Blood Substitutes and Perfusion Solutions

DrugDrug NameDrug Description
DB00123L-LysineAn amino acid commonly found as a component of total parenteral nutrition.
DB00125ArginineAn amino acid commonly found as a component of total parenteral nutrition.
DB00145GlycineAn amino acid commonly used as a component of total parenteral nutrition and is also used as irrigation during surgery.
DB00653Magnesium sulfateA drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany.
DB01390Sodium bicarbonateA compound used for the symptomatic treatment of heartburn, acid indigestion, and upset stomach as well as the treatment of metabolic acidosis associated with conditions such as severe renal disease and circulatory insufficiency due to shock.
DB01638SorbitolA product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener.
DB03754TromethamineA proton acceptor used for the prevention and correction of metabolic acidosis associated with various clinical conditions, such as cardiac bypass surgery.
DB06767Ammonium chlorideExpectorant in cough syrups. The ammonium ion (NH4+) in the body plays an important role in the maintenance of acid-base balance. The kidney uses ammonium (NH4+) in place of sodium...
DB09106Hydroxyethyl StarchA plasma volume substitute used to treat and prevent hypovolemia.
DB09153Sodium chlorideAn ingredient found in a variety of nutritional products as a source of electrolytes and water.
DB09154Sodium citrateAn ingredient used for the anticoagulation of whole blood as part of automated apheresis procedures.
DB09255DextranA low molecular weight dextran used as an adjunctive treatment of shock or impending shock due to hemorrhage, burns, surgery or other trauma, as well as the prophylaxis of venous thrombosis and pulmonary embolism during high-risk medical procedures.
DB09393Amino acidsMixture of amino acids ; used for parenteral nutrition in infants.
DB09395Sodium acetateA compound used for electrolyte replenishment and total parenteral nutrition (TPN) therapy.
DB09407Magnesium chlorideAn ionic compound and source of magnesium used for electrolyte replenishment and conditions associated with magnesium deficiencies.
DB09483Potassium lactateNot Annotated
DB09561Sodium glycerophosphateA medication used to treat hypophosphatemia.
DB11876Alanyl glutamineAlanyl Glutamine is under investigation in clinical trial NCT00338221 (Clinical Trial of Alanyl-Glutamine or Glycine in Children With Persistent Diarrhea or Malnutrition).
DB12473TaurolidineTaurolidine has been investigated for the prevention of Central Venous Catheter, Home Parenteral Nutrition, and Catheter-Related Infections.
DB13218Mandelic acidMandelic acid is an approved aromatic, alpha hydroxy acid . Mandelic acid is used as an ingredient in cosmetics and drug products applied topically.
DB13658Hemoglobin raffimerNot Annotated
DB13838NoxytiolinLocal antibacterial that probably acts by releasing formaldehyde in aqueous solutions. It is used for THERAPEUTIC IRRIGATION of infected body cavities - bladder, peritoneum, etc. and as a spray for...
DB13862Magnesium phosphateNot Annotated
DB13864Hemoglobin crosfumarilHemoglobin in which the alpha-subunit are cross-linked intramolecularly.
DB00336NitrofuralFor the treatment of bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms.
DB00576SulfamethizoleA sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections.
DB00742MannitolA sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, and to measure glomerular filtration rate.
DB00761Potassium chlorideA potassium salt used to treat hypokalemia.
DB00994NeomycinAn aminoglycoside used to treat a wide variety of infections in the body.
DB01164Calcium chlorideAn ionic compound used for the treatment of hypocalcemia and hyperkalemia, and as an antidote to magnesium intoxication due to overdosage of magnesium sulfate.
DB11073CetylpyridiniumA compound used to reduce plaque and gingivitis, as well as whiten teeth.
DB11110Magnesium citrateA laxative used in bowel preparation for colonoscopy or as a magnesium supplement.
DB13366Hydrochloric acidNot Annotated
DB14498Potassium acetateA medication used to treat hypokalemia.
DB14533Zinc chlorideA medication used to treat zinc deficiencies and associated symptoms and also in total parenteral nutrition.
DB03904UreaA keratolytic emollient used to treat hyperkeratotic lesions and moisturize the skin.
DrugDrug NameTargetType
DB00123L-LysineHigh affinity cationic amino acid transporter 1target
DB00123L-LysineCationic amino acid transporter 4target
DB00123L-LysineCationic amino acid transporter 3target
DB00123L-LysineLow affinity cationic amino acid transporter 2target
DB00123L-LysineLysine--tRNA ligasetarget
DB00123L-LysineMonocarboxylate transporter 10transporter
DB00123L-LysineSolute carrier family 22 member 4transporter
DB00125ArginineCationic amino acid transporter 3target
DB00125ArginineArginine decarboxylasetarget
DB00125ArginineArgininosuccinate lyasetarget
DB00125ArginineNitric oxide synthase, inducibletarget
DB00125ArginineHigh affinity cationic amino acid transporter 1target
DB00125ArginineArginase-2, mitochondrialtarget
DB00125ArginineCationic amino acid transporter 4target
DB00125ArginineArgininosuccinate synthasetarget
DB00125ArginineNitric oxide synthase, endothelialtarget
DB00125ArginineSolute carrier family 22 member 5transporter
DB00125ArginineMonocarboxylate transporter 10transporter
DB00125ArginineSolute carrier family 22 member 4transporter
DB00145GlycineGlutathione synthetasetarget
DB00145GlycineGlycine receptor subunit alpha-1target
DB00145GlycineSerine--pyruvate aminotransferasetarget
DB00145GlycineGlycine receptor subunit betatarget
DB00145GlycineSerine hydroxymethyltransferase, cytosolictarget
DB00145GlycineGlycine receptor subunit alpha-3target
DB00145GlycineGlycine receptor subunit alpha-2target
DB00145GlycineGlycine N-methyltransferasetarget
DB00145GlycineGlycine amidinotransferase, mitochondrialtarget
DB00145GlycineGlutamate receptor ionotropic, NMDA 3Btarget
DB00145GlycineGlycine dehydrogenase [decarboxylating], mitochondrialtarget
DB00145GlycineSodium- and chloride-dependent glycine transporter 1target
DB00145Glycine2-amino-3-ketobutyrate coenzyme A ligase, mitochondrialtarget
DB00145Glycine5-aminolevulinate synthase, nonspecific, mitochondrialtarget
DB00145Glycine5-aminolevulinate synthase, erythroid-specific, mitochondrialtarget
DB00145GlycineGlycine cleavage system H protein, mitochondrialtarget
DB00145GlycineGlycine--tRNA ligasetarget
DB00145GlycineGlutamate receptor ionotropic, NMDA 2Atarget
DB00145GlycineBile acid-CoA:amino acid N-acyltransferasetarget
DB00145GlycineN-arachidonyl glycine receptortarget
DB00145GlycineGlutamate receptor ionotropic, NMDA 2Ctarget
DB00145GlycineSerine hydroxymethyltransferasetarget
DB00145GlycineGlycine N-acyltransferasetarget
DB00145GlycineProton-coupled amino acid transporter 1target
DB00145GlycineSerine hydroxymethyltransferase, mitochondrialtarget
DB00145GlycineGlycine N-acyltransferase-like protein 2target
DB00145GlycineGlycine N-acyltransferase-like protein 1target
DB00145GlycineAlanine--glyoxylate aminotransferase 2, mitochondrialtarget
DB00145GlycineVesicular inhibitory amino acid transportertarget
DB00145GlycinePeroxisomal sarcosine oxidasetarget
DB00145GlycineSodium- and chloride-dependent glycine transporter 2target
DB00145GlycineMonocarboxylate transporter 10transporter
DB00653Magnesium sulfateVoltage-dependent calcium channel gamma-1 subunittarget
DB00653Magnesium sulfateVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit beta-1target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit beta-2target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01390Sodium bicarbonateElectrogenic sodium bicarbonate cotransporter 1transporter
DB01390Sodium bicarbonateSodium bicarbonate cotransporter 3transporter
DB01390Sodium bicarbonateElectroneutral sodium bicarbonate exchanger 1transporter
DB01390Sodium bicarbonateElectrogenic sodium bicarbonate cotransporter 4transporter
DB01390Sodium bicarbonateHydrogen ionstarget
DB01390Sodium bicarbonateSodium-driven chloride bicarbonate exchangertransporter
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolMalate synthase Gtarget
DB03754TromethamineCholera enterotoxin subunit Btarget
DB03754TromethamineS-adenosylmethionine decarboxylase proenzymetarget
DB03754TromethamineBiotin synthasetarget
DB03754TromethamineVascular endothelial growth factor Atarget
DB03754Tromethamine6-phosphogluconolactonasetarget
DB03754TromethamineDecorintarget
DB03754TromethamineAutolysintarget
DB03754TromethamineCytochrome c4target
DB03754TromethamineSoluble calcium-activated nucleotidase 1target
DB03754TromethamineLipoprotein NlpItarget
DB03754TromethamineDNA protection during starvation proteintarget
DB03754TromethaminePutative glucose-6-phosphate 1-epimerasetarget
DB03754TromethamineEndonuclease 8-like 1target
DB09154Sodium citrateMitochondrial 2-oxodicarboxylate carriertransporter
DB09154Sodium citrateSolute carrier family 13 member 2transporter
DB09154Sodium citrateSolute carrier family 13 member 5transporter
DB09154Sodium citrateTricarboxylate transport protein, mitochondrialtransporter
DB09395Sodium acetateAcetyl-coenzyme A synthetase, cytoplasmicenzyme
DB00336NitrofuralPyruvate dehydrogenase [ubiquinone]target
DB00336NitrofuralGlutathione reductasetarget
DB00336NitrofuralMalate dehydrogenasetarget
DB00336Nitrofural[Citrate [pro-3S]-lyase] ligasetarget
DB00336NitrofuralXanthine dehydrogenase/oxidaseenzyme
DB00576SulfamethizoleDihydropteroate synthasetarget
DB00576SulfamethizoleSerum albumincarrier
DB00576SulfamethizoleCytochrome P450 2C9enzyme
DB00742MannitolP-glycoprotein 1transporter
DB00742MannitolMannitol dehydrogenaseenzyme
DB00761Potassium chlorideSolute carrier family 12 member 2target
DB00761Potassium chlorideSolute carrier family 12 member 1target
DB00761Potassium chlorideSolute carrier family 12 member 5target
DB00761Potassium chlorideSolute carrier family 12 member 6target
DB00761Potassium chlorideSolute carrier family 12 member 7target
DB00761Potassium chlorideSolute carrier family 12 member 4target
DB00761Potassium chlorideSolute carrier family 12 member 2transporter
DB00761Potassium chlorideSolute carrier family 12 member 1transporter
DB00761Potassium chlorideSolute carrier family 12 member 5transporter
DB00761Potassium chlorideSolute carrier family 12 member 6transporter
DB00761Potassium chlorideSolute carrier family 12 member 7transporter
DB00761Potassium chlorideSolute carrier family 12 member 4transporter
DB00994Neomycin30S ribosomal protein S12target
DB00994Neomycin16S ribosomal RNAtarget
DB00994NeomycinExtracellular calcium-sensing receptortarget
DB01164Calcium chlorideProtein S100-A13target
DB14498Potassium acetateSodium/potassium-transporting ATPase subunit alpha-1target
DB14533Zinc chlorideB1 bradykinin receptortarget
DB14533Zinc chlorideMethylated-DNA--protein-cysteine methyltransferasetarget
DB14533Zinc chlorideFructose-bisphosphate aldolase Atarget
DB14533Zinc chlorideElongation factor 1-alpha 1target
DB14533Zinc chlorideAlpha-enolasetarget
DB14533Zinc chlorideGlyceraldehyde-3-phosphate dehydrogenase, testis-specifictarget
DB14533Zinc chlorideNucleoside diphosphate kinase Atarget
DB14533Zinc chlorideProtein disulfide-isomerasetarget
DB14533Zinc chlorideProtein disulfide-isomerase A3target
DB14533Zinc chloridePeroxiredoxin-1target
DB14533Zinc chloridePhosphoserine phosphatasetarget
DB14533Zinc chlorideTriosephosphate isomerasetarget
DB14533Zinc chlorideElongation factor Tu, mitochondrialtarget
DB14533Zinc chlorideEstrogen receptor alphatarget
DB14533Zinc chlorideInterleukin-3target
DB14533Zinc chlorideMetallothionein-2target
DB14533Zinc chlorideCopper chaperone for superoxide dismutasetarget
DB14533Zinc chlorideHistone deacetylase 1target
DB14533Zinc chlorideHistone deacetylase 4target
DB14533Zinc chlorideDNA-3-methyladenine glycosylasetarget
DB14533Zinc chlorideSemenogelin-1target
DB14533Zinc chlorideSuperoxide dismutase [Cu-Zn]target
DB14533Zinc chlorideHistone deacetylase 8target
DB14533Zinc chlorideApoptosis regulatory protein Sivatarget
DB14533Zinc chlorideGlycine receptor subunit alpha-1target
DB14533Zinc chlorideE3 ubiquitin-protein ligase Mdm2target
DB14533Zinc chlorideInsulintarget
DB14533Zinc chlorideUtrophintarget
DB14533Zinc chlorideAspartoacylasetarget
DB14533Zinc chlorideProtein S100-A8target
DB14533Zinc chlorideProtein S100-A9target
DB14533Zinc chlorideMatrix metalloproteinase-9target
DB14533Zinc chlorideTumor protein p73target
DB14533Zinc chlorideProtein S100-A2target
DB14533Zinc chlorideCellular tumor antigen p53target
DB14533Zinc chlorideMetallothionein-3target
DB14533Zinc chlorideProgrammed cell death protein 6target
DB14533Zinc chlorideDAN domain family member 5target
DB14533Zinc chlorideMetallothionein-1Atarget
DB14533Zinc chlorideAlpha-1B-glycoproteintarget
DB14533Zinc chlorideAlpha-2-macroglobulintarget
DB14533Zinc chlorideAngiotensinogentarget
DB14533Zinc chlorideAlpha-2-HS-glycoproteintarget
DB14533Zinc chlorideSerum amyloid P-componenttarget
DB14533Zinc chlorideApolipoprotein A-Itarget
DB14533Zinc chlorideApolipoprotein A-IItarget
DB14533Zinc chlorideApolipoprotein A-IVtarget
DB14533Zinc chlorideApolipoprotein B receptortarget
DB14533Zinc chlorideApolipoprotein Etarget
DB14533Zinc chlorideApolipoprotein L1target
DB14533Zinc chlorideComplement C1q subcomponent subunit Btarget
DB14533Zinc chlorideComplement C1q subcomponent subunit Ctarget
DB14533Zinc chlorideComplement C1r subcomponenttarget
DB14533Zinc chlorideComplement C1s subcomponenttarget
DB14533Zinc chlorideComplement C3target
DB14533Zinc chlorideComplement C4-Btarget
DB14533Zinc chlorideC4b-binding protein alpha chaintarget
DB14533Zinc chlorideC4b-binding protein beta chaintarget
DB14533Zinc chlorideComplement C5target
DB14533Zinc chlorideLys-63-specific deubiquitinase BRCC36target
DB14533Zinc chlorideComplement component C8 alpha chaintarget
DB14533Zinc chlorideComplement component C8 beta chaintarget
DB14533Zinc chlorideComplement component C8 gamma chaintarget
DB14533Zinc chlorideComplement factor Btarget
DB14533Zinc chlorideComplement factor Htarget
DB14533Zinc chlorideComplement factor Itarget
DB14533Zinc chlorideClusterintarget
DB14533Zinc chlorideCeruloplasmintarget
DB14533Zinc chlorideCarboxypeptidase N catalytic chaintarget
DB14533Zinc chlorideCarboxypeptidase N subunit 2target
DB14533Zinc chlorideDermcidintarget
DB14533Zinc chlorideDesmoplakintarget
DB14533Zinc chlorideCoagulation factor XIItarget
DB14533Zinc chlorideCoagulation factor XIII B chaintarget
DB14533Zinc chlorideProthrombintarget
DB14533Zinc chlorideFicolin-3target
DB14533Zinc chlorideFibrinogen alpha chaintarget
DB14533Zinc chlorideFibronectintarget
DB14533Zinc chlorideGelsolintarget
DB14533Zinc chlorideHemoglobin subunit alphatarget
DB14533Zinc chlorideHemoglobin subunit betatarget
DB14533Zinc chlorideHaptoglobin-related proteintarget
DB14533Zinc chlorideHornerintarget
DB14533Zinc chlorideInsulin-like growth factor-binding protein complex acid labile subunittarget
DB14533Zinc chlorideIg alpha-1 chain C regiontarget
DB14533Zinc chlorideIg mu chain C regiontarget
DB14533Zinc chlorideImmunoglobulin kappa variable 1-17target
DB14533Zinc chlorideIg kappa chain V-III region GOLtarget
DB14533Zinc chlorideImmunoglobulin lambda variable 3-21target
DB14533Zinc chlorideInter-alpha-trypsin inhibitor heavy chain H1target
DB14533Zinc chlorideInter-alpha-trypsin inhibitor heavy chain H2target
DB14533Zinc chlorideInter-alpha-trypsin inhibitor heavy chain H3target
DB14533Zinc chlorideInter-alpha-trypsin inhibitor heavy chain H4target
DB14533Zinc chlorideImmunoglobulin J chaintarget
DB14533Zinc chlorideJunction plakoglobintarget
DB14533Zinc chloridePlasma kallikreintarget
DB14533Zinc chlorideKininogen-1target
DB14533Zinc chlorideKeratin, type II cytoskeletal 1target
DB14533Zinc chlorideKeratin, type I cytoskeletal 10target
DB14533Zinc chlorideKeratin, type I cytoskeletal 14target
DB14533Zinc chlorideKeratin, type I cytoskeletal 16target
DB14533Zinc chlorideKeratin, type II cytoskeletal 2 epidermaltarget
DB14533Zinc chlorideKeratin, type II cytoskeletal 5target
DB14533Zinc chlorideKeratin, type II cytoskeletal 6Atarget
DB14533Zinc chlorideKeratin, type I cytoskeletal 9target
DB14533Zinc chlorideAlpha-1-acid glycoprotein 2target
DB14533Zinc chlorideN-acetylmuramoyl-L-alanine amidasetarget
DB14533Zinc chlorideSerum paraoxonase/arylesterase 1target
DB14533Zinc chloridePregnancy zone proteintarget
DB14533Zinc chlorideProtein S100-A7target
DB14533Zinc chlorideSelenoprotein Ptarget
DB14533Zinc chlorideAlpha-1-antitrypsintarget
DB14533Zinc chlorideAlpha-1-antichymotrypsintarget
DB14533Zinc chlorideKallistatintarget
DB14533Zinc chlorideCorticosteroid-binding globulintarget
DB14533Zinc chlorideHeparin cofactor 2target
DB14533Zinc chlorideSex hormone-binding globulintarget
DB14533Zinc chlorideSerotransferrintarget
DB14533Zinc chlorideTransthyretintarget
DB14533Zinc chlorideVitronectintarget
DB14533Zinc chlorideAmyloid-like protein 1target
DB14533Zinc chlorideAmyloid-like protein 2target
DB14533Zinc chlorideAmyloid beta A4 proteintarget
DB14533Zinc chloridePoly [ADP-ribose] polymerase 1target
DB14533Zinc chlorideCarboxypeptidase Eenzyme
DB14533Zinc chlorideAlcohol dehydrogenase 1Cenzyme
DB14533Zinc chlorideInsulin-degrading enzymeenzyme
DB14533Zinc chlorideSuperoxide dismutase [Cu-Zn]enzyme
DB14533Zinc chlorideCarbonic anhydrase 2enzyme
DB03904UreaArginase-1target
DB03904UreaCarbonic anhydrase 2target
DB03904UreaStructural polyproteintarget
DB03904UreaCatenin beta-1target
DB03904UreaSulfoxide reductase catalytic subunit YedYtarget
DB03904UreaDihydrofolate reductasetarget
DB03904UreaUrea transporter 2transporter
DB03904UreaUrea transporter 1transporter