Heartburn

Also known as: [D]Heartburn / Pyrosis / Indigestion / Dyspepsia

DrugDrug NameDrug Description
DB13595AlmasilateAlmasilate is indicated for use as an antacid for the neutralization of excess stomach acid . It is subsequently also used for the symptomatic treatment of diseases where it is...
DB06723Aluminum hydroxideAn antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach.
DB01294Bismuth subsalicylateAn antidiarrheal and anti-inflammatory agent used for symptomatic treatment of nausea, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
DB06724Calcium carbonateAn ionic compound used as a calcium supplement or antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach.
DB00501CimetidineA histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
DB04272Citric acidAn anti-chelation additive used in blood collection tubes and as a flavoring and preservative agent in various cosmetic and pharmaceutical products.
DB05351DexlansoprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
DB00736EsomeprazoleA proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion.
DB00927FamotidineA histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.
DB09459L-tartaric acidTartaric Acid is primarily indicated in conditions like Antiscorbutic, Antiseptic.
DB08938MagaldrateAn antacid used to treat various conditions in the GI tract, such as esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux.
DB09481Magnesium carbonateAn antacid used for symptomatic relief of heartburn, indigestion, and upset stomach.
DB09104Magnesium hydroxideAn inorganic compound used as a laxative and antacid.
DB01377Magnesium oxideA compound commonly used as a laxative for the symptomatic relief of acid indigestion and upset stomach, and in health supplements for cardiovascular and neuromuscular health.
DB09281Magnesium trisilicateAn antacid used for the symptomatic treatment of peptic ulcers.
DB00338OmeprazoleA proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection.
DB01129RabeprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
DB00863RanitidineA histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis.
DB14116SilodrateNot Annotated
DB01390Sodium bicarbonateA compound used for the symptomatic treatment of heartburn, acid indigestion, and upset stomach as well as the treatment of metabolic acidosis associated with conditions such as severe renal disease and circulatory insufficiency due to shock.
DB09154Sodium citrateAn ingredient used for the anticoagulation of whole blood as part of automated apheresis procedures.
DrugDrug NameTargetType
DB01294Bismuth subsalicylateSerum albumincarrier
DB01294Bismuth subsalicylateSerotransferrincarrier
DB00501CimetidineHistamine H2 receptortarget
DB00501CimetidineCytochrome P450 1A2enzyme
DB00501CimetidineCytochrome P450 2D6enzyme
DB00501CimetidineCytochrome P450 2C19enzyme
DB00501CimetidineCytochrome P450 3A4enzyme
DB00501CimetidineCytochrome P450 3A5enzyme
DB00501CimetidineP-glycoprotein 1transporter
DB00501CimetidineSolute carrier family 22 member 2transporter
DB00501CimetidineSolute carrier family 22 member 1transporter
DB00501CimetidineSolute carrier family 22 member 3transporter
DB00501CimetidineSolute carrier family 22 member 5transporter
DB00501CimetidineSolute carrier family 22 member 6transporter
DB00501CimetidineSolute carrier family 22 member 8transporter
DB00501CimetidineMultidrug and toxin extrusion protein 1transporter
DB00501CimetidineSolute carrier family 22 member 4transporter
DB00501CimetidineSolute carrier family 22 member 11transporter
DB00501CimetidineSolute carrier family 22 member 7transporter
DB00501CimetidineCytochrome P450 11B1, mitochondrialenzyme
DB00501CimetidineCytochrome P450 2C8enzyme
DB00501CimetidineCytochrome P450 2C9enzyme
DB00501CimetidineCytochrome P450 2E1enzyme
DB00501CimetidineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00501CimetidineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00501CimetidineBile salt export pumptransporter
DB00501CimetidineMultidrug and toxin extrusion protein 2transporter
DB04272Citric acidCell division protein FtsZtarget
DB04272Citric acidAngiogenintarget
DB04272Citric acidBeta-lactamase 2target
DB04272Citric acidUridine-cytidine kinase 2target
DB04272Citric acidTumor necrosis factor ligand superfamily member 13Btarget
DB04272Citric acidBetaine--homocysteine S-methyltransferase 1target
DB04272Citric acidTryptophan--tRNA ligasetarget
DB04272Citric acidAldose reductasetarget
DB04272Citric acidCitrate synthase, mitochondrialtarget
DB04272Citric acidHeparan sulfate glucosamine 3-O-sulfotransferase 3A1target
DB04272Citric acidcGMP-specific 3',5'-cyclic phosphodiesterasetarget
DB04272Citric acidProto-oncogene tyrosine-protein kinase Srctarget
DB04272Citric acidRibonuclease pancreatictarget
DB04272Citric acidIsocitrate dehydrogenase [NADP]target
DB04272Citric acidGlycine N-methyltransferasetarget
DB04272Citric acidEosinophil cationic proteintarget
DB04272Citric acidBeta-lactamasetarget
DB04272Citric acidMolybdenum cofactor guanylyltransferasetarget
DB04272Citric acidFumarate hydratase class IItarget
DB04272Citric acid6-phosphogluconolactonasetarget
DB04272Citric acidOxygen-insensitive NAD(P)H nitroreductasetarget
DB04272Citric acidGag-Pro-Pol polyproteintarget
DB04272Citric acidL-amino-acid oxidasetarget
DB04272Citric acidMacrophage migration inhibitory factortarget
DB04272Citric acidCarboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1target
DB04272Citric acid1-deoxy-D-xylulose 5-phosphate reductoisomerasetarget
DB04272Citric acidTryptophan synthase alpha chaintarget
DB04272Citric acidSialidasetarget
DB04272Citric acidKHG/KDPG aldolasetarget
DB04272Citric acidCytochrome c peroxidasetarget
DB04272Citric acidHepatocyte growth factor-regulated tyrosine kinase substratetarget
DB04272Citric acidInvasintarget
DB04272Citric acidIntron-associated endonuclease 1target
DB04272Citric acidShort tail fiber proteintarget
DB04272Citric acidMalate dehydrogenase, mitochondrialtarget
DB04272Citric acidN5-carboxyaminoimidazole ribonucleotide mutasetarget
DB04272Citric acid50S ribosomal protein L4target
DB04272Citric acidCarboxypeptidase Btarget
DB04272Citric acidHexon proteintarget
DB04272Citric acidRiboflavin biosynthesis protein RibFtarget
DB04272Citric acidBeta-fructosidasetarget
DB04272Citric acidPutative stringent starvation protein Atarget
DB04272Citric acidCitrate synthasetarget
DB04272Citric acidRNA 3'-terminal phosphate cyclasetarget
DB04272Citric acidU6 snRNA-associated Sm-like protein LSm6target
DB04272Citric acidPleckstrin homology domain-containing family A member 1target
DB04272Citric acidFe(3+)-binding periplasmic proteintarget
DB04272Citric acidSignal recognition particle receptor FtsYtarget
DB04272Citric acidNicotinate-nucleotide adenylyltransferasetarget
DB04272Citric acidN utilization substance protein B homologtarget
DB04272Citric acidComplement component C8 gamma chaintarget
DB04272Citric acidRibonucleoside-diphosphate reductase subunit betatarget
DB04272Citric acidGlutamine synthetase 1target
DB04272Citric acidCitrate synthasetarget
DB04272Citric acidProstaglandin F synthasetarget
DB04272Citric acidAdenine phosphoribosyltransferasetarget
DB04272Citric acidGlucose-1-phosphate thymidylyltransferasetarget
DB04272Citric acidGlyoxalase family proteintarget
DB04272Citric acidLaccase domain protein YfiHtarget
DB04272Citric acidRibose-5-phosphate isomerase Atarget
DB04272Citric acidGMP synthase [glutamine-hydrolyzing]target
DB04272Citric acidInosine triphosphate pyrophosphatasetarget
DB04272Citric acidLysozymetarget
DB04272Citric acidGlycerol uptake operon antiterminator regulatory proteintarget
DB04272Citric acid3-carboxy-cis,cis-muconate cycloisomerasetarget
DB04272Citric acidPyruvate decarboxylasetarget
DB04272Citric acidSolute carrier organic anion transporter family member 2B1transporter
DB05351DexlansoprazolePotassium-transporting ATPase alpha chain 1target
DB05351DexlansoprazoleCytochrome P450 2C19enzyme
DB05351DexlansoprazoleCytochrome P450 3A4enzyme
DB05351DexlansoprazolePotassium-transporting ATPase subunit betatarget
DB05351DexlansoprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
DB00736EsomeprazolePotassium-transporting ATPase alpha chain 1target
DB00736EsomeprazoleCytochrome P450 2C19enzyme
DB00736EsomeprazoleCytochrome P450 3A4enzyme
DB00736EsomeprazoleN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
DB00736EsomeprazoleP-glycoprotein 1transporter
DB00736EsomeprazoleSolute carrier family 22 member 8transporter
DB00927FamotidineHistamine H2 receptortarget
DB00927FamotidineSolute carrier family 22 member 2transporter
DB00927FamotidineSolute carrier family 22 member 8transporter
DB00927FamotidineMultidrug and toxin extrusion protein 1transporter
DB00927FamotidineCytochrome P450 1A2enzyme
DB00927FamotidineSolute carrier family 22 member 6transporter
DB09459L-tartaric acidGalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1enzyme
DB09459L-tartaric acidHypoxia-inducible factor 1-alpha inhibitorenzyme
DB09481Magnesium carbonateTransient receptor potential cation channel subfamily M member 6transporter
DB09481Magnesium carbonateSolute carrier family 41 member 3transporter
DB09481Magnesium carbonateMetal transporter CNNM2transporter
DB09481Magnesium carbonateTransient receptor potential cation channel subfamily M member 7transporter
DB09481Magnesium carbonateGlutamate (NMDA) receptortarget
DB00338OmeprazolePotassium-transporting ATPase alpha chain 1target
DB00338OmeprazoleCytochrome P450 2C19enzyme
DB00338OmeprazoleCytochrome P450 3A4enzyme
DB00338OmeprazoleCytochrome P450 2C9enzyme
DB00338OmeprazoleCytochrome P450 1A2enzyme
DB00338OmeprazoleCanalicular multispecific organic anion transporter 2transporter
DB00338OmeprazoleP-glycoprotein 1transporter
DB00338OmeprazoleATP-binding cassette sub-family G member 2transporter
DB00338OmeprazoleCytochrome P450 1A1enzyme
DB00338OmeprazoleCytochrome P450 1B1enzyme
DB00338OmeprazoleCytochrome P450 2C18enzyme
DB00338OmeprazoleCytochrome P450 2C8enzyme
DB00338OmeprazoleCytochrome P450 2D6enzyme
DB00338OmeprazoleAryl hydrocarbon receptortarget
DB01129RabeprazolePotassium-transporting ATPase alpha chain 1target
DB01129RabeprazoleCytochrome P450 3A4enzyme
DB01129RabeprazoleCytochrome P450 2C19enzyme
DB01129RabeprazoleATP-binding cassette sub-family G member 2transporter
DB01129RabeprazoleCytochrome P450 1A1enzyme
DB01129RabeprazoleCytochrome P450 1A2enzyme
DB01129RabeprazoleCytochrome P450 2C9enzyme
DB01129RabeprazoleCytochrome P450 2D6enzyme
DB01129RabeprazoleCytochrome P450 2C8enzyme
DB00863RanitidineHistamine H2 receptortarget
DB00863RanitidineCytochrome P450 1A2enzyme
DB00863RanitidineCytochrome P450 2D6enzyme
DB00863RanitidineSolute carrier family 22 member 1transporter
DB00863RanitidineP-glycoprotein 1transporter
DB00863RanitidineSolute carrier family 22 member 8transporter
DB00863RanitidineCytochrome P450 3A4enzyme
DB00863RanitidineAcetylcholinesterasetarget
DB00863RanitidineSolute carrier family 22 member 2transporter
DB00863RanitidineAcetylcholinesteraseenzyme
DB01390Sodium bicarbonateElectrogenic sodium bicarbonate cotransporter 1transporter
DB01390Sodium bicarbonateSodium bicarbonate cotransporter 3transporter
DB01390Sodium bicarbonateElectroneutral sodium bicarbonate exchanger 1transporter
DB01390Sodium bicarbonateElectrogenic sodium bicarbonate cotransporter 4transporter
DB01390Sodium bicarbonateHydrogen ionstarget
DB01390Sodium bicarbonateSodium-driven chloride bicarbonate exchangertransporter
DB09154Sodium citrateMitochondrial 2-oxodicarboxylate carriertransporter
DB09154Sodium citrateSolute carrier family 13 member 2transporter
DB09154Sodium citrateSolute carrier family 13 member 5transporter
DB09154Sodium citrateTricarboxylate transport protein, mitochondrialtransporter