Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 101 - 125 of 14341 in total

Sodium oxybate

Sodium oxybate (Xyrem) is a central nervous system (CNS) depressant used to treat cataplexy or excessive daytime sleepiness associated with narcolepsy. It is a sodium salt of gamma-Hydroxybutyric acid, an endogenous cerebral inhibitory neurotransmitter and a metabolite of the inhibitory neurotransmitter GABA. Due to its physiological effects, sodium oxybate is...
Approved
Matched Description: … Sodium oxybate has been misused to stimulate body growth and to induce euphoria, disinhibition, and sexual ... sodium salt of [gamma-Hydroxybutyric acid], an endogenous cerebral inhibitory neurotransmitter [A251445] and ... A251430] Due to its physiological effects, sodium oxybate is associated with a risk for substance misuse and …

Oxybenzone

Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Approved
Investigational
Matched Description: … It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays …
Matched Mixtures name: … NEST Fragrances Ocean Mist and Coconut Water ... Coppertone Water Babies Pure And Simple Whipped SPF 50 ... Copperstone Water Babies Pure and Simple Whipped Sunscreen Broad Spectrum SPF 50 SPF 50 …

Paraldehyde

Paraldehyde was initially introduced into medical practice in the United Kingdom in 1882 by the Italian physician Vincenzo Cervello. It is classified as a central nervous system (CNS) depressant and has also been found to be an effective anticonvulsant, hypnotic and sedative agent due to its CNS depressant properties. Paraldehyde...
Approved
Investigational
Matched Description: … anticonvulsant, hypnotic and sedative agent due to its CNS depressant properties. ... It is classified as a central nervous system (CNS) depressant and has also been found to be an effective ... some cough medicines as an expectorant, but its efficacy for this indication has not been confirmed and …
Matched Categories: … Hypnotics and Sedatives …

Diethylamino hydroxybenzoyl hexyl benzoate

Diethylamino hydroxybenzoyl hexyl benzoate is a UV filter with high absorption in the UV-A range. Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic photodamage, diethylamino hydroxybenzoyl hexyl benzoate is an oil-soluble UV filter that may be incorporated in the oil phase of...
Approved
Matched Description: … U.S., South America, Mexico, Japan and Taiwan. ... Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic ... Diethylamino hydroxybenzoyl hexyl benzoate was approved in Europe in 2005, and is also marketed in the …
Matched Mixtures name: … P.CALM Water Barrier Suncream ... Kiehls Activated Sun Protector Sunscreen SPF 50 For Face and Body For All Skin Types ... Kiehls Activated Sun Protector Sunscreen SPF 30 For Face and Body For All Skin Types …

Diphenhydramine

Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched Description: … stings, and rashes [L5263, L5266, L5269, F3379]. ... However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269, F3352]. ... receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and …
Matched Mixtures name: … Up and Up Nighttime Flu and Severe Cold and Cough ... Up and Up Flu and Severe Cold and Cough Relief ... Flu and Severe Cold and Cough …
Matched Categories: … Hypnotics and Sedatives ... naproxen and diphenhydramine ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy ... Up and Up Nighttime Sleep-aid …

Testosterone propionate

Testosterone propionate is a slower-releasing anabolic steroid with a short half-life. It is a synthetic androstane steroid derivative of testosterone in the form of 17β propionate ester of testosterone. Testosterone propionate was developed initially by Watson labs, and FDA approved on February 5, 1974. Currently, this drug has been discontinued...
Approved
Investigational
Vet approved
Withdrawn
Matched Description: … [T83] Testosterone propionate was developed initially by Watson labs, and FDA approved on February 5, …
Matched Categories: … Testosterone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Loratadine

Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Approved
Investigational
Matched Description: … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation …
Matched Mixtures name: … Up and Up allergy and congestion relief ... Loratadine and Pseudoephedrine ... Smart Sense allergy and congestion relief indoor and outdoor allergies …
Matched Categories: … Loratadine and derivatives …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy Relief ... Up and Up Childrens Allergy Relief …

Fexofenadine

Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. It is selective for the H1 receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier - this is in contrast to previous first-generation antihistamines, such as diphenhydramine, which readily bind to off-targets...
Approved
Investigational
Matched Description: … L4269] It is selective for the H1 receptor, carries little-to-no activity at off-targets, and ... [A1452] Fexofenadine is the major active metabolite of [terfenadine][A1495] and is administered as a …
Matched Mixtures name: … Allergy and Congestion ... Allergy and Congestion ... Allegra-D Allergy and Congestion …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy Relief ... Up and Up Non Drowsy Allergy Relief …

Metformin

Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin...
Approved
Matched Description: … It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and ... a clinically significant reduction of plasma fasting insulin levels. ... Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management …
Matched Mixtures name: … Glyburide and Metformin ... Glyburide and Metformin ... Glyburide and Metformin …
Matched Categories: … metformin and acarbose ... Alimentary Tract and Metabolism ... metformin and evogliptin ... metformin and gemigliptin ... metformin and linagliptin …

Chromium

Chromium is a transition element with the chemical symbol Cr and atomic number 24 that belongs to Group 6 of the periodic table. It is used in various chemical, industrial and manufacturing applications such as wood preservation and metallurgy. The uses of chromium compounds depend on the valency of chromium,...
Approved
Matched Description: … an essential dietary trace element as it is involved in metabolism of blood glucose, regulation of insulin ... It is used in various chemical, industrial and manufacturing applications such as wood preservation and ... resistance and metabolism of lipids. …
Matched Mixtures name: … Chromium and Vanadium (combo) ... Vitamin and Mineral Drink Mix ... Prenatal Vitamin and Mineral Supplement …
Matched Categories: … Diet, Food, and Nutrition …

Bronopol

Bronopol, or 2-Bromo-2-nitro-1,3-propanediol, is an organic compound with wide-spectrum antimicrobial properties. First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was registered in the United States in 1984 for use in industrial bactericides, slimicides and preservatives . Bronopol is used as a microbicide or microbiostat...
Approved
Matched Description: … including oil field systems, air washer systems, air conditioning or humidifying systems, cooling water ... First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was ... Bronopol is used as a microbicide or microbiostat in various commercial and industrial applications, …
Matched Categories: … Indicators and Reagents …

Copper oxodotreotide Cu-64

Copper Cu 64 dotatate is a newly approved Cu labeled somatostatin analog and has several advantages over 68Ga-labeled somatostatin analogs for positron emission tomography (PET). Copper Cu 64 dotatate has a longer half-life and can be produced once a day as opposed to several times a day, and lower positron...
Approved
Matched Description: … times a day, and lower positron energy lending to improved spatial resolution. ... Copper Cu 64 dotatate is a newly approved Cu labeled somatostatin analog and has several advantages over ... [A220348] Copper Cu 64 dotatate has a longer half-life and can be produced once a day as opposed to several …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Donislecel

Donislecel is the first allogeneic pancreatic islet cellular from deceased donor pancreatic cells used for the treatment of adult type 1 diabetes with unsuccessful control of glycated hemoglobin, despite intensive diabetes management and treatments.[L47166,L47196] The primary mechanism of action of donislecel is attributed to the secretion of insulin and other...
Approved
Matched Description: … needing insulin for 1 to 5 years and 10 patients for more than 5 years. ... thus unable to prevent further hypoglycemia, by not relying on exogenous and intentional insulin administration ... and homeostasis. …
Matched Categories: … Cellular and Gene Therapy …

Meradimate

Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an...
Approved
Matched Description: … Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products …
Matched Mixtures name: … Bull Frog Water Armor Super 40 ... BullFrog Water Armor Sport Super ... Principal Secret Reclaim Sunscreen For Face and Body SPF 30 …

Formestane

Formestane was the first selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. Formestane suppresses estrogen production from anabolic steroids or prohormones. Formestane is also a prohormone of 4-hydroxytestosterone, an active steroid with weak androgenic activity and mild aromatase inhibitor activity....
Approved
Investigational
Withdrawn
Matched Description: … and less expensive than formestane, formestane lost popularity. ... With the discovery of newer, non-steroidal and steroidal, aromatase inhibitors which were orally active ... Formestane is also a prohormone of 4-hydroxytestosterone, an active steroid with weak androgenic activity and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Polythiazide

A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)
Approved
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. …
Matched Categories: … polythiazide and potassium ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Lamotrigine

Lamotrigine is an antiepileptic drug belonging in the phenyltriazine class. It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. It...
Approved
Investigational
Matched Description: … It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. ... Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval ... [A191350] Lamotrigine has relatively few side-effects and does not require laboratory monitoring. …
Matched Categories: … Calcium-Regulating Hormones and Agents …

Loperamide

Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid that is structurally similar to opiate receptor agonists such as diphenoxylate and haloperidol. Due to...
Approved
Matched Description: … withdrawal symptoms and to induce euphoria. ... [L42785] The drug was first synthesized in 1969 and used medically in 1976. ... [A6249] Due to pharmacological properties, loperamide has been misused and abused to self-manage opioid …
Matched Mixtures name: … Anti Diarrheal and Anti Gas ... Anti Diarrheal and Anti Gas ... Up and Up Anti Diarrheal Anti Gas …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up anti diarrheal ... Berkley and Jensen Anti Diarrheal ... Foster and Thrive Anti-diarrheal …

Glipizide

Glipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus. It was first introduced in 1984 and is available in various countries including Canada and the U.S. According to the 2018 Clinical Practice...
Approved
Investigational
Matched Description: … It was first introduced in 1984 [A179491] and is available in various countries including Canada and ... [A179485] Glipizide was first approved by the FDA in 1994 and is available in extended-release tablets ... onset of action with the shortest half-life and duration of action, reducing the risk for long-lasting …
Matched Mixtures name: … Glipizide and Metformin HCl ... Glipizide and Metformin HCl ... Glipizide and Metformin Hydrochloride …
Matched Categories: … Insulin Secretagogues ... Alimentary Tract and Metabolism …

Methylprednisolone hemisuccinate

A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Approved
Matched Description: … A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Crotalus scutulatus antivenin

Crotalus scutulatus antivenin is derived and purified immunoglobulin fragments obtained from other domestic animals such as sheep previously immunized with Crotalus scutulatus (also known as the Mojave rattlesnake ). The final purified antivenin product is obtained by mixing other different monospecific snake antivenins and isolating the antivenin of interest through...
Approved
Experimental
Matched Description: … isolating the antivenin of interest through fractionation and chromatography techniques. ... Crotalus scutulatus antivenin is derived and purified immunoglobulin fragments obtained from other domestic ... Mojave rattlesnakes inhabit desert areas of the southwestern United States and central Mexico. …

Rosiglitazone

Rosiglitazone is an anti-diabetic drug in the thiazolidinedione class of drugs. It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl). Like other thiazolidinediones, the mechanism of action of rosiglitazone is by activation of the intracellular receptor...
Approved
Investigational
Matched Description: … Apart from its effect on insulin resistance, it appears to have an anti-inflammatory effect: nuclear ... Rosiglitazone is a selective ligand of PPARγ, and has no PPARα-binding action. ... factor kappa-B (NFκB) levels fall and inhibitor (IκB) levels increase in patients on rosiglitazone. …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and rosiglitazone ... glimepiride and rosiglitazone …

Conivaptan

Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). It was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH). Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2).
Approved
Investigational
Matched Description: … Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2). …

Calcium ascorbate

Approved
Nutraceutical
Matched Mixtures name: … and Succinic Acid ... Threonate and Succinic Acid ... Vitamin C and Calcium Tab …
Matched Categories: … Vitamin C and analogues ... Diet, Food, and Nutrition …
Matched Products: … Ester-C With Non-medicinal Bioflavonoids, Quercetin, and Grape Seed Extract …

Vitamin E

In 1922, vitamin E was demonstrated to be an essential nutrient . Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol being the most biologically active . Vitamin E acts as an antioxidant, protecting cell membranes from oxidative damage . The antioxidant effects...
Approved
Nutraceutical
Vet approved
Matched Description: … Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol ... for use in the treatment of diseases causing bone loss, cardiovascular diseases, diabetes mellitus and ... Though this research is so far inconclusive, vitamin E remains a popular supplement and is generally …
Matched Mixtures name: … Vitamin E and Coq10 ... Multi Vitamin and Fluoride ... Multi Vitamin and Fluoride …
Matched Categories: … Basic Ointments and Protectants ... Diet, Food, and Nutrition …
Matched Products: … Vitamin E 1000 Iu - Water Soluble …
Displaying drugs 101 - 125 of 14341 in total