Showing BioInteractions for Lasofoxifene (DB06202)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.

Target Mediated Interactions 5

	Interacting Group	Interacting Drugs
	Lasofoxifene is a Estrogen receptor alpha antagonist
1	Estrogen receptor alpha agonists	Allylestrenol, Bazedoxifene, Chlorotrianisene, Clomifene, Conjugated estrogens, Danazol, Desogestrel, Dienestrol, Diethylstilbestrol, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estramustine, Estriol, Estrone, Estrone sulfate, Ethinylestradiol, Ethynodiol diacetate, Gestrinone, Medroxyprogesterone acetate, Mestranol, Norgestimate, Ospemifene, Phenolphthalein, Polyestradiol phosphate, Progesterone, Quinestrol, Raloxifene, Tamoxifen, Tibolone
2	Estrogen receptor alpha modulators	Quinestrol, Toremifene
3	Estrogen receptor alpha antagonists	Bazedoxifene, Clomifene, Fluoxymesterone, Fulvestrant, Gestrinone, Melatonin, Naloxone, Ospemifene, Tamoxifen, Tibolone
4	Estrogen receptor alpha inhibitors	Progesterone, Testosterone
5	Estrogen receptor alpha binders	Fluoroestradiol F-18, Prasterone, Zinc chloride, Zinc sulfate, unspecified form
6	Estrogen receptor alpha ligands	Synthetic Conjugated Estrogens, A, Synthetic Conjugated Estrogens, B
7	Estrogen receptor alpha cofactors	Zinc

	Interacting Group	Interacting Drugs
	Lasofoxifene is a Estrogen receptor alpha agonist
1	Estrogen receptor alpha agonists	Allylestrenol, Bazedoxifene, Chlorotrianisene, Clomifene, Conjugated estrogens, Danazol, Desogestrel, Dienestrol, Diethylstilbestrol, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estramustine, Estriol, Estrone, Estrone sulfate, Ethinylestradiol, Ethynodiol diacetate, Gestrinone, Medroxyprogesterone acetate, Mestranol, Norgestimate, Ospemifene, Phenolphthalein, Polyestradiol phosphate, Progesterone, Quinestrol, Raloxifene, Tamoxifen, Tibolone
2	Estrogen receptor alpha modulators	Quinestrol, Toremifene
3	Estrogen receptor alpha antagonists	Bazedoxifene, Clomifene, Fluoxymesterone, Fulvestrant, Gestrinone, Melatonin, Naloxone, Ospemifene, Tamoxifen, Tibolone
4	Estrogen receptor alpha inhibitors	Progesterone, Testosterone
5	Estrogen receptor alpha binders	Fluoroestradiol F-18, Prasterone, Zinc chloride, Zinc sulfate, unspecified form
6	Estrogen receptor alpha ligands	Synthetic Conjugated Estrogens, A, Synthetic Conjugated Estrogens, B
7	Estrogen receptor alpha cofactors	Zinc

	Interacting Group	Interacting Drugs
	Lasofoxifene is a Estrogen receptor alpha negative modulator
1	Estrogen receptor alpha agonists	Allylestrenol, Bazedoxifene, Chlorotrianisene, Clomifene, Conjugated estrogens, Danazol, Desogestrel, Dienestrol, Diethylstilbestrol, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estramustine, Estriol, Estrone, Estrone sulfate, Ethinylestradiol, Ethynodiol diacetate, Gestrinone, Medroxyprogesterone acetate, Mestranol, Norgestimate, Ospemifene, Phenolphthalein, Polyestradiol phosphate, Progesterone, Quinestrol, Raloxifene, Tamoxifen, Tibolone
2	Estrogen receptor alpha modulators	Quinestrol, Toremifene
3	Estrogen receptor alpha antagonists	Bazedoxifene, Clomifene, Fluoxymesterone, Fulvestrant, Gestrinone, Melatonin, Naloxone, Ospemifene, Tamoxifen, Tibolone
4	Estrogen receptor alpha inhibitors	Progesterone, Testosterone
5	Estrogen receptor alpha binders	Fluoroestradiol F-18, Prasterone, Zinc chloride, Zinc sulfate, unspecified form
6	Estrogen receptor alpha ligands	Synthetic Conjugated Estrogens, A, Synthetic Conjugated Estrogens, B
7	Estrogen receptor alpha cofactors	Zinc

	Interacting Group	Interacting Drugs
	Lasofoxifene is a Estrogen receptor beta agonist
1	Estrogen receptor beta agonists	5-Alpha-Androstane-3-Beta,17beta-Diol, Conjugated estrogens, Diethylstilbestrol, Equol, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estriol, Estrone sulfate, Progesterone, Raloxifene, Tamoxifen
2	Estrogen receptor beta antagonists	Tamoxifen
3	Estrogen receptor beta activators	Prasterone
4	Estrogen receptor beta partial agonists	Naringenin
5	Estrogen receptor beta binders	Fluoroestradiol F-18

	Interacting Group	Interacting Drugs
	Lasofoxifene is a Cannabinoid receptor 2 inverse agonist
1	Cannabinoid receptor 2 partial agonists	Nabilone, Tetrahydrocannabivarin
2	Cannabinoid receptor 2 agonists	Dronabinol
3	Cannabinoid receptor 2 antagonists	Cannabidiol