Displaying drugs 301 - 325 of 407 in total
| Name | Weight | Structure | Desription | Categories |
|---|---|---|---|---|
| Siltuximab | 145000.0 C6450H9932N1688O2016S50 |  | An interleukin antagonist used to treat multicentric Castleman's disease (MCD) in patients who are HIV and HHV-8 negative. | Interleukin Inhibitors |
| Dinutuximab | 145000.0 C6422H9982N1722O2008S48 |  | An immunotherapeutic agent used in combination with other immunomodulating agents to treat high-risk neuroblastoma in pediatric patients who achieve at least a partial response to prior first-line multiagent, multimodality therapy. | Antibodies, Monoclonal |
| Atezolizumab | 145000.0 | | A monoclonal antibody used to treat advanced or metastatic urothelial carcinoma with disease progression during or up to 12 months after platinum-containing chemotherapy. | Antibodies, Monoclonal / PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors |
| Ocrelizumab | 145000.0 C6494H9978N1718O2014S46 | | A CD20 specific monoclonal antibody used to treat relapsing remitting multiple sclerosis. | Selective Immunosuppressants |
| Atoltivimab | 145097.54 C6448H9954N1726O2002S44 | | Part of a product containing three monoclonal IgG1κ antibodies directed against the GP1,2 glycoprotein of Zaire ebolavirus. Together, these three antibodies act to neutralize viral particles and to recruit immune effectors for the destruction of both viral particles and infected cells. | Antiviral Agents |
| Canakinumab | 145157.0 C6452H9958N1722O2010S42 |  | An interleukin-1β blocker used to treat Periodic Fever Syndromes such as Cryopyrin-Associated Periodic Syndromes (CAPS) and Familial Mediterranean Fever (FMF), and also to treat active Systemic Juvenile Idiopathic Arthritis (SJIA). | Interleukin Inhibitors |
| Daratumumab | 145391.67 C6466H9996N1724O2010S42 |  | A CD38-directed cytolytic antibody used alone or as an adjunct drug in the treatment of multiple myeloma and light chain amyloidosis. | Antibodies, Monoclonal / CD38 (Clusters of Differentiation 38) inhibitors |
| Alemtuzumab | 145453.8 C6468H10066N1732O2005S40 |  | A monoclonal anti-CD52 antibody used in the treatment of B-cell chronic lymphocytic leukemia and relapsing forms of multiple sclerosis. | Selective Immunosuppressants |
| Trastuzumab | 145531.5 C6470H10012N1726O2013S42 |  | A monoclonal anti-human epidermal growth factor receptor 2 protein antibody used to treat HER2-positive breast, gastroesophageal, and gastric cancers. | Antibodies, Monoclonal / HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors |
| Emicizumab | 145637.0 C6434-H9940-N1724-O2047-S45 |  | An antibody against Factor IXa and Factor X used to treat hemophilia A. | Amino Acids, Peptides, and Proteins / Antibodies / Antibodies, Monoclonal / Antibodies, Monoclonal, Humanized / Antihemorrhagic Agents, Miscellaneous / Blood and Blood Forming Organs / Blood Coagulation Factors / Blood Proteins / Globulins / Hemostatics / Immunoglobulins / Immunoproteins / Proteins / Serum Globulins |
| Abciximab | 145651.1 C6462H9964N1690O2049S48 |  | A monoclonal anti-glycoprotein IIb/IIIa receptor antibody used to prevent thrombosis during percutaneous coronary intervention. | Platelet Aggregation Inhibitors Excl. Heparin |
| Cetuximab | 145781.6 C6484H10042N1732O2023S36 |  | An endothelial growth factor receptor binding fragment used to treat colorectal cancer as well as squamous cell carcinoma of the head and neck. | Antibodies, Monoclonal / EGFR (Epidermal Growth Factor Receptor) inhibitors |
| Romosozumab | 145805.0 | | A monoclonal antibody used to treat osteoporosis in postmenopausal women at high risk of fracture, patients who are intolerant of other treatments, or patients who have failed other treatments. | Amino Acids, Peptides, and Proteins / Antibodies / Antibodies, Monoclonal / Antibodies, Monoclonal, Humanized / Blood Proteins / Bone Anabolic Agents / Drugs Affecting Bone Structure and Mineralization / Drugs for Treatment of Bone Diseases / Globulins / Immunoglobulins / Immunoproteins / Musculo-Skeletal System / Proteins / Sclerostin Inhibitors / Serum Globulins |
| Alirocumab | 146000.0 C6472H9996N1736O2032S42 |  | A PCSK9 inhibitor used as an adjunct to manage heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease in patients who require additional lowering of LDL-cholesterol (LDL-C). | Hypercholesterolemia, drug therapy / Hypolipidemic Agents Indicated for Hyperlipidemia / PCSK9 Inhibitor |
| Aducanumab | 146000.0 | | A monoclonal antibody indicated in the treatment of Alzheimer's disease. | Amyloid Beta-directed Antibodies |
| Lanadelumab | 146000.0 C6468H10016N1728O2012S47 |  | A monoclonal antibody targeted against kallikrein which is used to treat attacks of hereditary angioedema. | Drugs Used in Hereditary Angioedema |
| Cemiplimab | 146000.0 C6380H9808N1688O2000S44 | | A programmed death receptor-1 blocking antibody used to treat cutaneous squamous cell carcinoma, basal cell carcinoma, and non-small cell lung cancer. | PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors |
| Crizanlizumab | 146000.0 | | A monoclonal antibody that targets selectin to reduce the frequency of vasooclusive crises in patients with sickle cell disease. | Amino Acids, Peptides, and Proteins / Antibodies / Antibodies, Monoclonal / Antibodies, Monoclonal, Humanized / Blood and Blood Forming Organs / Blood Proteins / Globulins / Immunoglobulin G / Immunoglobulins / Immunoproteins / Proteins / Selectin Blocker / Serum Globulins |
| Spesolimab | 146000.0 C6480H9988N1736O2012S46 | | An interleukin-36 receptor antagonist used to treat generalized pustular psoriasis flares in adults. | Interleukin Inhibitors |
| Bamlanivimab | 146000.0 C6498H10068N1732O2032S46 | | A neutralizing human IgG1κ monoclonal antibody against the SARS-CoV-2 spike (S) protein for use in patients aged 12 and over at high risk of developing severe COVID-19. | Antiviral Agents |
| Evinacumab | 146000.0 | | A monoclonal antibody targeted against angiopoetin-like protein 3 (ANGPTL3) used as an adjunct with other lipid-lowering therapies for the treatment of homozygous familiar hypercholesterolemia. | Angiopoietin-like 3 Inhibitor |
| Teclistamab | 146000.0 C6383H9847N1695O2003S40 | | A bispecific B-cell maturation antigen (BCMA)-directed CD3 T cell engager used to treat relapsed and refractory multiple myeloma in adults as monotherapy. | Amino Acids, Peptides, and Proteins / Antibodies, Monoclonal / Bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager / Bispecific Monoclonal Antibodies / Blood Proteins / Immunoglobulins / Proteins / Serum Globulins |
| Benralizumab | 146054.0 C6492H10060N1724O2028S42 |  | A monoclonal antibody used to treat severe eosinophilic asthma. | Anti-Asthmatic Agents / Interleukin-5 Receptor alpha-directed Cytolytic Antibody |
| Ofatumumab | 146100.0 C6480H10022N1742O2020S44 |  | An anti-CD20 antibody used for the treatment of chronic lymphocytic leukemia (CLL) in selected patients with certain treatment histories and responsiveness to anticancer medications. | Antibodies, Monoclonal / CD20 (Clusters of Differentiation 20) inhibitors / Selective Immunosuppressants |
| Obinutuzumab | 146100.0 C6512H10060N1712O2020S44 |  | An antineoplastic CD20 antibody used to treat untreated chronic lymphocytic leukemia in combination with chlorambucil. | Antibodies, Monoclonal / CD20 (Clusters of Differentiation 20) inhibitors |
Displaying drugs 301 - 325 of 407 in total