Trigeminal Neuralgia (TN)

Also known as: Tic Douloureux / Trigeminal neuralgia / Trigeminal Neuralgias / Syndrome of paroxysmal facial pain / Neuralgia trigeminal / Tic doloreux

DrugDrug NameDrug Description
DB00564CarbamazepineAn anticonvulsant used to treat various types of seizures and pain resulting from trigeminal neuralgia.
DB01403MethotrimeprazineA phenothiazine used in the management of psychosis, particular those of schizophrenia, and manic phases of bipolar disorder.
DrugDrug NameTargetType
DB00564CarbamazepineVoltage-gated sodium channel alpha subunittarget
DB00564CarbamazepineCytochrome P450 2C8enzyme
DB00564CarbamazepineCytochrome P450 2B6enzyme
DB00564CarbamazepineCytochrome P450 3A4enzyme
DB00564CarbamazepineCytochrome P450 1A2enzyme
DB00564CarbamazepineCytochrome P450 2C19enzyme
DB00564CarbamazepineCytochrome P450 2C9enzyme
DB00564CarbamazepineP-glycoprotein 1transporter
DB00564CarbamazepineCytochrome P450 3A5enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 2B7enzyme
DB00564CarbamazepineRalA-binding protein 1transporter
DB00564CarbamazepineCanalicular multispecific organic anion transporter 1transporter
DB00564CarbamazepineNeuronal acetylcholine receptor subunit alpha-4target
DB00564CarbamazepineNuclear receptor subfamily 1 group I member 2target
DB00564CarbamazepineUDP-glucuronosyltransferase 1-1enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 1-6enzyme
DB00564CarbamazepineUDP-glucuronosyltransferase 1-7enzyme
DB01403MethotrimeprazineDopamine D3 receptortarget
DB01403MethotrimeprazineHistamine H1 receptortarget
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M1target
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M2target
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M3target
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M4target
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M5target
DB01403MethotrimeprazineAlpha-1A adrenergic receptortarget
DB01403MethotrimeprazineAlpha-1B adrenergic receptortarget
DB01403MethotrimeprazineAlpha-1D adrenergic receptortarget
DB01403MethotrimeprazineCytochrome P450 2D6enzyme
DB01403MethotrimeprazineDopamine D2 receptortarget
DB01403MethotrimeprazineDopamine D1 receptortarget
DB01403MethotrimeprazineDopamine D5 receptortarget
DB01403MethotrimeprazineDopamine D4 receptortarget
DB01403MethotrimeprazineAlpha-2A adrenergic receptortarget
DB01403MethotrimeprazineAlpha-2B adrenergic receptortarget
DB01403MethotrimeprazineAlpha-2C adrenergic receptortarget
DB01403Methotrimeprazine5-hydroxytryptamine receptor 2Atarget
DB01403Methotrimeprazine5-hydroxytryptamine receptor 2Ctarget
DB01403MethotrimeprazineCytochrome P450 2E1enzyme
DrugDrug NamePhaseStatusCount
DB11706Raxatrigine1Completed2
DB00083Botulinum toxin type A1 / 2Completed1
DB04077Glycerin1 / 2Terminated1
DB00083Botulinum toxin type A2Recruiting1
DB09157Carbon dioxide2Completed1
DB00514Dextromethorphan2Completed1
DB14039Erenumab2Not Yet Recruiting1
DB01018Guanfacine2Not Yet Recruiting1
DB00281Lidocaine2Not Yet Recruiting1
DB11706Raxatrigine2Completed1
DB12457Rimegepant2Recruiting1
DB00564Carbamazepine2 / 3Completed1
DB00555Lamotrigine2 / 3Completed1
DB01143Amifostine3Unknown Status1
DB00083Botulinum toxin type A3Recruiting1
DB11706Raxatrigine3Not Yet Recruiting1
DB01221Ketamine4Active Not Recruiting1
DB00904Ondansetron4Active Not Recruiting1
DB00776Oxcarbazepine4Withdrawn1
DB00708Sufentanil4Active Not Recruiting1
DB01320FosphenytoinNot AvailableNot Yet Recruiting1
DB12098L-BaclofenNot AvailableCompleted1
DB00555LamotrigineNot AvailableCompleted1
DB00281LidocaineNot AvailableCompleted1