Musculo-Skeletal System

Name
Musculo-Skeletal System
Accession Number
DBCAT002122
Description
Not Available
ATC Classification
Drugs
DrugDrug Description
MetocurineMetocurine is a muscle relaxant.
Botulinum Toxin Type BA purified form of botulinum toxin type B used to block acetylcholine release in the treatment of cervical dystonia and sialorrhea.
RasburicaseA recombinant form of urate-oxidase enzyme used to treat hyperuricemia following chemotherapy for leukemias and non-Hodgkin's lymphoma.
Botulinum toxin type AA purified form of botulinum toxin type A used to block acetylcholine release in the treatment of chronic sialorrhea, muscle spasticity, and dystonia, as well as in cosmetic applications.
CholecalciferolA form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease.
BaclofenA GABA-ergic agonist used to manage severe spasticity of cerebral or spinal origin in adult and pediatric patients.
SuccinylcholineA depolarizing skeletal muscle relaxant used as an adjunct to anesthesia and for skeletal muscle relaxation during intubation, mechanical ventilation, and surgical procedures.
Pamidronic acidA bisphosphonate used to treat Paget's disease, to treat hypercalcemia of malignancy, and to treat osteolytic bone lesions.
ChlorzoxazoneA drug with muscle relaxant properties that is used as an adjunct to physical therapy and analgesics to treat stiffness and pain caused by a variety of musculoskeletal conditions.
CarisoprodolA centrally acting muscle relaxant used to relieve the discomfort associated with various musculoskeletal conditions.
Zoledronic acidA bisphosphonate used to treat malignancy associated hypercalcemia, multiple myeloma, and bone metastasis from solid tumors.
MethocarbamolA CNS depressant indicated with rest, physical therapy and other treatments to control the discomfort associated with various acute musculoskeletal conditions.
AllopurinolA xanthine oxidase inhibitor used to reduce urinary and serum uric acid concentrations in patients with gout, recurrent calcium oxalate calculi, and various malignancies.
NabumetoneAn NSAID used to treat osteoarthritis and rheumatoid arthritis.
TenoxicamAn anti inflammatory analgesic used to treat mild to moderate pain as well as the signs and symptoms of rheumatoid arthritis and osteoarthritis.
TolmetinAn NSAID used to treat acute flares of various painful conditions and used for the long term management of osteoarthritis, rheumatoid arthritis, and juvenile arthritis.
RofecoxibA COX-2 inhibitor NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, primary dysmenorrhea, and migraine attacks.
PiroxicamAn NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis.
CisatracuriumA skeletal muscle relaxant used to facilitate tracheal intubation, muscle relaxation in surgery, or mechanical ventilation.
FenoprofenAn anti-inflammatory analgesic used to treat mild to moderate pain in addition to the signs and symptoms of rheumatoid arthritis and osteoarthritis.
ValdecoxibA COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea.
SulindacAn NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis.
Alendronic acidA bisphosphonate drug that prevents osteoclastic bone resorption and is used for the prevention and treatment of osteoporosis.
TizanidineAn alpha-2 adrenergic agonist used for the short-term treatment of muscle spasticity.
IbandronateA bisphosphonate used to treat osteoporosis in postmenopausal women.
Clodronic acidA bisphosphonate used to treat osteoporosis in postmenopausal women, hypercalcemia of malignancy, and osteolysis.
RocuroniumA vecuronium analog used to facilitate tracheal intubation and to relax skeletal muscles during surgery.
EtodolacAn NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain.
Mefenamic acidAn NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea.
PhenylbutazoneAn NSAID used to treat backache and ankylosing spondylitis.
MeloxicamAn NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics.
PenicillamineA chelator used to treat Wilson's disease, cystinuria, and rheumatoid arthritis.
SuprofenAn NSAID used to prevent pupil constriction in ocular surgery.
Risedronic acidA bisphosphonate used to treat osteoporosis and Paget's disease.
CyclobenzaprineA skeletal muscle relaxant that works on the brainstem to treat muscle spasms of local origin.
Meclofenamic acidAn NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis.
HexafluroniumUsed as an adjunct with succinylcholine (or suxamethonium chloride) to prolong muscle relaxation and to prevent succinylcholine-induced muscle fasciculations.
OxaprozinAn NSAID used to treat osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
AuranofinAn antirheumatic used to treat active, progressive, or destructive forms of inflammatory arthritis.
KetoprofenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain.
Etidronic acidA bisphosphonate drug that prevents osteoclastic bone resorption; used for the prevention and treatment of osteoporosis.
Dimethyl sulfoxideA reversible mitogen-activated extracellular signal-regulated kinase-1 (MEK1) and MEK2 inhibitor used to treat certain types of melanoma, metastatic non-small cell lung cancer, and locally advanced or metastatic anaplastic thyroid cancer.
Tiludronic acidA bisphosphonate used for the treatment of Paget's disease of bone.
DoxacuriumA nondepolarizing neuromuscular blocking agent used as an adjunct to general anesthesia to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgical procedures.
SulfinpyrazoneA platelet inhibitory and uricosuric agent used to inhibit thrombotic and embolic processes and to manage the chronic phases of gout .
OrphenadrineA muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort.
ChlormezanoneUsed in the management of anxiety and in the treatment of muscle spasm.
TubocurarineTubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to...
DantroleneA direct-acting skeletal muscle relaxant used for the treatment of management of the fulminant hypermetabolism of skeletal muscle leading to malignant hyperthermia crisis.
MivacuriumA short-acting non-depolarizing neuromuscular blocking agent used to induce anesthesia during intubation and promote skeletal muscle relaxation during surgery or mechanical ventilation.
LumiracoxibFor the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults.
GlucosamineGlucosamine is usually used in the treatment of osteoarthritis, although its efficacy is still in question.
PancuroniumA neuromuscular blocker used as an adjunct to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
PipecuroniumA nondepolarizing neuromuscular blocking agent used to relax muscles during anesthesia and surgical procedures.
VecuroniumA nondepolarizing neuromuscular blocking agent used to relax muscles or as an adjunct in general anesthesia during surgical procedures.
CalciumA mineral found in over-the-counter supplements or prescription formulations used for the treatment of specific medical conditions related to calcium deficiency.
ColchicineAn alkaloid used in the symptomatic relief of pain in attacks of gout and to treat the inflammatory symptoms of Familial Mediterranean Fever (FMF).
AlfacalcidolA vitamin D analogue used for the management of hypocalcemia, secondary hyperparathyroidism, and osteodystrophy in patients with chronic renal failure.
Tiaprofenic acidA nonsteroidal anti-inflammatory (NSAID) used to manage inflammation and analgesia associated with rheumatoid arthritis and osteoarthritis.
EtoricoxibFor the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.
Flufenamic acidAn anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. (From Martindale, The Extra Pharmacopoeia, 30th...
OxyphenbutazoneA nonsteroidal anti-inflammatory drug (NSAID) no longer commonly used for the symptomatic relief of musculoskeletal pain.
Niflumic acidUsed in the treatment of rheumatoid arthritis.
NimesulideFor the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.
BenoxaprofenThe use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets...
ZomepiracZomepirac was indicated for the management of mild to severe pain.
FebuxostatA xanthine oxidase inhibitor used for the management of chronic hyperuricemia in patients with gout.
AtalurenA medication used for the treatment of Duchenne muscular dystrophy.
TolperisoneInvestigated for use/treatment in neurologic disorders, spinal cord injuries, muscle spasm, back pain, and multiple sclerosis.
DenosumabA RANK ligand (RANKL) inhibitor used for the management of osteoporosis in patients at high risk for bone fractures.
NaproxcinodInvestigated for use/treatment in pain (acute or chronic), inflammatory disorders (unspecified), osteoarthritis, and arthritis and arthritic pain.
LornoxicamFor the treatment of acute mild to moderate pain, as well as pain and inflammation of the joints caused by certain types of rheumatic diseases.
AceclofenacAceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
ChymopapainChymopapain is indicated for the development of chemonucleolysis which is used for the digestion of the nucleus pulposus in patients with disc herniation confirmed by myelography. A disc herniation occurs...
AzapropazoneNot Available
FelbinacNot Available
ParecoxibA selective COX-2 inhibitor and NSAID used for the short-term management of perioperative pain.
KebuzoneKebuzone (also known as ketophenylbutazone ) is a non-steroidal anti-inflammatory drug.
IndoprofenA drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.
IbuproxamIbuproxam is a non steroidal anti-inflammatory drug (NSAID).
FenbufenFenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is...
EtofenamateEtofenamate is used to treat muscle and joint paint. It is a non-steroidal anti-inflammatory drug (NSAID).
EperisoneEperisone is an antispasmodic drug which relaxes both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression...
ZucapsaicinA topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients.
AurothioglucoseA gold compound used in the treatment of rheumatoid arthritis.
PegloticaseA recombinant uricase used for the treatment of chronic gout in adult patients refractory to conventional therapy.
DexibuprofenFor more information, refer to ibuprofen.
DexketoprofenFor short-term treatment of mild to moderate pain, including dysmenorrhoea, musculoskeletal pain and toothache .
DroxicamDroxicam is an NSAID previously used for the treatment of inflammation and rheumatoid arthritis .
Tolfenamic acidIn the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults.
Strontium ranelateA medication used for the management of severe osteoporosis in high-risk postmenopausal women and adult men.
Sodium aurothiomalateA disease-modifying antirheumatic drug (DMARD) indicated for the symptomatic treatment of arthritis.
MorniflumateMorniflumate is indicated for the treatment of inflammatory conditions affecting the airways, ENT system, urogenital tract and bone and joint systems in adults. In Italy, morniflumate is also indicated for...
Chondroitin sulfateChondroitin sulfate, used with glucosamine, is indicated to alleviate pain and inflammation from primary osteoarthritis. This supplement is reported to improve joint function and slow disease progression. Osteoarthritis is characterized...
LesinuradA uric acid 1 transporter inhibitor typically used in combination with a xanthine oxidase inhibitor to treat hyperuricemia associated with gout in patients with inadequate control of uric acid levels with xanthine oxidase inhibitor monotherapy.
ThiocolchicosideThiocolchicoside is a skeletal muscle-relaxant drug used in the treatment of orthopedic, traumatic and rheumatologic disorders . It is indicated as an adjuvant drug in the treatment of painful muscle...
Eptotermin AlfaA bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin Alfa is an ingredient in...
Dibotermin alfaindicated for the treatment of acute tibia fractures in adults, as an adjunct to standard care using open fracture reduction and intramedullary unreamed nail fixation [FDA Label]. indicated for single-level...
DiacereinFor the treatment of osteoarthritis affecting the hip or knee .
BucillamineBucillamine has been used in trials studying the treatment and prevention of Gout and Rheumatoid Arthritis.
BenzbromaroneBenzbromarone has been used in trials studying the basic science and treatment of Heart Failure, Hyperuricemia, Chronic Kidney Disease, Abnormal Renal Function, and Gout and Asymptomatic Hyperuricemia.
AlclofenacAlclofenac is indicated in rheumatology, in particular for the treatment of rheumatoid arthritis, ankylosing spondylitis and, as an analgesic, in painful arthritic pathologies.
FentiazacNot Annotated
SuxibuzoneNot Annotated
BumadizoneBumadizone has been approved for use in Germany and Austria, it is a drug with anti-inflammatory, antipyretic, and analgesic properties, and was marketed for the treatment of both rheumatoid arthritis...
AtracuriumNot Annotated
IdrocilamideNot Annotated
FebarbamateNot Annotated
OxametacinNot Annotated
AlminoprofenAlminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid class of chemical substances.
TetrazepamNot Annotated
BufexamacAn NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses.
PhenprobamateNot Annotated
StyramateNot Annotated
FeprazoneNot Annotated
DifenpiramideNot Annotated
NifenazoneNot Annotated
FenyramidolNot Annotated
LonazolacNot Annotated
TenidapNot Annotated
ProglumetacinNot Annotated
IsobromindioneNot Annotated
CinchophenNot Annotated
MephenesinA cresol glyceryl ether used to treat muscle spasticity in Parkinson's and Multiple Sclerosis.
GallamineNot Annotated
OxycinchophenNot Annotated
IpriflavoneNot Annotated
MofebutazoneNot Annotated
PridinolNot Annotated
AlcuroniumA non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant.
ProquazoneNot Annotated
DrisapersenNot Annotated
HydroquinineNot Annotated
PirprofenNot Annotated
Sodium aurotiosulfateNot Annotated
Fazadinium bromideNot Annotated
AurotioprolNot Annotated
AcemetacinAcemetacin is not FDA, Canada or EMA approved, but in the countries where it is marketed it is indicated for the symptomatic treatment of pain and swelling in acute inflammation...
TisopurineNot Annotated
Collagenase clostridium histolyticumA collagenase enzyme used to promote debridement of necrotic tissue in burns and skin ulcers as well as to treat Dupuytren's contracture and Peyronie's disease.
IndomethacinA nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
KetorolacAn NSAID used to treat moderate to severe pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders, and headaches.
QuinineAn alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
CelecoxibAn NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis.
DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
FlurbiprofenAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
EsomeprazoleA proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion.
NaproxenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
TolazolineA vasodilator used to treat pulmonary artery anomalies.
MisoprostolA prostaglandin E1 analogue used to reduce the risk of NSAID-induced gastric ulcers.
Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
ProbenecidA medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia.
RabeprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
CapsaicinA topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain.
Hyaluronic acidUsed to treat knee pain in patients with joint inflammation (osteoarthritis). It is usually used in patients who have not responded to other treatments such as acetaminophen, exercise, or physical...
BenzydamineA locally-acting NSAID indicated for the symptomatic relief of pain in acute sore throat and for the symptomatic relief of oropharyngeal mucositis caused by radiation therapy.
TrypsinTrypsin is a serine protease that plays an essential role in protein hydrolysis and absorption in mammals. When converted from its zymogen trypsinogen, trypsin is available as an active peptide...
Aluminum chlorohydrateA compound used as an antiperspirant.
BromelainsBromelain is a protease enzyme derived from the stems of pineapples that is composed of a mixture of different thiol endopeptidases and other components like phosphatase, glucosidase, peroxidase, cellulase, escharase,...
FlunoxaprofenNot Annotated
OxaceprolNot Annotated
BendazacPrior to the withdrawal of bendazac from various international regions of use due to concerns for hepatotoxicity [A39891, A39892, A39893, L4778] the chemical had demonstrated potential usefulness predominantly as the...
DipyrocetylNot Annotated
EteplirsenAn antisense oligonucleotide used to treat Duchenne muscular dystrophy (DMD) only in patients who are confirmed to have a specific type of mutation.
Aceneuramic acidAceneuramic acid has been used in trials studying the treatment of Distal Myopathy, Nonaka Type, Hereditary Inclusion Body Myopathy, and Distal Myopathy With Rimmed Vacuoles.
RomosozumabA monoclonal antibody used to treat osteoporosis in postmenopausal women at high risk of fracture, patients who are intolerant of other treatments, or patients who have failed other treatments.
PolmacoxibPolmacoxib has been used in trials studying the treatment of Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis, Knee, Localized Primary Osteoarthritis of Hip, and Localized Primary Osteoarthritis of Knee.
NusinersenA medication used to treat spinal muscular atrophy.
BurosumabA fibroblast growth factor 23 blocking antibody used to treat X-linked hypophosphatemia.
Drugs & Drug Targets
DrugTargetType
MetocurineNeuronal acetylcholine receptor subunit alpha-2target
MetocurineMuscarinic acetylcholine receptor M2target
Botulinum Toxin Type BVesicle-associated membrane protein 1target
Botulinum Toxin Type BVesicle-associated membrane protein 2target
Botulinum Toxin Type BSynaptotagmin-2target
RasburicaseUric acidtarget
Botulinum toxin type ASynaptosomal-associated protein 25target
Botulinum toxin type ARho-related GTP-binding protein RhoBtarget
CholecalciferolVitamin D-binding proteincarrier
CholecalciferolCholesterol side-chain cleavage enzyme, mitochondrialenzyme
CholecalciferolVitamin D 25-hydroxylaseenzyme
CholecalciferolSterol 26-hydroxylase, mitochondrialenzyme
CholecalciferolCytochrome P450 2J2enzyme
CholecalciferolCytochrome P450 3A4enzyme
CholecalciferolVitamin D3 receptortarget
CholecalciferolCytochrome P450 1A1enzyme
CholecalciferolCytochrome P450 2C8enzyme
BaclofenGamma-aminobutyric acid type B receptor subunit 1target
BaclofenGamma-aminobutyric acid type B receptor subunit 2target
SuccinylcholineMuscarinic acetylcholine receptor M1target
SuccinylcholineCholinesteraseenzyme
SuccinylcholineMuscarinic acetylcholine receptor M2target
SuccinylcholineMuscarinic acetylcholine receptor M3target
SuccinylcholineAlpha-7 nicotinic cholinergic receptor subunittarget
SuccinylcholineNeuronal acetylcholine receptor subunit alpha-10target
Pamidronic acidFarnesyl pyrophosphate synthasetarget
Pamidronic acidHydroxylapatitetarget
Pamidronic acidGeranylgeranyl pyrophosphate synthasetarget
Pamidronic acidCaspase-3target
Pamidronic acidCaspase-9target
ChlorzoxazoneCalcium-activated potassium channel subunit alpha-1target
ChlorzoxazoneCytochrome P450 2E1enzyme
ChlorzoxazoneCytochrome P450 1A2enzyme
ChlorzoxazoneCytochrome P450 2A6enzyme
ChlorzoxazoneCytochrome P450 1A1enzyme
ChlorzoxazoneCytochrome P450 2D6enzyme
ChlorzoxazoneCytochrome P450 3A4enzyme
CarisoprodolCytochrome P450 2C19enzyme
CarisoprodolGamma-aminobutyric acid receptor subunit alpha-1target
CarisoprodolGamma-aminobutyric acid receptor subunit beta-2target
CarisoprodolGamma-aminobutyric acid receptor subunit gamma-2target
CarisoprodolGamma-aminobutyric acid receptor subunit alpha-5target
CarisoprodolGamma-aminobutyric acid receptor subunit alpha-3target
Zoledronic acidFarnesyl pyrophosphate synthasetarget
Zoledronic acidGeranylgeranyl pyrophosphate synthasetarget
Zoledronic acidHydroxylapatitetarget
Zoledronic acidMultidrug resistance-associated protein 1transporter
MethocarbamolCarbonic anhydrase 1target
AllopurinolXanthine dehydrogenase/oxidasetarget
AllopurinolSolute carrier family 22 member 8transporter
AllopurinolSolute carrier family 22 member 7transporter
AllopurinolAldehyde oxidaseenzyme
AllopurinolXanthine dehydrogenase/oxidaseenzyme
AllopurinolATP-binding cassette sub-family G member 2transporter
AllopurinolSolute carrier family 22 member 2transporter
NabumetoneProstaglandin G/H synthase 1target
NabumetoneProstaglandin G/H synthase 2target
NabumetoneMyeloperoxidaseenzyme
NabumetoneCytochrome P450 1A2enzyme
NabumetoneCytochrome P450 2C9enzyme
NabumetoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
NabumetoneAldo-keto reductase family 1 member C1enzyme
NabumetoneAldo-keto reductase family 1 member C2enzyme
NabumetoneAldo-keto reductase family 1 member C4enzyme
NabumetoneSerum albumincarrier
TenoxicamProstaglandin G/H synthase 1target
TenoxicamProstaglandin G/H synthase 2target
TenoxicamCytochrome P450 2C9enzyme
TenoxicamSolute carrier family 22 member 8transporter
TolmetinProstaglandin G/H synthase 1target
TolmetinProstaglandin G/H synthase 2target
TolmetinSolute carrier family 22 member 6transporter
TolmetinTryptophan 2,3-dioxygenaseenzyme
TolmetinMyeloperoxidaseenzyme
TolmetinSerum albumincarrier
RofecoxibProstaglandin G/H synthase 2target
RofecoxibElastintarget
RofecoxibCytochrome P450 3A4enzyme
RofecoxibCytochrome P450 1A2enzyme
RofecoxibMultidrug resistance-associated protein 4transporter
RofecoxibProstaglandin G/H synthase 1enzyme
RofecoxibCytochrome P450 2C8enzyme
RofecoxibCytochrome P450 2C9enzyme
PiroxicamProstaglandin G/H synthase 1target
PiroxicamProstaglandin G/H synthase 2target
PiroxicamSerum albumincarrier
PiroxicamCytochrome P450 2C9enzyme
PiroxicamSolute carrier family 22 member 6transporter
PiroxicamSolute carrier family 22 member 8transporter
PiroxicamSolute carrier family 22 member 11transporter
PiroxicamCytochrome P450 2C8enzyme
PiroxicamSolute carrier organic anion transporter family member 2B1transporter
CisatracuriumNeuronal acetylcholine receptor subunit alpha-2target
FenoprofenProstaglandin G/H synthase 1target
FenoprofenProstaglandin G/H synthase 2target
FenoprofenSerum albumincarrier
FenoprofenPeroxisome proliferator-activated receptor alphatarget
FenoprofenPeroxisome proliferator-activated receptor gammatarget
ValdecoxibProstaglandin G/H synthase 2target
ValdecoxibCytochrome P450 2C9enzyme
ValdecoxibCytochrome P450 3A4enzyme
ValdecoxibUDP-glucuronosyltransferase 1-9enzyme
ValdecoxibCarbonic anhydrase 2target
ValdecoxibCarbonic anhydrase 3target
SulindacProstaglandin G/H synthase 2target
SulindacAldose reductasetarget
SulindacProstaglandin G/H synthase 1target
SulindacMitogen-activated protein kinase 3target
SulindacPeroxisome proliferator-activated receptor deltatarget
SulindacProstaglandin D2 receptor 2target
SulindacSerum albumincarrier
SulindacSolute carrier family 22 member 6transporter
SulindacCytochrome P450 1A1enzyme
SulindacAldo-keto reductase family 1 member B10target
Alendronic acidFarnesyl pyrophosphate synthasetarget
Alendronic acidTyrosine-protein phosphatase non-receptor type 4target
Alendronic acidReceptor-type tyrosine-protein phosphatase Starget
Alendronic acidReceptor-type tyrosine-protein phosphatase epsilontarget
Alendronic acidV-type proton ATPase catalytic subunit Atarget
Alendronic acidHydroxylapatitetarget
TizanidineAlpha-2 adrenergic receptorstarget
TizanidineCytochrome P450 1A2enzyme
TizanidineNischarintarget
TizanidineAlpha-1 adrenergic receptorstarget
IbandronateFarnesyl pyrophosphate synthasetarget
IbandronateHydroxylapatitetarget
IbandronateGeranylgeranyl pyrophosphate synthasetarget
Clodronic acidADP/ATP translocase 2target
Clodronic acidADP/ATP translocase 1target
Clodronic acidADP/ATP translocase 3target
Clodronic acidHydroxylapatitetarget
Clodronic acidProstaglandin G/H synthase 2enzyme
RocuroniumNeuronal acetylcholine receptor subunit alpha-2target
RocuroniumMuscarinic acetylcholine receptor M2target
Rocuronium5-hydroxytryptamine receptor 3Atarget
RocuroniumSolute carrier family 22 member 1transporter
RocuroniumSolute carrier organic anion transporter family member 1A2transporter
EtodolacProstaglandin G/H synthase 1target
EtodolacProstaglandin G/H synthase 2target
EtodolacCytochrome P450 2C9enzyme
EtodolacUDP-glucuronosyltransferase 1-9enzyme
EtodolacRetinoic acid receptor RXR-alphatarget
EtodolacSerum albumincarrier
EtodolacSolute carrier family 22 member 6transporter
EtodolacUDP-glucuronosyltransferase 1-3enzyme
EtodolacUDP-glucuronosyltransferase 1-10enzyme
EtodolacUDP-glucuronosyltransferase 2B7enzyme
Mefenamic acidProstaglandin G/H synthase 2target
Mefenamic acidProstaglandin G/H synthase 1target
Mefenamic acidCytochrome P450 2C9enzyme
Mefenamic acidCytochrome P450 2C8enzyme
Mefenamic acidSerum albumincarrier
Mefenamic acidUDP-glucuronosyltransferase 1-9enzyme
PhenylbutazoneProstaglandin G/H synthase 2target
PhenylbutazoneProstacyclin synthasetarget
PhenylbutazoneCytochrome P450 2C9enzyme
PhenylbutazoneSolute carrier family 22 member 6transporter
PhenylbutazoneSolute carrier family 22 member 8transporter
PhenylbutazoneSolute carrier family 22 member 11transporter
PhenylbutazoneProstaglandin G/H synthase 1target
PhenylbutazoneCytochrome P450 3A4enzyme
MeloxicamProstaglandin G/H synthase 2target
MeloxicamCytochrome P450 2C9enzyme
MeloxicamProstaglandin G/H synthase 1target
MeloxicamCytochrome P450 3A4enzyme
MeloxicamMultidrug resistance-associated protein 4transporter
Meloxicam6-phosphogluconate dehydrogenase, decarboxylatingenzyme
MeloxicamCytochrome P450 2C8enzyme
MeloxicamSerum albumincarrier
MeloxicamHuman vesicular glutamate transporterstransporter
PenicillamineSolute carrier organic anion transporter family member 1B1transporter
PenicillamineCoppertarget
SuprofenProstaglandin G/H synthase 1target
SuprofenProstaglandin G/H synthase 2target
SuprofenCytochrome P450 2C9enzyme
SuprofenUDP-glucuronosyltransferase 1-1enzyme
SuprofenSolute carrier family 22 member 12transporter
SuprofenUDP-glucuronosyltransferase 2B7enzyme
SuprofenSerum albumincarrier
Risedronic acidFarnesyl pyrophosphate synthasetarget
Risedronic acidHydroxylapatitetarget
Risedronic acidProstaglandin G/H synthase 2enzyme
Cyclobenzaprine5-hydroxytryptamine receptor 2Atarget
CyclobenzaprineCytochrome P450 1A2enzyme
CyclobenzaprineCytochrome P450 3A4enzyme
CyclobenzaprineCytochrome P450 2D6enzyme
CyclobenzaprineSerum albumincarrier
CyclobenzaprineUDP-glucuronosyltransferase 1-4enzyme
CyclobenzaprineUDP-glucuronosyltransferase 2B10enzyme
Cyclobenzaprine5-hydroxytryptamine receptor 2Btarget
Cyclobenzaprine5-hydroxytryptamine receptor 2Ctarget
Cyclobenzaprine5-hydroxytryptamine receptor 7target
Cyclobenzaprine5-hydroxytryptamine receptor 6target
CyclobenzaprineSodium-dependent serotonin transportertarget
CyclobenzaprineSodium-dependent noradrenaline transportertarget
CyclobenzaprineToll-like receptor 4target
CyclobenzaprineAldehyde oxidasetarget
Meclofenamic acidProstaglandin G/H synthase 1target
Meclofenamic acidProstaglandin G/H synthase 2target
Meclofenamic acidArachidonate 5-lipoxygenasetarget
Meclofenamic acidSolute carrier family 22 member 6transporter
Meclofenamic acidSolute carrier organic anion transporter family member 1C1transporter
Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 2target
Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 3target
Meclofenamic acidThyroxine-binding globulincarrier
HexafluroniumCholinesterasetarget
OxaprozinProstaglandin G/H synthase 2target
OxaprozinProstaglandin G/H synthase 1target
AuranofinInhibitor of nuclear factor kappa-B kinase subunit betatarget
AuranofinSerum albumincarrier
AuranofinPeroxiredoxin-5, mitochondrialtarget
KetoprofenProstaglandin G/H synthase 1target
KetoprofenProstaglandin G/H synthase 2target
KetoprofenC-X-C chemokine receptor type 1target
KetoprofenSerum albumincarrier
KetoprofenMultidrug resistance-associated protein 4transporter
KetoprofenSolute carrier organic anion transporter family member 1A2transporter
KetoprofenSolute carrier family 22 member 6transporter
KetoprofenSolute carrier family 22 member 8transporter
KetoprofenSolute carrier family 22 member 11transporter
KetoprofenSolute carrier family 22 member 7transporter
KetoprofenCytochrome P450 2C9enzyme
KetoprofenCytochrome P450 2C8enzyme
KetoprofenUDP-glucuronosyltransferase 1-1enzyme
Etidronic acidHydroxylapatitetarget
Etidronic acidReceptor-type tyrosine-protein phosphatase Starget
Etidronic acidV-type proton ATPase catalytic subunit Atarget
Etidronic acidADP/ATP translocase 1target
Etidronic acidADP/ATP translocase 2target
Etidronic acidADP/ATP translocase 3target
Dimethyl sulfoxideTransthyretincarrier
Dimethyl sulfoxideCytochrome P450 2C19enzyme
Dimethyl sulfoxideCytochrome P450 2D6enzyme
Dimethyl sulfoxideCytochrome P450 3A4enzyme
Tiludronic acidTyrosine-protein phosphatase non-receptor type 12target
Tiludronic acidV-ATPase Subunitstarget
Tiludronic acidHydroxylapatitetarget
Tiludronic acidAdenosine triphosphate (ATP)target
Tiludronic acidSerum albumincarrier
Tiludronic acidTyrosine-protein phosphatase non-receptor type 6target
Tiludronic acidReceptor-type tyrosine-protein phosphatase epsilontarget
DoxacuriumNeuronal acetylcholine receptor subunit alpha-2target
DoxacuriumMuscarinic acetylcholine receptor M2target
DoxacuriumCholinesteraseenzyme
SulfinpyrazoneMultidrug resistance-associated protein 1target
SulfinpyrazoneCanalicular multispecific organic anion transporter 1target
SulfinpyrazoneFatty acid-binding protein, intestinalcarrier
SulfinpyrazoneCytochrome P450 2C9enzyme
SulfinpyrazoneCanalicular multispecific organic anion transporter 2transporter
SulfinpyrazoneMultidrug resistance-associated protein 4transporter
SulfinpyrazoneMultidrug resistance-associated protein 5transporter
SulfinpyrazoneMultidrug resistance-associated protein 6transporter
SulfinpyrazoneMultidrug resistance-associated protein 1transporter
SulfinpyrazoneCanalicular multispecific organic anion transporter 1transporter
SulfinpyrazoneCytochrome P450 3A4enzyme
SulfinpyrazoneCytochrome P450 2B6enzyme
SulfinpyrazoneCytochrome P450 2C8enzyme
SulfinpyrazoneSolute carrier family 22 member 12target
SulfinpyrazoneNuclear receptor subfamily 1 group I member 2target
SulfinpyrazoneBile salt export pumptransporter
OrphenadrineGlutamate receptor ionotropic, NMDA 1target
OrphenadrineGlutamate receptor ionotropic, NMDA 2Dtarget
OrphenadrineGlutamate receptor ionotropic, NMDA 3Btarget
OrphenadrineGlutamate receptor ionotropic, NMDA 3Atarget
OrphenadrineHistamine H1 receptortarget
OrphenadrineCytochrome P450 2B6enzyme
OrphenadrineCytochrome P450 2E1enzyme
OrphenadrineCytochrome P450 3A4enzyme
OrphenadrineSodium-dependent noradrenaline transportertarget
OrphenadrineSodium channel protein type 10 subunit alphatarget
OrphenadrineCytochrome P450 1A2enzyme
OrphenadrineCytochrome P450 2D6enzyme
ChlormezanoneTranslocator proteintarget
TubocurarineNeuronal acetylcholine receptor subunit alpha-2target
TubocurarineAcetylcholinesterasetarget
Tubocurarine5-hydroxytryptamine receptor 3Atarget
TubocurarineSolute carrier family 22 member 1transporter
TubocurarineSolute carrier family 22 member 2transporter
TubocurarineNeuronal acetylcholine receptor subunit alpha-7target
TubocurarineCholinesteraseenzyme
DantroleneRyanodine receptor 1target
DantroleneThyroxine-binding globulincarrier
MivacuriumNeuronal acetylcholine receptor subunit alpha-2target
MivacuriumMuscarinic acetylcholine receptor M2target
MivacuriumMuscarinic acetylcholine receptor M3target
MivacuriumCholinesterasetarget
LumiracoxibProstaglandin G/H synthase 2target
LumiracoxibProstaglandin G/H synthase 1target
LumiracoxibCytochrome P450 2C9enzyme
LumiracoxibCytochrome P450 2C19enzyme
LumiracoxibUDP-glucuronosyltransferase 1-9enzyme
LumiracoxibCytochrome P450 1A2enzyme
GlucosamineTumor necrosis factortarget
GlucosamineInterferon gammatarget
GlucosamineMatrix metalloproteinase-9target
GlucosamineChitosanasetarget
GlucosamineNuclear factor NF-kappa-B p100 subunittarget
PancuroniumNeuronal acetylcholine receptor subunit alpha-2target
PancuroniumCholinesteraseenzyme
PancuroniumMuscarinic acetylcholine receptor M2target
PancuroniumMuscarinic acetylcholine receptor M3target
PancuroniumSolute carrier family 22 member 1transporter
PancuroniumSolute carrier family 22 member 2transporter
PipecuroniumNeuronal acetylcholine receptor subunit alpha-2target
PipecuroniumMuscarinic acetylcholine receptor M2target
PipecuroniumMuscarinic acetylcholine receptor M3target
PipecuroniumCholinesteraseenzyme
VecuroniumP-glycoprotein 1transporter
VecuroniumNeuronal acetylcholine receptor subunit alpha-2target
CalciumProtein S100-Btarget
CalciumCalpastatintarget
CalciumCartilage oligomeric matrix proteintarget
CalciumCalmodulintarget
CalciumSpectrin beta chain, non-erythrocytic 1target
CalciumVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
CalciumTroponin C, skeletal muscletarget
CalciumTroponin C, slow skeletal and cardiac musclestarget
CalciumCalcium-transporting ATPase type 2C member 1target
CalciumAmiloride-sensitive amine oxidase [copper-containing]target
CalciumProtein S100-A13target
CalciumAlkaline phosphatase, placental typetarget
CalciumProtein S100-A8target
CalciumProtein S100-A9target
CalciumProtein S100-A2target
CalciumCeruloplasmintarget
CalciumBone morphogenetic protein 4target
CalciumMatrix Gla proteintarget
CalciumProtocadherin-19target
CalciumProgrammed cell death protein 6target
ColchicineTubulin beta chaintarget
ColchicineCytochrome P450 3A4enzyme
ColchicineP-glycoprotein 1transporter
ColchicineCytochrome P450 2B6enzyme
ColchicineCytochrome P450 2C8enzyme
ColchicineCytochrome P450 2E1enzyme
ColchicineSerum albumincarrier
AlfacalcidolVitamin D-binding proteincarrier
AlfacalcidolVitamin D3 receptortarget
Alfacalcidol25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialtarget
AlfacalcidolRetinoic acid receptor RXR-alphatarget
Tiaprofenic acidProstaglandin G/H synthase 2target
Tiaprofenic acidProstaglandin G/H synthase 1target
EtoricoxibProstaglandin G/H synthase 2target
EtoricoxibCytochrome P450 3A4enzyme
EtoricoxibCytochrome P450 2C9enzyme
EtoricoxibCytochrome P450 2D6enzyme
EtoricoxibCytochrome P450 1A2enzyme
EtoricoxibCytochrome P450 2C19enzyme
EtoricoxibCytochrome P450 2E1enzyme
Flufenamic acidAldo-keto reductase family 1 member C3target
Flufenamic acidTransthyretincarrier
Flufenamic acidProstaglandin G/H synthase 2target
Flufenamic acidProstaglandin G/H synthase 1target
Flufenamic acidSolute carrier family 22 member 6transporter
Flufenamic acidAndrogen receptortarget
Flufenamic acidPeroxisome proliferator-activated receptor alphatarget
Flufenamic acidPeroxisome proliferator-activated receptor gammatarget
OxyphenbutazoneGroup IIE secretory phospholipase A2target
OxyphenbutazoneSerum albumincarrier
OxyphenbutazoneSolute carrier family 22 member 6transporter
Niflumic acidPhospholipase A2target
Niflumic acidChloride channel protein ClC-Katarget
Niflumic acidMonocarboxylate transporter 2transporter
Niflumic acidMonocarboxylate transporter 1transporter
Niflumic acidProstaglandin G/H synthase 2target
Niflumic acidProstaglandin G/H synthase 1target
Niflumic acidCytosolic phospholipase A2target
Niflumic acidUDP-glucuronosyltransferase 1-9target
Niflumic acidUDP-glucuronosyltransferase 1-9enzyme
NimesulideProstaglandin G/H synthase 2target
NimesulideGroup IIE secretory phospholipase A2target
NimesulideLactotransferrintarget
NimesulideCytochrome P450 3A4enzyme
ZomepiracProstaglandin D2 receptor 2target
ZomepiracCytochrome P450 3A4enzyme
ZomepiracSerum albumincarrier
FebuxostatXanthine dehydrogenase/oxidasetarget
AtalurenUDP-glucuronosyltransferase 1-9enzyme
AtalurenSolute carrier family 22 member 6enzyme
AtalurenSolute carrier family 22 member 8enzyme
AtalurenSolute carrier organic anion transporter family member 1B3enzyme
TolperisoneCytochrome P450 1A2enzyme
DenosumabTumor necrosis factor ligand superfamily member 11target
LornoxicamCytochrome P450 2C9enzyme
LornoxicamProstaglandin G/H synthase 1target
LornoxicamProstaglandin G/H synthase 2target
AceclofenacCytochrome P450 2C9enzyme
AceclofenacProstaglandin G/H synthase 2target
AceclofenacProstaglandin G/H synthase 1target
ChymopapainBone marrow proteoglycantarget
AzapropazoneSerum albumincarrier
FelbinacCathepsin L1target
ParecoxibLactotransferrintarget
ParecoxibProstaglandin G/H synthase 2target
ParecoxibCytochrome P450 3A4enzyme
ParecoxibCytochrome P450 2C9enzyme
EtofenamateThyroxine-binding globulincarrier
EperisoneCytochrome P450 3A4enzyme
ZucapsaicinTransient receptor potential cation channel subfamily V member 1target
ZucapsaicinCytochrome P450 1A2enzyme
ZucapsaicinCytochrome P450 2C19enzyme
ZucapsaicinCytochrome P450 2C9enzyme
ZucapsaicinCytochrome P450 2E1enzyme
AurothioglucoseAdenylate cyclase type 1target
AurothioglucoseAdenylate cyclase type 2target
AurothioglucoseAdenylate cyclase type 5target
PegloticaseUric acidtarget
DexibuprofenProstaglandin G/H synthase 1target
DexibuprofenProstaglandin G/H synthase 2target
DexibuprofenApoptosis regulator Bcl-2target
DexibuprofenThrombomodulintarget
DexibuprofenTissue-type plasminogen activatortarget
DexibuprofenFatty acid-binding protein, intestinaltarget
DexibuprofenPeroxisome proliferator-activated receptor gammatarget
DexibuprofenCystic fibrosis transmembrane conductance regulatortarget
DexibuprofenCytochrome P450 2C9enzyme
DexibuprofenSerum albumincarrier
DexibuprofenMultidrug resistance-associated protein 4transporter
DexibuprofenMultidrug resistance-associated protein 1transporter
DexibuprofenSolute carrier organic anion transporter family member 1A2transporter
DexibuprofenSolute carrier family 22 member 6transporter
DexibuprofenSolute carrier family 22 member 8transporter
DexibuprofenSolute carrier family 22 member 11transporter
DexibuprofenSolute carrier organic anion transporter family member 2B1transporter
DexibuprofenP-glycoprotein 1transporter
DexibuprofenUDP-glucuronosyltransferase 1-1enzyme
DexibuprofenUDP-glucuronosyltransferase 1-3enzyme
DexibuprofenUDP-glucuronosyltransferase 1-9enzyme
DexibuprofenUDP-glucuronosyltransferase 2B4enzyme
DexibuprofenUDP-glucuronosyltransferase 2B7enzyme
DexibuprofenCytochrome P450 2C8enzyme
DexibuprofenCytochrome P450 2C19enzyme
DexibuprofenSolute carrier family 15 member 1target
DexibuprofenPeroxisome proliferator-activated receptor alphatarget
DexibuprofenPlatelet glycoprotein Ib alpha chaintarget
DexibuprofenProtein S100-A7target
DexibuprofenAlpha-methylacyl-CoA racemaseenzyme
DexketoprofenProstaglandin G/H synthase 1target
DexketoprofenProstaglandin G/H synthase 2target
DexketoprofenProstaglandin G/H synthase 1enzyme
DexketoprofenProstaglandin G/H synthase 2enzyme
DroxicamProstaglandin G/H synthase 1target
DroxicamProstaglandin G/H synthase 2target
Tolfenamic acidProstaglandin G/H synthase 1target
Tolfenamic acidProstaglandin G/H synthase 2target
Tolfenamic acidCytochrome P450 3A4enzyme
Sodium aurothiomalateUDP-glucuronosyltransferase 1-1enzyme
MorniflumateArachidonate 5-lipoxygenasetarget
MorniflumateProstaglandin G/H synthase 2target
MorniflumateArachidonate 5-lipoxygenaseenzyme
MorniflumateProstaglandin G/H synthase 2enzyme
MorniflumateLeukotriene B4 receptor 1target
MorniflumateThromboxane A2 receptortarget
MorniflumateUDP-glucuronosyltransferase 1-9enzyme
Chondroitin sulfateBrain-derived neurotrophic factortarget
Chondroitin sulfateGlial cell line-derived neurotrophic factortarget
Chondroitin sulfateVascular endothelial growth factor Atarget
Chondroitin sulfateC-C motif chemokine 2target
Chondroitin sulfateBeta-glucuronidaseenzyme
Chondroitin sulfateBeta-hexosaminidase subunit betaenzyme
Chondroitin sulfateN-acetylgalactosamine-6-sulfataseenzyme
Chondroitin sulfateIduronate 2-sulfataseenzyme
Chondroitin sulfateAlpha-L-iduronidaseenzyme
Chondroitin sulfateArylsulfatase Benzyme
LesinuradSolute carrier family 22 member 12target
LesinuradSolute carrier family 22 member 11target
LesinuradCytochrome P450 2C9enzyme
LesinuradCytochrome P450 3A4enzyme
ThiocolchicosideGABA(A) Receptortarget
ThiocolchicosideGlycine receptor subunit alpha-1target
ThiocolchicosideTumor necrosis factor ligand superfamily member 11target
Dibotermin alfaBone morphogenetic protein receptor type-1Atarget
Dibotermin alfaBone morphogenetic protein receptor type-2target
DiacereinOxysterols receptor LXR-alphatarget
DiacereinOxysterols receptor LXR-betatarget
DiacereinArylamine N-acetyltransferasetarget
DiacereinArachidonate 5-lipoxygenasetarget
DiacereinCytochrome P450 1A2target
DiacereinCytochrome P450 3A Subfamilytarget
DiacereinCytochrome P450 2E1target
DiacereinCytochrome P450 2C9target
DiacereinCytochrome P450 2D6target
BenzbromaroneCytochrome P450 2C9target
BenzbromaroneCytochrome P450 2C19target
BenzbromaroneSolute carrier organic anion transporter family member 1B1transporter
BenzbromaroneSolute carrier organic anion transporter family member 2B1transporter
BenzbromaroneBile salt export pumptransporter
BenzbromaroneCytochrome P450 2C19enzyme
AlclofenacProstaglandin G/H synthase 2target
BufexamacProstaglandin G/H synthase 1target
BufexamacProstaglandin G/H synthase 2target
BufexamacHistone deacetylase 6target
BufexamacHistone deacetylase 10target
AcemetacinProstaglandin G/H synthase 1target
AcemetacinProstaglandin G/H synthase 2target
AcemetacinUDP-glucuronosyltransferase 2B7enzyme
AcemetacinMultidrug resistance-associated protein 1transporter
Collagenase clostridium histolyticumCollagen alpha-1(I) chaintarget
Collagenase clostridium histolyticumCollagen alpha-1(II) chaintarget
Collagenase clostridium histolyticumCollagen alpha-1(III) chaintarget
IndomethacinProstaglandin G/H synthase 1target
IndomethacinProstaglandin G/H synthase 2target
IndomethacinCytochrome P450 2C19enzyme
IndomethacinUDP-glucuronosyltransferase 1-9enzyme
IndomethacinPhospholipase A2, membrane associatedtarget
IndomethacinProstaglandin reductase 2target
IndomethacinLactoylglutathione lyasetarget
IndomethacinProstaglandin D2 receptor 2target
IndomethacinPeroxisome proliferator-activated receptor gammatarget
IndomethacinSerum albumincarrier
IndomethacinCanalicular multispecific organic anion transporter 2transporter
IndomethacinMultidrug resistance-associated protein 4transporter
IndomethacinMultidrug resistance-associated protein 6transporter
IndomethacinP-glycoprotein 1transporter
IndomethacinMultidrug resistance-associated protein 1transporter
IndomethacinSolute carrier organic anion transporter family member 1A2transporter
IndomethacinSolute carrier family 22 member 6transporter
IndomethacinSolute carrier family 22 member 8transporter
IndomethacinCanalicular multispecific organic anion transporter 1transporter
IndomethacinATP-binding cassette sub-family C member 11transporter
IndomethacinSolute carrier family 22 member 11transporter
IndomethacinSodium/bile acid cotransportertransporter
IndomethacinSolute carrier family 22 member 7transporter
IndomethacinCytochrome P450 2C9enzyme
IndomethacinUDP-glucuronosyltransferase 1-1enzyme
IndomethacinLiver carboxylesterase 1enzyme
IndomethacinUDP-glucuronosyltransferase 2B7enzyme
IndomethacinPeroxisome proliferator-activated receptor alphatarget
IndomethacinAldo-keto reductase family 1 member C3target
IndomethacinSolute carrier organic anion transporter family member 1B1transporter
IndomethacinBile salt export pumptransporter
KetorolacProstaglandin G/H synthase 1target
KetorolacProstaglandin G/H synthase 2target
KetorolacUDP-glucuronosyltransferase 2B7enzyme
KetorolacCytochrome P450 2C8enzyme
KetorolacCytochrome P450 2C9enzyme
QuininePlatelet glycoprotein IXtarget
QuinineIntermediate conductance calcium-activated potassium channel protein 4target
QuinineCytochrome P450 3A4enzyme
QuinineCytochrome P450 3A5enzyme
QuinineCytochrome P450 1A1enzyme
QuinineCytochrome P450 2D6enzyme
QuinineCytochrome P450 1A2enzyme
QuinineCytochrome P450 2C8enzyme
QuinineCytochrome P450 2C9enzyme
QuinineCytochrome P450 2C19enzyme
QuinineCytochrome P450 2E1enzyme
QuinineCytochrome P450 3A7enzyme
QuinineSolute carrier family 22 member 2transporter
QuinineSolute carrier family 22 member 1transporter
QuinineSolute carrier family 22 member 5transporter
QuinineP-glycoprotein 1transporter
QuinineSolute carrier organic anion transporter family member 1A2transporter
QuinineSolute carrier family 22 member 4transporter
QuinineFe(II)-protoporphyrin IXtarget
QuinineSolute carrier organic anion transporter family member 1B1transporter
CelecoxibProstaglandin G/H synthase 2target
Celecoxib3-phosphoinositide-dependent protein kinase 1target
CelecoxibCytochrome P450 2C9enzyme
CelecoxibCytochrome P450 2D6enzyme
CelecoxibMultidrug resistance-associated protein 4transporter
CelecoxibCytochrome P450 3A4enzyme
CelecoxibCytochrome P450 2C8enzyme
CelecoxibCarbonic anhydrase 2target
CelecoxibCarbonic anhydrase 3target
CelecoxibBile salt export pumptransporter
CelecoxibCadherin-11target
CelecoxibP-glycoprotein 1transporter
CelecoxibATP-binding cassette sub-family G member 2transporter
DiclofenacProstaglandin G/H synthase 1target
DiclofenacProstaglandin G/H synthase 2target
DiclofenacTransthyretincarrier
DiclofenacCytochrome P450 2C9enzyme
DiclofenacCytochrome P450 2C19enzyme
DiclofenacCytochrome P450 1A2enzyme
DiclofenacCytochrome P450 2C8enzyme
DiclofenacSerum albumincarrier
DiclofenacMultidrug resistance-associated protein 4transporter
DiclofenacMultidrug resistance-associated protein 1transporter
DiclofenacSolute carrier family 22 member 6transporter
DiclofenacSolute carrier family 22 member 8transporter
DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DiclofenacSolute carrier family 22 member 11transporter
DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DiclofenacCytochrome P450 3A4enzyme
DiclofenacCytochrome P450 2B6enzyme
DiclofenacCytochrome P450 2C18enzyme
DiclofenacCytochrome P450 2E1enzyme
DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DiclofenacBile salt export pumptransporter
DiclofenacUDP-glucuronosyltransferase 1-3enzyme
DiclofenacUDP-glucuronosyltransferase 1-9enzyme
DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DiclofenacArachidonate 5-lipoxygenaseenzyme
DiclofenacSodium channel protein type 4 subunit alphatransporter
DiclofenacAcid-sensing ion channel 1transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DiclofenacPhospholipase A2, membrane associatedenzyme
DiclofenacP-glycoprotein 1transporter
FlurbiprofenProstaglandin G/H synthase 2target
FlurbiprofenProstaglandin G/H synthase 1target
FlurbiprofenCytochrome P450 2C9enzyme
FlurbiprofenSerum albumincarrier
FlurbiprofenMultidrug resistance-associated protein 4transporter
FlurbiprofenSolute carrier family 22 member 6transporter
FlurbiprofenUDP-glucuronosyltransferase 2B7enzyme
FlurbiprofenUDP-glucuronosyltransferase 1-1enzyme
FlurbiprofenUDP-glucuronosyltransferase 1-3enzyme
FlurbiprofenUDP-glucuronosyltransferase 1-9enzyme
FlurbiprofenUDP-glucuronosyltransferase 2B4enzyme
EsomeprazolePotassium-transporting ATPase alpha chain 1target
EsomeprazoleCytochrome P450 2C19enzyme
EsomeprazoleCytochrome P450 3A4enzyme
EsomeprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
EsomeprazoleP-glycoprotein 1transporter
EsomeprazoleSolute carrier family 22 member 8transporter
NaproxenProstaglandin G/H synthase 1target
NaproxenProstaglandin G/H synthase 2target
NaproxenSerum albumincarrier
NaproxenCytochrome P450 2C9enzyme
NaproxenCytochrome P450 1A2enzyme
NaproxenSolute carrier organic anion transporter family member 1A2transporter
NaproxenSolute carrier family 22 member 6transporter
NaproxenCytochrome P450 2C8enzyme
NaproxenUDP-glucuronosyltransferase 2B7enzyme
NaproxenPeptostreptococcal albumin-binding proteintarget
NaproxenBile salt export pumptransporter
NaproxenP-glycoprotein 1transporter
NaproxenUDP-glucuronosyltransferase 1-3enzyme
NaproxenUDP-glucuronosyltransferase 1-6enzyme
NaproxenUDP-glucuronosyltransferase 1-7enzyme
NaproxenUDP-glucuronosyltransferase 1-8enzyme
NaproxenUDP-glucuronosyltransferase 1-9enzyme
NaproxenUDP-glucuronosyltransferase 1-10enzyme
NaproxenSolute carrier family 22 member 8transporter
TolazolineAlpha-1A adrenergic receptortarget
TolazolineAlpha-2A adrenergic receptortarget
TolazolineHistamine H1 receptortarget
TolazolineHistamine H2 receptortarget
TolazolineAlpha-2C adrenergic receptortarget
TolazolineAlpha-2B adrenergic receptortarget
MisoprostolProstaglandin E2 receptor EP2 subtypetarget
MisoprostolProstaglandin E2 receptor EP3 subtypetarget
MisoprostolProstaglandin E2 receptor EP4 subtypetarget
MisoprostolProstaglandin E2 receptor EP1 subtypetarget
Acetylsalicylic acidProstaglandin G/H synthase 1target
Acetylsalicylic acidProstaglandin G/H synthase 2target
Acetylsalicylic acidAldo-keto reductase family 1 member C1target
Acetylsalicylic acidSolute carrier family 22 member 6transporter
Acetylsalicylic acidP-glycoprotein 1transporter
Acetylsalicylic acidCytochrome P450 2C19enzyme
Acetylsalicylic acidCytochrome P450 2C9enzyme
Acetylsalicylic acid5'-AMP-activated protein kinasetarget
Acetylsalicylic acidEndothelin-1 receptortarget
Acetylsalicylic acidCellular tumor antigen p53target
Acetylsalicylic acid78 kDa glucose-regulated proteintarget
Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
Acetylsalicylic acidCaspase-1target
Acetylsalicylic acidCaspase-3target
Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
Acetylsalicylic acidG1/S-specific cyclin-D1target
Acetylsalicylic acidMyc proto-oncogene proteintarget
Acetylsalicylic acidProliferating cell nuclear antigentarget
Acetylsalicylic acidCyclin Atarget
Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
Acetylsalicylic acidSolute carrier family 22 member 8transporter
ProbenecidSolute carrier family 22 member 8target
ProbenecidSolute carrier family 22 member 11target
ProbenecidSerum albumincarrier
ProbenecidSolute carrier family 22 member 2transporter
ProbenecidSolute carrier family 22 member 1transporter
ProbenecidCanalicular multispecific organic anion transporter 2transporter
ProbenecidMultidrug resistance-associated protein 4transporter
ProbenecidMultidrug resistance-associated protein 5transporter
ProbenecidMonocarboxylate transporter 2transporter
ProbenecidSolute carrier family 22 member 5transporter
ProbenecidMultidrug resistance-associated protein 6transporter
ProbenecidMultidrug resistance-associated protein 1transporter
ProbenecidSolute carrier organic anion transporter family member 1A2transporter
ProbenecidMonocarboxylate transporter 1transporter
ProbenecidSodium/bile acid cotransportertransporter
ProbenecidSolute carrier family 22 member 6transporter
ProbenecidSolute carrier family 22 member 10transporter
ProbenecidSolute carrier family 22 member 8transporter
ProbenecidCanalicular multispecific organic anion transporter 1transporter
ProbenecidATP-binding cassette sub-family C member 11transporter
ProbenecidSolute carrier family 22 member 11transporter
ProbenecidSolute carrier organic anion transporter family member 1C1transporter
ProbenecidSolute carrier family 22 member 7transporter
ProbenecidSolute carrier family 22 member 6target
ProbenecidPannexin-1target
ProbenecidCytochrome P450 2C8enzyme
ProbenecidCytochrome P450 3A4enzyme
ProbenecidSolute carrier family 22 member 12transporter
ProbenecidSolute carrier family 2, facilitated glucose transporter member 9transporter
ProbenecidTaste receptor type 2 member 16target
ProbenecidUDP-glucuronosyltransferase 1-1enzyme
ProbenecidCytochrome P450 2C9enzyme
RabeprazolePotassium-transporting ATPase alpha chain 1target
RabeprazoleCytochrome P450 3A4enzyme
RabeprazoleCytochrome P450 2C19enzyme
RabeprazoleATP-binding cassette sub-family G member 2transporter
RabeprazoleCytochrome P450 1A1enzyme
RabeprazoleCytochrome P450 1A2enzyme
RabeprazoleCytochrome P450 2C9enzyme
RabeprazoleCytochrome P450 2D6enzyme
RabeprazoleCytochrome P450 2C8enzyme
CapsaicinCytochrome P450 3A4enzyme
CapsaicinProstaglandin G/H synthase 2enzyme
CapsaicinMyeloperoxidaseenzyme
CapsaicinCytochrome P450 1A2enzyme
CapsaicinCytochrome P450 2E1enzyme
CapsaicinAmine oxidase [flavin-containing] Aenzyme
CapsaicinDopamine beta-hydroxylaseenzyme
CapsaicinGlutamine synthetaseenzyme
CapsaicinCholinesteraseenzyme
CapsaicinTransient receptor potential cation channel subfamily V member 1target
CapsaicinProhibitin-2target
Hyaluronic acidCD44 antigentarget
Hyaluronic acidIntercellular adhesion molecule 1target
Hyaluronic acidHyaluronan mediated motility receptortarget
Hyaluronic acidNeurocan core proteintarget
Hyaluronic acidVersican core proteintarget
Hyaluronic acidComplement component 1 Q subcomponent-binding protein, mitochondrialtarget
Hyaluronic acidHyaluronan and proteoglycan link protein 1target
Hyaluronic acidHyaluronan and proteoglycan link protein 3target
Hyaluronic acidHyaluronan and proteoglycan link protein 4target
Hyaluronic acidHyaluronan-binding protein 2target
Hyaluronic acidLayilintarget
Hyaluronic acidStabilin-2target
Hyaluronic acidTumor necrosis factor-inducible gene 6 proteintarget
Hyaluronic acidInterphotoreceptor matrix proteoglycan 2target
Hyaluronic acidIntracellular hyaluronan-binding protein 4target
BendazacFree radicalstarget
BendazacProstaglandin G/H synthase 1target
BendazacProstaglandin G/H synthase 2target
EteplirsenDMD-001 gene (exon 51 target site)target
RomosozumabSclerostintarget
NusinersenExonucleaseenzyme
NusinersenSurvival motor neuron proteintarget
BurosumabFibroblast growth factor 23target