Refractory Mantle Cell Lymphoma

Also known as: Refractory Mantle Cell Lymphoma (MCL) / Mantle Cell Lymphoma Refractory

DrugDrug NameDrug Description
DB06769BendamustineAn antineoplastic agent used for the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed following rituximab therapy.
DB15699Brexucabtagene autoleucelA modified autologous chimeric antigen receptor (CAR) T cell therapy employing a modified murine anti-CD19 single-chain variable fragment linked to CD28 and CD3ΞΆ co-stimulatory domains for the treatment of patients with relapsed and refractory mantle cell lymphoma.
DB09053IbrutinibAn antineoplastic agent used to treat chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom's Macroglobulinemia.
DB17472PirtobrutinibA kinase inhibitor used to treat relapsed or refractory mantle cell lymphoma (MCL) after at least two lines of systemic therapy.
DrugDrug NamePhaseStatusCount
DB11666Buparlisib0Completed1
DB09053Ibrutinib0Completed1
DB05220Alisertib1Active Not Recruiting1
DB05220Alisertib1Completed1
DB11945Avelumab1Active Not Recruiting1
DB00928Azacitidine1Active Not Recruiting1
DB06769Bendamustine1Not Yet Recruiting1
DB09052Blinatumomab1Active Not Recruiting1
DB00188Bortezomib1Active Not Recruiting1
DB16741Bortezomib D-mannitol1Active Not Recruiting1
DB00958Carboplatin1Active Not Recruiting1
DB00531Cyclophosphamide1Active Not Recruiting1
DB00531Cyclophosphamide1Not Yet Recruiting1
DB00531Cyclophosphamide1Recruiting1
DB00531Cyclophosphamide1Terminated1
DB00773Etoposide1Active Not Recruiting1
DB01073Fludarabine1Not Yet Recruiting1
DB01073Fludarabine1Recruiting1
DB01073Fludarabine1Terminated1
DB09053Ibrutinib1Active Not Recruiting3
DB09053Ibrutinib1Completed1
DB01181Ifosfamide1Active Not Recruiting1
DB00480Lenalidomide1Active Not Recruiting3
DB00480Lenalidomide1Withdrawn1
DB00075Muromonab1Active Not Recruiting1
DB06132Nivolumab1Unknown Status1
DB09035Nivolumab1Unknown Status1
DB08935Obinutuzumab1Active Not Recruiting1
DB09037Pembrolizumab1Completed1
DB11759Pevonedistat1Active Not Recruiting1
DB00073Rituximab1Active Not Recruiting2
DB06176Romidepsin1Completed1
DB06273Tocilizumab1Recruiting1
DB11850Ublituximab1Withdrawn1
DB14989Umbralisib1Withdrawn1
DB15113Utomilumab1Active Not Recruiting1
DB07232Veliparib1Unknown Status1
DB02379Beta-D-Glucose1 / 2Completed1
DB00188Bortezomib1 / 2Completed1
DB16741Bortezomib D-mannitol1 / 2Completed1
DB00262Carmustine1 / 2Completed1
DB12483Copanlisib1 / 2Suspended1
DB00531Cyclophosphamide1 / 2Completed1
DB00531Cyclophosphamide1 / 2Recruiting1
DB00987Cytarabine1 / 2Completed1
DB01234Dexamethasone1 / 2Completed1
DB14844Dordaviprone1 / 2Terminated1
DB00997Doxorubicin1 / 2Completed1
DB01175Escitalopram1 / 2Recruiting1
DB00773Etoposide1 / 2Completed1
DB17573Evorpacept1 / 2Recruiting1
DB01073Fludarabine1 / 2Recruiting1
DB00060Interferon beta-1a1 / 2Not Yet Recruiting1
DB00480Lenalidomide1 / 2Active Not Recruiting1
DB00480Lenalidomide1 / 2Recruiting1
DB00888Mechlorethamine1 / 2Completed1
DB14123Menthol1 / 2Completed1
DB06132Nivolumab1 / 2Active Not Recruiting1
DB09035Nivolumab1 / 2Active Not Recruiting1
DB00635Prednisone1 / 2Completed1
DB00073Rituximab1 / 2Completed2
DB00073Rituximab1 / 2Recruiting1
DB11942Selinexor1 / 2Recruiting1
DB00877Sirolimus1 / 2Completed1
DB06287Temsirolimus1 / 2Completed2
DB11581Venetoclax1 / 2Suspended1
DB00541Vincristine1 / 2Completed1
DB09145Water1 / 2Not Yet Recruiting1
DB11703Acalabrutinib2Recruiting2
DB06769Bendamustine2Recruiting1
DB00531Cyclophosphamide2Completed1
DB00091Cyclosporine2Completed1
DB00987Cytarabine2Recruiting1
DB05094Enzalutamide2Terminated1
DB08899Enzalutamide2Terminated1
DB11684Eprenetapopt2Withdrawn1
DB01073Fludarabine2Completed1
DB16371Glofitamab2Active Not Recruiting1
DB16371Glofitamab2Recruiting1
DB06205Hyaluronidase (human recombinant)2Active Not Recruiting1
DB09053Ibrutinib2Active Not Recruiting1
DB09053Ibrutinib2Completed2
DB09053Ibrutinib2Recruiting1
DB09570Ixazomib2Active Not Recruiting1
DB00480Lenalidomide2Recruiting1
DB16222Loncastuximab tesirine2Recruiting2
DB00688Mycophenolate mofetil2Completed1
DB12340Navitoclax2Recruiting1
DB09035Nivolumab2Active Not Recruiting1
DB08935Obinutuzumab2Active Not Recruiting1
DB08935Obinutuzumab2Completed1
DB08935Obinutuzumab2Recruiting1
DB06306Onalespib2Terminated1
DB15102Pemigatinib2Not Yet Recruiting1
DB17472Pirtobrutinib2Recruiting1
DB12240Polatuzumab vedotin2Active Not Recruiting1
DB00073Rituximab2Active Not Recruiting3
DB00073Rituximab2Recruiting2
DB15044Tafasitamab2Recruiting1
DB06273Tocilizumab2Recruiting1
DB00135Tyrosine2Recruiting2
DB11581Venetoclax2Active Not Recruiting1
DB11581Venetoclax2Recruiting3
DB11581Venetoclax2Withdrawn1
DB15035Zanubrutinib2Completed1
DB17366MB-102 CD123 CARNot AvailableEnrolling by Invitation1