Investigational
Vet approved
Matched Synonyms: … Etodolic acid ... (±)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid ... 1,3,4,9-tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid
Matched Iupac: … 2-{1,8-diethyl-1H,3H,4H,9H-pyrano[3,4-b]indol-1-yl}acetic acid
Matched Description: … It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis. ... Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Approved
Investigational
Matched Synonyms: … Phenobarbituric Acid ... Phenylethylbarbituric Acid ... 5-Ethyl-5-phenylbarbituric acid
Matched Description: … It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents ... A barbituric acid derivative that acts as a nonselective central nervous system depressant. …
Matched Mixtures name: … Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Categories: … Excitatory Amino Acid Agents ... Excitatory Amino Acid Antagonists ... Barbiturates and Derivatives ... Hypnotics and Sedatives ... Phenobarbital and similars …
An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit...
Approved
Nutraceutical
Withdrawn
Matched Synonyms: … (S)-α-amino-1H-indole-3-propanoic acid ... (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid ... (S)-alpha-Amino-beta-(3-indolyl)-propionic acid
Matched Iupac: … (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid
Matched Description: … An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults ... It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Travasol Amino Acid Inj 8.5% …
Matched Categories: … Amino Acids, Peptides, and Proteins …
One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action.
Approved
Matched Description: … It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. ... Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating …
Matched Mixtures name: … Dopamine Hydrochloride and 5% Dextrose Injection USP ... Dopamine Hydrochloride and 5% Dextrose Injection USP ... Dopamine Hydrochloride and 5% Dextrose Injection USP …
Matched Salts name: … Dopamine hydrochloride
Matched Categories: … Adrenergic and Dopaminergic Agents …
Matched Products: … DOPamine Hydrochloride and Dextrose ... Dopamine Hydrochloride and Dextrose ... DOPamine HYDROCHLORIDE AND DEXTROSE …
Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.
Approved
Matched Synonyms: … Dipotassium acid phosphate ... Phosphoric acid, dipotassium salt ... Phosphoric acid, potassium salt (1:2) …
Matched Description: … as a source of phosphorus and potassium as well as a buffering agent. ... Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive …
Matched Mixtures name: … Ionosol B and Dextrose ... Travasol Amino Acid Inj 8.5% ... Travasol Amino Acid Inj 5.5% …
A fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)
Approved
Investigational
Matched Synonyms: … 2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester ... alpha-(p-Chlorophenoxy)isobutyric acid, ethyl ester ... 2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl ester …
Matched Description: … A fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia …
Matched Categories: … Clofibric Acid
The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets from the market on August 5, 1982.
Approved
Withdrawn
Matched Synonyms: … (1)-2-(4-Chlorophenyl)benzoxazole-5-propionic acid ... 2-(4-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid ... 2-(p-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid
Matched Iupac: … 2-[2-(4-chlorophenyl)-1,3-benzoxazol-5-yl]propanoic acid
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Ceftobiprole medocaril is a prodrug of ceftobiprole, a fifth-generation semisynthetic cephalosporin antibacterial. Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative bacteria, including antibiotic-resistant strains of Staphylcoccus aureus (methicillin-resistant Staphylococcus aureus; MRSA). The EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a negative opinion...
Approved
Experimental
Investigational
Matched Synonyms: … Ceftobiprole medocaril free acid
Matched Iupac: … -2-oxo-[1,3'-bipyrrolidin]-3-ylidene]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Matched Description: … infections and bacteremia in April 2024. ... Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative ... was subsequently approved in the United States with additional indications for skin and skin structure …
Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.
Approved
Matched Synonyms: … 4-aminobenzene sulfonic acid amide …
Matched Categories: … Sulfonamides and trimethoprim ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Synonyms: … 4-aminobenzoic acid 2-diethylaminoethyl ester ... p-Aminobenzoic acid 2-diethylaminoethyl ester …
Matched Description: … A local anesthetic of the ester type that has a slow onset and a short duration of action. ... It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. …
Matched Salts name: … Procaine hydrochloride
Matched Categories: … Esters of Aminobenzoic Acid ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Procaine Hydrochloride
An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Approved
Withdrawn
Matched Synonyms: … p-2-thenoylhydratropic acid ... (±)-2-(p-(2-thenoyl)phenyl)propionic acid ... 2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid
Matched Iupac: … 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid
Matched Description: … An ibuprofen-type anti-inflammatory analgesic and antipyretic. ... It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Icosapent ethyl or ethyl eicosapentaenoic acid is a synthetic derivative of the omega-3 fatty acid eicosapentaenoic acid (EPA). It is used as an adjunct therapy for severe hypertriglyceridemia (TG levels > 500 mg/dL) and to reduce the risk of cardiovascular events in certain patients with elevated triglycerides. FDA approved on...
Approved
Investigational
Nutraceutical
Matched Synonyms: … ethyl-eicosapentaenoic acid ... Timnodonic acid ethyl ester ... Eicosapentaenoic acid ethyl ester …
Matched Description: … acid (EPA). ... It is used as an adjunct therapy for severe hypertriglyceridemia (TG levels > 500 mg/dL) and to reduce ... Icosapent ethyl or ethyl eicosapentaenoic acid is a synthetic derivative of the omega-3 fatty acid eicosapentaenoic …
Glucarpidase is a recombinant carboxypeptidase G2 produced by genetically modified Escherichia coli bacteria. It is a 390-amino acid homodimer protein. High-dose methotrexate, an antifolate agent, has been widely and safely used for many decades in treating various cancers; however, even with aggressive hydration, urine alkalinization, and leucovorin rescue, some patients...
Approved
Investigational
Matched Synonyms: … Pteroylmonoglutamic acid hydrolase G2 …
Matched Description: … It is a 390-amino acid homodimer protein. ... [L39855] High-dose [methotrexate], an antifolate agent, has been widely and safely used for many decades ... This can lead to delayed renal clearance of methotrexate and elevated drug plasma levels, increasing …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Approved
Experimental
Matched Synonyms: … 4-hydroxybenzoic acid ethyl ester ... p-hydroxybenzoic acid ethyl ester …
A cephalorsporin antibiotic that is no longer commonly used.
Approved
Matched Synonyms: … Cephaoglycin acid ... 7-(2-D-alpha-Aminophenylacetamido)cephalosporanic acid ... 7-(D-alpha-Aminophenyl-acetamido)cephalosporanic acid
Matched Iupac: … acetyloxy)methyl]-7-[(2R)-2-amino-2-phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Synonyms: … 2-amino-3-(4-bromobenzoyl)benzeneacetic acid ... [2-Amino-3-(4-bromo-benzoyl)-phenyl]-acetic acid
Matched Iupac: … 2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record …
A lignan found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and...
Approved
Matched Synonyms: … Podophyllinic acid lactone …
Matched Description: … and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives. ... It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. ... It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts …
Matched Categories: … Skin and Mucous Membrane Agents …
Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Description: … drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and
Matched Mixtures name: … FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE ... FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE ... FEXOFENADINE HYDROCHLORIDE and PSEUDOEPHEDRINE HYDROCHLORIDE
Matched Salts name: … Pseudoephedrine hydrochloride
Matched Categories: … Alpha-and Beta-adrenergic Agonists …
Matched Products: … Pseudoephedrine Hydrochloride ... Pseudoephedrine hydrochloride ... Pseudoephedrine Hydrochloride Srt 120mg Tab …
Displaying drugs 76 - 100 of 15063 in total