Cardiac Therapy

DrugDrug NameDrug Description
DB00204DofetilideA class III antiarrhythmic drug used for the maintenance of normal sinus rhythm and cardioversion in cases of atrial fibrillation and atrial flutter.
DB00211MidodrineAn alpha-adrenergic antagonist used to treat orthostatic hypotension.
DB00235MilrinoneAn inotropic vasodilator agent used to treat acute, decompensated heart failure.
DB00243RanolazineAn anti-anginal drug used for the treatment of chronic angina.
DB00280DisopyramideA class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias.
DB00308IbutilideA class III antiarrhythmic agent used to correct atrial fibrillation and atrial flutter, which can be considered as an alternative to cardioversion.
DB00328IndomethacinA nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
DB00368NorepinephrineA sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest.
DB00379MexiletineA class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment.
DB00390DigoxinA cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation.
DB00511AcetyldigitoxinUsed for fast digitalization in congestive heart failure.
DB00610MetaraminolFor the treatment and prevention of hypotension due to hemorrhage, spinal anesthesia, and shock associated with brain damage
DB00640AdenosineA medication used in myocardial perfusion scintigraphy.
DB00680MoricizineAn antiarrhythmic used to treat arrhythmias.
DB00723MethoxamineAn alpha adrenergic agonist used to treat hypotension.
DB00727NitroglycerinA nitrate vasodilator used to treat or prevent angina, treat hypertension, control heart failure in myocardial infarction, and to induce hypotension intraoperatively.
DB00800FenoldopamA dopamine D1 receptor agonist used for the short term management of hypertension.
DB00841DobutamineA beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery.
DB00883Isosorbide dinitrateA vasodilator used to treat angina in coronary artery disease.
DB00908QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
DB00922LevosimendanFor short term treatment of acutely decompensated severe chronic heart failure (CHF). Also being investigated for use/treatment in heart disease.
DB00988DopamineA catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension.
DB01020Isosorbide mononitrateA nitrate used to prevent angina and to treat angina, hypertension, and myocardial infarction.
DB01035ProcainamideA medication used to treat life threatening ventricular arrhythmias.
DB01056TocainideAn orally active class 1b antiarrhythmic agent that interferes with cardiac sodium channels and typically used to treat ventricular arrhythmias.
DB01078DeslanosideFor the treatment and management of Congestive cardiac insufficiency, arrhythmias and heart failure.
DB01092OuabainFor the treatment of atrial fibrillation and flutter and heart failure
DB01102ArbutamineUsed to elicit acute cardiovascular responses (cardiac stumulant), similar to those produced by exercise, in order to aid in diagnosing the presence or absence of coronary artery disease (CAD) in...
DB01118AmiodaroneA class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation.
DB01182PropafenoneA Class 1C antiarrhythmic agent used in the management of paroxysmal atrial fibrillation/flutter and ventricular arrhythmias.
DB01195FlecainideA class Ic antiarrhythmic agent used to manage atrial fibrillation and paroxysmal supraventricular tachycardias (PSVT).
DB01228EncainideA voltage-gated sodium channel blocker used for management of atrial or ventricular fibrillation, atrial flutter, and ventricular tachycardia, that is no longer used due to proarrhythmic adverse effects.
DB01365MephentermineA sympathomimetic agent used in the treatment of hypotension.
DB01396DigitoxinA cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure.
DB01426AjmalineFor use as an antiarrhythmic agent.
DB01427AmrinoneA positive inotropic agent and phosphodiesterase inhibitor used in the management of treatment of congestive heart failure.
DB01429AprindineAprindine is a cardiac depressant used in arrhythmias.
DB01613Erythrityl tetranitrateFor the prevention of angina.
DB01744CamphorA compound used topically to help relieve pain and also as a topical antiseptic. May also be used in vaporizers to help suppress coughing. This medication should not be swallowed.
DB04825PrenylaminePrenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
DB04855DronedaroneAn antiarrhythmic agent used in the reduce the risk of hospitalization in patients with paroxysmal or persistent atrial fibrillation.
DB04880EnoximoneFor the treatment of congestive heart failure.
DB04899NesiritideA recombinant natriuretic peptide used for the treatment of patients with acutely decompensated congestive heart failure who have dyspnea at rest or with minimal activity.
DB04944AcadesineInvestigated for use/treatment in cardiac reperfusion injury, cardiovascular disorders, and coronary artery disease.
DB05794SerelaxinInvestigated for use/treatment in cardiovascular disorders, congestive heart failure, infertility, peripheral vascular disease, and scleroderma.
DB06154Pentaerythritol tetranitrateUsed for the treatment of angina pectoris .
DB06200TedisamilInvestigated for use/treatment in arrhythmia, atrial fibrillation, and angina.
DB06213RegadenosonA coronary vasodilator used in radionuclide myocardial perfusion imaging (MPI).
DB06217VernakalantAn antiarrhythmic medication used to treat patients with atrial fibrillation.
DB06262DroxidopaA medication used to treat symptomatic neurogenic orthostatic hypotension (nOH) caused by dopamine beta-hydroxylase deficiency, non-diabetic autonomic neuropathy and primary autonomic failure caused by conditions such as Parkinson's disease.
DB06727SparteineSparteine is a plant alkaloid derived from Cytisus scoparius and Lupinus mutabilis which may chelate calcium and magnesium. It is a sodium channel blocker so it falls under the category...
DB08985EtilefrineEtilefrine is an adrenergic agonist that appears to interact with beta-2 and some alpha adrenergic receptors. It has been used as a vasoconstrictor agent.
DB09069TrimetazidineTrimetazidine is indicated for use in angina pectoris.
DB09083IvabradineA HCN channel blocker used to reduce the risk of hospitalization for worsening heart failure in adult patients and for treatment of stable symptomatic heart failure as a result of dilated cardiomyopathy in pediatric patients.
DB09220NicorandilIndicated for the prevention and treatment of chronic stable angina pectoris and reduction in the risk of acute coronary syndromes.
DB09270UbidecarenoneA cofactor found in various dietary supplements.
DB09282MolsidomineThe indications for use of molsidomine include ischemic heart disease, angina, chronic heart failure, and pulmonary hypertension [L1370, L1371].
DB09283TrapidilUsed in the treatment of chronic stable angina .
DB09284ImolamineImolamine is indicated for the treatment of angina pectoris. The hydrochloride form is used as a local anesthetic.
DB12313DopexamineDopexamine has been used in trials studying the diagnostic and treatment of Free Flap, Oral Cancer, Hypotension, Septic Shock, and Head and Neck Cancer.
DB12926CafedrineCafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
DB12927TheodrenalineTheodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
DB13071CreatinolfosfateCOP is under investigation for the treatment of Rheumatoid Arthritis, Mature B-Cell Lymphoma, and Noninflammatory Degenerative Joint Disease. COP has been investigated for the treatment of Diabetic Retinopathy.
DB13191PhosphocreatinePhosphocreatine is a naturally occuring substance that is found predominantly in the skeletal muscles of vertebrates. Its primary utility within the body is to serve in the maintanence and recycling...
DB13228FlosequinanFlosequinan was approved in the USA and the UK for a year prior to being withdrawn from the market due to increased mortality in chronic heart failure patients, found in...
DB13240CymarinNot Annotated
DB13242BucladesineNot Annotated
DB13251OctopamineOctopamine is structurally similar to norepinephrine. It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World Anti-doping Agency (WADA) as...
DB13255Propatyl nitrateNot Annotated
DB13265HexobendineHexobendine is a medication used to cause vasodilation, to treat several conditions including angina pectoris. It has not been approved in the United States or the United Kingdom, but has...
DB13277BenziodaroneBenziodarone is a uricostatic and a uricosuric agent which is sold also under the name Amplivex-Labaz. It is used in the treatment of gout . It was withdrawn from France...
DB13279CarbocromenCarbocromen was marketed for use in Germany as a vasodilator, however, it has been discontinued due to the risk of arrhythmia development .
DB13291CloridarolCloridarol is an experimental medication in the treatment of heart disease, which acts through vasodilation. It was studied for the treatment of coronary insufficiency in Italy in the 1970s .
DB13307ProscillaridinProscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). Studies suggest the potential cytotoxic and anticancer property of proscillaridin,...
DB13330Amezinium metilsulfateNot Annotated
DB13333EfloxateNot Annotated
DB13342CinepazetNot Annotated
DB13358CibenzolineNot Annotated
DB13378NorfenefrineNot Annotated
DB13398OxyfedrineNot Annotated
DB13400LinsidomineNot Annotated
DB13401MetildigoxinNot Annotated
DB13408Methylpropylpropanediol dinitrateNot Annotated
DB13467Lanatoside CNot Annotated
DB13494DimetofrineNot Annotated
DB13517AngiotensinamideNot Annotated
DB13537GitoformateNot Annotated
DB13555PrajmalineNot Annotated
DB13574HeptaminolNot Annotated
DB13585Aminoethyl nitrateNot Annotated
DB13635TiracizineNot Annotated
DB13637TenitramineNot Annotated
DB13645EthacizineNot Annotated
DB13651LorajmineNot Annotated
DB13652BunaftineNot Annotated
DB13653LorcainideNot Annotated
DB13691AcetyldigoxinNot Annotated
DB13703GepefrineNot Annotated
DB13715DilazepNot Annotated
DB13719TrolnitrateNot Annotated
DB13723MeldoniumNot Annotated
DB13756PeruvosideNot Annotated
DB13777PrenalterolNot Annotated
DB13781XamoterolXamoterol is a β1-adrenoceptor partial agonist that has shown to improve systolic and diastolic function in studies with heart failure patients. It modulates the sympathetic control of the heart but...
DB13845EtafenoneEtafenone is a vasodilator.
DB13863FosfructoseNot Annotated
DB00281LidocaineA local anesthetic used in a wide variety of superficial and invasive procedures.
DB00388PhenylephrineAn alpha-1 adrenergic antagonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics.
DB00668EpinephrineA hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
DB00770AlprostadilA medication used to treat erectile dysfunction.
DB01064IsoprenalineA non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block; it is structurally related to epinephrine.
DB01364EphedrineAn alpha and beta-adrenergic agonist used for the management of respiratory conditions related to bronchial asthma, such as wheezing, shortness of breath, and tightness of chest.
DB09203SynephrineSynephrine, also referred to as, p-synephrine, is naturally occurring alkaloid. It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer...
DB13316IbopamineNot Annotated
DB01158BretyliumA norepinephrine release inhibitor used for the prophylaxis and therapy of ventricular fibrillation, as well as the treatment of life-threatening ventricular arrhythmias.
DB11842Angiotensin IIA peptide hormone of the RAAS system used to raise blood pressure in septic or other forms of shock.
DB15300HydroquinidineHydroquinidine is under investigation in clinical trial NCT00927732 (Hydroquinidine Versus Placebo in Patients With Brugada Syndrome).
DrugDrug NameTargetType
DB00204DofetilidePotassium channel subfamily K member 2target
DB00204DofetilidePotassium voltage-gated channel subfamily H member 2target
DB00204DofetilideATP-sensitive inward rectifier potassium channel 12target
DB00204DofetilideCytochrome P450 3A4enzyme
DB00204DofetilideSolute carrier family 22 member 2transporter
DB00211MidodrineAlpha-1A adrenergic receptortarget
DB00211MidodrineAlpha-1B adrenergic receptortarget
DB00211MidodrineCytochrome P450 2D6enzyme
DB00211MidodrineSolute carrier family 15 member 1transporter
DB00211MidodrineAlpha-1D adrenergic receptortarget
DB00235MilrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB00243RanolazineCytochrome P450 3A4enzyme
DB00243RanolazineCytochrome P450 2D6enzyme
DB00243RanolazineBile salt export pumptransporter
DB00243RanolazineP-glycoprotein 1transporter
DB00243RanolazineSodium channel proteintarget
DB00243RanolazineInward rectifier potassium channeltarget
DB00243RanolazineVoltage gated L-type calcium channeltarget
DB00243RanolazineAlpha-1 adrenergic receptorstarget
DB00243RanolazineBeta-1 adrenergic receptortarget
DB00243RanolazineFatty acidtarget
DB00243RanolazineAlpha-1-acid glycoprotein 1carrier
DB00280DisopyramideSodium channel protein type 5 subunit alphatarget
DB00280DisopyramideAlpha-1-acid glycoprotein 1carrier
DB00280DisopyramideCytochrome P450 3A4enzyme
DB00280DisopyramideMuscarinic acetylcholine receptor M1target
DB00280DisopyramideMuscarinic acetylcholine receptor M2target
DB00280DisopyramideMuscarinic acetylcholine receptor M3target
DB00280DisopyramidePotassium voltage-gated channel subfamily D member 2target
DB00280DisopyramidePotassium voltage-gated channel subfamily D member 3target
DB00280DisopyramideSolute carrier family 22 member 2transporter
DB00280DisopyramideSolute carrier family 22 member 1transporter
DB00280DisopyramidePotassium voltage-gated channel subfamily H member 2target
DB00280DisopyramideAlpha-1-acid glycoprotein 2target
DB00280DisopyramideCytochrome P450 1A2enzyme
DB00308IbutilidePotassium voltage-gated channel subfamily H member 6target
DB00308IbutilideVoltage-dependent L-type calcium channel subunit beta-1target
DB00308IbutilideVoltage-dependent calcium channel gamma-1 subunittarget
DB00308IbutilideVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00308IbutilidePotassium voltage-gated channel subfamily H member 2target
DB00308IbutilideVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00308IbutilidePotassium channel subfamily K member 1target
DB00308IbutilidePotassium channel subfamily K member 6target
DB00308IbutilideATP-sensitive inward rectifier potassium channel 11target
DB00308IbutilidePotassium voltage-gated channel subfamily H member 7target
DB00328IndomethacinProstaglandin G/H synthase 1target
DB00328IndomethacinProstaglandin G/H synthase 2target
DB00328IndomethacinCytochrome P450 2C19enzyme
DB00328IndomethacinUDP-glucuronosyltransferase 1-9enzyme
DB00328IndomethacinPhospholipase A2, membrane associatedtarget
DB00328IndomethacinProstaglandin reductase 2target
DB00328IndomethacinLactoylglutathione lyasetarget
DB00328IndomethacinProstaglandin D2 receptor 2target
DB00328IndomethacinPeroxisome proliferator-activated receptor gammatarget
DB00328IndomethacinSerum albumincarrier
DB00328IndomethacinCanalicular multispecific organic anion transporter 2transporter
DB00328IndomethacinMultidrug resistance-associated protein 4transporter
DB00328IndomethacinMultidrug resistance-associated protein 6transporter
DB00328IndomethacinP-glycoprotein 1transporter
DB00328IndomethacinMultidrug resistance-associated protein 1transporter
DB00328IndomethacinSolute carrier organic anion transporter family member 1A2transporter
DB00328IndomethacinSolute carrier family 22 member 6transporter
DB00328IndomethacinSolute carrier family 22 member 8transporter
DB00328IndomethacinCanalicular multispecific organic anion transporter 1transporter
DB00328IndomethacinATP-binding cassette sub-family C member 11transporter
DB00328IndomethacinSolute carrier family 22 member 11transporter
DB00328IndomethacinSodium/bile acid cotransportertransporter
DB00328IndomethacinSolute carrier family 22 member 7transporter
DB00328IndomethacinCytochrome P450 2C9enzyme
DB00328IndomethacinUDP-glucuronosyltransferase 1-1enzyme
DB00328IndomethacinLiver carboxylesterase 1enzyme
DB00328IndomethacinUDP-glucuronosyltransferase 2B7enzyme
DB00328IndomethacinPeroxisome proliferator-activated receptor alphatarget
DB00328IndomethacinAldo-keto reductase family 1 member C3target
DB00328IndomethacinSolute carrier organic anion transporter family member 1B1transporter
DB00328IndomethacinBile salt export pumptransporter
DB00368NorepinephrinePhenylalanine-4-hydroxylasetarget
DB00368NorepinephrineAlpha-1A adrenergic receptortarget
DB00368NorepinephrineAlpha-1B adrenergic receptortarget
DB00368NorepinephrineAlpha-1D adrenergic receptortarget
DB00368NorepinephrineAlpha-2A adrenergic receptortarget
DB00368NorepinephrineAlpha-2B adrenergic receptortarget
DB00368NorepinephrineAlpha-2C adrenergic receptortarget
DB00368NorepinephrineBeta-1 adrenergic receptortarget
DB00368NorepinephrineBeta-2 adrenergic receptortarget
DB00368NorepinephrineBeta-3 adrenergic receptortarget
DB00368NorepinephrineSolute carrier family 22 member 2transporter
DB00368NorepinephrineSolute carrier family 22 member 3transporter
DB00368NorepinephrineSolute carrier family 22 member 5transporter
DB00368NorepinephrineSolute carrier family 22 member 1transporter
DB00368NorepinephrinePOU domain, class 5, transcription factor 1transporter
DB00368NorepinephrineSodium-dependent noradrenaline transportertransporter
DB00368NorepinephrineSynaptic vesicular amine transportertarget
DB00368NorepinephrineChromaffin granule amine transportertarget
DB00379MexiletineSodium channel protein type 5 subunit alphatarget
DB00379MexiletineCytochrome P450 1A2enzyme
DB00379MexiletineCytochrome P450 2D6enzyme
DB00379MexiletineCytochrome P450 2B6enzyme
DB00379MexiletineCytochrome P450 2E1enzyme
DB00379MexiletineCytochrome P450 3A4enzyme
DB00379MexiletineAryl hydrocarbon receptortarget
DB00390DigoxinSodium/potassium-transporting ATPase subunit alpha-1target
DB00390DigoxinCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB00390DigoxinP-glycoprotein 1transporter
DB00390DigoxinSolute carrier organic anion transporter family member 4C1transporter
DB00390DigoxinBile salt export pumptransporter
DB00390DigoxinSolute carrier organic anion transporter family member 1A2transporter
DB00390DigoxinOrganic solute transporter subunit alphatransporter
DB00390DigoxinOrganic solute transporter subunit betatransporter
DB00390DigoxinSolute carrier organic anion transporter family member 1B1transporter
DB00511AcetyldigitoxinSodium/potassium-transporting ATPase subunit alpha-1target
DB00610MetaraminolAlpha-1A adrenergic receptortarget
DB00640AdenosineAdenosine receptor A3target
DB00640AdenosineAdenosine deaminaseenzyme
DB00640AdenosineAdenosine kinaseenzyme
DB00640AdenosineAdenosine receptor A1target
DB00640AdenosineAdenosine receptor A2atarget
DB00640AdenosineAdenosine receptor A2btarget
DB00640AdenosineSolute carrier family 28 member 3transporter
DB00680MoricizineSodium channel protein type 5 subunit alphatarget
DB00723MethoxamineAlpha-1A adrenergic receptortarget
DB00723MethoxamineAlpha-1B adrenergic receptortarget
DB00723MethoxamineAlpha-1D adrenergic receptortarget
DB00727NitroglycerinAtrial natriuretic peptide receptor 1target
DB00727NitroglycerinAldehyde dehydrogenase, mitochondrialenzyme
DB00800FenoldopamDopamine D5 receptortarget
DB00800FenoldopamDopamine D1 receptortarget
DB00800FenoldopamAlpha-2B adrenergic receptortarget
DB00800FenoldopamAlpha-2C adrenergic receptortarget
DB00800FenoldopamAlpha-2A adrenergic receptortarget
DB00800FenoldopamAlpha-1B adrenergic receptortarget
DB00800FenoldopamAlpha-1D adrenergic receptortarget
DB00800FenoldopamAlpha-1A adrenergic receptortarget
DB00841DobutamineBeta-1 adrenergic receptortarget
DB00841DobutamineCatechol O-methyltransferaseenzyme
DB00841DobutamineBeta-2 adrenergic receptortarget
DB00841DobutamineAlpha-1 adrenergic receptorstarget
DB00841DobutamineEstrogen receptor alphatarget
DB00883Isosorbide dinitrateAtrial natriuretic peptide receptor 1target
DB00883Isosorbide dinitrateCytochrome P450 2E1enzyme
DB00908QuinidineSodium channel protein type 5 subunit alphatarget
DB00908QuinidineAlpha-1-acid glycoprotein 1carrier
DB00908QuinidinePotassium voltage-gated channel subfamily H member 2target
DB00908QuinidinePotassium channel subfamily K member 1target
DB00908QuinidinePotassium channel subfamily K member 6target
DB00908QuinidineCytochrome P450 1A2enzyme
DB00908QuinidineCytochrome P450 2E1enzyme
DB00908QuinidineCytochrome P450 1A1enzyme
DB00908QuinidineCytochrome P450 2D6enzyme
DB00908QuinidineCytochrome P450 3A4enzyme
DB00908QuinidineCytochrome P450 3A7enzyme
DB00908QuinidineSolute carrier family 22 member 2transporter
DB00908QuinidineSolute carrier family 22 member 1transporter
DB00908QuinidineSolute carrier family 22 member 5transporter
DB00908QuinidineP-glycoprotein 1transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1A2transporter
DB00908QuinidineSolute carrier family 22 member 8transporter
DB00908QuinidineCanalicular multispecific organic anion transporter 1transporter
DB00908QuinidineSolute carrier family 22 member 4transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1B1transporter
DB00908QuinidineCytochrome P450 2B6enzyme
DB00908QuinidineCytochrome P450 2C9enzyme
DB00908QuinidineAlpha-1A adrenergic receptortarget
DB00908QuinidineAlpha-1B adrenergic receptortarget
DB00908QuinidineAlpha-1D adrenergic receptortarget
DB00908QuinidineBile salt export pumptransporter
DB00908QuinidineCytochrome P450 2C8enzyme
DB00922LevosimendanTroponin C, slow skeletal and cardiac musclestarget
DB00922LevosimendanATP-sensitive inward rectifier potassium channel 11target
DB00922LevosimendanATP-sensitive inward rectifier potassium channel 8target
DB00922LevosimendancGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB00988DopamineDopamine D1 receptortarget
DB00988DopamineDopamine beta-hydroxylasetarget
DB00988DopamineAmine oxidase [flavin-containing] Aenzyme
DB00988DopamineAmine oxidase [flavin-containing] Benzyme
DB00988DopamineCatechol O-methyltransferaseenzyme
DB00988DopamineSolute carrier family 22 member 2transporter
DB00988DopamineSolute carrier family 22 member 1transporter
DB00988DopamineSolute carrier family 22 member 3transporter
DB00988DopamineSolute carrier family 22 member 5transporter
DB00988DopaminePOU domain, class 5, transcription factor 1transporter
DB00988DopamineDopamine D5 receptortarget
DB00988DopamineDopamine D2 receptortarget
DB00988DopamineDopamine D3 receptortarget
DB00988DopamineDopamine D4 receptortarget
DB00988DopamineSodium-dependent dopamine transportertarget
DB00988DopamineDopamine beta-hydroxylaseenzyme
DB00988Dopamine5-hydroxytryptamine receptor 1Atarget
DB00988Dopamine5-hydroxytryptamine receptor 7target
DB00988DopamineD(1) dopamine receptortarget
DB00988DopamineSodium-dependent noradrenaline transportertarget
DB00988DopamineSodium-dependent serotonin transportertarget
DB00988Dopamine5-hydroxytryptamine receptor 3Atarget
DB00988Dopamine5-hydroxytryptamine receptor 3Btarget
DB00988DopamineSuperoxide dismutase [Cu-Zn]target
DB00988DopamineSynaptic vesicular amine transportertarget
DB01020Isosorbide mononitrateGuanylate cyclase soluble subunit alpha-2target
DB01035ProcainamideSodium channel protein type 5 subunit alphatarget
DB01035ProcainamideDNA (cytosine-5)-methyltransferase 1target
DB01035ProcainamideCytochrome P450 2D6enzyme
DB01035ProcainamideCholinesteraseenzyme
DB01035ProcainamideSolute carrier family 22 member 2transporter
DB01035ProcainamideSolute carrier family 22 member 1transporter
DB01035ProcainamideSolute carrier family 22 member 3transporter
DB01035ProcainamideSolute carrier family 22 member 5transporter
DB01035ProcainamideSolute carrier family 22 member 4transporter
DB01035ProcainamidePotassium voltage-gated channel subfamily H member 2target
DB01035ProcainamideMultidrug and toxin extrusion protein 1transporter
DB01035ProcainamideMultidrug and toxin extrusion protein 2transporter
DB01056TocainideSodium channel protein type 5 subunit alphatarget
DB01056TocainideSerum albumincarrier
DB01056TocainideCytochrome P450 1A2enzyme
DB01078DeslanosideSodium/potassium-transporting ATPase subunit alpha-1target
DB01092OuabainSodium/potassium-transporting ATPase subunit alpha-1target
DB01092OuabainSolute carrier organic anion transporter family member 1A2transporter
DB01092OuabainSolute carrier family 22 member 8transporter
DB01092OuabainSolute carrier organic anion transporter family member 4C1transporter
DB01092OuabainSolute carrier organic anion transporter family member 1B3transporter
DB01092OuabainSolute carrier organic anion transporter family member 1C1transporter
DB01092OuabainSolute carrier organic anion transporter family member 1B1transporter
DB01092OuabainSodium/potassium-transporting ATPase subunit alpha-2target
DB01092OuabainSodium/potassium-transporting ATPase subunit alpha-3target
DB01102ArbutamineBeta-1 adrenergic receptortarget
DB01102ArbutamineBeta-2 adrenergic receptortarget
DB01102ArbutamineBeta-3 adrenergic receptortarget
DB01118AmiodaroneBeta adrenergic receptortarget
DB01118AmiodaroneHERG human cardiac K+ channeltarget
DB01118AmiodaroneCytochrome P450 2C8enzyme
DB01118AmiodaroneCytochrome P450 2C9enzyme
DB01118AmiodaroneCytochrome P450 2D6enzyme
DB01118AmiodaroneVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB01118AmiodaroneVoltage gated L-type calcium channeltarget
DB01118AmiodaroneCytochrome P450 3A4enzyme
DB01118AmiodaroneCytochrome P450 1A2enzyme
DB01118AmiodaroneCytochrome P450 1A1enzyme
DB01118AmiodaroneP-glycoprotein 1transporter
DB01118AmiodaroneCytochrome P450 2C19enzyme
DB01118AmiodaroneCytochrome P450 2A6enzyme
DB01118AmiodaroneThyroid hormone receptortarget
DB01118AmiodaronePeroxisome proliferator-activated receptor gammatarget
DB01118AmiodaroneBile salt export pumptransporter
DB01118AmiodaroneSolute carrier family 22 member 2transporter
DB01118AmiodaroneCytochrome P450 2J2enzyme
DB01118AmiodaronePeroxisome proliferator-activated receptor alphatarget
DB01118AmiodaronePeroxisome proliferator-activated receptor gamma coactivator 1-betatarget
DB01118AmiodaroneSerum albumincarrier
DB01182PropafenoneSodium channel protein type 5 subunit alphatarget
DB01182PropafenonePotassium voltage-gated channel subfamily H member 2target
DB01182PropafenoneCytochrome P450 1A2enzyme
DB01182PropafenoneCytochrome P450 2D6enzyme
DB01182PropafenoneCytochrome P450 3A4enzyme
DB01182PropafenoneP-glycoprotein 1transporter
DB01182PropafenoneBeta-1 adrenergic receptortarget
DB01182PropafenoneBeta-2 adrenergic receptortarget
DB01195FlecainideSodium channel protein type 5 subunit alphatarget
DB01195FlecainideCytochrome P450 2D6enzyme
DB01195FlecainideSodium channel protein type 4 subunit alphatarget
DB01195FlecainideCytochrome P450 2C9enzyme
DB01195FlecainidePotassium voltage-gated channel subfamily H member 2target
DB01195Flecainidealpha1-acid glycoproteincarrier
DB01195FlecainideSerum albumincarrier
DB01195FlecainideCytochrome P450 1A2enzyme
DB01195FlecainideP-glycoprotein 1transporter
DB01195FlecainideMultidrug and toxin extrusion protein 1transporter
DB01195FlecainideRyanodine receptor 2target
DB01228EncainideSodium channel protein type 5 subunit alphatarget
DB01228EncainideCytochrome P450 2D6enzyme
DB01365MephentermineAlpha adrenergic receptortarget
DB01365MephentermineBeta adrenergic receptortarget
DB01396DigitoxinSodium/potassium-transporting ATPase subunit alpha-1target
DB01396DigitoxinSerum albumincarrier
DB01396DigitoxinCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB01396DigitoxinCytochrome P450 3A4enzyme
DB01396DigitoxinSolute carrier organic anion transporter family member 1A2transporter
DB01396DigitoxinSolute carrier organic anion transporter family member 4C1transporter
DB01396DigitoxinP-glycoprotein 1transporter
DB01426AjmalineAlpha-1-acid glycoprotein 1carrier
DB01426AjmalineSodium channel protein type 5 subunit alphatarget
DB01427AmrinonecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB01427AmrinoneTumor necrosis factortarget
DB01427AmrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB01427AmrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Btarget
DB01429AprindineAlpha-1-acid glycoprotein 1carrier
DB01429AprindineCalmodulintarget
DB01429AprindineSodium channel protein type 5 subunit alphatarget
DB01429AprindineCytochrome P450 2D6enzyme
DB01613Erythrityl tetranitrateAtrial natriuretic peptide receptor 1target
DB01613Erythrityl tetranitrateAtrial natriuretic peptide receptor 2target
DB01744CamphorCamphor 5-monooxygenasetarget
DB01744CamphorTransient receptor potential cation channel subfamily V member 1target
DB01744CamphorTransient receptor potential cation channel subfamily V member 3target
DB01744CamphorTransient receptor potential cation channel subfamily A member 1target
DB01744CamphorTransient receptor potential cation channel subfamily M member 8target
DB04825PrenylamineCalmodulintarget
DB04825PrenylamineMyosin light chain kinase 2, skeletal/cardiac muscletarget
DB04825PrenylamineCytochrome P450 3A4enzyme
DB04855DronedaroneAlpha-1A adrenergic receptortarget
DB04855DronedaroneBeta-1 adrenergic receptortarget
DB04855DronedaroneAlpha-1B adrenergic receptortarget
DB04855DronedaroneAlpha-1D adrenergic receptortarget
DB04855DronedaroneAlpha-2A adrenergic receptortarget
DB04855DronedaroneAlpha-2B adrenergic receptortarget
DB04855DronedaroneAlpha-2C adrenergic receptortarget
DB04855DronedaronePotassium voltage-gated channel subfamily H member 2target
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Ftarget
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit beta-1target
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit beta-2target
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit beta-3target
DB04855DronedaroneVoltage-dependent L-type calcium channel subunit beta-4target
DB04855DronedaroneCytochrome P450 2D6enzyme
DB04855DronedaroneCytochrome P450 3A4enzyme
DB04855DronedaroneP-glycoprotein 1transporter
DB04855DronedaronePotassium channel subfamily K member 2target
DB04855DronedaroneSerum albumincarrier
DB04855DronedaroneSolute carrier family 22 member 2transporter
DB04855DronedaroneSolute carrier family 22 member 1transporter
DB04855DronedaroneSolute carrier organic anion transporter family member 1B1transporter
DB04855DronedaroneSolute carrier organic anion transporter family member 1B3transporter
DB04855DronedaroneSolute carrier family 22 member 8transporter
DB04855DronedaroneCytochrome P450 3A5enzyme
DB04855DronedaroneCytochrome P450 2J2enzyme
DB04855DronedaroneThyroid hormone receptor alphatarget
DB04855DronedaroneSodium channel protein type 5 subunit alphatarget
DB04855DronedaroneG protein-activated inward rectifier potassium channel 1target
DB04855DronedaronePotassium voltage-gated channel subfamily KQT member 1target
DB04855DronedaroneInward rectifier potassium channeltarget
DB04855DronedaroneSodium/calcium exchanger 1target
DB04855DronedaronePotassium voltage-gated channel subfamily D member 3target
DB04880EnoximonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
DB04899NesiritideAtrial natriuretic peptide receptor 1target
DB04899NesiritideAtrial natriuretic peptide receptor 2target
DB04899NesiritideAtrial natriuretic peptide receptor 3target
DB06154Pentaerythritol tetranitrateHemoglobin subunit alphatarget
DB06154Pentaerythritol tetranitrateHemoglobin subunit betatarget
DB06154Pentaerythritol tetranitrateGuanylate cyclase soluble subunit alpha-2enzyme
DB06154Pentaerythritol tetranitrateFree radicalstarget
DB06154Pentaerythritol tetranitrateNitric oxide synthase, endothelialenzyme
DB06154Pentaerythritol tetranitrateAldehyde dehydrogenase, mitochondrialenzyme
DB06213RegadenosonAdenosine receptor A2atarget
DB06217VernakalantCytochrome P450 2D6enzyme
DB06217VernakalantSodium channel protein type 5 subunit alphatarget
DB06217VernakalantPotassium voltage-gated channel subfamily A member 5target
DB06217VernakalantPotassium voltage-gated channel subfamily D member 3target
DB06217VernakalantPotassium voltage-gated channel subfamily H member 2target
DB06262DroxidopaPhenylalanine-4-hydroxylasetarget
DB06262DroxidopaAlpha-1A adrenergic receptortarget
DB06262DroxidopaAlpha-1B adrenergic receptortarget
DB06262DroxidopaAlpha-1D adrenergic receptortarget
DB06262DroxidopaAlpha-2A adrenergic receptortarget
DB06262DroxidopaAlpha-2B adrenergic receptortarget
DB06262DroxidopaAlpha-2C adrenergic receptortarget
DB06262DroxidopaBeta-1 adrenergic receptortarget
DB06262DroxidopaBeta-2 adrenergic receptortarget
DB06262DroxidopaBeta-3 adrenergic receptortarget
DB06262DroxidopaAromatic-L-amino-acid decarboxylaseenzyme
DB06262DroxidopaMonocarboxylate transporter 10transporter
DB06262DroxidopaSodium-dependent noradrenaline transportertransporter
DB06727SparteineCytochrome P450 2D6enzyme
DB09069Trimetazidine3-ketoacyl-CoA thiolase, peroxisomaltarget
DB09083IvabradineCytochrome P450 3A4enzyme
DB09083IvabradinePotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2target
DB09220NicorandilATP-binding cassette sub-family C member 9target
DB09270UbidecarenoneNADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrialtarget
DB09270UbidecarenoneSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialtarget
DB09270UbidecarenoneLow-density lipoprotein receptorcarrier
DB09270UbidecarenoneVery low-density lipoprotein receptorcarrier
DB09270UbidecarenoneP-glycoprotein 1transporter
DB09270Ubidecarenone3-hydroxy-3-methylglutaryl-coenzyme A reductaseenzyme
DB09282MolsidomineGuanylate cyclase soluble subunit alpha-2target
DB09282MolsidomineGuanylate cyclase soluble subunit alpha-2enzyme
DB09282MolsidominecGMP-specific 3',5'-cyclic phosphodiesteraseenzyme
DB09283TrapidilPlatelet-derived growth factor receptor betatarget
DB09283TrapidilCyclic nucleotide phosphodiesterasetarget
DB13191PhosphocreatineGuanidinoacetate N-methyltransferasetarget
DB13191PhosphocreatineSodium- and chloride-dependent creatine transporter 1target
DB13191PhosphocreatineCreatine kinase M-typetarget
DB13191PhosphocreatineCreatine kinase U-type, mitochondrialtarget
DB13191PhosphocreatineCreatine kinase S-type, mitochondrialtarget
DB13191PhosphocreatineCreatine kinase B-typetarget
DB13781XamoterolBeta-1 adrenergic receptortarget
DB00281LidocaineSodium channel protein type 5 subunit alphatarget
DB00281LidocaineSodium channel protein type 10 subunit alphatarget
DB00281LidocaineEpidermal growth factor receptortarget
DB00281LidocaineSodium channel protein type 9 subunit alphatarget
DB00281LidocaineCytochrome P450 1A2enzyme
DB00281LidocaineCytochrome P450 2D6enzyme
DB00281LidocaineCytochrome P450 3A4enzyme
DB00281LidocaineCytochrome P450 3A5enzyme
DB00281LidocaineCytochrome P450 3A7enzyme
DB00281LidocaineSolute carrier family 22 member 5transporter
DB00281LidocaineP-glycoprotein 1transporter
DB00281LidocaineCytochrome P450 2A6enzyme
DB00281LidocaineCytochrome P450 2B6enzyme
DB00281LidocaineCytochrome P450 2C8enzyme
DB00281LidocaineCytochrome P450 2C9enzyme
DB00281LidocaineSodium channel protein type 4 subunit alphatarget
DB00281LidocaineAlpha-1-acid glycoprotein 1target
DB00281LidocaineAlpha-1-acid glycoprotein 2target
DB00388PhenylephrineAlpha-1A adrenergic receptortarget
DB00388PhenylephrineAlpha-1B adrenergic receptortarget
DB00388PhenylephrineAmine oxidase [flavin-containing] Aenzyme
DB00388PhenylephrineAlpha-1D adrenergic receptortarget
DB00388PhenylephrineCytochrome P450 1A2enzyme
DB00388PhenylephrineSulfotransferase 1A3/1A4enzyme
DB00388PhenylephrineAmine oxidase [flavin-containing] Benzyme
DB00668EpinephrineAlpha-1A adrenergic receptortarget
DB00668EpinephrineBeta-1 adrenergic receptortarget
DB00668EpinephrineBeta-2 adrenergic receptortarget
DB00668EpinephrineSolute carrier family 22 member 2transporter
DB00668EpinephrineSolute carrier family 22 member 1transporter
DB00668EpinephrineCytochrome P450 2C9enzyme
DB00668EpinephrineCytochrome P450 3A4enzyme
DB00668EpinephrineAlpha-1B adrenergic receptortarget
DB00668EpinephrineAlpha-1D adrenergic receptortarget
DB00668EpinephrineAlpha-2A adrenergic receptortarget
DB00668EpinephrineAlpha-2B adrenergic receptortarget
DB00668EpinephrineTumor necrosis factortarget
DB00668EpinephrineCatechol O-methyltransferaseenzyme
DB00668EpinephrineMonoamine oxidaseenzyme
DB00770AlprostadilProstaglandin E2 receptor EP2 subtypetarget
DB00770AlprostadilProstaglandin E2 receptor EP1 subtypetarget
DB00770AlprostadilMultidrug resistance-associated protein 5transporter
DB00770AlprostadilSolute carrier organic anion transporter family member 2B1transporter
DB00770AlprostadilSolute carrier organic anion transporter family member 3A1transporter
DB00770AlprostadilMultidrug resistance-associated protein 4transporter
DB00770AlprostadilSolute carrier organic anion transporter family member 2A1transporter
DB00770AlprostadilProstaglandin D2 receptor 2target
DB00770AlprostadilSolute carrier family 22 member 6transporter
DB01064IsoprenalineBeta-1 adrenergic receptortarget
DB01064IsoprenalineBeta-2 adrenergic receptortarget
DB01064IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit alphatarget
DB01064IsoprenalineBeta-3 adrenergic receptortarget
DB01064IsoprenalineMitogen-activated protein kinase 1target
DB01064IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit betatarget
DB01064IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit gammatarget
DB01064IsoprenalineCytochrome P450 1A1enzyme
DB01064IsoprenalineCAMP phosphodiesterasetarget
DB01064IsoprenalineSuperoxide dismutase [Cu-Zn]target
DB01364EphedrineAcetylcholinesterasetarget
DB01364EphedrineAlpha-1A adrenergic receptortarget
DB01364EphedrineSodium-dependent noradrenaline transportertarget
DB01364EphedrineSynaptic vesicular amine transportertarget
DB01364EphedrineCholinesteraseenzyme
DB09203SynephrineAlpha-1 adrenergic receptorstarget
DB01158BretyliumSodium/potassium-transporting ATPase subunit alpha-1target
DB11842Angiotensin IIType-1 angiotensin II receptortarget