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Displaying drugs 126 - 150 of 4759 in total
Asfotase alfa
Asfotase alfa is a first-in-class bone-targeted enzyme replacement therapy designed to address the underlying cause of hypophosphatasia (HPP)—deficient alkaline phosphatase (ALP). Hypophosphatasia is almost always fatal when severe skeletal disease is obvious at birth. By replacing deficient ALP, treatment with Asfotase Alfa aims to improve the elevated enzyme substrate levels...
Approved
Investigational
Matched Description: … Agency of Japan (PMDA) on July 3, 2015, then approved by the European Medicine Agency (EMA) on August 28 …
Matched Products: … STRENSİQ 28 MG/0.7 ML ENJEKSİYONLUK ÇÖZELTİ, 12 ADET …
Matched Products: … STRENSİQ 28 MG/0.7 ML ENJEKSİYONLUK ÇÖZELTİ, 12 ADET …
Ropinirole
Ropinirole, also known as ReQuip, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], . It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. In 2005, it was the first...
Approved
Investigational
Matched Products: … PARGUIP XL 2 MG UZATILMIŞ SALIMLI TABLET, 28 ADET ... PARGUIP XL 4 MG UZATILMIŞ SALIMLI TABLET, 28 ADET ... PARGUIP XL 8 MG UZATILMIŞ SALIMLI TABLET, 28 ADET …
Rofecoxib
Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras. Rofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 )...
Approved
Investigational
Withdrawn
Matched Products: … REOX 12.5 MG TABLET, 28 ADET ... REOX 25 MG FORT TABLET, 28 ADET …
Fludeoxyglucose (18F)
Fludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added radioactive 2-deoxy-2-[18F]fluoro-D-g1ucose, which is used for diagnostic purposes in conjunction with Positron Emission Tomography (PET). It is administered by intravenous injection.
Approved
Investigational
Matched Products: … STERIFDG 250 MBQ/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 6 DOZ …
Prasugrel
Prasugrel, a thienopyridine derivative, is a platelet activation and aggregation inhibitor structurally and pharmacologically related to clopidogrel and ticlopidine. Similar to clopidogrel, prasugrel is a prodrug that requires enzymatic transformation in the liver to its active metabolite, R-138727. R-138727 irreversibly binds to P2Y12 type ADP receptors on platelets thus preventing...
Approved
Matched Products: … EFFIENT 10 MG FILM KAPLI TABLET, 28 ADET ... SUGVİDA 10 MG FİLM KAPLI TABLET, 28 ADET …
Lisinopril
Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a...
Approved
Investigational
Matched Iupac: … (2S)-1-[(2S)-6-amino-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}hexanoyl]pyrrolidine-2-carboxylic acid …
Matched Mixtures name: … RILACE PLUS 20 MG/25 MG TABLET, 28 TABLET ... RILACE PLUS 20 MG/12.5 MG TABLET, 28 TABLET …
Matched Products: … APRIL-ACE 5 MG TABLET, 28 ADET ... APRIL-ACE 20 MG TABLET, 28 ADET ... RILACE 5 MG TABLET, 28 TABLET …
Matched Mixtures name: … RILACE PLUS 20 MG/25 MG TABLET, 28 TABLET ... RILACE PLUS 20 MG/12.5 MG TABLET, 28 TABLET …
Matched Products: … APRIL-ACE 5 MG TABLET, 28 ADET ... APRIL-ACE 20 MG TABLET, 28 ADET ... RILACE 5 MG TABLET, 28 TABLET …
Alpelisib
Alpelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potent antitumor activity. It works by selectively inhibiting class I PI3K p110α , which is the catalytic subunit of PI3K, a lipid kinase that plays a role in various biological processes, including proliferation, survival, differentiation, and metabolism. Alpelisib was designed to target...
Approved
Investigational
Matched Products: … PİMREVA 200 MG FİLM KAPLI TABLET, 28 ADET …
Racepinephrine
Racepinephrine is a racemic mixture consisting of d-DB00668 and l-DB00668 enantiomers. Epinephrine is a non-selective α- and β-adrenergic receptor agonist. It is a bronchodilator used in the temporary relief of mild symptoms of intermittent asthma including wheezing, tightness of chest and shortness of breath. It is an active ingredient in...
Approved
Matched Products: … Epidri 6% …
Etodolac
Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Approved
Investigational
Vet approved
Matched Products: … ETODIN FORT 400MG FILM TABLET, 28 ADET ... ETOL FORT 400 MG FILM TABLET, 28 ADET ... ETOTAC 400 MG FILM KAPLI TABLET, 28 ADET …
Eslicarbazepine acetate
Eslicarbazepine acetate (ESL) is an anticonvulsant medication approved for use in Europe, the United States and Canada as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy. Eslicarbazepine acetate is a prodrug that is rapidly converted to eslicarbazepine, the primary active metabolite in the body....
Approved
Matched Products: … ZEBINIX 400MG TABLET, TABLET, 28 ADET …
Lindane
An organochlorine insecticide that has been used as a pediculicide and a scabicide. Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment. In Canada, Lindane is not recommmended as a first-line therapy due to reports...
Approved
Withdrawn
Quinapril
Quinapril is the ethyl ester prodrug of the non-sulfhydryl angiotensin converting enzyme inhibitor quinaprilat.[L8420,L8423] It is used to treat hypertension and heart failure.[L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. Quinapril was granted FDA approval...
Approved
Investigational
Matched Description: … [L8420] A combination tablet with [hydrochlorothiazide] was also approved on 28 December 1999. …
Matched Products: … ACUITEL 40 MG FILM KAPLI TABLET, 28 ADET …
Matched Products: … ACUITEL 40 MG FILM KAPLI TABLET, 28 ADET …
Zolmitriptan
Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine.[A462, L12978] Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, and zolmitriptan. Triptans...
Approved
Investigational
Matched Products: … MIGTERA 5 MG FİLM TABLET, 6 ADET ... GRAVIS 5 MG FILM TABLET, 6 TABLET …
Eletriptan
Eletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches.
Approved
Investigational
Matched Salts cas: … 273211-28-2 …
Matched Products: … RELPAX 40 MG FILM TABLET, 6 ADET …
Matched Products: … RELPAX 40 MG FILM TABLET, 6 ADET …
Hydroquinone
Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids,...
Approved
Investigational
Matched Mixtures name: … Hydroquinone 6% /tretinoin 0.05% ... Hydrocortisone 0.5% / Hydroquinone 6% ... Hyaluronic Acid Sodium Salt 1% / Hydroquinone 6% …
Matched Products: … Hydroquinone 6% ... 141055 Hydroquinone 6% ... 141011 Hydroquinone 6% …
Matched Products: … Hydroquinone 6% ... 141055 Hydroquinone 6% ... 141011 Hydroquinone 6% …
Ethinylestradiol
Ethinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering. It was developed in an effort to create an estrogen with greater oral bioavailability. These properties were achieved by the substitution of an ethinyl group at carbon 17 of estradiol. Ethinylestradiol soon replaced mestranol in...
Approved
Matched Mixtures name: … Evra -(6/0.75) ... EVRA TRANSDERMAL PATCH (6 mg/600 mcg) ... Aviane 28 Day …
Agomelatine
Agomelatine is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. Agomelatine was developed in Europe by Servier Laboratories Ltd. and submitted to the European Medicines Agency (EMA) in 2005. The Committee...
Approved
Investigational
Matched Products: … VALDOXAN 25 MG FILM KAPLI TABLET, 28 ADET …
Insulin degludec
Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A18561,A18562,A18563,A18564,A174934] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Products: … TRESIBA FLEXTOUCH 200 U/ML ENJEKSIYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 6 ADET …
Risperidone
Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone). Schizophrenia and...
Approved
Investigational
Matched Iupac: … 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-4H,6H,7H,8H,9H-pyrido[1,2-a]pyrimidin …
Matched Salts cas: … 666179-92-6 …
Matched Products: … Risperdal 6 mg Filmtabletten ... WELRIS 6 MG FILM TABLET, 30 ADET ... WELRIS 6 MG FILM TABLET, 60 ADET …
Matched Salts cas: … 666179-92-6 …
Matched Products: … Risperdal 6 mg Filmtabletten ... WELRIS 6 MG FILM TABLET, 30 ADET ... WELRIS 6 MG FILM TABLET, 60 ADET …
Tocilizumab
Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies. Tocilizumab was granted FDA approval on 8 January 2010 to treat a...
Approved
Matched Description: … Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory ... was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 …
Matched Categories: … Interleukin-6 Receptor Antagonist …
Matched Categories: … Interleukin-6 Receptor Antagonist …
Glycopyrronium
Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergic medications.[A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the...
Approved
Investigational
Vet approved
Matched Mixtures name: … TRIMBOW PRESSURISED INHALATION SOLUTION 100/6/12.5 μg PER ACTUATION …
Matched Products: … PANTHERO NEOHALER 50 MIKROGRAM INHALER KAPSÜL, 6 ADET …
Matched Products: … PANTHERO NEOHALER 50 MIKROGRAM INHALER KAPSÜL, 6 ADET …
Pibrentasvir
Pibrentasvir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS5A inhibitor that targets the the viral RNA replication and viron assembly. In combination with DB13879, pibrentastiv is a useful therapy for patients who experienced therapeutic failure from other NS5A inhibitors. In cell cultures, the emergence of amino...
Approved
Investigational
Matched Iupac: … methyl N-[(2S,3R)-1-[(2S)-2-{5-[(2R,5R)-1-{3,5-difluoro-4-[4-(4-fluorophenyl)piperidin-1-yl]phenyl}-5-{6- ... methoxy-2-[(methoxycarbonyl)amino]butanoyl]pyrrolidin-2-yl]-1H-1,3-benzodiazol-5-yl}pyrrolidin-2-yl]-6- …
Matched Description: … for twelve or more weeks after the end of treatment, of ≥93% across genotypes 1a, 2a, 3a, 4, 5 and 6 ... therapy was FDA-approved in August 2017 to treat adults with chronic hepatitis C virus (HCV) genotypes 1-6 …
Matched Description: … for twelve or more weeks after the end of treatment, of ≥93% across genotypes 1a, 2a, 3a, 4, 5 and 6 ... therapy was FDA-approved in August 2017 to treat adults with chronic hepatitis C virus (HCV) genotypes 1-6 …
Fluvastatin
Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It...
Approved
Matched Iupac: … (6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid …
Matched Products: … LESCOL XL 80 MG TABLET, 28 ADET …
Matched Products: … LESCOL XL 80 MG TABLET, 28 ADET …
Fluorouracil
A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Approved
Besifloxacin
Besifloxacin is a fourth generation fluoroquinolone-type opthalmic antibiotic for the treatment of bacterial conjunctivitis. FDA approved on May 28, 2009.
Approved
Matched Iupac: … 7-[(3R)-3-aminoazepan-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … FDA approved on May 28, 2009. …
Matched Description: … FDA approved on May 28, 2009. …
Displaying drugs 126 - 150 of 4759 in total