Negative Inotrope
- Name
- Negative Inotrope
- Accession Number
- DBCAT005659
- Description
Any compounds or agents that weaken the force of muscle contraction, but most commonly in the context of the heart muscle.
- Drugs
Drug Drug Description Diltiazem A calcium channel blocker used to treat hypertension and to manage chronic stable angina. Verapamil A non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension. Quinidine A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias. Procainamide A medication used to treat life threatening ventricular arrhythmias. Disopyramide A class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias. Flecainide A class Ic antiarrhythmic agent used to manage atrial fibrillation and paroxysmal supraventricular tachycardias (PSVT). Propranolol A non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma. Carteolol A beta adrenergic antagonist used to treat arrhythmia, angina, hypertension, and glaucoma. Labetalol An alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome. Bucindolol Bucindolol has been investigated in Heart Failure. Carvedilol A non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients. Nadolol A non-selective beta-adrenergic antagonist used for the management of arrhythmias, angina pectoris, and hypertension. Oxprenolol A non-selective beta-adrenergic antagonist used to treat hypertension, angina pectoris, arrhythmias, and anxiety. Penbutolol A beta-adrenergic antagonist used for the management of mild to moderate arterial hypertension, alone or in combination with other antihypertensive agents. Nifedipine A dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension. Lidoflazine Not Annotated Perhexiline For the management of severe angina pectoris. - Drugs & Drug Targets