Antiviral Agents

Name
Antiviral Agents
Accession Number
DBCAT000066  (DBCAT001226, DBCAT003779)
Description

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.

ATC Classification
Drugs
DrugDrug Description
VidarabineAn antiviral agent used to treat various viral infections.
IdoxuridineA pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis.
DocosanolAn antiviral used to treat orofacial herpes sores.
FomivirsenIndicated for the local treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS), when other therapy has been ineffective or is considered unsuitable [FDA Label, L1428].
EdoxudineA deoxythymidine analog used to treat herpetic keratitis.
TrifluridineA nucleoside metabolic inhibitor used to treat keratoconjunctivitis and epithelial keratitis caused by simplex virus, and as a part of chemotherapy for certain types of metastatic gastrointestinal cancers.
AcyclovirA guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster.
SinecatechinsA topical agent used to treat external genital and perianal warts in immunocompetent adult patients.
Inosine pranobexA medication used to treat subacute sclerosing panencephalitis.
TromantadineTromantadine is marketed as Viru-Merz in the Czech Republic . It is an antiviral used in the treatment of herpes zoster and simplex.
GanciclovirA DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye.
Peginterferon alfa-2aA modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
Interferon alfa-n1A purified form of human interferon used to stimulate the innate antiviral response in the treatment of genital warts due to human papilloma virus.
Peginterferon alfa-2bA purified form of human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C, genital warts, and some cancers.
Interferon beta-1aA form of recombinant human interferon used to slow disease progression and reduce the frequency of clinical symptoms in patients who have relapsing multiple sclerosis.
Interferon alfacon-1A recombinant interferon similar the interferon alfa subtype which is used to treat hepatitis C infections.
EnfuvirtideAn HIV-1 gp41 fusion inhibitor used in patients experiencing HIV-1 replication who are already being treated with other anti-retrovirals.
PalivizumabA monoclonal anti respiratory syncytial virus F protein antibody used to prevent serious sequelae caused by respiratory syncytial virus infection in pediatric patients.
OseltamivirA neuraminidase inhibitor used in the prophylaxis and treatment of influenza.
NelfinavirA viral protease inhibitor used in the treatment of HIV infection.
IndinavirA protease inhibitor used to treat HIV infection.
NevirapineA non-nucleoside reverse transcriptase inhibitor used as part of a management regimen for HIV-1 virus infection.
PenciclovirA topical nucleoside polymerase inhibitor used in the treatment of recurrent herpes labialis.
Tenofovir disoproxilA nucleotide analog reverse transcriptase inhibitor used in the treatment of Hepatitis B infection and used in the management of HIV-1 infection.
CidofovirAn antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS.
FamciclovirA nucleoside analog DNA polymerase inhibitor used for the treatment of recurrent cold sores and genital herpes in healthy patients and patients with HIV, and to manage herpes zoster.
EntecavirA nucleoside analogue used in the treatment of chronic hepatitis B for patients with active viral replication, histological evidence of active disease, or persistent elevations in liver transaminases.
RimantadineAn RNA synthesis inhibitor used to prevent influenza A infection.
ZidovudineA dideoxynucleoside used in the treatment of HIV infection.
RitonavirAn HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.
FoscarnetAn antiviral used to treat CMV, HIV, and HSV infections.
ZanamivirA neuraminidase inhibitor used to treat influenza A and B.
ValaciclovirAn guanine nucleoside antiviral used to treat herpes exacerbations.
EfavirenzA non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV.
StavudineA dideoxynucleoside used in the treatment of HIV infection.
AmprenavirA protease inhibitor used to treat HIV infection.
DelavirdineA non-nucleoside reverse transcriptase inhibitor used to treat HIV infection.
LamivudineA reverse transcriptase inhibitor used to treat HIV and hepatitis B infections.
Adefovir dipivoxilA nucleotide analog used to treat chronic hepatitis B.
RibavirinA guanosine nucleoside used to treat some forms of Hepatitis C.
EmtricitabineA nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV.
DidanosineA reverse transcriptase inhibitor used to treat HIV.
AmantadineA medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications.
TipranavirA protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor.
ZalcitabineA dideoxynucleoside used to treat HIV.
AbacavirAn antiviral nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals for the treatment of HIV.
AtazanavirAn antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV.
SaquinavirAn HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.
DarunavirA HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.
TelbivudineA thymidine nucleoside analog used for the treatment of chronic hepatitis B with clinical evidence of viral replication or persistent elevations in serum aminotransferases (ALT or AST).
FosamprenavirAn antiretroviral agent used for the treatment and postexposure prophylaxis of human immunodeficiency virus (HIV-1) infection.
LopinavirAn HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection.
ValganciclovirAn antiviral medication used to treat cytomegalovirus (CMV) retinitis in patients diagnosed with acquired immunodeficiency syndrome (AIDS).
MaravirocA CCR5 co-receptor antagonist used with other antiretroviral medications to treat CCR5-tropic HIV-1 infection.
Calanolide AFor use in combination treatment of HIV infection (AIDS).
PleconarilInvestigated for use/treatment in upper respiratory infection.
Interferon alfaInvestigated for use/treatment in hepatitis (viral, C), leukemia (lymphoid), leukemia (myeloid), leukemia (unspecified), and melanoma.
LeronlimabA humanized monoclonal antibody being investigated
AlovudineInvestigated for use/treatment in HIV infection.
SimeprevirA direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4.
EtravirineA non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infections in combination with other antiretroviral agents.
PeramivirAn intravenous antiviral agent used to treat acute uncomplicated influenza in patients aged 2 years and older who are shown to be symptomatic for no more than two days.
ClevudineInvestigated for use/treatment in hepatitis (viral, B).
RaltegravirAn antiretroviral agent used for the treatment of HIV infections in conjunction with other antiretrovirals.
RilpivirineA non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1).
DolutegravirAn antiviral agent used for the treatment of HIV-1 infections in combination with other antiretroviral agents.
SofosbuvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
LedipasvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
OmbitasvirA direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
ParitaprevirA direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
Tenofovir alafenamideA nucleoside analog reverse transcriptase inhibitor used for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease.
CenicrivirocCenicriviroc has been used in trials studying the treatment of HIV-infection/AIDS, AIDS Dementia Complex, Nonalcoholic Steatohepatitis, Human Immunodeficiency Virus, and HIV-1-Associated Cognitive Motor Complex.
PritelivirPritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes.
SorivudineSorivudine has been used in trials studying the treatment of Chickenpox and HIV Infections.
VedroprevirVedroprevir has been investigated for the treatment of Hepatitis C, Chronic.
BeclabuvirBeclabuvir has been used in trials studying the treatment of Hepatitis C, Chronic.
AtevirdineAtevirdine has been used in trials studying the treatment of HIV Infections.
LobucavirLobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.
RacivirRacivir, also known as RCV, is an oxothiolane nucleoside reverse transcriptase inhibitor similar to emtricitabine and lamivudine. Racivir is a 50:50 mixture of emtricitabine DB00879 and its positive enantiomer. Racivir...
FiacitabineFiacitabine has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.
MoroxydineNot Annotated
MetisazoneNot Annotated
AdefovirNot Annotated
PodofiloxA topical agent used for the treatment of external genital warts and perianal warts.
IbacitabineNot Annotated
TenofovirTenofovir has been shown to be effective against HIV, herpes simplex virus-2, and hepatitis B virus. To know more about the specific product indications, please visit the information in the...
TecovirimatAn antiviral medication used to treat smallpox.
VesatolimodVesatolimod has been used in trials studying the treatment of Hepatitis B and Chronic Hepatitis B.
AsunaprevirAsunaprevir is indicated in combination with other agents for the treatment of chronic hepatitis C in adult patients with hepatitis C virus genotypes 1 or 4 and compensated liver cirrhosis....
TelaprevirAn NS3/4A viral protease inhibitor used in combination with other antivirals for the curative treatment of chronic Hepatitis C Virus infections.
MaribavirInvestigated for use/treatment in viral infection, transplantation (organ or tissue), cytomegalovirus (CMV) retinitis, and retinal disorders (unspecified).
BoceprevirA hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy.
ElvitegravirAn antiretroviral agent used in combination with other antiretrovirals for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults.
DaclatasvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
DasabuvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
FaldaprevirFaldaprevir has been investigated for the treatment of Chronic Hepatitis C.
UmifenovirA dual direct-acting antiviral/host-targeting agent used in the treatment and prophylaxis of influenza and other respiratory viruses.
LetermovirAn antiviral medication used to treat CMV infections and disease in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant (HSCT).
Baloxavir marboxilA polymerase acidic endonuclease inhibitor used to treat uncomplicated influenza.
Oseltamivir acidNot Available
BrivudineBrivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries.
EmivirineEmivirine has been used in trials studying the treatment of HIV Infections.
LapachoneLapachone has been used in trials studying the treatment of Cancer, Carcinoma, Advanced Solid Tumors, Head and Neck Neoplasms, and Carcinoma, Squamous Cell.
Betulinic AcidBetulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.
ElbasvirAn antiviral and NS5A inhibitor used to treat hepatitis C infections.
GrazoprevirAn antiviral and NS3/4A protease inhibitor used to treat hepatitis C infections.
VelpatasvirA NS5A inhibitor used to treat chronic hepatitis C infections in patients without cirrhosis or with compensated cirrhosis.
BictegravirAn integrase inhibitor used to treat HIV infections.
VoxilaprevirA nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections.
DoravirineA non-nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals to treat HIV-1 infections.
IbalizumabA CD4-specific antibody used to treat HIV infections.
PibrentasvirA Hepatitis C NS5A inhibitor used to treat Hepatitis C.
GlecaprevirA Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C.
PF-232798PF-232798 is under investigation in clinical trial NCT01140425 (Study To Evaluate The Effect Of A Multiple Oral Dose Of PF-00232798 On QT Intervals In Healthy Subjects).
Alovudine F-18Alovudine F-18 is under investigation in clinical trial NCT02819024 (Dexamethasone Effects in Patients With Refractory Non-Small Cell Lung Cancer Using FLT Positron Emission Tomography).
FialuridineFialuridine is under investigation in clinical trial NCT01337466 (Biodistribution and Dosimetry Evaluation of [124I]FIAU).
RupintrivirInvestigated for use/treatment in viral infection.
BMS-488043Investigated for use/treatment in HIV infection.
UC-781Investigated for use/treatment in HIV infection.
ElvucitabineInvestigated for use/treatment in hepatitis (viral, B) and HIV infection.
TaribavirinInvestigated for use/treatment in hepatitis (viral, C).
CapravirineInvestigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections and HIV infection.
DapivirineDapivirine has been investigated for the prevention of HIV-1 Infections and Topical Penile Exposures.
ArtesunateArtesunate is an artemesinin derivative indicated for the initial treatment of severe malaria.
RuzasvirRuzasvir has been used in trials studying the treatment of Hepatitis C, Hepatitis C, Chronic, and Hepatitis C Infection.
Laninamivir octanoateLaninamivir octanoate has been used in trials studying the treatment of Asthma.
IngavirinIngavirin has been used in trials studying the treatment of Influenza and Common Cold.
DexelvucitabineDexelvucitabine has been used in trials studying the treatment of HIV Infections and Human Immunodeficiency Virus.
LaninamivirLaninamivir has been used in trials studying the treatment of Influenza.
OdalasvirOdalasvir has been used in trials studying the treatment of Hepatitis C, Chronic and Chronic Hepatitis C Infection.
AdafosbuvirAdafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of AL-335).
BMS-955176BMS-955176 is under investigation in clinical trial NCT02415595 (Dose-finding Study of BMS-955176 to Treat HIV-1 Infected Treatment-naive Adults).
UprifosbuvirUprifosbuvir is under investigation in clinical trial NCT02332707 (Efficacy and Safety of Grazoprevir (MK-5172) and Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis C Genotype (GT)1 and...
RadavirsenRadavirsen is under investigation in clinical trial NCT01375985 (Safety Study of Single Administration Intravenous Treatment for Influenza).
JE-2147Not Available
N-hydroxyguanidineNot Available
5'-GuanylylmethylenebisphosphonateNot Available
JPC-3210JPC-3210 is a potent antimalarial agent. It is an erythrocytic schizonticide with potent in vitro antimalarial activity against multidrug-resistant Plasmodium falciparum lines, low cytotoxicity, potent in vivo efficacy against murine...
PirodavirPirodavir is an antipicornavirus agent.
R-82913Not Available
OpaviralineNot Available
L-756423Not Available
RemdesivirA nucleoside analog used to treat RNA virus infections including COVID-19.
TMC-310911TMC-310911 (also known as ASC-09) is a novel investigational protease inhibitor (PI) that is structurally similar to the currently available darunavir. It is being investigated for use in HIV-1 infections....
TriazavirinAn antiviral used to treat several strains of influenza.
ValomaciclovirInvestigated for use/treatment in herpes zoster infections and viral infection.
Valomaciclovir stearateValomaciclovir stearate is under investigation in clinical trial NCT00831103 (A Phase 2b Trial of EPB-348 for the Treatment of Herpes Zoster).
RavidasvirRavidasvir is under investigation in clinical trial NCT02961426 (Sofosbuvir Plus Ravidasvir for the Treatment of HCV Chronic Infection).
IslatravirIslatravir is under investigation in clinical trial NCT04233216 (Doravirine/islatravir (DOR/ISL) in Heavily Treatment-experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)).
BaloxavirBaloxavir is under investigation in clinical trial NCT04327791 (Combination Therapy With Baloxavir and Oseltamavir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)).
GS-441524An experimental nucleoside analog antiviral investigated for its use in the treatment of Ebola and SARS-CoV-2 infections.
Drugs & Drug Targets
DrugTargetType
VidarabineDNA polymerase catalytic subunittarget
VidarabineThymidine kinasetarget
VidarabineThymidine kinasetarget
VidarabineAdenosine deaminaseenzyme
IdoxuridineThymidine kinasetarget
IdoxuridineDNAtarget
DocosanolEnvelope glycoprotein GP350target
DocosanolEnvelope glycoprotein GP340target
Fomivirsen30 kDa immediate-early protein 2target
Fomivirsen45 kDa immediate-early protein 2target
EdoxudineSerum albumincarrier
EdoxudineDNA polymerasetarget
TrifluridineThymidylate synthasetarget
TrifluridineDNAtarget
TrifluridineThymidine kinase, cytosolicenzyme
TrifluridineThymidine phosphorylaseenzyme
TrifluridineSolute carrier family 22 member 6transporter
TrifluridineSodium/nucleoside cotransporter 1transporter
TrifluridineEquilibrative nucleoside transporter 1transporter
TrifluridineEquilibrative nucleoside transporter 2transporter
TrifluridineSerum albumincarrier
AcyclovirDNA polymerase catalytic subunittarget
AcyclovirDNA polymerase catalytic subunittarget
AcyclovirThymidine kinasetarget
AcyclovirSolute carrier family 22 member 1transporter
AcyclovirSolute carrier family 22 member 6transporter
AcyclovirSolute carrier family 22 member 8transporter
AcyclovirIleal sodium/bile acid cotransportertransporter
AcyclovirMultidrug and toxin extrusion protein 1transporter
AcyclovirMultidrug and toxin extrusion protein 2transporter
AcyclovirThymidine kinaseenzyme
AcyclovirGuanylate kinaseenzyme
AcyclovirNucleoside diphosphokinaseenzyme
AcyclovirPyruvate Kinasesenzyme
AcyclovirCreatine Kinasesenzyme
AcyclovirPhosphoglycerate Kinasesenzyme
AcyclovirSuccinyl-CoA Synthetasesenzyme
AcyclovirPhosphoenolpyruvate Carboxykinasesenzyme
AcyclovirAdenylosuccinate Synthetasesenzyme
AcyclovirSerum albumincarrier
GanciclovirDNA polymerase catalytic subunittarget
GanciclovirThymidine kinasetarget
GanciclovirSolute carrier family 22 member 1transporter
GanciclovirSolute carrier family 22 member 6transporter
GanciclovirSolute carrier family 22 member 8transporter
GanciclovirSolute carrier family 22 member 7transporter
GanciclovirDNAtarget
GanciclovirMultidrug and toxin extrusion protein 1transporter
GanciclovirMultidrug and toxin extrusion protein 2transporter
Peginterferon alfa-2aInterferon alpha/beta receptor 2target
Peginterferon alfa-2aInterferon alpha/beta receptor 1target
Peginterferon alfa-2aCytochrome P450 1A2enzyme
Interferon alfa-n1Interferon alpha/beta receptor 2target
Interferon alfa-n1Interferon alpha/beta receptor 1target
Interferon alfa-n1Cytochrome P450 1A2enzyme
Peginterferon alfa-2bInterferon alpha/beta receptor 1target
Peginterferon alfa-2bInterferon alpha/beta receptor 2target
Peginterferon alfa-2bCytochrome P450 1A2enzyme
Peginterferon alfa-2bCytochrome P450 2D6enzyme
Peginterferon alfa-2bCytochrome P450 2C9enzyme
Interferon beta-1aInterferon alpha/beta receptor 1target
Interferon beta-1aInterferon alpha/beta receptor 2target
Interferon beta-1aCytochrome P450 1A2enzyme
Interferon alfacon-1Interferon alpha/beta receptor 1target
Interferon alfacon-1Interferon alpha/beta receptor 2target
Interferon alfacon-1Cytochrome P450 1A2enzyme
EnfuvirtideEnvelope glycoproteintarget
EnfuvirtideCytochrome P450 2C19enzyme
EnfuvirtideCytochrome P450 2E1enzyme
PalivizumabFusion glycoprotein F0target
PalivizumabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
PalivizumabComplement C1r subcomponenttarget
PalivizumabComplement C1q subcomponent subunit Atarget
PalivizumabComplement C1q subcomponent subunit Btarget
PalivizumabComplement C1q subcomponent subunit Ctarget
PalivizumabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
PalivizumabHigh affinity immunoglobulin gamma Fc receptor Itarget
PalivizumabLow affinity immunoglobulin gamma Fc region receptor II-btarget
OseltamivirNeuraminidasetarget
OseltamivirSialidase-1target
OseltamivirSialidase-2target
OseltamivirMultidrug resistance-associated protein 4transporter
OseltamivirSolute carrier family 15 member 1transporter
OseltamivirSolute carrier family 22 member 8transporter
OseltamivirLiver carboxylesterase 1enzyme
NelfinavirHIV-1 proteasetarget
NelfinavirCytochrome P450 2C19enzyme
NelfinavirCytochrome P450 3A4enzyme
NelfinavirCytochrome P450 2B6enzyme
NelfinavirCytochrome P450 3A5enzyme
NelfinavirCytochrome P450 3A7enzyme
NelfinavirP-glycoprotein 1transporter
NelfinavirSolute carrier family 22 member 1transporter
NelfinavirSolute carrier organic anion transporter family member 1A2transporter
NelfinavirATP-binding cassette sub-family G member 2transporter
NelfinavirSolute carrier organic anion transporter family member 1B1transporter
NelfinavirCytochrome P450 2D6enzyme
NelfinavirSerum albumincarrier
NelfinavirUDP-glucuronosyltransferase 1-1enzyme
NelfinavirSolute carrier organic anion transporter family member 1B3transporter
NelfinavirSolute carrier organic anion transporter family member 2B1transporter
NelfinavirBile salt export pumptransporter
NelfinavirCytochrome P450 2C9enzyme
IndinavirHuman immunodeficiency virus type 1 proteasetarget
IndinavirCytochrome P450 3A4enzyme
IndinavirCytochrome P450 3A5enzyme
IndinavirCytochrome P450 3A7enzyme
IndinavirP-glycoprotein 1transporter
IndinavirSolute carrier family 22 member 1transporter
IndinavirMultidrug resistance-associated protein 1transporter
IndinavirSolute carrier organic anion transporter family member 1A2transporter
IndinavirSolute carrier organic anion transporter family member 1B1transporter
IndinavirCanalicular multispecific organic anion transporter 1transporter
IndinavirCytochrome P450 2D6enzyme
IndinavirUDP-glucuronosyltransferase 1-1enzyme
IndinavirSolute carrier organic anion transporter family member 2B1transporter
IndinavirBile salt export pumptransporter
NevirapineCytochrome P450 3A4enzyme
NevirapineCytochrome P450 2B6enzyme
NevirapineCytochrome P450 3A5enzyme
NevirapineCytochrome P450 2C9enzyme
NevirapineCytochrome P450 2A6enzyme
NevirapineCytochrome P450 2D6enzyme
NevirapineReverse transcriptase/RNaseHtarget
NevirapineSerum albumincarrier
NevirapineCytochrome P450 1A2enzyme
NevirapineSolute carrier family 22 member 1transporter
NevirapineCytochrome P450 3A7enzyme
PenciclovirDNA polymerase catalytic subunittarget
PenciclovirThymidine kinasetarget
Tenofovir disoproxilReverse transcriptase/RNaseHtarget
Tenofovir disoproxilSolute carrier family 22 member 6transporter
Tenofovir disoproxilSolute carrier family 22 member 8transporter
Tenofovir disoproxilMultidrug resistance-associated protein 7transporter
Tenofovir disoproxilMultidrug resistance-associated protein 4transporter
Tenofovir disoproxilCanalicular multispecific organic anion transporter 1transporter
Tenofovir disoproxilAdenylate kinase 2, mitochondrialenzyme
Tenofovir disoproxilAdenylate kinase 4, mitochondrialenzyme
Tenofovir disoproxilP-glycoprotein 1transporter
Tenofovir disoproxilNucleoside diphosphokinaseenzyme
Tenofovir disoproxilCreatine Kinasesenzyme
Tenofovir disoproxilDNA polymerase/reverse transcriptasetarget
CidofovirDNA polymerase catalytic subunittarget
CidofovirSolute carrier family 22 member 6transporter
CidofovirThymidine phosphorylaseenzyme
FamciclovirDNA polymerase catalytic subunittarget
FamciclovirAldehyde oxidaseenzyme
EntecavirDNAtarget
RimantadineMatrix protein 2target
ZidovudineSerum albumincarrier
ZidovudineCytochrome P450 2A6enzyme
ZidovudineCytochrome P450 2C9enzyme
ZidovudineCytochrome P450 3A4enzyme
ZidovudineReverse transcriptase/RNaseHtarget
ZidovudineSolute carrier family 22 member 2transporter
ZidovudineSolute carrier family 22 member 6transporter
ZidovudineSolute carrier family 22 member 7transporter
ZidovudineSolute carrier family 22 member 8transporter
ZidovudineSolute carrier family 22 member 11transporter
ZidovudineSodium/nucleoside cotransporter 1transporter
ZidovudineEquilibrative nucleoside transporter 2transporter
ZidovudineP-glycoprotein 1transporter
ZidovudineMultidrug resistance-associated protein 4transporter
ZidovudineMultidrug resistance-associated protein 5transporter
ZidovudineATP-binding cassette sub-family G member 2transporter
ZidovudineTelomerase reverse transcriptasetarget
ZidovudineThymidine kinase, cytosolicenzyme
ZidovudineUDP-glucuronosyltransferase 2B7enzyme
ZidovudineUDP-glucuronosyltransferase 1-1enzyme
RitonavirHuman immunodeficiency virus type 1 proteasetarget
RitonavirCytochrome P450 2D6enzyme
RitonavirCytochrome P450 2C9enzyme
RitonavirCytochrome P450 2C19enzyme
RitonavirCytochrome P450 2B6enzyme
RitonavirCytochrome P450 2C8enzyme
RitonavirP-glycoprotein 1transporter
RitonavirMultidrug resistance-associated protein 1transporter
RitonavirCanalicular multispecific organic anion transporter 1transporter
RitonavirSolute carrier organic anion transporter family member 1A2transporter
RitonavirATP-binding cassette sub-family G member 2transporter
RitonavirSolute carrier organic anion transporter family member 1B1transporter
RitonavirCytochrome P450 1A2enzyme
RitonavirNuclear receptor subfamily 1 group I member 2target
RitonavirSerum albumincarrier
RitonavirCytochrome P450 3A4enzyme
RitonavirCytochrome P450 3A5enzyme
RitonavirCytochrome P450 3A7enzyme
RitonavirUDP-glucuronosyltransferases (UGTs)enzyme
RitonavirSolute carrier organic anion transporter family member 2B1transporter
RitonavirBile salt export pumptransporter
RitonavirAlpha-1-acid glycoprotein 1carrier
RitonavirSolute carrier organic anion transporter family member 1B3transporter
FoscarnetDNA polymerase catalytic subunittarget
FoscarnetDNA polymerase catalytic subunittarget
FoscarnetSolute carrier family 22 member 6transporter
FoscarnetMonocarboxylate transporter 1transporter
ZanamivirNeuraminidasetarget
ZanamivirNeuraminidasetarget
ZanamivirSialidase-2target
ValaciclovirThymidine kinasetarget
ValaciclovirDNA polymerase catalytic subunittarget
ValaciclovirSolute carrier family 15 member 1transporter
ValaciclovirSolute carrier family 15 member 2transporter
ValaciclovirSolute carrier family 22 member 8transporter
ValaciclovirSolute carrier family 22 member 6transporter
ValaciclovirSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)transporter
ValaciclovirIleal sodium/bile acid cotransportertransporter
ValaciclovirGuanylate kinaseenzyme
ValaciclovirThymidine kinaseenzyme
EfavirenzCytochrome P450 2B6enzyme
EfavirenzCytochrome P450 3A4enzyme
EfavirenzCytochrome P450 2C19enzyme
EfavirenzCytochrome P450 2C9enzyme
EfavirenzCytochrome P450 1A2enzyme
EfavirenzCytochrome P450 2D6enzyme
EfavirenzReverse transcriptase/RNaseHtarget
EfavirenzCytochrome P450 2C8enzyme
EfavirenzSerum albumincarrier
EfavirenzCytochrome P450 3A5enzyme
EfavirenzCytochrome P450 3A7enzyme
EfavirenzUDP-glucuronosyltransferase 1-1enzyme
EfavirenzBile salt export pumptransporter
EfavirenzSolute carrier family 22 member 1transporter
StavudineSolute carrier family 22 member 6transporter
StavudineReverse transcriptase/RNaseHtarget
StavudineSodium/nucleoside cotransporter 1transporter
StavudineSerum albumincarrier
AmprenavirHuman immunodeficiency virus type 1 proteasetarget
AmprenavirCytochrome P450 3A4enzyme
AmprenavirP-glycoprotein 1transporter
AmprenavirMultidrug resistance-associated protein 1transporter
AmprenavirCytochrome P450 2B6enzyme
AmprenavirCytochrome P450 2C19enzyme
AmprenavirCytochrome P450 2C9enzyme
AmprenavirCytochrome P450 2D6enzyme
AmprenavirCytochrome P450 3A5enzyme
AmprenavirSolute carrier organic anion transporter family member 1B1transporter
DelavirdineCytochrome P450 3A4enzyme
DelavirdineCytochrome P450 2C9enzyme
DelavirdineCytochrome P450 2D6enzyme
DelavirdineCytochrome P450 3A5enzyme
DelavirdineCytochrome P450 3A7enzyme
DelavirdineCytochrome P450 2C19enzyme
DelavirdineReverse transcriptase/RNaseHtarget
LamivudineDNAtarget
LamivudineProtein Ptarget
LamivudineMultidrug resistance-associated protein 1transporter
LamivudineSolute carrier family 22 member 6transporter
LamivudineATP-binding cassette sub-family G member 2transporter
LamivudineReverse transcriptase/RNaseHtarget
LamivudineSolute carrier family 22 member 1transporter
LamivudineSolute carrier family 22 member 2transporter
LamivudineSolute carrier family 22 member 3transporter
LamivudineDeoxycytidine kinaseenzyme
LamivudineUMP-CMP kinaseenzyme
LamivudinePhosphoglycerate kinase 1enzyme
LamivudineNucleoside diphosphate kinase Aenzyme
LamivudineNucleoside diphosphate kinase Benzyme
LamivudineCholine-phosphate cytidylyltransferase Aenzyme
LamivudineEthanolamine-phosphate cytidylyltransferaseenzyme
LamivudineP-glycoprotein 1transporter
LamivudineMultidrug resistance-associated protein 4transporter
LamivudineCanalicular multispecific organic anion transporter 2transporter
LamivudineCanalicular multispecific organic anion transporter 1transporter
Lamivudine5'(3')-deoxyribonucleotidase, cytosolic typeenzyme
LamivudineSerum albumincarrier
Adefovir dipivoxilDNA polymerase/reverse transcriptasetarget
Adefovir dipivoxilSolute carrier family 22 member 6transporter
Adefovir dipivoxilMultidrug resistance-associated protein 4transporter
Adefovir dipivoxilMultidrug resistance-associated protein 5transporter
Adefovir dipivoxilSolute carrier family 22 member 3transporter
Adefovir dipivoxilAdenylate kinase 2, mitochondrialenzyme
Adefovir dipivoxilAdenylate kinase 4, mitochondrialenzyme
Adefovir dipivoxilNucleoside diphosphate kinase Aenzyme
Adefovir dipivoxilNucleoside diphosphate kinase Benzyme
RibavirinRNA-directed RNA polymerase Ltarget
RibavirinRNA-directed RNA polymerase catalytic subunittarget
RibavirinInosine-5'-monophosphate dehydrogenase 1target
RibavirinGenome polyproteintarget
RibavirinInosine-5'-monophosphate dehydrogenase 2target
RibavirinAdenosine kinaseenzyme
RibavirinEquilibrative nucleoside transporter 1transporter
RibavirinSolute carrier family 28 member 3transporter
RibavirinCytosolic purine 5'-nucleotidaseenzyme
EmtricitabineReverse transcriptase/RNaseHtarget
EmtricitabineDeoxycytidine kinaseenzyme
EmtricitabineSerum albumincarrier
EmtricitabineMultidrug and toxin extrusion protein 1transporter
DidanosineSolute carrier family 22 member 6transporter
DidanosinePurine nucleoside phosphorylasetarget
DidanosineReverse transcriptase/RNaseHtarget
DidanosineEquilibrative nucleoside transporter 1transporter
DidanosineEquilibrative nucleoside transporter 2transporter
DidanosineSerum albumincarrier
AmantadineDopamine D2 receptortarget
AmantadineMatrix protein 2target
AmantadineAromatic-L-amino-acid decarboxylaseenzyme
AmantadineAmine oxidase [flavin-containing] Benzyme
AmantadineSolute carrier family 22 member 2transporter
AmantadineSolute carrier family 22 member 1transporter
AmantadineGlutamate receptor ionotropic, NMDA 3Atarget
AmantadineNeuronal acetylcholine receptor subunit alpha-7target
AmantadineNeuronal acetylcholine receptor subunit alpha-4target
AmantadineNeuronal acetylcholine receptor subunit alpha-3target
TipranavirHuman immunodeficiency virus type 1 proteasetarget
TipranavirCytochrome P450 3A4enzyme
TipranavirCytochrome P450 2D6enzyme
TipranavirCytochrome P450 2C19enzyme
TipranavirBile salt export pumptransporter
TipranavirUDP-glucuronosyltransferase 1-1enzyme
TipranavirSolute carrier organic anion transporter family member 2B1transporter
TipranavirSolute carrier organic anion transporter family member 1B1transporter
TipranavirSolute carrier organic anion transporter family member 1B3transporter
TipranavirP-glycoprotein 1transporter
ZalcitabineDeoxycytidine kinaseenzyme
ZalcitabineSolute carrier family 22 member 6transporter
ZalcitabineSolute carrier family 22 member 7transporter
ZalcitabineReverse transcriptase/RNaseHtarget
ZalcitabineEquilibrative nucleoside transporter 1transporter
ZalcitabineEquilibrative nucleoside transporter 2transporter
ZalcitabineSerum albumincarrier
AbacavirAlcohol dehydrogenase 6enzyme
AbacavirUDP-glucuronosyltransferase 1-1enzyme
AbacavirReverse transcriptase/RNaseHtarget
AbacavirAdenosine kinaseenzyme
AbacavirHLA class I histocompatibility antigen, B-57 alpha chaintarget
AtazanavirHuman immunodeficiency virus type 1 proteasetarget
AtazanavirCytochrome P450 3A4enzyme
AtazanavirCytochrome P450 2C9enzyme
AtazanavirP-glycoprotein 1transporter
AtazanavirMultidrug resistance-associated protein 1transporter
AtazanavirSerum albumincarrier
AtazanavirUDP-glucuronosyltransferase 1-1enzyme
AtazanavirSolute carrier organic anion transporter family member 1B1transporter
AtazanavirSolute carrier organic anion transporter family member 1B3transporter
AtazanavirCytochrome P450 2C8enzyme
AtazanavirBile salt export pumptransporter
Atazanaviralpha1-acid glycoproteincarrier
AtazanavirCytochrome P450 1A2enzyme
AtazanavirSolute carrier organic anion transporter family member 2B1transporter
SaquinavirHuman immunodeficiency virus type 1 proteasetarget
SaquinavirCytochrome P450 3A4enzyme
SaquinavirCytochrome P450 3A5enzyme
SaquinavirAlpha-1-acid glycoprotein 1carrier
SaquinavirSerum albumincarrier
SaquinavirCytochrome P450 3A7enzyme
SaquinavirP-glycoprotein 1transporter
SaquinavirSolute carrier family 22 member 1transporter
SaquinavirSolute carrier organic anion transporter family member 1A2transporter
SaquinavirATP-binding cassette sub-family G member 2transporter
SaquinavirSolute carrier organic anion transporter family member 1B1transporter
SaquinavirMultidrug resistance-associated protein 1transporter
SaquinavirCanalicular multispecific organic anion transporter 1transporter
SaquinavirCytochrome P450 2C8enzyme
SaquinavirCytochrome P450 2D6enzyme
SaquinavirSolute carrier organic anion transporter family member 2B1transporter
SaquinavirBile salt export pumptransporter
DarunavirHuman immunodeficiency virus type 1 proteasetarget
DarunavirCytochrome P450 3A4enzyme
DarunavirSolute carrier organic anion transporter family member 1B1transporter
DarunavirP-glycoprotein 1transporter
DarunavirSerum albumincarrier
DarunavirAlpha-1-acid glycoprotein 1carrier
DarunavirCytochrome P450 2D6enzyme
TelbivudineProtein Ptarget
TelbivudineDNAtarget
FosamprenavirHuman immunodeficiency virus type 1 proteasetarget
FosamprenavirCytochrome P450 3A4enzyme
LopinavirHuman immunodeficiency virus type 1 proteasetarget
LopinavirCytochrome P450 3A4enzyme
LopinavirCytochrome P450 2D6enzyme
LopinavirCytochrome P450 2C19enzyme
LopinavirP-glycoprotein 1transporter
LopinavirCytochrome P450 2B6enzyme
LopinavirCytochrome P450 2C9enzyme
LopinavirCytochrome P450 3A Subfamilyenzyme
LopinavirSolute carrier organic anion transporter family member 1B1transporter
LopinavirSolute carrier organic anion transporter family member 1B3transporter
LopinavirBile salt export pumptransporter
LopinavirCytochrome P450 1A2enzyme
LopinavirAlpha-1-acid glycoprotein 1carrier
LopinavirSerum albumincarrier
ValganciclovirDNAtarget
ValganciclovirSolute carrier family 15 member 1transporter
ValganciclovirSolute carrier family 15 member 2transporter
ValganciclovirSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)transporter
MaravirocC-C chemokine receptor type 5target
MaravirocCytochrome P450 3A4enzyme
Calanolide AGag-Pol polyproteintarget
Calanolide ACytochrome P450 3A4enzyme
PleconarilPolyproteintarget
Interferon alfaInterferon alpha/beta receptor 1target
Interferon alfaCytochrome P450 1A2enzyme
LeronlimabC-C chemokine receptor type 5target
SimeprevirNS3 proteasetarget
SimeprevirSerum albumincarrier
SimeprevirCytochrome P450 1A2enzyme
SimeprevirP-glycoprotein 1transporter
SimeprevirSolute carrier organic anion transporter family member 1B1transporter
SimeprevirSolute carrier organic anion transporter family member 1B3transporter
SimeprevirCytochrome P450 3A4enzyme
SimeprevirCanalicular multispecific organic anion transporter 1transporter
SimeprevirATP-binding cassette sub-family G member 2transporter
SimeprevirSolute carrier organic anion transporter family member 2B1transporter
SimeprevirSodium/bile acid cotransportertransporter
SimeprevirBile salt export pumptransporter
EtravirineCytochrome P450 2C19enzyme
EtravirineCytochrome P450 2C9enzyme
EtravirineCytochrome P450 3A4enzyme
EtravirineGag-Pol polyproteintarget
EtravirineGag-Pol polyproteintarget
EtravirineP-glycoprotein 1transporter
EtravirineMultidrug resistance protein 3transporter
PeramivirNeuraminidasetarget
PeramivirNeuraminidasetarget
PeramivirNeuraminidasetarget
RaltegravirUDP-glucuronosyltransferase 1-1enzyme
RaltegravirIntegrasetarget
RilpivirineCytochrome P450 3A4enzyme
RilpivirineReverse transcriptase/RNaseHtarget
RilpivirineNuclear receptor subfamily 1 group I member 2target
RilpivirineCytochrome P450 2C19enzyme
RilpivirineCytochrome P450 2B6enzyme
RilpivirineP-glycoprotein 1transporter
RilpivirineATP-binding cassette sub-family G member 2transporter
RilpivirineSolute carrier organic anion transporter family member 1B1transporter
RilpivirineSolute carrier organic anion transporter family member 1B3transporter
RilpivirineSerum albumincarrier
RilpivirineCytochrome P450 2D6enzyme
DolutegravirUDP-glucuronosyltransferase 1-1enzyme
DolutegravirCytochrome P450 3A Subfamilyenzyme
DolutegravirIntegrasetarget
DolutegravirSolute carrier family 22 member 2transporter
DolutegravirUDP-glucuronosyltransferase 1-3enzyme
DolutegravirUDP-glucuronosyltransferase 1-9enzyme
DolutegravirATP-binding cassette sub-family G member 2transporter
DolutegravirSolute carrier family 22 member 6transporter
DolutegravirSolute carrier family 22 member 8transporter
DolutegravirP-glycoprotein 1transporter
SofosbuvirP-glycoprotein 1transporter
SofosbuvirATP-binding cassette sub-family G member 2transporter
SofosbuvirRNA-dependent RNA-polymerasetarget
SofosbuvirLysosomal protective proteinenzyme
SofosbuvirCarboxylesteraseenzyme
SofosbuvirHistidine triad nucleotide-binding protein 1enzyme
SofosbuvirUMP-CMP kinaseenzyme
SofosbuvirNucleoside diphosphate kinase Aenzyme
LedipasvirNonstructural protein 5Atarget
LedipasvirP-glycoprotein 1transporter
LedipasvirATP-binding cassette sub-family G member 2transporter
OmbitasvirNonstructural protein 5Atarget
OmbitasvirCytochrome P450 2C8enzyme
OmbitasvirP-glycoprotein 1transporter
OmbitasvirUDP-glucuronosyltransferase 1-4transporter
OmbitasvirATP-binding cassette sub-family G member 2transporter
ParitaprevirNS3/4A proteintarget
ParitaprevirCytochrome P450 3A4enzyme
ParitaprevirCytochrome P450 3A5enzyme
ParitaprevirATP-binding cassette sub-family G member 2transporter
ParitaprevirP-glycoprotein 1transporter
ParitaprevirSolute carrier organic anion transporter family member 1B1transporter
ParitaprevirSolute carrier organic anion transporter family member 1B3transporter
ParitaprevirUDP-glucuronosyltransferase 1-1enzyme
Tenofovir alafenamideReverse transcriptase/RNaseHtarget
Tenofovir alafenamideP-glycoprotein 1transporter
Tenofovir alafenamideMultidrug resistance-associated protein 4transporter
Tenofovir alafenamideSolute carrier family 22 member 6transporter
Tenofovir alafenamideSolute carrier family 22 member 8transporter
Tenofovir alafenamideLysosomal protective proteinenzyme
Tenofovir alafenamideLiver carboxylesterase 1enzyme
Tenofovir alafenamideATP-binding cassette sub-family G member 2transporter
Tenofovir alafenamideSolute carrier organic anion transporter family member 1B1transporter
Tenofovir alafenamideSolute carrier organic anion transporter family member 1B3transporter
Tenofovir alafenamideReverse transcriptasetarget
Tenofovir alafenamideDNA polymerasetarget
Tenofovir alafenamideSerum albumincarrier
Tenofovir alafenamideCytochrome P450 3A4enzyme
Tenofovir alafenamideAdenylate kinase isoenzyme 1enzyme
Tenofovir alafenamideAdenylate kinase 2, mitochondrialenzyme
Tenofovir alafenamideNucleoside diphosphate kinase Aenzyme
Tenofovir alafenamideNucleoside diphosphate kinase Benzyme
AdefovirDNA polymerase/reverse transcriptasetarget
PodofiloxDNA topoisomerase 2-alphatarget
PodofiloxTubulin alpha-4A chaintarget
PodofiloxTubulin beta chaintarget
TenofovirP-glycoprotein 1transporter
TenofovirSolute carrier family 22 member 6transporter
TenofovirSolute carrier family 22 member 8transporter
TenofovirMultidrug resistance-associated protein 4transporter
TenofovirCytochrome P450 3A4enzyme
TenofovirNucleoside diphosphate kinase Aenzyme
TenofovirNucleoside diphosphate kinase Benzyme
TenofovirAdenylate kinase isoenzyme 1enzyme
TenofovirAdenylate kinase 2, mitochondrialenzyme
TenofovirReverse transcriptase/RNaseHtarget
TenofovirReverse transcriptasetarget
TenofovirDNA polymerasetarget
TenofovirSerum albumincarrier
TecovirimatEnvelope protein F13target
TecovirimatUDP-glucuronosyltransferase 1-1enzyme
TecovirimatUDP-glucuronosyltransferase 1-4enzyme
AsunaprevirGenome polyproteintarget
AsunaprevirCytochrome P450 3A4enzyme
AsunaprevirCytochrome P450 3A5enzyme
AsunaprevirCytochrome P450 2A6enzyme
AsunaprevirCytochrome P450 2B6enzyme
AsunaprevirCytochrome P450 2C9enzyme
AsunaprevirCytochrome P450 2C19enzyme
AsunaprevirCytochrome P450 2D6enzyme
AsunaprevirSolute carrier organic anion transporter family member 1B1transporter
AsunaprevirSolute carrier organic anion transporter family member 1B3transporter
AsunaprevirSolute carrier organic anion transporter family member 2B1transporter
AsunaprevirP-glycoprotein 1transporter
TelaprevirCytochrome P450 3A4enzyme
TelaprevirNS3/4A proteintarget
TelaprevirP-glycoprotein 1transporter
TelaprevirSerum albumincarrier
TelaprevirAlpha-1-acid glycoprotein 1carrier
TelaprevirSolute carrier organic anion transporter family member 1B1target
TelaprevirSolute carrier organic anion transporter family member 2B1target
MaribavirSerine/threonine protein kinase UL97target
MaribavirSerine/threonine protein kinase UL97target
BoceprevirCytochrome P450 3A4enzyme
BoceprevirCytochrome P450 3A5enzyme
BoceprevirP-glycoprotein 1transporter
BoceprevirNS3/4A proteintarget
ElvitegravirIntegrasetarget
ElvitegravirCytochrome P450 3A4enzyme
ElvitegravirUDP-glucuronosyltransferase 1-4enzyme
DaclatasvirNonstructural protein 5Atarget
DaclatasvirCytochrome P450 3A5enzyme
DaclatasvirCytochrome P450 3A4enzyme
DaclatasvirCytochrome P450 3A43enzyme
DaclatasvirCytochrome P450 3A7enzyme
DaclatasvirP-glycoprotein 1transporter
DaclatasvirSolute carrier organic anion transporter family member 1B1transporter
DaclatasvirSolute carrier organic anion transporter family member 1B3transporter
DaclatasvirATP-binding cassette sub-family G member 2transporter
DasabuvirNonstructural protein 5B (NS5B)target
DasabuvirCytochrome P450 2C8enzyme
DasabuvirCytochrome P450 3A4enzyme
DasabuvirCytochrome P450 2D6enzyme
DasabuvirUDP-glucuronosyltransferase 1-4enzyme
DasabuvirATP-binding cassette sub-family G member 2transporter
DasabuvirATP-binding cassette sub-family B member 5transporter
DasabuvirP-glycoprotein 1transporter
UmifenovirUDP-glucuronosyltransferase 1-9enzyme
UmifenovirUDP-glucuronosyltransferase 2B7enzyme
UmifenovirCytochrome P450 3A4enzyme
UmifenovirCytochrome P450 2E1enzyme
UmifenovirCytochrome P450 1A2enzyme
UmifenovirCytochrome P450 2D6enzyme
UmifenovirCytochrome P450 2C9enzyme
UmifenovirCytochrome P450 3A5enzyme
UmifenovirDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
UmifenovirDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
LetermovirUDP-glucuronosyltransferase 1-1enzyme
LetermovirUDP-glucuronosyltransferase 1-3enzyme
LetermovirSolute carrier organic anion transporter family member 1B1transporter
LetermovirSolute carrier organic anion transporter family member 1B3transporter
LetermovirTripartite terminase subunit 1target
LetermovirTripartite terminase subunit 2target
LetermovirTripartite terminase subunit 3target
LetermovirCytochrome P450 2D6enzyme
LetermovirCytochrome P450 2C8enzyme
LetermovirCytochrome P450 2C19enzyme
LetermovirCytochrome P450 2C9enzyme
LetermovirCytochrome P450 2B6enzyme
LetermovirP-glycoprotein 1transporter
LetermovirATP-binding cassette sub-family G member 2transporter
LetermovirBile salt export pumptransporter
LetermovirSolute carrier family 22 member 8transporter
LetermovirCanalicular multispecific organic anion transporter 1transporter
LetermovirCytochrome P450 3A4enzyme
LetermovirCytochrome P450 3A5enzyme
LetermovirCytochrome P450 3A7enzyme
LetermovirCytochrome P450 3A43enzyme
Baloxavir marboxilATP-binding cassette sub-family B member 5transporter
Baloxavir marboxilUDP-glucuronosyltransferase 1-3enzyme
Baloxavir marboxilCytochrome P450 3A4enzyme
Baloxavir marboxilPolymerase acidic proteintarget
Oseltamivir acidNeuraminidasetarget
BrivudineThymidine kinase 2, mitochondrialtarget
BrivudineDNA polymerasetarget
BrivudineThymidine kinasetarget
EmivirineGag-Pol polyproteintarget
LapachoneRetinol-binding protein 3target
ElbasvirNonstructural protein 5Atarget
ElbasvirP-glycoprotein 1transporter
ElbasvirCytochrome P450 3A4enzyme
ElbasvirCytochrome P450 3A5enzyme
ElbasvirCytochrome P450 3A7enzyme
ElbasvirCytochrome P450 3A43enzyme
GrazoprevirP-glycoprotein 1transporter
GrazoprevirSolute carrier organic anion transporter family member 1B1transporter
GrazoprevirSolute carrier organic anion transporter family member 1B3transporter
GrazoprevirCytochrome P450 3A4enzyme
GrazoprevirNS3/4A proteintarget
GrazoprevirSerum albumincarrier
GrazoprevirAlpha-1-acid glycoprotein 1carrier
VelpatasvirCytochrome P450 2B6enzyme
VelpatasvirCytochrome P450 2C8enzyme
VelpatasvirCytochrome P450 3A4enzyme
VelpatasvirNonstructural protein 5Atarget
VelpatasvirP-glycoprotein 1transporter
VelpatasvirATP-binding cassette sub-family G member 2transporter
VelpatasvirSolute carrier organic anion transporter family member 1B1transporter
VelpatasvirSolute carrier organic anion transporter family member 1B3transporter
VelpatasvirSolute carrier organic anion transporter family member 2B1transporter
BictegravirReverse transcriptase/RNaseHtarget
BictegravirIntegrasetarget
BictegravirCytochrome P450 3A4enzyme
BictegravirUDP-glucuronosyltransferase 1-1enzyme
BictegravirPOU domain, class 2, transcription factor 2enzyme
BictegravirMultidrug and toxin extrusion protein 1enzyme
VoxilaprevirCytochrome P450 3A4enzyme
VoxilaprevirCytochrome P450 1A2enzyme
VoxilaprevirCytochrome P450 2C8enzyme
VoxilaprevirNS3/4A proteintarget
VoxilaprevirP-glycoprotein 1transporter
VoxilaprevirATP-binding cassette sub-family G member 2transporter
VoxilaprevirSolute carrier organic anion transporter family member 1B1transporter
VoxilaprevirSolute carrier organic anion transporter family member 1B3transporter
DoravirineCytochrome P450 3A4enzyme
DoravirineCytochrome P450 3A5enzyme
DoravirineReverse transcriptase/RNaseHtarget
IbalizumabT-cell surface glycoprotein CD4target
IbalizumabC-C chemokine receptor type 5target
IbalizumabC-X-C chemokine receptor type 4target
PibrentasvirNonstructural protein 5Atarget
PibrentasvirCytochrome P450 3A Subfamilyenzyme
PibrentasvirUDP-glucuronosyltransferase 1-1enzyme
PibrentasvirP-glycoprotein 1transporter
PibrentasvirATP-binding cassette sub-family G member 2transporter
PibrentasvirSolute carrier organic anion transporter family member 1B1transporter
PibrentasvirSolute carrier organic anion transporter family member 1B3transporter
GlecaprevirCytochrome P450 3A Subfamilyenzyme
GlecaprevirUDP-glucuronosyltransferase 1-1enzyme
GlecaprevirP-glycoprotein 1transporter
GlecaprevirATP-binding cassette sub-family G member 2transporter
GlecaprevirSolute carrier organic anion transporter family member 1B1transporter
GlecaprevirSolute carrier organic anion transporter family member 1B3transporter
GlecaprevirNS3 proteasetarget
GlecaprevirCytochrome P450 3A4enzyme
RupintrivirGenome polyproteintarget
BMS-488043Free fatty acid receptor 4target
UC-781Gag-Pol polyproteintarget
TaribavirinDNAtarget
TaribavirinRNA-directed RNA polymerase Ltarget
TaribavirinEctonucleotide pyrophosphatase/phosphodiesterase family member 1target
TaribavirinRNA-directed RNA polymerase catalytic subunittarget
TaribavirinCytosolic purine 5'-nucleotidasetarget
TaribavirinInosine-5'-monophosphate dehydrogenase 1target
CapravirineCytochrome P450 3A4enzyme
CapravirineGag-Pol polyproteintarget
CapravirineCytochrome P450 2C8enzyme
CapravirineCytochrome P450 2C9enzyme
CapravirineCytochrome P450 2C19enzyme
DapivirineGag-Pol polyproteintarget
ArtesunateMalaria protein EXP-1target
ArtesunateCytochrome P450 2A6enzyme
ArtesunateUDP-glucuronosyltransferase 2B7enzyme
ArtesunateUDP-glucuronosyltransferase 1-9enzyme
ArtesunateATP-binding cassette sub-family G member 2transporter
ArtesunateP-glycoprotein 1transporter
ArtesunateSolute carrier organic anion transporter family member 1B1transporter
ArtesunateSolute carrier family 22 member 8transporter
ArtesunateSerum albumincarrier
JE-2147Gag-Pol polyproteintarget
5'-GuanylylmethylenebisphosphonatePhosphoenolpyruvate carboxykinase, cytosolic [GTP]target
PirodavirGenome polyproteintarget
PirodavirGenome polyproteintarget
R-82913Gag-Pol polyproteintarget
R-82913Gag-Pol polyproteintarget
OpaviralineGag-Pol polyproteintarget
L-756423Gag-Pol polyproteintarget
RemdesivirReplicase polyprotein 1abtarget
RemdesivirRNA-directed RNA polymerase Ltarget
RemdesivirCytochrome P450 2C8enzyme
RemdesivirCytochrome P450 2D6enzyme
RemdesivirCytochrome P450 3A4enzyme
RemdesivirSolute carrier organic anion transporter family member 1B1transporter
RemdesivirP-glycoprotein 1transporter
RemdesivirSolute carrier organic anion transporter family member 1B3transporter
RemdesivirBile salt export pumptransporter
RemdesivirMultidrug resistance-associated protein 4transporter
RemdesivirSodium/bile acid cotransportertransporter
TMC-310911HIV-1 proteasetarget
GS-441524Replicase polyprotein 1abtarget
GS-441524RNA-directed RNA polymerase Ltarget