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Displaying drugs 26 - 50 of 11272 in total
A barbiturate that is metabolized to phenobarbital. It has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.
Approved
Matched Synonyms: … 5-ethyl-1-methyl-5-phenylbarbituric acid ... 5-Ethyl-1-methyl-5-phenyl-pyrimidine-2,4,6-trione ... 5-ethyl-1-methyl-5-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione …
Matched Iupac: … 5-ethyl-1-methyl-5-phenyl-1,3-diazinane-2,4,6-trione …
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in...
Approved
Matched Synonyms: … (R)-(6-methoxyquinolin-4-yl)((2S,4S,8R)-8-vinylquinuclidin-2-yl)methanol …
Matched Iupac: … (R)-[(1S,2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol …
Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.
Approved
Investigational
Matched Synonyms: … pentyl 1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate ... Pentyl [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamate ... (1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-carbamic acid pentyl ester …
Matched Iupac: … pentyl N-{1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl …
Matched Products: … XELTABIN 500 MG FILM KAPLI TABLET, 20 ADET ... CAPETABIN 500 MG FILM KAPLI TABLET ,1TABLET, 20 ADET …
The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Approved
Investigational
Matched Synonyms: … (3β,14β,17α)-cholest-5-en-3-ol ... Cholest-5-en-3beta-ol …
Sulfaphenazole is a sulfonamide antibacterial.
Approved
Matched Synonyms: … 3-(p-aminobenzenesulfonamido)-2-phenylpyrazole ... 1-phenyl-5-sulfanilamidopyrazole ... 5-sulfanilamido-1-phenylpyrazole …
Matched Iupac: … 4-amino-N-(1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide …
Latanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. Latanoprost is the first topical prostaglandin F2 alpha analog used for glaucoma treatment. It has been found to be well-tolerated and its use...
Approved
Investigational
Matched Synonyms: … isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate ... propan-2-yl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoate …
Matched Iupac: … propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate …
Matched Mixtures name: … Xalacom 50 Mikrogramm/ml + 5 mg/ml Augentropfen ... LATANOPROST 0.05 MG/ML AND TIMOLOL 5 MG/ML SANDOZ EYE DROPS ... LatanoTim-Vision 50 Mikrogramm/ml + 5 mg/ml Augentropfen …
Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various chemical pathways [A32991, L2729]. Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism...
Approved
Investigational
Matched Synonyms: … (S)-(−)-2-pyrrolidone-5-carboxylic acid ... (S)-pyroglutamic acid ... 5-L-oxoproline …
Matched Iupac: … (2S)-5-oxopyrrolidine-2-carboxylic acid …
Matched Salts cas: … 62003-27-4 ... 54571-67-4
Copanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity against the alpha and delta isoforms. PI3K, a lipid kinase that activates downstream signalling pathways involved in cell survival and growth, that exists in different isoforms and is often overexpressed in hematological malignancies. Copanlisib was granted accelerated...
Approved
Investigational
Matched Synonyms: … 2-AMINO-N-(7-METHOXY-8-(3-(MORPHOLIN-4-YL)PROPOXY)-2,3-DIHYDROIMIDAZO(1,2-C)QUINAZOLIN-5-YL(PYRIMIDINE ... 2-AMINO-N-(7-METHOXY-8-(3-MORPHOLIN-4-YLPROPOXY)-2,3-DIHYDROIMIDAZO(1,2-C)QUINAZOLIN-5-YL)PYRIMIDINE- ... 5-PYRIMIDINECARBOXAMIDE, 2-AMINO-N-(2,3-DIHYDRO-7-METHOXY-8-(3-(4-MORPHOLINYL)PROPOXY)IMIDAZO(1,2-C)QUINAZOLIN …
Matched Iupac: … 2-amino-N-{7-methoxy-8-[3-(morpholin-4-yl)propoxy]-2H,3H-imidazo[1,2-c]quinazolin-5-yl}pyrimidine-5-carboxamide …
Matched Description: … Copanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity …
Matched Categories: … Phosphatidylinositol-3-kinase (Pi3K) inhibitors …
Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) . It was initially approved in the USA in 1990's for the treatment of NSCLC . It is a third-generation vinca alkaloid. The introduction...
Approved
Investigational
Matched Synonyms: … 5'-Noranhydrovinblastine …
Matched Iupac: … -diazatetracyclo[12.3.1.0^{3,11}.0^{4,9}]octadeca-3(11),4,6,8,15-pentaen-12-yl]-10-hydroxy-5-methoxy- ... methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(12S,14R)-16-ethyl-12-(methoxycarbonyl)-1,10 …
Matched Description: … It was initially approved in the USA in 1990's for the treatment of NSCLC [L2010]. …
Matched Products: … NAVELBINE 20 MG ... NAVELBINE® 20 MG ... Navelbine 20 mg - Kapseln …
A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. It does not...
Approved
Vet approved
Matched Synonyms: … 2-Thio-5-ethyl-5-sec-pentylbarbituric acid ... 5-Ethyl-5-(1-methyl-butyl)-2-thioxo-dihydro-pyrimidine-4,6-dione …
Matched Iupac: … 5-ethyl-5-(pentan-2-yl)-2-sulfanylidene-1,3-diazinane-4,6-dione …
Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts...
Approved
Vet approved
Matched Synonyms: … 5-Nitrofurantoin ... 1-((5-nitrofurfurylidene)amino)hydantoin ... N-(5-Nitrofurfurylidene)-1-aminohydantoin …
Matched Iupac: … 1-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]imidazolidine-2,4-dione …
Matched Salts cas: … 54-87-5
Matched Products: … PIYELOSEPTYL 25 MG/5 ML ORAL SUSPANSIYON, 100 ML ... PIYELOSEPTYL 25 MG/5 ML ORAL SUSPANSIYON, 200 ML ... PIYELOSEPTYL 25 MG/5 ML ORAL SUSPANSIYON, 300 ML …
A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.
Approved
Matched Synonyms: … [4S-(4α,4aα,5aα,6β,12aα)]-7-chloro-4-(dimethylamino)1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy …
Matched Iupac: … (4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene …
Matched Salts cas: … 64-73-3 ... 17146-81-5
A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Approved
Vet approved
Matched Synonyms: … 5-(propylthio)-2-carbomethoxyaminobenzimidazole ... O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate ... (5-(propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester …
Matched Products: … ALBENDAZOL 400 MG/20 ML SUSPENSIÓN ... HELMADOL 400 MG FİLM KAPLI TABLET, 3 ADET ... ANDAZOL 200 MG/10 ML SÜSPANSİYON, 20 ML …
Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes mellitus. It works to block glucose reabsorption from the glomerulus. Ertugliflozin was first approved by the FDA in December 2017.[A261951, L1132] It was also approved by the European Commission in March 2018.
Approved
Investigational
Matched Synonyms: … (1S,2S,3S,4R,5S)-5-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane ... 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-β-L-idopyranose ... β-L-Idopyranose, 1,6-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)- …
Matched Iupac: … (1S,2S,3S,4R,5S)-5-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1 …
Matched Salts cas: … 1210344-83-4
Matched Products: … สเตกลาโตร (5 มิลลิกรัม) …
Approved
Matched Synonyms: … 7-(5-oxohexyl)theophylline …
Matched Iupac: … 1,3-dimethyl-7-(5-oxohexyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to Trichophyton rubrum or Trichophyton mentagrophytes infection. Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis...
Approved
Investigational
Matched Synonyms: … 5-Fluoro-2,1-benzoxaborol-1(3H)-ol ... 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole …
Matched Iupac: … 5-fluoro-1,3-dihydro-2,1-benzoxaborol-1-ol …
A benzodiazepine used to treat various seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop.[FDA Label][L5572,F3763,F3787,F3796] The agent has also been indicated for treating panic disorder.[FDA Label][A175438,L5572,F3763,F3787,F3796] The mechanism of action appears to involve the enhancement of gamma-aminobutyric acid receptor responses.[FDA Label][A175438,A175441,L5572,F3763,F3787,F3796] Since being...
Approved
Illicit
Matched Synonyms: … 1,3-dihydro-7-nitro-5-(2-chlorophenyl)-2H-1,4.benzodiazepin-2-one ... 5-(2-chlorophenyl)-7-nitro-1H-benzo[e][1,4]diazepin-2(3H)-one ... 5-(2-chloro-phenyl)-7-nitro-1,3-dihydro-benzo[e][1,4]diazepin-2-one …
Matched Iupac: … 5-(2-chlorophenyl)-7-nitro-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Products: … GABACLOTEC-S ... RIVOTRIL 1 MG/1 ML IV ÇÖZELTİ İÇEREN AMPUL, 5 ADET …
Berotralstat is a selective inhibitor of plasma kallikrein used in the prophylaxis of attacks of hereditary angioedema (HAE). It works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE. Berotralstat is strictly used to...
Approved
Matched Synonyms: … 2-[3-(aminomethyl)phenyl]-N-[5-[(R)-(3-cyanophenyl)-(cyclopropylmethylamino)methyl]-2-fluorophenyl]-5 ... (+)-1-(3-(aminomethyl) phenyl)-N-(5-((3-cyanophenyl)(cyclopropylmethylamino)methyl)-2-fluorophenyl)-3 ... 3- (trifluoromethyl)-1H-pyrazole-5-carboxamide dihydrochloride …
Matched Iupac: … 3-(trifluoromethyl)-1H-pyrazole-5-carboxamide ... 1-[3-(aminomethyl)phenyl]-N-{5-[(R)-(3-cyanophenyl)[(cyclopropylmethyl)amino]methyl]-2-fluorophenyl}- …
Matched Description: … [A225106] Berotralstat was first approved by the FDA on December 3, 2020, as the first once-daily oral …
Matched Salts cas: … 1809010-52-3
Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation and its off-label use in the treatment of serotonin syndrome.
Approved
Matched Synonyms: … 4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine ... 1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine ... 4-Dibenzo[a,d]cyclohepten-5-ylidene-1-methyl-piperidine …
Matched Iupac: … 1-methyl-4-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-ylidene}piperidine …
Matched Salts cas: … 969-33-5
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …
Matched Products: … SIPRAKTIN TABLET , 20 ADET ... ไซโปร-4 เอ็นแอล ... PILIAN TABLET 4 mg …
Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the...
Approved
Investigational
Matched Synonyms: … 2',4'-difluoro-4-hydroxy-3-biphenylcarboxylic acid ... 5-(2,4-difluorophenyl)salicylic acid ... 2-(hydroxy)-5-(2,4-difluorophenyl)benzoic acid …
Matched Iupac: … 2',4'-difluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid …
Matched Products: … DOLPHIN 250 MG FILM TABLET, 20 TABLET …
Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA).[L39065, A255582] Metabolized by intestinal bacteria, sulfasalazine is broken down into mesalazine and sulfapyridine, 2 compounds that carry out the main pharmacological...
Approved
Matched Synonyms: … 4-(Pyridyl-2-amidosulfonyl)-3'-carboxy-4'-hydroxyazobenzene ... 5-(4-(2-Pyridylsulfamoyl)phenylazo)-2-hydroxybenzoic acid ... 2-Hydroxy-5-[4-(pyridin-2-ylsulfamoyl)-phenylazo]-benzoic acid …
Matched Iupac: … 2-hydroxy-5-[(E)-2-{4-[(pyridin-2-yl)sulfamoyl]phenyl}diazen-1-yl]benzoic acid …
Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin. Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. It has the ability to reduce ocular hypotension, proving effective in conditions such as...
Approved
Investigational
Matched Synonyms: … (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide …
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-N-ethylhept ... -5-enamide …
Matched Mixtures name: … GANFORT % 0,03 + % 0,5 GÖZ DAMLASI, ÇÖZELTİ, 3 ML ... BimatoTim-Vision 0,3 mg/ml + 5 mg/ml Augentropfen, Lösung ... BEMATORİN-T 0,3 MG + 5 MG/1 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET …
Matched Products: … BEMATORIN %0.03 GÖZ DAMLASI,3 ML ... LUMIGAN % 0,03 GÖZ DAMLASI, ÇÖZELTİ, 3 ML …
Tiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly arthritis pain. It belongs to the arylpropionic acid (profen) group of nonsteroidal anti-inflammatory drugs (NSAIDs).
Approved
Matched Synonyms: … 2-(5-Benzyl-2-thienyl)propionsäure ... 2-(5-Benzoyl-thiophen-2-yl)-propionic acid ... 5-benzoyl-α-methyl-2-thiopheneacetic acid …
Matched Iupac: … 2-(5-benzoylthiophen-2-yl)propanoic acid …
Matched Products: … SURGAM 300 MG TABLET, 20 ADET ... SURGAM RETARD 300 MG TABLET, 20 ADET …
Zopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors. In addition to zopiclone's benzodiazepine pharmacological properties it also has some barbiturate-like properties.
Approved
Matched Synonyms: … 6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methyl-1-piperazinecarboxylate …
Matched Iupac: … 6-(5-chloropyridin-2-yl)-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate …
Matched Products: … IMOVANE 7.5 MG FİLM KAPLI TABLET, 5 ADET ... IMOVANE 7.5 MG FİLM KAPLI TABLET, 20 ADET …
A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.
Approved
Matched Synonyms: … (5'α)-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotoman-3',6',18-trione ... 12'-hydroxy-2'-methyl-5'α-(phenylmethyl)ergotaman-3',6',18-trione ... 12'-Hydroxy-2'-methyl-5'alpha-(phenylmethyl)ergotaman-3',6',18-trione …
Matched Iupac: … (4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6}] ... -4-carboxamide ... dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene …
Matched Salts cas: … 379-79-3
Matched Mixtures name: … ERGO SANOL DRAJE , 20 ADET ... AVMIGRAN FİLM TABLET, 20 ADET …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings ... Serotonin 5-HT1 Receptor Agonists ... Serotonin 5-HT2 Receptor Agonists …
Matched Products: … ERGAFEIN DRAJE, 20 ADET …
Displaying drugs 26 - 50 of 11272 in total